Abstract:
:Tick bites often go unnoticed, so specific reliable tests are needed to confirm them for prompt diagnosis and treatment of tick-borne diseases. One of the promising candidates for developing such a test is AV422, a tick saliva protein that has been conserved across tick genera. In this study, we demonstrate the potential of the AV422 homologue from Ixodes ricinus to be used for tick bite detection for both Prostriata and Metastriata. We expressed recombinant (r) I. ricinus (Ir) AV422 in E. coli and subjected it to Western blot analysis using rat antibodies to saliva proteins of both I. ricinus (Prostriata) and Dermacentor reticulatus (Metastriata) larvae. Our data demonstrate that rIrAV422 specifically bound to antibodies from sera of rats used for both I. ricinus and D. reticulatus larvae feeding, but not to antibodies from control serum, emphasizing its specificity since tick bites were the sole cause of sera reactivity.
journal_name
Ticks Tick Borne Disjournal_title
Ticks and tick-borne diseasesauthors
Mihaljica D,Marković D,Radulović Ž,Mulenga A,Ćakić S,Sukara R,Samardžić J,Tomanović Sdoi
10.1016/j.ttbdis.2017.01.001subject
Has Abstractpub_date
2017-03-01 00:00:00pages
391-395issue
3eissn
1877-959Xissn
1877-9603pii
S1877-959X(17)30009-2journal_volume
8pub_type
杂志文章abstract::Due to the availability of adequate habitats in urban environments, e.g. city parks and recreational green areas, ticks from such settings may also carry pathogens of veterinary and public health concern. Thus, tick-borne infections may readily be identified in companion animals residing in urbanised areas. To investi...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2012.08.005
更新日期:2013-02-01 00:00:00
abstract::Anaplasma phagocytophilum is an emerging zoonotic tick-borne pathogen affecting a wide range of mammals. Rodents are suspected to be natural reservoirs for this bacterium, but their role in the epidemiologic cycles affecting domestic animals and wild ungulates has not been demonstrated. This study aimed to improve our...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2016.05.005
更新日期:2016-07-01 00:00:00
abstract::The current need of identification of a new acaricidal agent which is acceptable to public as environmentally safe is a daring task. Use of herbal acaricides is such an alternative. Most of the herbal extracts or fractions are dissolved in polar or non-polar solvents or detergents before tested for acaricidal activity...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2011.04.001
更新日期:2011-09-01 00:00:00
abstract::Immature Ixodes scapularis infestation and Borrelia burgdorferi infection of wild small mammals were studied from June to October in 2007 and from May to October in 2008 at 71 study sites in a zone where I. scapularis populations and environmental Lyme disease risk are emerging in southwestern Quebec. Seasonal host-se...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2011.03.005
更新日期:2011-12-01 00:00:00
abstract::Babesiosis is an emerging tick-borne infection. We describe 2 hospitalized patients from the United States with spontaneous splenic rupture attributable to Babesia microti infection. The first patient was a 36-year-old previously healthy man with a low-grade splenic rupture not requiring surgical intervention. The sec...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2011.08.001
更新日期:2011-12-01 00:00:00
abstract::The seasonal risk to humans of picking up Ixodes ricinus ticks in different habitats at 3 recreational sites in the UK was assessed. A comprehensive range of vegetation types was sampled at 3-weekly intervals for 2 years, using standard blanket-dragging complemented by woollen leggings and square 'heel flags'. Ticks w...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2011.03.002
更新日期:2011-06-01 00:00:00
abstract::Surveillance indicates that tick-borne diseases are a common problem in the United States. Nevertheless, little is known regarding the experience or management practices of healthcare providers who treat these conditions. The purpose of the present study was to characterize the frequency of tick-borne diseases in clin...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2014.01.008
更新日期:2014-06-01 00:00:00
abstract::Kyasanur Forest disease virus (KFDV) and Alkhurma hemorrhagic fever virus (AHFV) are enveloped, positive-stranded RNA viruses of clinical importance with complex enzootic life cycles involving hematophagous ticks which feed on small and large mammals. Humans and monkeys are dead-end hosts for these viruses. Recent tre...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101381
更新日期:2020-05-01 00:00:00
