Health State Utility Values for Age-Related Macular Degeneration: Review and Advice.

Abstract:

:Health state utility values are a major source of uncertainty in economic evaluations of interventions for age-related macular degeneration (AMD). This review identifies and critiques published utility values and methods for eliciting de novo utility values in AMD. We describe how utility values have been used in healthcare decision making and provide guidance on the choice of utility values for future economic evaluations for AMD. Literature was searched using PubMed, and health technology assessments (HTA) were searched using HTA agency websites to identify articles reporting utility values or approaches to derive utility values in AMD and articles applying utilities for use in healthcare decision making relating to treatments for AMD. A total of 70 studies qualified for data extraction, 22 of which were classified as containing utility values and/or elicitation methods, and 48 were classified as using utility values in decision making. A large number of studies have elicited utility values for AMD, although those applied to decision making have focused on a few of these. There is an appreciation of the challenges in the measurement and valuation of health states, with recent studies addressing challenges such as the insensitivity of generic health-related quality of life (HRQoL) questionnaires and utility in the worse-seeing eye. We would encourage careful consideration when choosing utility values in decision making and an explicit critique of their applicability to the decision problem.

authors

Butt T,Tufail A,Rubin G

doi

10.1007/s40258-016-0275-9

subject

Has Abstract

pub_date

2017-02-01 00:00:00

pages

23-32

issue

1

eissn

1175-5652

issn

1179-1896

pii

10.1007/s40258-016-0275-9

journal_volume

15

pub_type

杂志文章,评审
  • Stated preference methods in health care evaluation: an emerging methodological paradigm in health economics.

    abstract::One focus of health economics is the trade-off between limited resources and the (health) needs of a community. Cost-effectiveness analysis (CEA), while being one of the most accepted evaluation methodologies in health economics, does not account for many important costs and benefits of health care interventions. Some...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章,评审

    doi:

    authors: Bridges JF

    更新日期:2003-01-01 00:00:00

  • The impact of pharmaceutical innovation on premature mortality, cancer mortality, and hospitalization in Slovenia, 1997-2010.

    abstract:BACKGROUND:In Slovenia during the period 2000-2010, the number of years of potential life lost before the age of 70 years per 100,000 population under 70 years of age declined 25 %. OBJECTIVE:The aim of this study was to test the hypothesis that pharmaceutical innovation played a key role in reducing premature mortali...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/s40258-014-0144-3

    authors: Lichtenberg FR

    更新日期:2015-04-01 00:00:00

  • The impact of inclusion criteria in health economic assessments.

    abstract::The debate surrounding whether the findings of efficacy studies are applicable to real-world treatment situations is ongoing. The issue of lack of applicability due to a lack of clinical heterogeneity could be addressed by employing less restrictive inclusion criteria. Given that health economic assessments based on c...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.2165/11590150-000000000-00000

    authors: Richter A,Thieda P,Thaler K,Gartlehner G

    更新日期:2011-05-01 00:00:00

  • Effectiveness of National Pricing Policies for Patent-Protected Pharmaceuticals in the OECD: A Systematic Literature Review.

    abstract:OBJECTIVES:The aim of this review is to assess the current state of empirical research regarding the effectiveness of national pricing regulations of the patent-protected market for prescription pharmaceuticals. Effectiveness is understood to be the capacity of policies to have a desired impact on outcomes, such as hea...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/s40258-018-0437-z

    authors: Wettstein DJ,Boes S

    更新日期:2019-04-01 00:00:00

  • Evaluating the Cost Effectiveness of a Suicide Prevention Campaign Implemented in Ontario, Canada.

    abstract:BACKGROUND:Although suicide-prevention campaigns have been implemented in numerous countries, Canada has yet to implement a strategy nationally. This is the first study to examine the cost utility of the implementation of a multidimensional suicide-prevention program that combines several interventions over a 50-year t...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/s40258-019-00511-5

    authors: Lebenbaum M,Cheng J,de Oliveira C,Kurdyak P,Zaheer J,Hancock-Howard R,Coyte PC

    更新日期:2020-04-01 00:00:00

  • The use of research abstracts in formulary decision making by the Joint Oncology Drug Review of Canada.

    abstract:BACKGROUND AND OBJECTIVE:Opinions on the use of research abstracts in policy decision making are conflicting. We sought to evaluate the influence of research abstracts in guiding decisions of the Joint Oncology Drug Review of Canada (JODR), which conducts clinical and economic reviews of new cancer treatment drugs for ...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.2165/11530510-000000000-00000

    authors: Weizman AV,Griesman J,Bell CM

    更新日期:2010-01-01 00:00:00

  • Impact of cross-reference pricing on pharmaceutical prices: manufacturers' pricing strategies and price regulation.

