[Biologically active compounds from the aqueous extract of Urtica dioica].


:From the water extract of the roots of Urtica dioica (stinging nettle) a polysaccharide fraction was isolated which revealed activity in the carrageenan rat paw edema model and lymphocyte transformation test. Ion exchange chromatography and gel filtration of this fraction afforded 4 different polysaccharides, one of which reduced dose dependent hemolysis in the classical pathway of the complement test. The Urtica dioica lectin (UDA) was reisolated and found to stimulate the proliferation of human lymphocytes.


Planta Med


Planta medica


Wagner H,Willer F,Kreher B




Has Abstract


1989-10-01 00:00:00












  • Effects of propolis crude hydroalcoholic extract on chromosomal aberrations induced by doxorubicin in rats.

    abstract::Propolis has been reported to display a broad spectrum of biological activities such as anticancer, antioxidant, anti-inflammatory, antibiotic and antifungal properties, among others. There is great interest not only in the determination of the chemical composition of propolis but also in the understanding of the mech...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Tavares DC,Lira WM,Santini CB,Takahashi CS,Bastos JK

    更新日期:2007-12-01 00:00:00

  • Antifungal chromans inhibiting the mitochondrial respiratory chain of pea seeds and new xanthones from Calophyllum caledonicum.

    abstract::Two new xanthones, caledonixanthone M 1 and caloxanthone L 2, and one new acid, caledonic acid 6 were isolated from the hexane-soluble extract of the stem bark of Calophyllum caledonicum. In the course of this phytochemical study, seven other known compounds - calothwaitesixanthone, calozeyloxanthone, allanxanthone, i...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Hay AE,Guilet D,Morel C,Larcher G,Macherel D,Le Ray AM,Litaudon M,Richomme P

    更新日期:2003-12-01 00:00:00

  • Biosynthetic Studies on Acetosellin and Structure Elucidation of a New Acetosellin Derivative.

    abstract::Natural products from fungi, especially Ascomycota, play a major role in therapy and drug discovery. Fungal strains originating from marine habitats offer a new avenue for finding unusual molecular skeletons. Here, the marine-derived fungus Epicoccum nigrum (strain 749) was found to produce the azaphilonoid compounds ...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Hufendiek P,Stölben SSM,Kehraus S,Merten N,Harms H,Crüsemann M,Arslan I,Gütschow M,Schneider T,König GM

    更新日期:2017-08-01 00:00:00

  • Phthalides in the essential oil from roots of Levisticum officinale.

    abstract::The composition of the phthalide mixture of the essential oil from roots of Levisticum officinale Koch was investigated. The phthalide mixture was analyzed by combining separation methods - GLC, LSC and TLC - and subsequently using spectroscopic methods - IR, MS and NMR. E- and Z-butylidenephthalide, E- and Z-ligustil...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Gijbels MJ,Scheffer JJ,Baerheim Svendsen A

    更新日期:1982-04-01 00:00:00

  • Polyacetylenic compounds and butanol fraction from Bidens pilosa can modulate the differentiation of helper T cells and prevent autoimmune diabetes in non-obese diabetic mice.

    abstract::Compelling evidence suggests that infiltrating CD4+ type I helper T (Th1) cells in the pancreatic islets play a pivotal role in the progression of diabetes in non-obese diabetic (NOD) mice. We demonstrate in the present report that a butanol fraction of B. pilosa suppressed the development of diabetes, helped maintain...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Chang SL,Chang CL,Chiang YM,Hsieh RH,Tzeng CR,Wu TK,Sytwu HK,Shyur LF,Yang WC

    更新日期:2004-11-01 00:00:00

  • Cytotoxicity and p-glycoprotein modulating effects of quinolones and indoloquinazolines from the Chinese herb Evodia rutaecarpa.

    abstract::The antimycobacterial quinolones 1-methyl-2-undecyl-4-quinolone, dihydroevocarpine and evocarpine as well as the indoloquinazoline alkaloids rutaecarpine and evodiamine - all from the Chinese medicinal herb Evodia rutaecarpa - were tested in two in vitro assays, for cytotoxicity and interaction with p-glycoprotein (p-...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Adams M,Mahringer A,Kunert O,Fricker G,Efferth T,Bauer R

    更新日期:2007-12-01 00:00:00

  • Taxol biosynthesis: an update.

    abstract::The novel diterpenoid taxol (paclitaxel) is now well-established as a potent chemotherapeutic agent. Total synthesis of the drug is not commercially feasible and, in the foreseeable future, the supply of taxol and its synthetically useful progenitors must rely on biological methods of production. The first three steps...

