Abstract：
:Neuropeptide Y (NPY) is widely distributed throughout the central nervous system and in several sympathetically innervated tissues, including the kidney. Although many central and peripheral acting endogenous compounds alter renal function, the role of NPY is unknown. Accordingly, we examined the effects of intracerebroventricular (ICV) or intrarenal administration of NPY on sodium and water excretion in the barbiturate anesthetized rat. Sprague-Dawley rats were uninephrectomized 10 days prior to testing and, in rats undergoing ICV administration, cannulae were implanted 3 days prior to testing. For testing, rats were anesthetized (Nembutal) and the jugular vein, renal artery and ureter catheterized. The results showed that the intrarenal infusion of NPY at 1 microgram/kg/min increased sodium and water excretion relative to the saline control group without altering blood pressure or creatinine clearance. Similarly, ICV administration of NPY at 10 micrograms in a 5 microliters volume increased the excretion of sodium and water without altering blood pressure as compared to the artificial CSF group. These findings suggest that both central and peripheral NPY may contribute to the regulation of sodium and water excretion in the rat.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Smyth DD,Wilson JR,Seidlitz E,Thom SLdoi
10.1016/0031-9384(89)90311-9subject
Has Abstractpub_date
1989-07-01 00:00:00pages
9-11issue
1eissn
0031-9384issn
1873-507Xpii
0031-9384(89)90311-9journal_volume
46pub_type
杂志文章abstract：:Oxidative damage is one of the hallmarks of the aging process. The current study evaluated effects of two proprietary antioxidant-based ingredients, rosemary extract and spearmint extract containing carnosic acid and rosmarinic acid, respectively, on learning and memory in the SAMP8 mouse model of accelerated aging. T...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.08.013
更新日期：2016-10-15 00:00:00
abstract：:The possibility of socially stressing the dominant/aggressive member of a pair of male mice is tested. Male mice (NMRI outbreed strain) were housed in pairs to assess dominant and subordinate roles by agonistic interactions and urine-marking test. Social stress for dominant males consisted in 30 min/day of exposure to...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(01)00460-7
更新日期：2001-06-01 00:00:00
abstract：:This study was designed to determine the differences between young and elderly people on the perceived intensity and pleasantness of sucrose in foods, in relation to their food intake. First, a group of 35 young subjects (mean age: 22 +/- 2 years) and 29 elderly subjects (mean age: 79 +/- 6 years) judged the intensity...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(96)00306-x
更新日期：1996-12-01 00:00:00
abstract：:For male guinea pigs, the social rearing conditions are crucial for the course of social interactions and endocrine stress responses in later life. While colony-reared males adjust easily to new social situations, high levels of aggression and extreme endocrine responses are found in males that were raised in pairs [P...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(03)00228-2
更新日期：2003-10-01 00:00:00
abstract：:Chronic stress during adolescence is related to increased prevalence of anxiety disorders and alcohol use disorders in humans. This phenotype has been consistently recapitulated in animal models with male subjects, but models using female subjects are fewer. The aim of these studies was to test the hypothesis that chr...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.02.010
更新日期：2017-05-01 00:00:00
abstract：:Taste sensitivity and responsivity, two-tastant and taste-mixture discrimination performance, and taste preferences were examined prior to and after the selective desalivation of 48 male Long-Evans rats. Altered preference behavior was observed in rats after removal of the major salivary glands, as well as after remov...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(90)90200-n
更新日期：1990-11-01 00:00:00
abstract：:Two groups of beagles, accustomed to spacious group housing, were subjected to social and spatial restriction and studied for manifestations of chronic stress with a time interval of 7 weeks between the groups. The change from outside group housing (the control period) to individual housing in small indoor kennels res...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(98)00290-x
更新日期：1999-04-01 00:00:00
abstract：:The renin angiotensin system (RAS; most well-known for its critical roles in the regulation of cardiovascular function and hydromineral balance) has regained the spotlight for its potential roles in various aspects of the metabolic syndrome. It may serve as a causal link among obesity and several co-morbidities. Drugs...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2010.03.018
