Abstract:
:From the water extract of the roots of Urtica dioica (stinging nettle) a polysaccharide fraction was isolated which revealed activity in the carrageenan rat paw edema model and lymphocyte transformation test. Ion exchange chromatography and gel filtration of this fraction afforded 4 different polysaccharides, one of which reduced dose dependent hemolysis in the classical pathway of the complement test. The Urtica dioica lectin (UDA) was reisolated and found to stimulate the proliferation of human lymphocytes.
journal_name
Planta Medjournal_title
Planta medicaauthors
Wagner H,Willer F,Kreher Bdoi
10.1055/s-2006-962062subject
Has Abstractpub_date
1989-10-01 00:00:00pages
452-4issue
5eissn
0032-0943issn
1439-0221journal_volume
55pub_type
杂志文章相关文献
PLANTA MEDICA文献大全abstract::25 Amaryllidaceae alkaloids belonging to different skeletal types were evaluated for their cytotoxic activity against one murine non-tumoral cell line (LMTK) and two human tumoral cell lines (Molt4 and HepG2) according to established protocols. Significant differences of activity related with the type of skeleton of t...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2006-958007
更新日期:1995-02-01 00:00:00
abstract::Bioassay-guided fractionation of the H(2)O extract of the seeds of Psoralea corylifolia furnished one hepatoprotective compound, bakuchiol (1), together with two moderately active compounds, bakuchicin (2) and psoralen (3), on tacrine-induced cytotoxicity in human liver-derived Hep G2 cells. The EC(50) values of compo...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-18347
更新日期:2001-11-01 00:00:00
abstract::Purification of a cytotoxic crude alkaloid extract of Cassytha filiformis led to the isolation of four known aporphine alkaloids: neolitsine, dicentrine, cassythine (= cassyfiline) and actinodaphnine. Their structures were determined by analysis of spectroscopic data. All isolated alkaloids were tested for their cytot...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-35651
更新日期:2002-11-01 00:00:00
abstract::A series of mainly marine derived natural products were tested for their activities against Mycobacterium tuberculosis and M. avium. Of the thirty-nine compounds tested fifteen demonstrated minimum inhibition concentrations (MICs) of 32 micrograms/ml or less, and eleven had MICs of 16 micrograms/ml or less. The most a...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2000-8534
更新日期:2000-05-01 00:00:00
abstract::From an extract of the whole plant of Ligularia virgaurea ssp. oligocephala, three new eremophilane sesquiterpene lactones, 10alpha-hydroxy-1-oxoeremophila-7(11),8(9)-dien-12,8-olide (1), 6alpha,10alpha-dihydroxy-1-oxoeremophila-7(11),8(9)-dien-12,8-olide (2), 6beta,10beta-dihydroxyeremophila-7(11),8(9)-dien-12,8-olid...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2004-818983
更新日期:2004-05-01 00:00:00
abstract::Mulberroside A, a major stilbene constituent of MORUS ALBA L. (Moraceae), displays significant antitussive and antiasthmatic effects in animals. As part of our ongoing research on its biotransformation in rats, mulberroside A was orally administered to rats, and the metabolites in the gastrointestinal contents and fec...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0029-1186160
更新日期:2010-03-01 00:00:00
abstract::The major alkaloids of PAPAVER TRINIIFOLIUM collected in two different parts of Anatolia have proved to be of the aporphine, morphinane and rhoeadine types. The two collections possessed different major alkaloids and the existence of chemical strains is indicated. In addition to the aporphine-(floripavidine), the morp...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-969808
更新日期:1983-09-01 00:00:00
abstract::Bioassay-guided fractionation of the hexanic root bark extract of Casearia sylvestris var. lingua led to the isolation of a new clerodane diterpene, whose structure was elucidated as rel-(2 S,5 R,6 R,8 S,9 S,10 R,18 S,19 R)-19-acetoxy-18,19-epoxy-6-hydroxy-18-butanoyloxy-2-(2-methylbutanoyloxy)cleroda-3,13(16), 14-tri...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2004-832655
更新日期:2004-11-01 00:00:00
abstract::Ginsenosides are the major principles of Panax ginseng C. A. Meyer (Araliaceae) used as a mild oriental folk medicine. In this report, we have examined the inhibitory potency of protopanaxadiol ginsenosides (PPDGs) such as Rb1, Rb2 and Rc, and their co-treatment effect with known tumor necrosis factor (TNF)-alpha anta...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2001-12005
