ABO incompatible renal transplantation following lung transplantation.

Abstract:

:We present management strategies utilised for the first case of an urgent live-donor ABO incompatible B blood group renal transplant, in a patient with a prior A blood group lung transplant for cystic fibrosis. Three years on, renal function is excellent and stable, whilst lung function has improved.

journal_name

Transpl Immunol

journal_title

Transplant immunology

authors

Snell GI,Davis AK,Menahem S,Kotecha S,Whitford HM,Levvey BJ,Paraskeva M,Webb A,Westall GW,Walker RG

doi

10.1016/j.trim.2016.09.002

subject

Has Abstract

pub_date

2016-11-01 00:00:00

pages

30-33

eissn

0966-3274

issn

1878-5492

pii

S0966-3274(16)30055-7

journal_volume

39

pub_type

杂志文章
  • Free light chain and intact immunoglobulin abnormalities in heart transplant recipients: Two year follow-up timelines and clinical correlations.

    abstract:OBJECTIVES:To assess the timelines of serum free light chain (sFLC) concentrations and the kappa/lambda light chain (K/L) ratio in heart transplant (HTX) recipients. To analyze the performance of serum protein electrophoresis (SPE), serum immunofixation (sIFE) and sFLC measurements for gammopathy detection following a ...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2017.01.003

    authors: Sečník P Jr,Lavríková P,Hošková L,Malíková P,Jabor A,Franeková J

    更新日期:2017-03-01 00:00:00

  • Downregulation of Janus kinase 3 expression by small interfering RNA in rat composite tissue allotransplantation.

    abstract::RNA interference (RNAi) has recently emerged as an efficient method to silence gene expression in mammalian cells by transfection of small interfering RNAs (siRNAs). The Janus kinase 3 (JAK3) is also pertinent to the development of a new immuno-suppressant. This study aimed to inhibit JAK3 expression using RNAi to det...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2009.02.004

    authors: Chang KP,Lai CH,Huang SH,Tai HT,Chang LL,Lin SD,Hwang SL,Lai CS

    更新日期:2009-05-01 00:00:00

  • Impact of pretransplant exposure to allosensitization factors generating HLA antibodies in the Luminex era.

    abstract:AIM:To identify the frequency of exposure to sensitizing factors and evaluate the risk ascribable to each sensitizing factor generating HLAabs measured by Luminex. METHODS:This is a retrospective cohort study that included 502 transplanted patients and 51 patients on the waiting list for a deceased donor graft. Patien...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2016.08.003

    authors: Guichard-Romero A,Marino-Vazquez LA,Castelán N,López M,González-Tableros N,Arvizu A,De Santiago A,Alberú J,Morales-Buenrostro LE

    更新日期:2016-09-01 00:00:00

  • Immunosuppressant-induced cutaneous drug reactions in solid organ transplant recipients.

    abstract::Solid organ transplant recipients (SOTRs) are susceptible to various cutaneous side effects as a consequence of long-term immunosuppressive therapy. Skin cancers and infections are well-studied complications that can cause death and/or allograft rejection. Other cutaneous drug reactions, such as inflammatory manifesta...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2020.101355

    authors: Miotto IZ,Souza BCE,Tyring SK,de Oliveira WRP

    更新日期:2021-02-01 00:00:00

  • Transforming growth factor beta (TGFβ) plays a crucial role in prolonging allograft survival in an allodepletion ("pruning") skin transplant model.

    abstract::Adoptive cell therapies involving cell manipulation to achieve tolerance are increasingly being studied in animal models and in human trials. We have demonstrated that the specific removal of allo-stimulated dividing cells (or "pruning") promotes long-term allograft survival across a major MHC mismatch in transplant m...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2014.03.002

    authors: Watson D,Zhang GY,Hu M,Wang YM,Fletcher J,Sartor M,Alexander SI

    更新日期:2014-05-01 00:00:00

  • Effect of desensitization in solid organ transplant recipients depends on some cytokines genes polymorphism.

