Spinal pedicle screw planning using deformable atlas registration.

Abstract:

:Spinal screw placement is a challenging task due to small bone corridors and high risk of neurological or vascular complications, benefiting from precision guidance/navigation and quality assurance (QA). Implicit to both guidance and QA is the definition of a surgical plan-i.e. the desired trajectories and device selection for target vertebrae-conventionally requiring time-consuming manual annotations by a skilled surgeon. We propose automation of such planning by deriving the pedicle trajectory and device selection from a patient's preoperative CT or MRI. An atlas of vertebrae surfaces was created to provide the underlying basis for automatic planning-in this work, comprising 40 exemplary vertebrae at three levels of the spine (T7, T8, and L3). The atlas was enriched with ideal trajectory annotations for 60 pedicles in total. To define trajectories for a given patient, sparse deformation fields from the atlas surfaces to the input (CT or MR image) are applied on the annotated trajectories. Mean value coordinates are used to interpolate dense deformation fields. The pose of a straight trajectory is optimized by image-based registration to an accumulated volume of the deformed annotations. For evaluation, input deformation fields were created using coherent point drift (CPD) to perform a leave-one-out analysis over the atlas surfaces. CPD registration demonstrated surface error of 0.89  ±  0.10 mm (median  ±  interquartile range) for T7/T8 and 1.29  ±  0.15 mm for L3. At the pedicle center, registered trajectories deviated from the expert reference by 0.56  ±  0.63 mm (T7/T8) and 1.12  ±  0.67 mm (L3). The predicted maximum screw diameter differed by 0.45  ±  0.62 mm (T7/T8), and 1.26  ±  1.19 mm (L3). The automated planning method avoided screw collisions in all cases and demonstrated close agreement overall with expert reference plans, offering a potentially valuable tool in support of surgical guidance and QA.

journal_name

Phys Med Biol

authors

Goerres J,Uneri A,De Silva T,Ketcha M,Reaungamornrat S,Jacobson M,Vogt S,Kleinszig G,Osgood G,Wolinsky JP,Siewerdsen JH

doi

10.1088/1361-6560/aa5f42

subject

Has Abstract

pub_date

2017-04-07 00:00:00

pages

2871-2891

issue

7

eissn

0031-9155

issn

1361-6560

journal_volume

62

pub_type

杂志文章
  • Iterative reconstruction for dual energy CT with an average image-induced nonlocal means regularization.

    abstract::Reducing radiation dose in dual energy computed tomography (DECT) is highly desirable but it may lead to excessive noise in the filtered backprojection (FBP) reconstructed DECT images, which can inevitably increase the diagnostic uncertainty. To obtain clinically acceptable DECT images from low-mAs acquisitions, in th...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa7122

    authors: Zhang H,Zeng D,Lin J,Zhang H,Bian Z,Huang J,Gao Y,Zhang S,Zhang H,Feng Q,Liang Z,Chen W,Ma J

    更新日期:2017-07-07 00:00:00

  • SAR variation study from 300 to 5000 MHz for 15 voxel models including different postures.

    abstract::An extensive study on specific absorption rate (SAR) covering 720 simulations and 15 voxel models (18-105 kg) has been performed by applying the parallel finite-difference time-domain method. High-resolution whole-body models have been irradiated with plane waves from 300 MHz to 5 GHz by applying various incoming dire...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/4/017

    authors: Uusitupa T,Laakso I,Ilvonen S,Nikoskinen K

    更新日期:2010-02-21 00:00:00

  • Tumour oxygen dynamics measured simultaneously by near-infrared spectroscopy and 19F magnetic resonance imaging in rats.

    abstract::Simultaneous near-infrared spectroscopy (NIRS) and magnetic resonance imaging (MRI) were used to investigate the correlation between tumour vascular oxygenation and tissue oxygen tension dynamics in rat breast 13762NF tumours with respect to hyperoxic gas breathing. NIRS directly detected global variations in the oxyg...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/51/1/004

    authors: Xia M,Kodibagkar V,Liu H,Mason RP

    更新日期:2006-01-07 00:00:00

  • Optical studies of vaporization and stability of fluorescently labelled perfluorocarbon droplets.