    abstract:OBJECTIVE:Several EU countries are determining reimbursement prices of pharmaceuticals by cross-referencing prices of foreign countries. Our objective is to quantify the theoretical cross-border spill-over effects of cross-reference pricing schemes on pharmaceutical prices in the former EU-15 countries. METHODS:An ana...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.2165/00148365-200605040-00005

    authors: Stargardt T,Schreyögg J

    更新日期:2006-01-01 00:00:00

  • Peristeen Transanal Irrigation System to Manage Bowel Dysfunction: A NICE Medical Technology Guidance.

    abstract::The Peristeen transanal irrigation system is intended to allow people with bowel dysfunction to flush out the lower part of the bowel as part of their bowel management strategy. Peristeen was the subject of an evaluation by the National Institute for Health and Care Excellence, through its Medical Technologies Evaluat...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章,评审

    doi:10.1007/s40258-018-0447-x

    authors: Dale M,Morgan H,Carter K,White J,Carolan-Rees G

    更新日期:2019-02-01 00:00:00

  • Implementing Guidelines: The Cost and Clinical Impact of Anticoagulants in the UK Atrial Fibrillation Population.

    abstract:BACKGROUND:Updated treatment guidelines for atrial fibrillation (AF) have been released by the National Institute for Health and Care Excellence (NICE) in the UK, and highlight a current shortfall in the prescription of anticoagulants to patients with AF for stroke prevention. OBJECTIVE:To design a budget impact model...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/s40258-015-0180-7

    authors: Shields GE,Bates AE,Chapman AM

    更新日期:2015-10-01 00:00:00

  • Household Size and the Decision to Purchase Health Insurance in Cambodia: Results of a Discrete-Choice Experiment with Scale Adjustment.

    abstract:BACKGROUND:Community-based health insurance (CBHI) schemes have been introduced in low- and middle-income countries to increase health service utilization and provide financial protection from high healthcare expenditures. OBJECTIVE:We assess the impact of household size on decisions to enroll in CBHI and demonstrate ...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/s40258-016-0222-9

    authors: Ozawa S,Grewal S,Bridges JF

    更新日期:2016-04-01 00:00:00

  • SecurAcath for Securing Peripherally Inserted Central Catheters: A NICE Medical Technology Guidance.

    abstract::Central venous catheters are commonly used to deliver therapies and to monitor patients, and require securing at the point of percutaneous entry to avoid dislodgement. SecurAcath is a catheter securement device designed for central venous catheters. The National Institute for Health and Care Excellence, as a part of i...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章,评审

    doi:10.1007/s40258-018-0427-1

    authors: Macmillan T,Pennington M,Summers JA,Goddard K,Zala D,Herz N,Peacock JL,Keevil S,Chalkidou A

    更新日期:2018-12-01 00:00:00

  • Cost-effectiveness analyses of osteoarthritis oral therapies: a systematic review.

    abstract:BACKGROUND:Cost-effectiveness analyses (CEAs) have been performed for oral non-disease-altering osteoarthritis (OA) treatments for well over a decade. During that period the methods for performing these analyses have evolved as pharmacoeconomic methods have advanced, new treatments have been introduced, and the knowled...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章,评审

    doi:10.1007/s40258-013-0061-x

    authors: Wielage RC,Myers JA,Klein RW,Happich M

    更新日期:2013-12-01 00:00:00

  • Cost effectiveness of self-monitoring of blood glucose (SMBG) for patients with type 2 diabetes and not on insulin: impact of modelling assumptions on recent Canadian findings.

    abstract:BACKGROUND:Canadian patients, healthcare providers and payers share interest in assessing the value of self-monitoring of blood glucose (SMBG) for individuals with type 2 diabetes but not on insulin. Using the UKPDS (UK Prospective Diabetes Study) model, the Canadian Optimal Prescribing and Utilization Service (COMPUS)...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.2165/11594270-000000000-00000

    authors: Tunis SL

    更新日期:2011-11-01 00:00:00

  • Socioeconomic Disparities in Unmet Need for Student Mental Health Services in Higher Education.