    abstract::Desensitization (DS) is widely used to decrease PRA in solid organs transplant candidates (TC). Various numbers of cycles of DS are required to reduce or eliminate donor specific antibodies (DSA). The goal of this study was to investigate if there was a correlation between polymorphism (PM) of some cytokine genes and ...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2009.03.002

    authors: Lobashevsky AL,Manwaring JE,Travis MM,Nord BL,Higgins NG,Serov YA,Arnoff TS,Hommel-Berrey GA,Goggins WC,Taber TE,Carter CB Sr,Smith DS,Wozniak TC,O'Donnell JA,Turrentine MW

    更新日期:2009-07-01 00:00:00

  • Transplantation of adipose tissue protects BB/OK rats from type 1 diabetes development.

    abstract::B(io) B(reedding)/O(ttawa) K(alsburg) rats spontaneously develop insulin-dependent type 1 diabetes. Days before BB/OK rats become diabetic, their body seems to be flabby which may be attributed to loss of subcutaneous fat. However, the rats are normoglycemic and manifest 3-4 days later. This observation prompted us to...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2011.01.003

    authors: Bahr J,Klöting N,Klöting I,Follak N

    更新日期:2011-05-01 00:00:00

  • Rebound effect of the allogenic T-cell response to donor and third-party lymphocytes after cyclosporine withdrawal in renal transplant recipients.

    abstract::Mixed lymphocyte reaction (MLR) assays were performed serially over 24 months in 19 first cadaver renal transplant recipients. Immunosuppression consisted of cyclosporine, methylprednisolone and azathioprine. Cyclosporine was withdrawn at 6 months postoperatively. The MLR reactivity gradually decreased over the first ...

    journal_title:Transplant immunology

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0966-3274(98)80016-6

    authors: Creemers P,Pascoe MD,Pontin AR,Kahn D

    更新日期:1998-12-01 00:00:00

  • Impact of rituximab on the T-cell flow cytometric crossmatch.

    abstract::Rituximab is frequently used in the setting of ABO-incompatible renal transplants, and highly sensitized patients. Its interference with B-cell flow cytometric crossmatch (B-FCXM) is well known. However, its effect on the T-cell flow cytometric crossmatch (T-FCXM) has not been described. We aimed to evaluate the effec...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2020.101360

    authors: Doss SA,Mittal S,Daniel D

    更新日期:2021-02-01 00:00:00

  • The selective biomarker IL-8 identifies IFTA after kidney transplantation in blood cells.

    abstract::Cellular and antibody-mediated rejection processes and also interstitial fibrosis/tubular atrophy (IFTA) lead to allograft dysfunction and loss. The search for accurate, specific and non-invasive diagnostic tools is still ongoing and essential for successful treatment of renal transplanted patients. Molecular markers ...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2016.09.003

    authors: Matz M,Lorkowski C,Fabritius K,Wu K,Rudolph B,Frischbutter S,Brakemeier S,Gaedeke J,Neumayer HH,Mashreghi MF,Budde K

    更新日期:2016-11-01 00:00:00

  • Toll-like 4 receptor (TLR4) expression on peripheral blood mononuclear cells in renal transplant recipients with pre-transplant chronic interstitial nephritis indicates patients at risk of graft deterioration.

    abstract::Data binding the expression of Toll-like 4 receptor (TLR4ex), transplanted kidney function, and the cause of pre-transplant end-stage renal disease are scarcely available. OBJECTIVE:To investigate the relationship between pre-transplant chronic interstitial nephritis (CIN), TLR4ex and transplanted kidney function. M...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2020.101319

    authors: Zmonarski SC,Banasik M,Golebiowski T,Madziarska K,Mazanowska O,Myszka M,Zmonarska J,Letachowicz K,Dawiskiba T,Krajewska M