    abstract::Droplets of liquid perfluorocarbon (PFC) are under study as the next generation of contrast agents for ultrasound (US). These droplets can be selectively vaporized into echogenic gas bubbles in situ by externally applied US, with numerous applications to diagnosis and therapy. However, little is known about the mechan...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/57/21/7205

    authors: Reznik N,Seo M,Williams R,Bolewska-Pedyczak E,Lee M,Matsuura N,Gariepy J,Foster FS,Burns PN

    更新日期:2012-11-07 00:00:00

  • Quenching-free fluorescence signal from plastic-fibres in proton dosimetry: understanding the influence of Čerenkov radiation.

    abstract::The origin of photons emitted in optical fibres under proton irradiation has been attributed to either entirely Čerenkov radiation or light consisting of fluorescence with a substantial amount of Čerenkov radiation. The source of the light emission is assessed in order to understand why the signal from optical fibres ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aaafad

    authors: Brage Christensen J,Almhagen E,Nyström H,Andersen CE

    更新日期:2018-03-09 00:00:00

  • Correlation between dosimetric effect and intrafraction motion during prostate treatments delivered with helical tomotherapy.

    abstract::The dosimetric impact of intrafraction prostate motion was investigated for helical tomotherapy treatments. Measured motion tracks were used to calculate the dosimetric impact on delivered target dose distributions. A dynamic dose calculation engine was developed to facilitate this evaluation. It was found that the D9...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/24/005

    authors: Langen KM,Lu W,Ngwa W,Willoughby TR,Chauhan B,Meeks SL,Kupelian PA,Olivera G

    更新日期:2008-12-21 00:00:00

  • Fundamental study on diffuse reflective optical tomography.

    abstract::We report a simulation study on diffuse reflective optical computed tomography, in which continuous-wave sources and detectors are placed on the plane surface of a semi-infinite body. We adopted a simple Tikhonov regularization in the inverse problem and demonstrated the feasibility of three-dimensional reconstruction...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/49/10/004

    authors: Endoh R,Suzuki A,Fujii M,Nakayama K

    更新日期:2004-05-21 00:00:00

  • Monitoring the irradiation field of 12C and 16O SOBP beams using positron emitters produced through projectile fragmentation reactions.

    abstract::In order to effectively utilize the prominent properties of heavy ions in radiotherapy, it is important to evaluate both the position of the field irradiated with incident ions and the absorbed dose distribution in a patient's body. One of the methods for this purpose is the utilization of the positron emitters produc...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/53/3/002

    authors: Inaniwa T,Kohno T,Tomitani T,Sato S

    更新日期:2008-02-07 00:00:00

  • Using mathematical morphology to determine left ventricular contours.

    abstract::The aim of this study is to investigate the use of mathematical morphology for the determination of left ventricular contours in scintigraphic images using multigated radionuclide angiography. We have developed a completely automatic method that first restores the image with a Wiener filter, then finds the region wher...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/38/12/012

    authors: Pladellorens J,Serrat J,Castell A,Yzuel MJ

    更新日期:1993-12-01 00:00:00

  • A proposal concerning the absorbed dose conversion factor.

    abstract::New definitions of the absorbed dose conversion factors Clambda and CE are proposed. The absorbed dose in water is given by the product of absorbed dose conversion factor, exposure calibration factor, ionisation chamber reading, cap displacement correction factor and perturbation correction factor. At exposure calibra...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/23/2/003

    authors: Shiragai A

    更新日期:1978-03-01 00:00:00

  • Exact analytic reconstruction in x-ray fluorescence CT and approximated versions.

    abstract::X-ray fluorescence computed tomography (XFCT) is a relatively new synchrotron-based imaging modality aiming at reconstructing the distribution of nonradiative elements within a sample irradiated with high-intensity monochromatic x-rays. In a recent paper La Rivière (2004 Phys. Med. Biol. 49 2391-405) presented an appr...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/55/4/007

    authors: Miqueles EX,De Pierro AR

    更新日期:2010-02-21 00:00:00

  • Uncertainties in Monte Carlo-based absorbed dose calculations for an experimental benchmark.

    abstract::There is a need to verify the accuracy of general purpose Monte Carlo codes like EGSnrc, which are commonly employed for investigations of dosimetric problems in radiation therapy. A number of experimental benchmarks have been published to compare calculated values of absorbed dose to experimentally determined values....

