Abstract:
:Objective. Role of dysfunction of the sphincter of Oddi (SO) in choledocholithiasis is controversial. This study was to evaluate SO motor activity in patients with common bile duct (CBD) stones in the Han population of China. Patients and Methods. In this study, 76 patients with CBD stones were enrolled in a single tertiary endoscopy center. Data of SO motor activities was prospectively evaluated by endoscopic manometry. Mean basal SO pressure, amplitude, and frequency were collected and analyzed. Results. The mean basal SO pressure, amplitude, and frequency were 52.7 ± 40.0 (1.60-171.1) mmHg, 39.9 ± 19.7 (14.9-115.5) mmHg, and 5.7 ± 3.2 (1.3-13.8)/min, respectively. The basal SO pressure was higher in patients with CBD stones < 10 mm in diameter than that in those with CBD stones larger than 10 mm in diameter (60.7 ± 41.0 mmHg versus 36.8 ± 29.4 mmHg, P = 0.043). There was no significant difference in the basal SO pressure, amplitude, and frequency when compared with the CBD diameter, CBD stone number, prior cholecystectomy, periampullary diverticula, and symptoms. Levels of alanine aminotransferase, aspartate transaminase, γ-glutamyl transpeptidase, and alkaline phosphatase showed no significant difference in patients with normal or elevated basal SO pressure. Conclusion. These results identify that, in Chinese Han population, abnormalities of SO motor activity are associated with CBD stones.
journal_name
Gastroenterol Res Practjournal_title
Gastroenterology research and practiceauthors
Feng Y,Zhang J,Jiao C,Zhu H,Cheng W,Xu S,Xiao B,Ni J,Chen Xdoi
10.1155/2017/9031438subject
Has Abstractpub_date
2017-01-01 00:00:00pages
9031438eissn
1687-6121issn
1687-630Xjournal_volume
2017pub_type
杂志文章abstract::We determined comparative efficacy of i-Scan for detection and diagnosis of gastric cancer. Ten patients diagnosed with early gastric cancer based on histopathological findings were analyzed. White light and i-Scan moving images recorded from these patients in twin mode were separated into white light and i-Scan. Twel...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/819395
更新日期:2014-01-01 00:00:00
abstract::Background. The role of endoglin in the Dukes B rectal cancer is still unexplored. The aim of this study was to examine the expression of endoglin (CD105) in resected rectal cancer and to evaluate the relationship between microvessels density (MVD), clinicopathological factors, and survival rates. Methods. The study i...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2015/504179
更新日期:2015-01-01 00:00:00
abstract::Background. No predictive or prognostic biomarker is available for patients with locally advanced rectal cancer (LARC) undergoing perioperative chemoradiotherapy (CRT). Members of the human epidermal growth factor receptor (HER) family of receptor tyrosine kinases EGFR (HER1, ERBB1), HER2 (ERBB2), HER3 (ERBB3), and HE...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/3481578
更新日期:2016-01-01 00:00:00
abstract::Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a high rate of mortality and poor prognosis. Numerous studies have proved that microRNA (miRNA) may play a vital role in a wide range of malignancies, including PDAC, and dysregulated miRNAs, including circulating miRNAs, are associated with PDAC...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2014/386561
更新日期:2014-01-01 00:00:00
abstract::The rapid rise of obesity and type 2 diabetes poses a global threat to healthcare and is a major cause of mortality and morbidity. Bariatric surgery has revolutionised the treatment of both these conditions but is invasive and associated with an increased risk of complications. The EndoBarrier is a device placed endos...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2018/7823182
更新日期:2018-07-26 00:00:00
abstract::Endoscopic retrograde cholangiopancreatography (ERCP) can fail in 3-10% of the cases even in experienced hands. Although percutaneous transhepatic cholangiography (PTC) and surgery are the traditional alternatives, there are morbidity and mortality associated with both. In this paper, we have discussed the efficacy an...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2013/869214
更新日期:2013-01-01 00:00:00
abstract::Purpose. Radical surgical resection with adjuvant chemotherapy or chemo-radiotherapy is the most effective treatment for pancreatic ductal adenocarcinoma (PDAC). However, relatively few studies investigate the prognostic significance of biological markers in PDAC. This study aims to look into the expressions of viment...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/9207616
更新日期:2017-01-01 00:00:00
