A Case Report of the Resolution of Multiple Recalcitrant Verrucae in a Renal Transplant Recipient After a Mycophenolate Mofetil Dose Reduction.


:Renal transplant recipients are at an increased risk of developing verrucae due to chronic immunosuppression, and certain therapies may confer a greater risk. Herein, we describe a 51-year-old woman with a 10-year-old unrelated kidney transplant who developed numerous therapy-resistant verrucae while on mycophenolate mofetil and tacrolimus maintenance immunosuppression. Over several years of immunosuppressant therapy, she declined the approach of reducing her mycophenolate mofetil dose to potentially improve her verrucae. Unfortunately, she later developed graft rejection requiring reversion to peritoneal dialysis. Within months of reducing her mycophenolate mofetil dose (her tacrolimus dose remained unchanged), she experienced dramatic resolution of many of her verrucae. In the current case, the observed clinical improvement may have resulted from either the total reduction of immunosuppression or the specific reduction of mycophenolate mofetil. Consequently, mycophenolate mofetil may contribute to the refractory nature of verrucae within renal transplant recipients, and further research should determine the relationship between verrucae development and both specific immunosuppressant therapies and the degree of immunosuppression.


Transplant Proc


Ash MM,Jolly PS




Has Abstract


2017-01-01 00:00:00














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    pub_type: 杂志文章,评审


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    pub_type: 杂志文章


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    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Yanishi M,Kinoshita H,Tsukaguchi H,Kimura Y,Koito Y,Jino E,Watanabe M,Sugi M,Matsuda T

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    journal_title:Transplantation proceedings

    pub_type: 杂志文章


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    更新日期:2005-06-01 00:00:00

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    journal_title:Transplantation proceedings

    pub_type: 杂志文章,评审


    authors: Durante-Mangoni E,Casillo R,Pinto D,Caianiello C,Albisinni R,Caprioli V,Maiello C,Utili R

    更新日期:2011-01-01 00:00:00

  • Late spontaneous kidney graft decapsulation after administration of sirolimus in a recipient with chronic hepatitis B and C infection: a case report.

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    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Yang MH,Loong CC,Wu CW,Lui WY

    更新日期:2008-09-01 00:00:00

  • Modulation of T-dependent cell-mediated immune responses by antigen-reactive cell opsonization and active suppression.

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    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Bonavida B,Hutchinson IV

    更新日期:1978-03-01 00:00:00

  • Application of an artificial neural network model to predict delayed decrease of serum creatinine in pediatric patients after kidney transplantation.

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    journal_title:Transplantation proceedings

    pub_type: 杂志文章


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    更新日期:2007-07-01 00:00:00

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    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Fujikawa T,Fujita S,Mekeel KL,Reed AI,Foley DP,Kim RD,Howard RJ,Hemming AW

    更新日期:2006-12-01 00:00:00

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    abstract::In orthotopic liver transplantation, particular emphasis must be placed on the unique physiologic, pathologic, and clinical features in residents living in areas at high vs low altitude. Hypobaric hypoxia, hypothermia, heavy radiation, high wind speed, and superevaporation at high altitudes may lead to various disease...

    journal_title:Transplantation proceedings

    pub_type: 杂志文章


    authors: Jin S,Chen Z,Lunan Y,Zeng Y,Wen T,Li B,Zhao J,Wang W,Xu M,Yang J

    更新日期:2009-06-01 00:00:00