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/19/7637

    authors: Renner F,Wulff J,Kapsch RP,Zink K

    更新日期:2015-10-07 00:00:00

  • Segmentation and classification of thyroid follicular neoplasm using cascaded convolutional neural network.

    abstract::In this paper, we present a segmentation and classification method for thyroid follicular neoplasms based on a combination of the prior-based level set method and deep convolutional neural network. The proposed method aims to discriminate thyroid follicular adenoma (TFA) and follicular thyroid carcinoma (FTC) in ultra...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abc6f2

    authors: Yang B,Yan M,Yan Z,Zhu C,Xu D,Dong F

    更新日期:2020-11-02 00:00:00

  • Evaluation of inverse methods and head models for EEG source localization using a human skull phantom.

    abstract::We used a real-skull phantom head to investigate the performances of representative methods for EEG source localization when considering various head models. We describe several experiments using a montage with current sources located at multiple positions and orientations inside a human skull filled with a conductive...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/46/1/306

    authors: Baillet S,Riera JJ,Marin G,Mangin JF,Aubert J,Garnero L

    更新日期:2001-01-01 00:00:00

  • Numerical calculation of energy deposition by broad high-energy electron beams.

    abstract::The feasibility is demonstrated of a numerical method to calculate dose deposition by broad high-energy electron beams in homogeneous matter or in heterogeneous matter in which the heterogeneities are arranged in slabs perpendicular to the beam axis. The method is based only on the basic physical interaction processes...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/34/10/003

    authors: Huizenga H,Storchi PR

    更新日期:1989-10-01 00:00:00

  • Modeling silicon diode energy response factors for use in therapeutic photon beams.

    abstract::Silicon diodes have good spatial resolution, which makes them advantageous over ionization chambers for dosimetry in fields with high dose gradients. However, silicon diodes overrespond to low-energy photons, that are more abundant in scatter which increase with large fields and larger depths. We present a cavity-theo...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/20/007

    authors: Eklund K,Ahnesjö A

    更新日期:2009-10-21 00:00:00

  • Strategies to improve 3D whole-body PET image reconstruction.

    abstract::An algorithm is described for three-dimensional whole-body (3DWB) image reconstruction in positron emission tomography. For whole-body applications, improvements to the popular fixed-axial-acceptance-angle technique are achieved by combining axially adjacent projection data available with a long-axis data set. Time-co...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/41/8/013

    authors: Cutler PD,Xu M

    更新日期:1996-08-01 00:00:00

  • Quantification of the trabecular bone volume fraction for bone marrow dosimetry in molecular radiotherapy by using a dual-energy (SPECT/)CT.

    abstract::A complete characterization of spongiosa (bone marrow plus trabecular bone) is required to calculate the absorbed dose to active bone marrow. Due to the complex microanatomy, it is necessary to apply non-conventional imaging methods in nuclear medicine. The aim of this study is validating a phantomless quantification ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/ab4476

    authors: Salas-Ramirez M,Tran-Gia J,Gbureck U,Kosmala A,Lassmann M

    更新日期:2019-10-16 00:00:00

  • Implementation of tetrahedral-mesh geometry in Monte Carlo radiation transport code PHITS.

    abstract::A new function to treat tetrahedral-mesh geometry was implemented in the particle and heavy ion transport code systems. To accelerate the computational speed in the transport process, an original algorithm was introduced to initially prepare decomposition maps for the container box of the tetrahedral-mesh geometry. Th...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aa6b45

    authors: Furuta T,Sato T,Han MC,Yeom YS,Kim CH,Brown JL,Bolch WE

    更新日期:2017-06-21 00:00:00

  • The dosimetry for a coronary artery stent coated with radioactive 188Re and 32P.