abstract::Anaplasma marginale infections are responsible for widespread morbidity and mortality particularly in crossbred and exotic breeds of cattle in the tropics and subtropics. In the present study, a semi-nested PCR assay was utilized for the detection of A. marginale infection in carrier cattle from different areas of Pun...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2011.10.002
更新日期:2012-02-01 00:00:00
abstract::Lyme borreliosis (LB) is the most important human tick-borne disease, but Borrelia genospecies cause different clinical manifestations. Ticks of the genus Ixodes removed from humans between 2006 and 2012 were analysed for Borrelia burgdorferi sensu lato (sl) infections. The majority of ticks originated from the Greate...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2017.05.003
更新日期:2017-08-01 00:00:00
abstract::Anaplasma phagocytophilum is an intracellular rickettsial pathogen transmitted by Ixodes spp. ticks, which causes granulocytic anaplasmosis in humans, horses and dogs and tick-borne fever (TBF) in ruminants. In the United States, human granulocytic anaplasmosis (HGA) is highly prevalent while TBF has not been reported...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2015.07.001
更新日期:2015-09-01 00:00:00
abstract::In North America, different strains of the Lyme disease-causing bacterium Borrelia burgdorferi sensu stricto cluster into phylogenetic groups that are associated with different levels of pathogenicity and, for some, specific rodent reservoir hosts. Here we explore whether landscape connectivity, by impacting host disp...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2018.07.001
更新日期:2018-09-01 00:00:00
abstract::Brazilian spotted fever (BSF) is the deadliest rickettsiosis in the world. Although the epidemiology of the disease has been established in Brazil, there are still limited data available on distribution of tick vectors and tick species parasitizing humans in the country, particularly in Paraná State. The State of Para...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2020.101510
更新日期:2020-11-01 00:00:00
abstract::Animal production has a key role in global economic development and food security. Ticks, specifically Rhipicephalus microplus cause substantial economic and health impacts on more than eighty percent of the world cattle population. Though synthetic acaricides play a major role in tick management, their injudicious us...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2021.101655
更新日期:2021-01-19 00:00:00
abstract::A total of 7364 ticks belonging to 13 species was collected from 64 game animals (belonging to 11 species) and from 64 livestock animals (cattle and sheep) living in close vicinity at 6 localities in 3 South African Provinces (Free State, Mpumalanga, and Limpopo). The geographic distribution of all tick species was co...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2013.10.003
更新日期:2014-03-01 00:00:00
abstract::Understanding the mechanism of pathogen transmission is essential for the development of strategies to reduce arthropod-borne diseases. The pharmaco- and immunomodulatory properties of insect and acarine saliva play an essential role in the efficiency of pathogen transmission. The skin as the site where arthropod sali...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2018.12.005
更新日期:2019-02-01 00:00:00
abstract::The intra-erythrocytic apicomplexan Babesia microti is the predominant pathogen that causes human babesiosis, an infectious disease that occurs worldwide. B. microti relies on the antioxidant including thioredoxin system to maintain the redox balance during the erythrocytic stage. In the present study, the full-length...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2018.01.021
更新日期:2018-03-01 00:00:00
abstract::This study is the first report about the prevalence of tick-borne pathogens, as well as their (co-)infection rates, in the museum-archived I. ricinus female ticks collected in Moldova in 1960. A total of 16.7% (21/126) ticks was mono-infected. Borrelia burgdorferi sensu stricto was revealed as the most abundant specie...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2012.12.004
更新日期:2013-06-01 00:00:00
abstract::Due to the ongoing expansion of Ixodes scapularis (blacklegged tick) throughout the northeastern and midwestern United States, there is need to identify the role wildlife hosts play in the establishment and maintenance of tick populations. To quantify and synthesize the patterns of I. scapularis and Borrelia burgdorfe...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.ttbdis.2018.04.006
更新日期:2018-07-01 00:00:00