更新日期:2001-04-01 00:00:00
abstract::Two indole alkaloids were isolated from the culture of Aspergillus fumigatus (strain No. CY018), an endophytic fungus harboring inside the elder leaf of Cynodon dactylon. These two chemicals were identified as fumigaclavine C and fumitremorgin C. In screening the bioactivity of these two indole alkaloids, their vasore...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-916235
更新日期:2006-04-01 00:00:00
abstract::The purpose of this study was to observe the protective effects of α-boswellic acids on hypoxia-induced pulmonary vascular structural remodeling in pulmonary arterial smooth muscle cells in a hypertensive rat model. Pulmonary arterial smooth muscle cells were cultured and then randomly divided into four groups: normox...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0042-109069
更新日期:2017-01-01 00:00:00
abstract::A method was developed to distinguish Vaccinium species based on leaf extracts using nuclear magnetic resonance spectroscopy. Reference spectra were measured on leaf extracts from several species, including lowbush blueberry (Vaccinium angustifolium), oval leaf huckleberry (Vaccinium ovalifolium), and cranberry (Vacci...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0034-1368569
更新日期:2014-06-01 00:00:00
abstract::A simple and efficient method for the separation of the three phenolic diketones, curcumin 1, demethoxycurcumin 2, and bis-demethoxycurcumin 3, isolated from the rhizomes of Curcuma longa has been developed. The method is of general applicability for the separation of compounds containing acidic and chelating groups a...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2000-8533
更新日期:2000-05-01 00:00:00
abstract::Bioassay directed fractionation of the (1:1) chloroform-methanol extract of Gentiana spathacea H.B.K (Gentianaceae) led to the isolation of gentiopicroside (gentiopricrin) (1), the major spasmolytic component of the plant. Gentiopicroside inhibited, in a concentration-dependent manner, the spontaneous contractions of ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2000-9774
更新日期:2000-12-01 00:00:00
abstract::The structure of albifloranine 1, a new alkaloid of ibogane type from the stem bark of Tabernaemontana albiflora (M IQ.) Pull. (Apocynaceae) has been determined. A detailed (1)H NMR study of albifloranine 1, coronaridine 2 and heyneanine 3 is presented. ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-971678
更新日期:1981-01-01 00:00:00
abstract::Anti-sera against a complement-activating pectin (AR-2IIb), which was purified from the roots of Angelica acutiloba Kitagawa, were obtained by immunization of rabbits, and a polyclonal anti-AR-2IIb antibody of the IgG class was purified by affinity chromatography on AR-2IIb-immobilized Sepharose and Protein G-Sepharos...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-959524
更新日期:1994-10-01 00:00:00
abstract::To assess possible herb-drug interactions, rutaecarpine (an herbal ingredient of Evodia rutaecarpa; 25 mg/kg/day, p. o.), the ethanol extract of Evodia rutaecarpa (1 g/kg/day, p. o.), and an herbal preparation of Evodia rutaecarpa (Wu-Chu-Yu-Tang; 1 g/kg/day) were individually pretreated daily for three consecutive da...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2005-871270
更新日期:2005-07-01 00:00:00
abstract::Six new triterpenoid saponins, psychotrianosides A-F (1-6), and two known triterpenoid saponins, psychotrianoside G (7) and ardisianoside D (8), were isolated from Psychotria sp. Their structures were determined mainly by spectroscopic methods. The cytotoxic activities of 1-8 against five human cancer cell lines (MDA-...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0032-1328650
更新日期:2013-07-01 00:00:00
abstract::Medicinal herbs are increasingly used in the search for safe and efficient drug candidates for hepatitis C virus infection. In this study, we have investigated the anti-HCV effect of compounds from Mori Cortex Radicis. During a screening for extracts with anti-HCV affinity from medicinal plants (173 species), the meth...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-990249
更新日期:2007-11-01 00:00:00