更新日期：2010-07-14 00:00:00
abstract：:Individual differences in open-field activity and emotionality (number of defecations and urinations), voluntary wheel running, voluntary and forced maximal sprint running speed on a photocell-timed racetrack, swimming endurance, and maximal oxygen consumption (VO2max) were studied in 35 random bred male ICR mice. Wit...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90438-8
更新日期：1992-07-01 00:00:00
abstract：:Mixtures of compounds can often be tasted even when all of their components are too weak to be tasted separately. Such mixtures are said to be integrative. Integration was demonstrated by mixing compounds in concentrations proportional to their separate detection thresholds and then measuring the detection threshold o...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(97)00270-9
更新日期：1997-11-01 00:00:00
abstract：:Monogenic non-syndromic obesity is characterized by severe early-onset obesity with abnormal eating behaviour and endocrine disorders. Genes contributing to these rare forms of obesity are mainly located in the leptin/melanocortin pathway, with typically an autosomal additive inheritance of obesity. The normal functio...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.113134
更新日期：2020-12-01 00:00:00
abstract：:The aim of this work was to study the evolution of rat food choice in relation to their age and metabolic parameters. Eighty Wistar rats were studied from birth to 13 weeks of age. At weaning, six litters were fed on a macronutrient self-selecting diet and four on a standard diet. In self-selecting males, protein inta...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(02)00676-5
更新日期：2002-05-01 00:00:00
abstract：:Cocoa flavanols (CF) influence physiological processes in ways that suggest their consumption may improve aspects of neural function, and previous studies have found positive influences of CF on cognitive performance. In this preliminary study we investigated whether visual, as well as cognitive, function is influence...
journal_title：Physiology & behavior
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.physbeh.2011.02.013
更新日期：2011-06-01 00:00:00
abstract：:The sense of taste uses a variety of discrete receptor mechanisms to identify nutrients and toxins. Information from receptors is arrayed along a dimension of physiological welfare, which serves as the organizing principle of the taste system. This, in turn, drives central physiological and neurochemical processes tha...
journal_title：Physiology & behavior
pub_type： 杂志文章,评审
doi：10.1016/j.physbeh.2011.04.016
更新日期：2011-07-25 00:00:00
abstract：:Under permissive conditions, mice and hamsters exposed to a polyphasic light regime consisting of two light and two dark phases every 24 h (Light:Dark:Light:Dark; LDLD) can adopt a bifurcated entrainment pattern with roughly equal amounts of running wheel activity in each of the two nights. This rhythm "bifurcation" h...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.112625
更新日期：2019-10-15 00:00:00
abstract：:A simple, inexpensive device which controls the insertion, positioning and withdrawal of cortical undercutting microkinives is described. The device aids the "rolling" insertion of an L-shaped microknife which produces a minimum amount of overlying tissue damage while it holds the knife steady during undercutting and ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(83)80010-9
更新日期：1983-11-01 00:00:00
abstract：:The long-term consequences of a single social defeat on open field behaviour in rats were studied, with special emphasis on the time course of stress-induced changes. Animals were subjected to social defeat by placing them into the territory of an aggressive male conspecific for 1 h. After the defeat session experimen...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(95)02271-6
更新日期：1996-07-01 00:00:00
abstract：:EEG sleep recordings were performed in rats after administration of CCK-8. Mildly food-deprived rats were given IP CCK-8 (8 and 16 micrograms/kg body weight) and behavioural as well as EEG changes were examined. With 16 micrograms/kg of CCK-8, there was a significant increase of slow wave sleep in the 30 min of record...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(90)90242-v
更新日期：1990-12-01 00:00:00
abstract：:We developed and validated a method to measure steroid hormones with liquid chromatography-tandem mass spectrometry (LC-MS/MS) in faecal samples of white-faced capuchins. The method includes the measurement of adrenal and gonadal hormones such as cortisol, testosterone, estrone, progesterone and a number of their faec...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2011.09.004