    更新日期:2020-10-01 00:00:00

  • Requirement of B7-H1 in mesenchymal stem cells for immune tolerance to cardiac allografts in combination therapy with rapamycin.

    abstract:BACKGROUND:The potential of mesenchymal stem cells (MSCs) for immunosuppression has been tested in transplantation, but its mechanisms are not fully understood. This study investigated the role of MSC-expressing B7-H1 in the induction of immune tolerance to cardiac allografts by the combination therapy of MSCs and rapa...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2014.06.005

    authors: Wang H,Qi F,Dai X,Tian W,Liu T,Han H,Zhang B,Li H,Zhang Z,Du C

    更新日期:2014-08-01 00:00:00

  • FTY720 treatment of kidney transplant patients: a differential effect on B cells, naïve T cells, memory T cells and NK cells.

    abstract::FTY720 alters lymphocyte recirculation and homing by interfering with S1P receptors on lymphocytes, possibly in combination with chemokine receptors, and induces a decrease in PBL counts. In fresh, whole blood samples of 14 kidney transplant patients, we analyzed by flow cytometry the effect of FTY on the number of NK...

    journal_title:Transplant immunology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.trim.2006.02.002

    authors: Vaessen LM,van Besouw NM,Mol WM,Ijzermans JN,Weimar W

    更新日期:2006-04-01 00:00:00

  • An alternative conditioning regimen for induction of specific skin graft tolerance across full major histocompatibility complex barriers.

    abstract::Previously, we developed a well-tolerated single-day protocol for induction of stable multilineage chimerism and permanent donor-specific tolerance across major histocompatibility complex (MHC) barriers, with preservation of the host's normal immune responses. In our murine model, recipient mice were treated with a si...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/s0966-3274(98)80039-7

    authors: de Vries-van der Zwan A,van der Pol MA,de Waal LP,Boog CJ

    更新日期:1998-09-01 00:00:00

  • Biomarkers for acute and chronic graft-versus-host disease in regulatory T cells.

    abstract::Despite improvements in the prevention and treatment of graft-versus-host disease (GvHD) this allogeneic immune response is still one of major complications following allogeneic stem cell transplantation (SCT). Identification of patients at risk for the development of acute and chronic GvHD would facilitate early inte...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2012.07.003

    authors: Ukena SN,Geffers R,Buchholz S,Stadler M,Franzke A

    更新日期:2012-12-01 00:00:00

  • T cell receptor (beta chain) transgenic mice have selective deficits in gamma delta T cell subpopulations.

    abstract::TCR-beta (T cell receptor-beta chain) transgenic mice have altered lymphocyte development. TCR-beta transgenic mice are hyporesponsive to alloantigens in vivo and are deficient in gamma delta T cells. In order to begin a study of the relationship between a deficiency of alloreactive gamma delta cells and the defective...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/0966-3274(94)90063-9

    authors: Rimm IJ,Fruman DA,Abhyankar S,Sakamoto H,Orme IM,Milstone D,Seidman JG,Ferrara JL

    更新日期:1994-09-01 00:00:00

  • Antibody response to HBV vaccination on dialysis does not correlate with the development of deNovo anti-HLA antibodies after renal transplantation.

    abstract:BACKGROUND:Response to Hepatitis B virus (HBV) vaccination can be diminished in some (50-80%) but not all dialysis patients. We hypothesized, that the response to vaccination on dialysis may correlate with the development of anti-HLA antibodies after renal transplantation and might therefore be a valuable parameter to ...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2017.04.003

    authors: Kauke T,Link M,Rentsch M,Stangl M,Guba M,Andrassy J,Werner J,Meiser B,Fischereder M,Habicht A

    更新日期:2017-06-01 00:00:00

  • Effects of recombinant thrombomodulin therapy and soluble human leukocyte antigen-G levels during hematopoietic stem cell transplantation.