abstract::A marked increase in tick-borne encephalitis (TBE) incidence has been observed in Europe during the last 2 decades. Hypothetical causes include global climatic fluctuations, human-induced environmental changes, and socio-economic changes. These factors are thought to be disproportionately relevant in different geograp...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2010.05.003
更新日期:2010-09-01 00:00:00
abstract::The lone star tick, Amblyomma americanum (L.) (Acari: Ixodidae), is established in southeastern Nebraska yet the prevalence of tick-associated microorganisms is not known. An initial PCR-based analysis for Ehrlichia chaffeensis, Ehrlichia ewingii, and Borrelia infection in host-seeking adult ticks collected in southea...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2015.10.008
更新日期:2016-02-01 00:00:00
abstract::With the aim of finding quantitative phenotypic traits that can be used to discriminate the levels of resistance/susceptibility to Babesia bovis, we estimated the repeatability and correlation between the level of infection, determined by the number of copies of a fragment of the gene that encodes cytochrome B (NC mt-...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2016.11.008
更新日期:2017-03-01 00:00:00
abstract::Information on Anaplasma phagocytophilum in Brazil is very restricted. The aim of this study was to report clinical, parasitological, hematological and molecular evidence of a natural A. phagocytophilum infection of an urban Brazilian dog. The dog was an eight-month-old male French bulldog. Veterinary clinical examina...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2015.01.003
更新日期:2015-04-01 00:00:00
abstract::Lyme disease is the most commonly reported vector-borne illness in the United States. Since the institution of Nationally Notifiable surveillance efforts for Lyme disease in the United States in 1991, there has been a consistent increase in the number of reported cases. Thus, the need for targeted prevention strategie...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2015.12.003
更新日期:2016-03-01 00:00:00
abstract::Equine piroplasmosis is one of the most significant tick-borne disease of equids. The prevalence of this disease in donkeys of semi-arid Kenya remains largely unexplored. The primary objective of this study was to demonstrate the extent to which donkeys in Nuu division, Kenya have been exposed to the haemoprotozoans B...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2015.05.015
更新日期:2015-07-01 00:00:00
abstract::Attempts to eliminate Rhipicephalus microplus from Uruguay have been unsuccessful, and, currently, the country is divided into two areas: a tick-free area and a tick-infested area. In the tick-infested area, different farms face different situations. Some farms are in regions where, due to environmental conditions or ...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2019.04.009
更新日期:2019-06-01 00:00:00
abstract::Workers at veterinary clinics are exposed to zoonotic pathogens, which, though infrequently, can lead to serious consequences. The aim of the present study was to estimate the seroprevalence for rickettsial pathogens in veterinary clinic personnel in Ciudad Juárez, Chihuahua, Mexico. Voluntary participants included 10...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2018.10.012
更新日期:2019-02-01 00:00:00
abstract::North Asian tick-typhus (NATT), also known as Siberian tick typhus, is the main tick-borne rickettsiosis in Siberia, Russia. Recently, a fatal infection in a four-year-old girl with typical tick-borne rickettsiosis symptoms (fever, rash, eschar at the site of the tick bite, myalgia) and meningeal syndrome was register...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2019.101278
更新日期:2019-10-01 00:00:00
abstract::Acaricide resistance is one of the greatest threats towards the successful control of vector ticks worldwide. Communal farmers of Zimbabwe use amitraz as the most common acaricide with occasional usage of pyrethroids and organophosphates. As a strategy towards developing an effective acaricide resistance management sy...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2017.10.017
更新日期:2018-01-01 00:00:00
abstract::This study reports the results of a comparative test of identification of ticks occurring in Western Europe and Northern Africa. A total of 14 laboratories were voluntarily enrolled in the test. Each participant received between 22 and 25 specimens of adult and nymphal ticks of 11 species: Dermacentor marginatus, D. r...
journal_title:Ticks and tick-borne diseases
pub_type: 杂志文章
doi:10.1016/j.ttbdis.2017.03.001
更新日期:2017-06-01 00:00:00