Exercise Intensity and Incidence of Metabolic Syndrome: The SUN Project.

Abstract:

INTRODUCTION:Emerging evidence suggests that vigorous physical activity may be associated with higher cardioprotective benefits than moderate physical activity. This study aimed to assess the long-term relationship between the intensity of leisure time physical activity (LTPA) and the risk of developing metabolic syndrome (MS) in a prospective cohort study. METHODS:The Seguimiento Universidad de Navarra (SUN) Project comprises Spanish university graduates. Participants (n=10,145) initially free of MS were followed for a minimum of 6 years (2008-2014). Analysis was conducted in 2015. Physical activity was assessed though a validated questionnaire. The intensity of each physical activity was measured in METs. The intensity of LTPA was estimated by the ratio between total METs/week and total hours of LTPA/week, obtaining the mean METs/hour of LTPA. MS was defined according to the harmonizing definition. The association between the intensity of LTPA (METs/hour) and MS was assessed with logistic regression models adjusting for potential confounders. RESULTS:Among 10,145 participants initially free of any MS criteria, 412 new MS cases were observed. Vigorous LTPA was associated with a 37% relatively lower risk (AOR=0.63, 95% CI=0.44, 0.89) compared with light LTPA. For a given total energy expenditure, independent of the time spent on it, participants who performed vigorous LTPA exhibited a higher reduction in the risk of MS than those who performed light to moderate LTPA. CONCLUSIONS:Vigorous LTPA was significantly associated with lower risk of developing MS after a 6-year follow-up period.

journal_name

Am J Prev Med

authors

Hidalgo-Santamaria M,Fernandez-Montero A,Martinez-Gonzalez MA,Moreno-Galarraga L,Sanchez-Villegas A,Barrio-Lopez MT,Bes-Rastrollo M

doi

10.1016/j.amepre.2016.11.021

subject

Has Abstract

pub_date

2017-04-01 00:00:00

pages

e95-e101

issue

4

eissn

0749-3797

issn

1873-2607

pii

S0749-3797(16)30622-5

journal_volume

52

pub_type

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