Abstract:
:Gestational diabetes is a common pregnancy disorder which is generally managed with diet, exercise, metformin or insulin treatment and which usually resolves after delivery of the infant. Identifying and treating gestational diabetes improves maternal and fetal outcomes and allows for health promotion to reduce the mother's risk of type 2 diabetes in later life. However, there remains considerable controversy about the optimal method of identification and diagnosis of women with gestational diabetes. The NICE-2015 diagnostic criteria (75 g oral glucose tolerance test (OGTT) 0 h ≥5.6 mmol/L; 2 h ≥7.8 mmol/L) are based upon cost-effectiveness estimates using observational data, while the WHO-2013 criteria (75 g OGTT 0 h ≥5.1 mmol/L; 1 h ≥10.0 mmol/L; 2 h ≥8.5 mmol/L) identify women and infants at risk of adverse outcomes according to prospective data. There is also considerable controversy about testing for gestational diabetes using universal or risk factor-based screening, and when and how testing should be performed. The aim of this review is to provide a summary of the clinical biochemistry aspects to these debates and to highlight the importance of appropriate identification of gestational diabetes and subsequent type 2 diabetes in this population.
journal_name
Ann Clin Biochemjournal_title
Annals of clinical biochemistryauthors
Meek CLdoi
10.1177/0004563216674743subject
Has Abstractpub_date
2017-01-01 00:00:00pages
33-42issue
1eissn
0004-5632issn
1758-1001pii
0004563216674743journal_volume
54pub_type
杂志文章,评审abstract::This paper reviews the physiology and pathology of oxygen transport from the atmosphere to the cells in critically ill patients. A thorough understanding of this allows a rational approach to monitoring and managing an hypoxic patient in the intensive care setting. ...
journal_title:Annals of clinical biochemistry
pub_type: 指南,杂志文章,评审
doi:10.1177/000456329102800104
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abstract::A 19-year-old man who developed extensive oesophageal lye (Alkali) stricture and received long-term enteral nutrition (eight months) with a jejunostomy tube developed macrocytic anaemia (Hb: 41 g/L) with leucopenia (white blood cell [WBC]: 3.0 x 10(9)/L). The patient's serum vitamin B12, folate, iron and liver functio...
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journal_title:Annals of clinical biochemistry
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journal_title:Annals of clinical biochemistry
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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更新日期:2002-03-01 00:00:00
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journal_title:Annals of clinical biochemistry
pub_type: 杂志文章,评审
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journal_title:Annals of clinical biochemistry
pub_type: 杂志文章
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journal_title:Annals of clinical biochemistry
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