    abstract:BACKGROUND:Conditioning chemotherapies for hematopoietic stem cell transplantation (HSCT), especially those that include total body irradiation, can result in serious complications such as graft-versus-host disease (GVHD). Human leukocyte antigen G (HLA-G) is a non-classical class I molecule with multiple immunoregulat...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2018.12.001

    authors: Nomura S,Ito T,Katayama Y,Ota S,Hayashi K,Fujita S,Satake A,Ishii K

    更新日期:2019-04-01 00:00:00

  • Strategies in analysis of the genetic component of multifactorial diseases; biostatistical aspects.

    abstract::Complex polygenic and multifactorial diseases remain a challenge for human geneticists. Here we aim to remind basic definitions of multifactorial diseases and the genetic related concepts underlying classical methods. Knowledge on pathophysiological process and the genetic information available conditions the design o...

    journal_title:Transplant immunology

    pub_type: 杂志文章,评审

    doi:10.1016/j.trim.2005.03.015

    authors: Barnetche T,Gourraud PA,Cambon-Thomsen A

    更新日期:2005-08-01 00:00:00

  • Effects of a calcineurin inhibitor, FK506, and a CCR5/CXCR3 antagonist, TAK-779, in a rat small intestinal transplantation model.

    abstract::The effects of FK506, and TAK-779, antagonists of CCR5 and CXCR3, were investigated using a rat intestinal transplantation model. Small intestines from DA rats were heterotopically transplanted into LEW rats. The recipients were treated with FK506 (1mg/kg/day, day 0-5) and TAK-779 (10mg/kg/day, day 0-10). Graft surviv...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2011.04.003

    authors: Takama Y,Miyagawa S,Yamamoto A,Firdawes S,Ueno T,Ihara Y,Kondo A,Matsunami K,Otsuka H,Fukuzawa M

    更新日期:2011-07-01 00:00:00

  • De novo alloreactive memory CD8+ T cells develop following allogeneic challenge when CNI immunosuppression is delayed.

    abstract::Allospecific memory T cells are a recognized threat to the maintenance of solid-organ transplants. Limited information exists regarding the development of alloreactive memory T cells when post-transplant immunosuppression is present. The clinical practice of delaying calcineurin inhibitor (CNI) initiation post-transpl...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2014.10.001

    authors: Hart-Matyas M,Gareau AJ,Hirsch GM,Lee TD

    更新日期:2015-01-01 00:00:00

  • Why statin therapy may increase the risk for posttransplantation squamous cell carcinoma.

    abstract::We suggest that surveillance for squamous cell cancer might be particularly useful for transplant patients receiving statin therapy. We recommend that development of non melanoma skin cancer should be specified as a secondary endpoint in future large endpoint statin trials, and suggest that in transplant patients the ...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2010.06.001

    authors: Mascitelli L,Pezzetta F,Goldstein MR

    更新日期:2010-08-01 00:00:00

  • Clinical utility of CD4+ function assessment (ViraCor-IBT ImmuKnow test) in lung recipients.

    abstract::The ImmuKnow assay measures cell-mediated immunity, quantifying ATP production from peripheral blood CD4+T-cells in solid-organ transplant patients who undergo immunosuppressive therapy. We aimed to measure functional immunity in lung transplant recipients and correlate Immuknow values with immunosuppression levels, p...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2016.04.001

    authors: Piloni D,Magni S,Oggionni T,Benazzo A,Stella G,Scudeller L,Morosini M,Cova E,Meloni F

    更新日期:2016-07-01 00:00:00

  • Impact of HLA polymorphisms among cadaveric donors on kidney graft allocation.

    abstract::This study provides data on HLA-A, -B, and -DRB1 frequencies among 861 end-stage renal disease (ESRD) patients from Croatia and estimates the benefit of the kidney exchange program by comparing HLA distribution and assessing HLA mismatches (MMs) within a group of ESRD patients who received kidney grafts from 707 cadav...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2020.101318

    authors: Grubic Z,Burek Kamenaric M,Kljajic J,Stingl Jankovic K,Maskalan M,Zunec R