abstract:Aims:To evaluate the impact of body mass index (BMI) on the surgical outcome of laparoscopic total mesorectal excision (laTME) for locally advanced rectal cancer (LARC, clinically staged as UICC stage II/III) after neoadjuvant chemoradiotherapy (nCRT). Methods:312 LARC patients undergoing laTME after nCRT were divided...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/1509140
更新日期:2017-01-01 00:00:00
abstract::Purpose. Endoscopic ultrasound (EUS) permits the detailed visualization of clinically significant features of portal hypertension; however, it is an invasive procedure that is not widely available. The aim of this cross-sectional study was to determine whether a correlation exists between the features of portal hypert...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/395345
更新日期:2012-01-01 00:00:00
abstract:Background and Aims:Endoscopic papillary large balloon dilation (EPLBD) alone is an alternative to endoscopic sphincterotomy (EST) for treatment of common bile duct (CBD) stones. However, limited data exists regarding comparison of the long-term outcomes for these techniques. In this study, we compared the long-term ou...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/6430701
更新日期:2018-07-02 00:00:00
abstract::Background. Surgical treatment of hydatid liver disease (HLD) is divided into conservative and radical procedures. While conservative techniques are easier and faster to perform, there is an emerging need to reduce their morbidity and recurrence rates. Our aim was to present and evaluate the efficiency and safety of t...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2016/1078653
更新日期:2016-01-01 00:00:00
abstract::Background. The problems of fungal infections in edentulous have been discussed in literature. Findings show that oral mycosis has an influence on the mycosis of oesophageal mucosa. Based on this we started to follow from 2007 in patients who wear dentures mycological examination, to evaluate changes of yeasts numbers...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/951572
更新日期:2012-01-01 00:00:00
abstract::The aim of this study was to use functional magnetic resonance imaging (BOLD-fMRI) to investigate the activated region associated with visceral pain in the brains of infant rats in a model of IBS. Sixteen newborn rats were randomized into an IBS model group and a control group. Those in the IBS group were separated fr...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/473846
更新日期:2014-01-01 00:00:00
abstract::Hepatocellular carcinoma (HCC) ranks second amongst all causes of cancer deaths globally. It is on a rise in Pakistan and might represent the most common cancer in adult males. Pakistan contributes significantly to global burden of hepatitis C, which is a known risk factor for HCC, and has one of the highest prevalenc...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2016/5942306
更新日期:2016-01-01 00:00:00
abstract::Chronic gastritis is an inflammation of the gastric mucosa and has multiple etiologies. Here we discuss the pathological alterations induced by Helicobacter pylori (HP) leading to chronic gastritis and the epigenetic bases underlying these changes. We review the histology of the normal gastric mucosa and overview the ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2013/393015
更新日期:2013-01-01 00:00:00
abstract:BACKGROUNDS:Magnifying endoscopy with blue laser imaging (ME-BLI) for diagnosis of early gastric cancer (EGC) is as effective as magnifying endoscopy with narrow-band imaging (ME-NBI). However, there are different EGCs in microstructure visualization between ME-BLI and ME-NBI. This study aimed to clarify the pathologic...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/8303046
更新日期:2017-01-01 00:00:00
abstract::Caustic esophageal stricture (CES) in children still occurs frequently in developing countries. We aimed to evaluate the long-term outcomes of endoscopic balloon dilatation (EBD) in treating CES in children and the influencing factors associated with outcome. We retrospectively reviewed the data of all patients who ha...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/8352756
更新日期:2018-08-08 00:00:00
abstract::Objective. Here, we aim to investigate the microRNA (miR) profiling in human gastric cancer (GC). Methods. Tumoral and matched peritumoral gastric specimens were collected from 12 GC patients who underwent routine surgery. A high-throughput miR sequencing method was applied to detect the aberrantly expressed miRs in a...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/1526981
更新日期:2017-01-01 00:00:00
abstract::Aims. To compare the surgical and oncological outcomes of rectal mucinous adenocarcinomas treated with neoadjuvant chemoradiotherapy versus surgery alone. Methods. A total of 167 locally advanced rectal mucinous adenocarcinoma patients treated with neoadjuvant chemoradiotherapy and surgery alone between 2008 and 2014 ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/5715219
