Plasminogen deficiency.

Abstract:

:Plasminogen plays an important role in fibrinolysis as well as wound healing, cell migration, tissue modeling and angiogenesis. Congenital plasminogen deficiency is a rare autosomal recessive disorder that leads to the development of thick, wood-like pseudomembranes on mucosal surfaces, mostly seen in conjunctivas named as ''ligneous conjunctivitis''. Local conjunctival use of fresh frozen plazma (FFP) in combination with other eye medications such as cyclosporin and artificial tear drops may relieve the symptoms. Topical treatment with plasminogen eye drops is the most promising treatment that is not yet available in Turkey.

journal_name

J Thromb Thrombolysis

authors

Celkan T

doi

10.1007/s11239-016-1416-6

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

132-138

issue

1

eissn

0929-5305

issn

1573-742X

pii

10.1007/s11239-016-1416-6

journal_volume

43

pub_type

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