更新日期：2012-01-18 00:00:00
abstract：:Siberian hamsters (Phodopus sungorus) increase food hoarding, but not food intake, after a fast. Because the physiological mechanisms underlying these changes in food hoarding are virtually unknown, we sought insight into these mechanisms by allowing hamsters to self-select their diet from food sources varying in macr...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(99)00167-5
更新日期：1999-12-01 00:00:00
abstract：:Exercise-related affective responses, particularly in-task, have been implicated as influencing behavioral maintenance. An extensive body of literature, primarily using aerobic modes in laboratory settings, has identified a relatively consistent inverse relationship between intensity and affect. This relationship is p...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.113261
更新日期：2021-03-01 00:00:00
abstract：:GPRC6A is an amino acid-sensing receptor highly expressed in the brain and in skeletal muscle. Although recent evidence suggests that genetically engineered GPRC6A receptor knockout (KO) mice are susceptible to develop subtle endocrine and metabolic disturbances, the underlying disruptions in energy metabolism are lar...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2013.05.015
更新日期：2013-06-13 00:00:00
abstract：BACKGROUND:Hydrogen sulfide (H2S) is the third gasotransmitter recently discovered after nitric oxide (NO) and carbon monoxide. Both NO and H2S are involved in multiple physiological functions. Whereas NO has been shown to vary with psychological stress, the influence of stress on H2S and the relationship between H2S a...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2017.05.023
更新日期：2017-10-01 00:00:00
abstract：:A binge drinking pattern of alcohol consumption has been shown to have an impact on brain structures that continue to develop into late adolescence. These same brain structures have been implicated in processing self-movement cues. The current study applies an array of existing and novel kinematic analysis techniques ...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2016.04.027
更新日期：2016-07-01 00:00:00
abstract：:Behavioural and hypothalamic-pituitary-adrenal (HPA) axis responses were investigated in farm mink (Mustela vison) selected for either confident or fearful behaviour for nine generations. Two groups of 2-year-old confident (n=12) and fearful (n=12) female mink were given the serotonin (5-HT) 1A receptor agonist buspir...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/s0031-9384(02)00964-2
更新日期：2003-02-01 00:00:00
abstract：:Endogenous opioid release has been linked to exercise. We investigated if opioid blockade following forced swimming, a common model of rodent exercise, influenced cerebral glucose metabolism in mice. PET scan was used to assess the uptake of Fludeoxyglucose (FDG-18), a marker of cerebral glucose metabolism in 19 regio...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.113199
更新日期：2021-01-01 00:00:00
abstract：:Our prior study showed that the basal blood pressure level and pressor response to peripheral angiotensin II of adult Sprague-Dawley rats were enhanced by perinatal exposure to a high NaCl diet. The purpose of the present study was to assess further the relationship between NaCl-sensitivity of blood pressure and perin...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(92)90164-w
更新日期：1992-03-01 00:00:00
abstract：:Two experiments were performed to examine the acute effects of thirst-inducing stimuli upon the intake of tap water and ethanol solutions by golden hamsters, a species which avidly consumes ethanol solutions. In Experiment 1, three groups of adult male hamsters (n = 6/group) were maintained on Purina chow and tap wate...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/0031-9384(90)90353-6
更新日期：1990-06-01 00:00:00
abstract：:The psychophysiological response due to stress of soldiers in actual combat operations have been determined by recent researchers, but there is a lack of knowledge about the most effective training methodologies to prepare these population for these new psychophysiological and tactical requirements. The aim of this st...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2019.01.009
更新日期：2019-03-15 00:00:00
abstract：:Animal behavior can be modulated by multiple interacting factors. In rodents such as rats, these factors include, among others, the female estrous cycle, exposure to a novel environment, and light. Here, we used the open field test to disassociate differences in behavior resulting from each of these factors by testing...
journal_title：Physiology & behavior
pub_type： 杂志文章
doi：10.1016/j.physbeh.2020.113203
更新日期：2021-01-01 00:00:00