    journal_title:Planta medica

    pub_type: 杂志文章,评审


    authors: Hezari M,Croteau R

    更新日期:1997-08-01 00:00:00

  • The alkaloid 4-methylaaptamine isolated from the sponge Aaptos aaptos impairs Herpes simplex virus type 1 penetration and immediate-early protein synthesis.

    abstract::We describe in this paper that the alkaloid 4-methylaaptamine, isolated from the marine sponge Aaptos aaptos, inhibited HSV-1 infection. We initially observed that 4-methylaaptamine inhibited HSV-1 replication in Vero cells in a dose-dependent manner with an EC50 value of 2.4 microM. Moreover, the concentration requir...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Souza TM,Abrantes JL,de A Epifanio R,Leite Fontes CF,Frugulhetti IC

    更新日期:2007-03-01 00:00:00

  • New triterpenoids from Kadsura heteroclita and their cytotoxic activity.

    abstract::Phytochemical investigations of the stem of Kadsura heteroclita (Roxb) Craib (Schizandraceae) resulted in the isolation and structure elucidation of six new triterpenoidal compounds named heteroclitalactones A-E (1-5) as well as heteroclic acid (6) and heteroclitalactone F (7), which was isolated for the first time fr...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Wang W,Liu J,Han J,Xu Z,Liu R,Liu P,Wang W,Ma X,Guan S,Guo D

    更新日期:2006-04-01 00:00:00

  • Inhibition of HIV-1 reverse transcriptase and HIV-1 replication by Calophyllum coumarins and xanthones.

    abstract::As part of our continuing study on the Calophyllum species, a number of coumarins, xanthones and chromene acids from different Calophyllum species of Sri Lanka were tested for inhibitory activity against the HIV-1 and its virally-encoded reverse transcriptase (RT). These compounds were found to be inactive in both the...

    journal_title:Planta medica

    pub_type: 信件


    authors: Dharmaratne HR,Tan GT,Marasinghe GP,Pezzuto JM

    更新日期:2002-01-01 00:00:00

  • Antibacterial properties of phenolic triterpenoids against Staphylococcus epidermidis.

    abstract::Two phenolic triterpenoids, pristimerol (30 µg/mL) and 8- EPI-6-deoxoblepharodol (20 µg/mL), obtained by catalytic reduction of pristimerin, exhibited bacteriostatic action against Staphylococcus epidermidis. This activity was not dependent on the inoculum size and the growth phase although it showed a stronger effect...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: López MR,de León L,Moujir L

    更新日期:2011-05-01 00:00:00

  • Smooth muscle relaxing compounds from Dodonaea viscosa.

    abstract::Bioassay-directed fractionation of the chloroform-methanol (1:1) extract of Dodonaea viscosa (L.) Jacq. (Sapindaceae) resulted in the isolation of four active spasmolytic principles: sakuranetin (1), 6-hydroxykaempferyl 3,7-dimethyl ether (2) hautrivaic acid (3), and ent-15, 16-epoxy-9 alpha H-labda-13(16)14-diene-3 b...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Rojas A,Cruz S,Ponce-Monter H,Mata R

    更新日期:1996-04-01 00:00:00

  • Salvia plebeia Extract Inhibits Xanthine Oxidase Activity In Vitro and Reduces Serum Uric Acid in an Animal Model of Hyperuricemia.

    abstract::Hyperuricemia is a clinical condition characterized by an elevated level of serum uric acid and is a key risk factor for the development of gout and metabolic disorders. The existing urate-lowering therapies are often impractical for certain patient populations, providing a rationale to explore new agents with improve...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Kim JK,Kim WJ,Hyun JM,Lee JS,Kwon JG,Seo C,Song MJ,Choi CW,Hong SS,Park K,Kim P,Sung H,Lee JK,Choi Y

    更新日期:2017-11-01 00:00:00

  • Unusual amino acids and monofluoroacetate from Dichapetalum michelsonii (Umutambasha), a toxic plant from Rwanda.

    abstract::In the course of our investigations on Umutambasha in order to identify its convulsant principles, small quantities of monofluoroacetate were observed in stem bark, leaves, and fruits of this plant newly identified as Dichapetalum michelsonii Hauman. Conclusive evidence for a monofluoroacetate presence came from its i...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Esters V,Karangwa C,Tits M,Francotte P,Pirotte B,Servais AC,Fillet M,Crommen J,Robbrecht E,Minet A,Grisar T,Angenot L,Frederich M

