Abstract：
OBJECTIVE:Physical complaints such as faintness, dizziness, cold limbs and headaches have been well-established in chronic low blood pressure (hypotension). This study investigated the occurrence of adverse emotional states and the symptoms of depression in this condition. As autonomic dysregulation, particularly diminished sympathetic tone, is believed to be involved in the etiology of hypotension, the impact of different facets of autonomic cardiovascular control on mood and depressive symptoms was also explored. METHODS:Forty individuals with chronic hypotension and forty normotensive control persons were presented with the Mood Scale and Beck Depression Inventory. Stroke volume, cardiac output, pre-ejection period, Heather index and aortic peak blood flow velocity were recorded under resting conditions as indices of beta-adrenergic inotropic drive. Respiratory sinus arrhythmia and baroreflex sensitivity were additionally obtained. RESULTS:Hypotensive individuals scored markedly higher on both questionnaire scales than controls, indicating an adversely affected emotional state and more severe depressive symptoms. In the entire sample, cardiac output, Heather index, and aortic peak blood flow velocity correlated negatively with the questionnaire scores; according to regression analysis, the Heather index explained the largest proportion of test score variance. CONCLUSION:Although hypotension does not constitute a serious medical condition, the findings of an adverse affective state and increased burden with depressive symptoms corroborate the view that it can have a considerable impact on wellbeing and quality of life. The correlations of the beta-adrenergic indices with the questionnaire scales indicate that cardiac sympathetic regulation plays a key role in the psychophysiological mediation of hypotension-related mood impairment.
journal_name
J Psychosom Resjournal_title
Journal of psychosomatic researchauthors
Duschek S,Hoffmann A,Reyes Del Paso GAdoi
10.1016/j.jpsychores.2016.12.008subject
Has Abstractpub_date
2017-02-01 00:00:00pages
33-40eissn
0022-3999issn
1879-1360pii
S0022-3999(16)30585-2journal_volume
93pub_type
杂志文章abstract：:To determine the effects of exercise training programs on psychosocial improvement in uncomplicated postmyocardial infarction patients, 210 male patients hospitalized for an acute myocardial infarction (MI) were randomized to three week symptom limited treadmill (TM) plus home exercise training, TM plus medically supe...
journal_title：Journal of psychosomatic research
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：Journal of psychosomatic research
pub_type： 杂志文章
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pub_type： 杂志文章,评审
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