    abstract:BACKGROUND:Mental health problems are highly prevalent among college students in many countries. However, evidence suggests that many at-risk students do not receive professional help. OBJECTIVE:We aimed to understand which students are most likely to have unmet need for mental health services. Given increasing and wi...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/s40258-019-00529-9

    authors: Cullinan J,Walsh S,Flannery D

    更新日期:2020-04-01 00:00:00

  • Cost Analysis of Tuberculosis Diagnosis in Cambodia with and without Xpert® MTB/RIF for People Living with HIV/AIDS and People with Presumptive Multidrug-resistant Tuberculosis.

    abstract:BACKGROUND:The Xpert® MTB/RIF (Xpert) test has been shown to be effective and cost-effective for diagnosing tuberculosis (TB) under conditions with high HIV prevalence and HIV-TB co-infection but less is known about Xpert's cost in low HIV prevalence settings. Cambodia, a country with low HIV prevalence (0.7%), high TB...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/s40258-018-0397-3

    authors: Pallas SW,Courey M,Hy C,Killam WP,Warren D,Moore B

    更新日期:2018-08-01 00:00:00

  • Mental health: A Particular Challenge Confronting Policy Makers and Economists.

    abstract::The first objective of this paper is to expound the particular challenge posed by the occurrence of inconsistency in the expression of preferences by mental health patients to both economists and policy makers. Since this difficulty cannot be resolved, the second aim of the paper is to identify agents who may be count...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/s40258-019-00479-2

    authors: Zweifel P

    更新日期:2020-04-01 00:00:00

  • U.S. and International In-Hospital Costs of Extracorporeal Membrane Oxygenation: a Systematic Review.

    abstract:CONTEXT:The in-hospital costs of extracorporeal membrane oxygenation (ECMO) have not been well established. OBJECTIVE:To evaluate the in-hospital costs of ECMO technology in both US and non-US settings for all patient types. DATA SOURCES:Systematic review of English-language articles, using the PubMed, Embase, Web of...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章,评审

    doi:10.1007/s40258-015-0170-9

    authors: Harvey MJ,Gaies MG,Prosser LA

    更新日期:2015-08-01 00:00:00

  • Financial risk of the biotech industry versus the pharmaceutical industry.

    abstract::The biotech industry now accounts for a substantial and growing proportion of total R&D spending on new medicines. However, compared with the pharmaceutical industry, the biotech industry is financially fragile. This article illustrates the financial fragility of the biotech and pharmaceutical industries in the US and...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/BF03256149

    authors: Golec J,Vernon JA

    更新日期:2009-01-01 00:00:00

  • Listening to the decision makers: sustainability of PBMA in Alberta.

    abstract:BACKGROUND:Decision makers within the Calgary Health Region adopted and applied programme budgeting and marginal analysis (PBMA) for priority-setting activity across major service portfolios within the Region. METHODS:Seventeen in-depth qualitative interviews were conducted with senior managers and clinicians to gain ...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.2165/00148365-200403030-00005

    authors: Mitton C,Patten S,Donaldson C

    更新日期:2004-01-01 00:00:00

  • Level of Evidence in Economic Evaluations of Left Atrial Appendage Closure Devices: A Systematic Review.

    abstract:OBJECTIVES:The objective of the present work was to assess the level of evidence in economic evaluations of percutaneous left atrial appendage closure devices, and to test the complementarity of three different tools for assessing the quality of economic evaluations. METHODS:We conducted a systematic review of article...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/s40258-018-0429-z

    authors: Nédellec E,Pineau J,Prognon P,Martelli N

    更新日期:2018-12-01 00:00:00

  • Organization and estimated patient-borne costs of oral anticoagulation therapy in Italy: results from a survey.

    abstract:BACKGROUND:The management of the large patient population in Italy receiving long-term oral anticoagulation therapy (OAT) poses organizational challenges that are traditionally approached with a centralized procedure, relying on hospital-based clinics and/or GPs. However, the availability of near-patient testing device...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.2165/11313890-000000000-00000

    authors: Pradelli L,Iannazzo S,Zaniolo O,Botrugno P

    更新日期:2010-01-01 00:00:00

  • Demand for outpatient healthcare: empirical findings from rural India.

    abstract:BACKGROUND:Price, income and health status are likely to affect the demand for healthcare in developing countries, and their quantitative effects are unclear in the literature. Some studies report that prices are not important determinants, while others conclude that prices are important determinants of the demand for ...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/BF03256160

    authors: Sarma S

    更新日期:2009-01-01 00:00:00

  • Measuring Efficiency of Health Systems of the Middle East and North Africa (MENA) Region Using Stochastic Frontier Analysis.