    更新日期:2013-03-01 00:00:00

  • New triterpenoids from the leaves of Cyclocarya paliurus.

    abstract::Six new triterpenoids including four new secodammarane triterpenoid glycosides (1-4), an epoxydammarane triterpenoid glycoside (5), and a new secodammarane triterpenoid (6) were isolated from the ethanolic extract of the leaves of Cyclocarya paliurus. The structures of these compounds were elucidated by spectroscopic ...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Li S,Cui B,Liu Q,Tang L,Yang Y,Jin X,Shen Z

    更新日期:2012-02-01 00:00:00

  • Antiedematogenic and free radical scavenging activity of swertiamarin isolated from Enicostemma axillare.

    abstract::Swertiamarin, a secoiridoid isolated from the ethyl acetate extract of Enicostemma axillare, was evaluated for antiedematogenic activity using carrageenan-, formalin-, and histamine-induced paw edema methods in rats. In the carrageenan-induced method, the percentages of edema inhibition obtained after 5 h induction we...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Vaijanathappa J,Badami S

    更新日期:2009-01-01 00:00:00

  • Ampelopsin prevents apoptosis induced by H2O2 in MT-4 lymphocytes.

    abstract::Human immunodeficiency virus (HIV) infection can result in oxidative stress through production of reactive oxygen species (ROS). Simultaneously, oxidative stress is able to activate the replication of virus and lead to the apoptosis of T lymphocytes which is the defense of the immune function. Ampelopsin, belonging to...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Ye J,Guan Y,Zeng S,Liu D

    更新日期:2008-02-01 00:00:00

  • Spectral characterisation and antiplasmodial activity of bisbenzylisoquinolines from Isolona ghesquiereina.

    abstract::From stem barks of Isolona guesquiereina three known bisbenzylisoquinolines were isolated and identified as (-)-curine, chondrofoline and isochondodendrine. Structures were established mainly on the basis of comparison of their physical and spectral data with published data for them and their methylated derivatives. C...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Mambu L,Martin MT,Razafimahefa D,Ramanitrahasimbola D,Rasoanaivo P,Frappier F

    更新日期:2000-08-01 00:00:00

  • Natural Phenolic Compounds and Derivatives as Potential Antimalarial Agents.

    abstract::Malaria is a parasitic disease endemic to tropical and subtropical regions responsible for hundreds of millions of clinical cases and hundreds of thousands of deaths yearly. Its agent, the Plasmodium sp., has a highly variable antigenicity, which accounts for the emergence and spread of resistance to all available tre...

    journal_title:Planta medica

    pub_type: 杂志文章,评审


    authors: Mamede L,Ledoux A,Jansen O,Frédérich M

    更新日期:2020-06-01 00:00:00

  • Assessment of the anti-HIV activity of a pine cone isolate.

    abstract::Characterization of an alkali-soluble isolate from Pinus nigra Arnold (Pinaceae) seed cones by thioacidolysis revealed a significant phenylpropanoid (i.c. lignin) component which may provide the observed anti-HIV-1 activity for this substance. ...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Eberhardt TL,Young RA

    更新日期:1996-02-01 00:00:00

  • Protective effect of (S)-bakuchiol from Psoralea corylifolia on rat liver injury in vitro and in vivo.

    abstract::The aim of this study was to investigate the protective effect of (S)-bakuchiol isolated from the seed of Psoralea corylifolia, on liver injury. Primary rat hepatocyte intoxication was induced by tert-butyl hydroperoxide (tBH), carbon tetrachloride (CCl4) or D-galactosamine (D-GalN). Liver injury was induced by either...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Park EJ,Zhao YZ,Kim YC,Sohn DH

    更新日期:2005-06-01 00:00:00

  • Cytotoxic aporphine alkaloids from Cassytha filiformis.

    abstract::Purification of a cytotoxic crude alkaloid extract of Cassytha filiformis led to the isolation of four known aporphine alkaloids: neolitsine, dicentrine, cassythine (= cassyfiline) and actinodaphnine. Their structures were determined by analysis of spectroscopic data. All isolated alkaloids were tested for their cytot...

    journal_title:Planta medica

    pub_type: 信件


    authors: Stévigny C,Block S,De Pauw-Gillet MC,de Hoffmann E,Llabrès G,Adjakidjé V,Quetin-Leclercq J

    更新日期:2002-11-01 00:00:00

  • Cycloartane triterpenoids from Cassia occidentalis.

