Abstract：
:This article describes the history of visual prostheses, with emphasis on the development of the Argus II retinal prosthesis system (Second Sight Medical Products, Inc., Sylmar, CA). A brief overview of cortical electrical stimulation in the blind is provided, followed by an account of the design and development of retinal stimulation equipment at the Duke Eye Center in the late 1980s; the first human intraoperative tests there and the subsequent 8 years of tests at the Wilmer Eye Institute; the transfer of the project to the Doheny Eye Institute at the University of Southern California and the founding of Second Sight Medical Products; and the development and clinical trials of the Argus I and Argus II systems. In a series of vignettes, we pay tribute to the many colleagues and patient volunteers without whose help the work would not have been possible.
journal_name
Ophthalmologyjournal_title
Ophthalmologyauthors
Humayun MS,de Juan E Jr,Dagnelie Gdoi
10.1016/j.ophtha.2016.06.044subject
Has Abstractpub_date
2016-10-01 00:00:00pages
S89-S97issue
10Seissn
0161-6420issn
1549-4713pii
S0161-6420(16)30512-7journal_volume
123pub_type
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