    abstract:OBJECTIVE:The main purpose of this study is to measure the technical efficiency of twenty health systems in the Middle East and North Africa (MENA) region to inform evidence-based health policy decisions. In addition, the effects of alternative stochastic frontier model specification on the empirical results are examin...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/s40258-016-0230-9

    authors: Hamidi S,Akinci F

    更新日期:2016-06-01 00:00:00

  • Curos™ Disinfection Caps for the Prevention of Infection When Using Needleless Connectors: A NICE Medical Technologies Guidance.

    abstract::Central line-associated bloodstream infections (CLABSIs) are primary, laboratory confirmed bloodstream infections in patients with a central line within 48 h of symptom onset. Catheter-related bloodstream infection (CRBSI) is a more specific term used when the cause of infection has been confirmed by catheter tip cult...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章,评审

    doi:10.1007/s40258-020-00602-8

    authors: O'Connell S,Dale M,Morgan H,Carter K,Carolan-Rees G

    更新日期:2020-08-05 00:00:00

  • The Cost and Outcome Effectiveness of Total Hip Replacement: Technique Choice and Volume-Output Effects Matter.

    abstract:BACKGROUND:Total hip replacement (THR) must be managed in a more sustainable manner. More cost-effective surgical techniques and the centralization/regionalization of services are two solutions. The former requires an assessment of newer minimally invasive and muscle-sparing surgical techniques. The latter necessitates...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/s40258-016-0260-3

    authors: Goldstein JP,Babikian GM,Rana AJ,Mackenzie JA,Millar A

    更新日期:2016-12-01 00:00:00

  • Costs to hospitals of acquiring and processing blood in the US: a survey of hospital-based blood banks and transfusion services.

    abstract:BACKGROUND:little is known about the economics of acquiring and processing the more than 14 million units of red blood cells used annually in the US. OBJECTIVE:to determine the average price paid by hospitals to suppliers for a unit of red blood cells and to identify cost variations by region and facility type and siz...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.2165/11530740-000000000-00000

    authors: Toner RW,Pizzi L,Leas B,Ballas SK,Quigley A,Goldfarb NI

    更新日期:2011-01-01 00:00:00

  • Costs and consequences of clopidogrel versus aspirin for secondary prevention of ischaemic events in (high-risk) atherosclerotic patients in Sweden: a lifetime model based on the CAPRIE trial and high-risk CAPRIE subpopulations.

    abstract:BACKGROUND:Antiplatelet therapy plays a central role in the prevention of atherothrombotic events. Both acetylsalicylic acid (aspirin) and clopidogrel have been shown to reduce the risk of recurrent cardiovascular events in various subgroups of patients with vascular disease. OBJECTIVE:To estimate the cost effectivene...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.2165/11535520-000000000-00000

    authors: Logman JF,Heeg BM,Herlitz J,van Hout BA

    更新日期:2010-01-01 00:00:00

  • Current and future economic burden of osteoporosis in New Zealand.

    abstract:BACKGROUND:Osteoporosis is recognized as a serious health condition in developed as well as developing countries. There are no accurate estimates of the extent of the burden of osteoporosis in New Zealand. The purpose of this study was to estimate the economic burden of osteoporosis in New Zealand using data from inter...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.2165/11531500-000000000-00000

    authors: Brown P,McNeill R,Leung W,Radwan E,Willingale J

    更新日期:2011-03-01 00:00:00

  • The impact of rural health care accessibility on cancer-related behaviors and outcomes.

    abstract:BACKGROUND:This research seeks to identify the relationship between economic factors related to the ability to receive and pay for health services and adverse cancer outcomes, as well as preventative screening and behavioral factors that influence the risk of cancer. We focus on the Northern High Plains region, where w...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/s40258-014-0099-4

    authors: Belasco EJ,Gong G,Pence B,Wilkes E

    更新日期:2014-08-01 00:00:00

  • Using Post-market Utilisation Analysis to Support Medicines Pricing Policy: An Australian Case Study of Aflibercept and Ranibizumab Use.

    abstract:OBJECTIVES:To describe how post-market utilisation analysis in Australia informs cost-effectiveness assessment and pricing decisions, using aflibercept and ranibizumab as case studies. METHODS:Pharmaceutical claims were used to identify initiators of aflibercept and ranibizumab in the year after aflibercept-listing (D...

    journal_title:Applied health economics and health policy

    pub_type: 杂志文章

    doi:10.1007/s40258-018-0440-4

    authors: Kemp-Casey A,Pratt N,Ramsay E,Roughead EE

    更新日期:2019-06-01 00:00:00