abstract::The 80% and 70% acetone extracts from fruits and leaves of Crataegus sinaica Boiss (Rosaceae) and the ethyl acetate-, butanol-, and water-fractions obtained from these initial extracts as well as the isolated compounds, quercetin (1) (1), hyperoside (quercetin 3-O-galactoside) (2) (2), rutin (quercetin 3-O-rutinoside)...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957786
更新日期:1996-02-01 00:00:00
abstract::HPLC determinations of the aescin contents in calli and embryoids from leaf explants of AESCULUS HIPPOCASTANUM L. were carried out in order to determine whether it was possible to obtain aescin-forming proliferations IN VITRO. The results indicate that embryogenic calli and embryoids derived from them produce an amoun...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-960016
更新日期:1991-02-01 00:00:00
abstract::The ripe berries of Harrisonia abyssinica yielded two new prenylated acetophenones, namely 5-(ethan-1'''-one)-4,6-dihydroxy-7-(3'',3''-dimethylallyl)-2 S-(1' S-hydroxy-1',5'-dimethylhex-4'-enyl)-2,3-dihydrobenzofuran (1) and 5-(2'''-hydroxyethan-1'''-one)-4,6-dihydroxy-7-(3'',3''-dimethylallyl)-2 S-(1' S-hydroxy-1',5'...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-0031-1298143
更新日期:2012-03-01 00:00:00
abstract::Three steroidal saponins, including astrogorgiosides A (1) and B (2) bearing acetamido-glucose moieties, and astrogorgioside C (3) with a 19-nor and bearing an aromatized B ring steroid aglycone, together with a known major saponin dimorphoside A (4), were obtained from the gorgonian Astrogorgia dumbea collected near ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0042-106168
更新日期:2016-06-01 00:00:00
abstract::During activity-guided fractionations to screen for antineoplastic agents, further studies by means of preparative HPLC led to the isolation of four known furostanol saponins: protoneodioscin, protodioscin, protoneogracillin, protogracillin, along with their corresponding artifacts: methyl protoneodioscin, methyl prot...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2006-957636
更新日期:1997-04-01 00:00:00
abstract::Different oil-samples of Melissa officinalis L. were analysed by capillary GC/MS, using fused silica columns and E.I.-Mass-spectrometry. Comparing the observed mass-spectra with those of a spectral collection, 70 compounds of the oil were identified. Geranial, neral, 6-methyl-5-hepten-2-one, citronellal, geranyl-aceta...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-970028
更新日期:1982-10-01 00:00:00
abstract::Both borneol and menthol are bioactive substances derived from Chinese herbal medicines. In order to understand the pharmacokinetics of borneol and menthol in Qingyan drop pills, a rapid, sensitive, and simple gas chromatographic (GC) method with flame ionization detection (FID) was developed for the simultaneous dete...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1270998
更新日期:2011-09-01 00:00:00
abstract::Three new coumarin derivatives, compounds 1-3, three new furanocoumarins, compounds 4-6, and a novel dioxocane derivative, compound 7, were isolated from the fern Cyclosorus interruptus (Willd.) H. Itô. Based on spectrometric and spectroscopic analysis (FAB or El mass spectrometry as well as 1D and 2D NMR experiments)...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2000-9908
更新日期:2000-12-01 00:00:00
abstract::The roots of Cryptolepis sanguinolenta have been investigated for their chemical composition since 1931 but so far no studies on the leaves have been reported although they are used in traditional medicine in Guinea-Bissau. Two new alkaloids identified as cryptolepinoic acid (1) and methyl cryptolepinoate (2) and the ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2000-11106
更新日期:2000-02-01 00:00:00
abstract::The methanol extract of the defatted roots of Asparagus adscendens Roxb. yielded beta-sitosterol beta-D-glucoside, two new spirostanol glycosides (asparanin C and asparanin D) and two new furostanol glycosides (asparoside C and asparoside D). ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2007-970018
更新日期:1982-09-01 00:00:00
abstract::Kava (Piper methysticum) is an effective anxiolytic that has been withdrawn from various consumer markets in European countries due to concerns over its hepatotoxicity. It is plausible that the reported hepatotoxicity may be due in part to plant substitution, or an incorrect cultivar, or plant parts being used (such a...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-0030-1250290
更新日期:2011-01-01 00:00:00