更新日期:2017-01-01 00:00:00
abstract::Introduction. Preoperative malnutrition is a major risk factor for increased postoperative morbidity and mortality. Definition and diagnosis of malnutrition and its treatment is still subject for controversy. Furthermore, practical implementation of nutrition-related guidelines is unknown. Methods. A review of the ava...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2011/739347
更新日期:2011-01-01 00:00:00
abstract::Background. Fat affects gastric emptying (GE). 5-Hydroxythryptophan (5-HTP) is involved in central and peripheral satiety mechanisms. Influence of 5-HTP in addition to saturated or monounsaturated fatty acids (FA) on GE and hormone release was investigated. Subjects/Methods. 24 healthy individuals (12f : 12m, 22-29 ye...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/424503
更新日期:2014-01-01 00:00:00
abstract::Perioperative chemotherapy improves overall survival in patients with oesophagogastric adenocarcinoma (OAC) and locoregional disease. The mainstay of perioperative chemotherapy in these patients is a platinum/fluoropyrimidine combination. The phase III FLOT4 trial has shown that the FLOT triplet regimen (oxaliplatin, ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2017/5651903
更新日期:2017-01-01 00:00:00
abstract::Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) have been established as treatment options for patients with peritoneal metastases or peritoneal mesothelioma. However, this novel treatment strategy remains associated with a large percentage of local-regional treatment failures. These ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/752643
更新日期:2012-01-01 00:00:00
abstract::Background. Since the incidence of adenocarcinoma of the oesophagus is rising, the prognosis is poor, and surveillance programs are expensive and mostly cost ineffective, there is a need to increase the knowledge of risk factors in Barrett's oesophagus and oesophageal cancer in order to be able to give attention to me...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/408470
更新日期:2014-01-01 00:00:00
abstract::Introduction. Neoadjuvant chemoradiotherapy and total mesorectal excision are considered the standard treatment for locally advanced rectal cancer. Various studies have reported pathological downstaging and a complete pathological response rate of 15%-27% following neoadjuvant chemoradiotherapy which has translated in...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2014/867841
更新日期:2014-01-01 00:00:00
abstract:Background and Aim:As part of the EC-IBD prospective inception cohort study, we had unique opportunity to follow up our patients since diagnosis in the early 1990s. Patients and Methods:All patients from the greater Dublin area (n = 192) were followed up from inception between 1991 and 1993 until the 30 September 2009...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/4946068
更新日期:2017-01-01 00:00:00
abstract:Aim:To evaluate the prevalence and risk factors of H. pylori infection in the pediatric and adult population seen at a public hospital in São José do Rio Preto, SP, Brazil. Methods:This is a retrospective study that evaluated 2406 medical records of children, adolescents, and adults with dyspeptic symptoms who underwe...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2018/8454125
更新日期:2018-09-04 00:00:00
abstract::Background and Aim. EUS-guided intervention (EGI) for biliary therapy has been increasingly used in recent years. This report aims to describe the spectrum and experience of EUS-guided interventions in biliary diseases in a single-tertiary center. Methods. All patients with EGI were analyzed retrospectively by retriev...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2012/680753
更新日期:2012-01-01 00:00:00
abstract::Epstein-Barr virus (EBV) is an important DNA virus which establishes latent infection in human malignancies. Expression of EBV-encoded genes in the associated tumors is strongly modulated by promoter CpG methylation of EBV genome. This study aimed to explore the methylation status of the promoters of EBV BamHI-A right...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章
doi:10.1155/2017/3804146
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Preoperative chemoradiotherapy is the standard treatment for patients with locally advanced rectal cancer, although tumor responses vary widely; some patients may achieve a pathologic complete response rate (pCR) after chemoradiotherapy. Controversy exists with regard to the efficacy of different preoperativ...
journal_title:Gastroenterology research and practice
pub_type: 杂志文章,评审
doi:10.1155/2017/1373092
更新日期:2017-01-01 00:00:00