    更新日期:2020-10-01 00:00:00

  • Current cellular immunological hurdles in pig-to-primate xenotransplantation.

    abstract::In this review, we summarize the work published over the last few years relative to cellular immunological hurdles encountered specifically in pig-to-primate xenotransplantation models. The works summarized here cover both the innate and adaptative cellular immune response as well as strategies to overcome them and co...

    journal_title:Transplant immunology

    pub_type: 杂志文章,评审

    doi:10.1016/j.trim.2008.10.006

    authors: Le Bas-Bernardet S,Blancho G

    更新日期:2009-06-01 00:00:00

  • Differential Th1 and Th2 cell regulation of murine cardiac allograft acceptance by blocking cell adhesion of ICAM-1/LFA-1 and VCAM-1/VLA-4.

    abstract::Administration of anti-intercellular adhesion molecule (ICAM)-1 monoclonal antibody (mAb) plus anti-lymphocyte function associated antigen (LFA)-1 mAb induces tolerance in murine cardiac transplantation, while anti-vascular cell adhesion molecule (VCAM)-1 mAb plus anti-very late antigen (VLA)-4 mAb administration prol...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/s0966-3274(99)80021-5

    authors: Suzuki J,Isobe M,Izawa A,Takahashi W,Yamazaki S,Okubo Y,Amano J,Sekiguchi M

    更新日期:1999-03-01 00:00:00

  • The role of CD40L in T cell-dependent nitric oxide production by murine macrophages.

    abstract::Upon activation, T cells express CD40L, a member of the TNF cytokine superfamily, which serves as a ligand for CD40 on antigen presenting cells, including dendritic cells, B cells, and macrophages. While initial studies on the function of CD40 focused its role in the regulation of B cell activation, more recent studie...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/s0966-3274(00)00026-5

    authors: Bingaman AW,Pearson TC,Larsen CP

    更新日期:2000-11-01 00:00:00

  • A novel MyD88 inhibitor attenuates allograft rejection after heterotopic tracheal transplantation in mice.

    abstract:BACKGROUND:After lung transplantation, the major complication limiting the long-term survival of allografts is obliterative bronchiolitis (OB), characterized by chronic rejection. Innate immune responses contribute to the development of OB. In this study, we used a murine heterotopic tracheal transplantation mouse mode...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/j.trim.2018.11.006

    authors: Yang M,Chen G,Zhang X,Ding Z,Miao Y,Yang Y,Chen ZK,Jiang F,Chang S,Zhou P

    更新日期:2019-04-01 00:00:00

  • Clinical significance of selective decline of donor-reactive IL-2-producing T lymphocytes after renal transplantation.

    abstract::Limiting dilution analysis technique was used to enumerate the circulating precursor frequency of donor and third-party-reactive helper T lymphocytes (HTLpf) in 28 renal allograft recipients before (pre-tx) and at three intervals (T1: 60-90 days, T2: 120-180 days, T3: 360-1620 days) after transplantation (post-tx). Tw...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/s0966-3274(97)80048-2

    authors: Beik AI,Higgins RM,Lam FT,Morris AG

    更新日期:1997-06-01 00:00:00

  • Evaluation of peripheral blood CD4 and CD8 lymphocyte subsets, CD69 expression and histologic rejection grade as diagnostic markers for the presence of cardiac allograft rejection.

    abstract::We investigated the dynamics of the CD4+ and CD8+ lymphocyte subsets, and the expression of activation markers in cardiac transplant recipients. We tested 132 peripheral blood samples from 62 cardiac transplant recipients using fluorescent staining and flow cytometry analysis. The results were correlated with histolog...

    journal_title:Transplant immunology

    pub_type: 杂志文章

    doi:10.1016/s0966-3274(02)00072-2

    authors: Creemers P,Brink J,Wainwright H,Moore K,Shephard E,Kahn D

    更新日期:2002-11-01 00:00:00