    abstract::A phytochemical investigation of the whole plants of Cassia occidentalis led to the isolation of two new cycloartane triterpenoids, cycloccidentalic acids A and B (1 and 2), and five new related saponins, cycloccidentalisides I-V (3-7), together with sixteen known compounds. The structures of the isolated compounds we...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Li SF,Di YT,Luo RH,Zheng YT,Wang YH,Fang X,Zhang Y,Li L,He HP,Li SL,Hao XJ

    更新日期:2012-05-01 00:00:00

  • Metabolites of the mangrove fungus Xylaria sp. BL321 from the South China Sea.

    abstract::Two new lactones, 1 and 2, together with five known compounds, 3-7, were isolated from the marine mangrove fungus Xylaria sp. BL321. Their structures were determined by comprehensive analysis of their MS and NMR spectroscopic data. The absolute configurations of 1 and 2 were established on the basis of electronic circ...

    journal_title:Planta medica

    pub_type: 信件


    authors: Song YX,Wang J,Li SW,Cheng B,Li L,Chen B,Liu L,Lin YC,Gu YC

    更新日期:2012-01-01 00:00:00

  • The structure and the stereochemistry of atractyliretin.

    abstract::The nor-kaurane diterpene Atractyliretin was obtained by acid hydrolysis of Atractyloside, a toxic substance isolated from ATRACTYLIS GUMMIFERA L (Compositae). On the basis of spectral (IR, (1)H-NMR, (13)C-NMR and MS) analysis and chemical degradation its structure and stereochemistry was identified as 4. ...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Camarda L,Ceraulo L,Ferrugia M,Pascual C,Sprio V

    更新日期:1986-10-01 00:00:00

  • Cardioprotection and matrix metalloproteinase-9 regulation of salvianolic acids on myocardial infarction in rats.

    abstract::Acute myocardial infarction (AMI) remains the leading cause of mortality in the world. Early intervention using salvianolic acids (SA) can substantially improve clinical outcomes. However, in spite of the great achievements that have been made in elucidating the protective effects of SA on AMI, the effects of SA on th...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Jiang B,Wu W,Li M,Xu L,Sun K,Yang M,Guan S,Liu X,Guo DA

    更新日期:2009-10-01 00:00:00

  • Triterpenes and triterpenoid saponins from the leaves of Ilex kudincha.

    abstract::One new triterpene, kudinchalactone A (1), and four new triterpenoid saponins, ilekudinchosides A-D (2- 5), were isolated from the leaves of Ilex kudincha C. J. Tseng along with eight known triterpenoids. These new compounds were elucidated by spectroscopic methods including 1D and 2D NMR, HR-TOF-MS, and CD spectra. C...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Zuo WJ,Dai HF,Chen J,Chen HQ,Zhao YX,Mei WL,Li X,Wang JH

    更新日期:2011-11-01 00:00:00

  • Raspberry ketone increases both lipolysis and fatty acid oxidation in 3T3-L1 adipocytes.

    abstract::Raspberry ketone (RK) is a natural phenolic compound of the red raspberry. The dietary administration of RK to male mice has been reported to prevent high-fat diet-induced elevation in body weight and to increase lipolysis in white adipocytes. To elucidate a possible mechanism for the antiobesity action of RK, its eff...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Park KS

    更新日期:2010-10-01 00:00:00

  • Further lignans from Saururus chinensis.

    abstract::Three new sauchinone analogues, sauchinones B-D (1-3), together with sauchinone (4), were isolated from the aerial part of Saururus chinensis. Structures of the new compounds were determined by extensive spectroscopic data as well as X-ray analysis. Compounds 3 and 4 inhibited nitric oxide production in lipopolysaccha...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Gao X,He J,Wu XD,Peng LY,Dong LB,Deng X,Li Y,Cheng X,Zhao QS

    更新日期:2013-12-01 00:00:00

  • Simultaneous Quantification of Ursolic and Oleanolic Acids in Glechoma hederacea and Glechoma hirsuta by UPLC/MS/MS.

    abstract::The content of ursolic acid and oleanolic acid was determined in different plant parts of two Glechoma species, G. hederacea and G. hirsuta. To achieve optimal extraction conditions of ursolic acid and oleanolic acid from plant material, several methods including maceration, heat reflux, Soxhlet, and ultrasonic extrac...

    journal_title:Planta medica

    pub_type: 杂志文章


    authors: Grabowska K,Żmudzki P,Wróbel-Biedrawa D,Podolak I

    更新日期:2021-01-15 00:00:00