    abstract::Radiation dose distributions have been calculated for 188Re and 32P activity on a coronary artery stent. The doses have been calculated both as a function of position along the stent and of depth into the artery wall. Comparisons of the dose from identical activities of 188Re and 32P on the stent show that the major d...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/45/12/310

    authors: Fox RA,Henson PW

    更新日期:2000-12-01 00:00:00

  • Verification of the super-omni wedge concept.

    abstract::This study verifies the concept of the super-omni wedge by validating its equations for effective wedge orientation and wedge angle and by comparing the dose distributions it produces with those produced by other wedge techniques. To validate the equations, we calculated dose distributions for 20 combinations of wedge...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/46/9/313

    authors: Dai J,Zhu Y,Wu X

    更新日期:2001-09-01 00:00:00

  • Markerless positional verification using template matching and triangulation of kV images acquired during irradiation for lung tumors treated in breath-hold.

    abstract::Lung tumors treated in breath-hold are subject to inter- and intra-breath-hold variations, which makes tumor position monitoring during each breath-hold important. A markerless technique is desirable, but limited tumor visibility on kV images makes this challenging. We evaluated if template matching  +  triangulation ...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/aac1a9

    authors: Hazelaar C,Dahele M,Mostafavi H,van der Weide L,Slotman B,Verbakel W

    更新日期:2018-05-29 00:00:00

  • On the surviving fraction in irradiated multicellular tumour spheroids: calculation of overall radiosensitivity parameters, influence of hypoxia and volume effects.

    abstract::We model the heterogeneous response to radiation of multicellular tumour spheroids assuming position- and volume-dependent radiosensitivity. We propose a method to calculate the overall radiosensitivity parameters to obtain the surviving fraction of tumours. A mathematical model of a spherical tumour with a hypoxic co...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/8/005

    authors: Horas JA,Olguin OR,Rizzotto MG

    更新日期:2005-04-21 00:00:00

  • SpekCalc: a program to calculate photon spectra from tungsten anode x-ray tubes.

    abstract::A software program, SpekCalc, is presented for the calculation of x-ray spectra from tungsten anode x-ray tubes. SpekCalc was designed primarily for use in a medical physics context, for both research and education purposes, but may also be of interest to those working with x-ray tubes in industry. Noteworthy is the p...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/54/19/N01

    authors: Poludniowski G,Landry G,DeBlois F,Evans PM,Verhaegen F

    更新日期:2009-10-07 00:00:00

  • A study of the impact of x-ray tube performance on angiography system imaging efficiency.

    abstract::This work compared the impact of x-ray tube performance and automatic dose rate control (ADRC) parameter selection on system imaging efficiency of two Siemens angiography systems: a Siemens Megalix x-ray tube installed on an Artis Zee system (denoted 'MEGALIX') and a newer generation Gigalix x-ray tube installed on an...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/1361-6560/abbb7a

    authors: Dehairs M,Bosmans H,Marshall NW

    更新日期:2020-11-24 00:00:00

  • Symmetries of the 2D magnetic particle imaging system matrix.

    abstract::In magnetic particle imaging (MPI), the relation between the particle distribution and the measurement signal can be described by a linear system of equations. For 1D imaging, it can be shown that the system matrix can be expressed as a product of a convolution matrix and a Chebyshev transformation matrix. For multidi...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/60/10/4033

    authors: Weber A,Knopp T

    更新日期:2015-05-21 00:00:00

  • Comment on 'egs_brachy: a versatile and fast Monte Carlo code for brachytherapy'.

    abstract::In a recent paper (Chamberland et al 2016 Phys. Med. Biol. 61 8214) develop a new Monte Carlo code called egs_brachy for brachytherapy treatments. It is based on EGSnrc, and written in the C++ programming language. In order to benchmark the egs_brachy code, the authors use it in various test case scenarios in which co...

    journal_title:Physics in medicine and biology

    pub_type: 评论,杂志文章,信件

    doi:10.1088/1361-6560/aa9ea1

    authors: Yegin G

    更新日期:2018-02-02 00:00:00

  • An optimized workflow for the integration of biological information into radiotherapy planning: experiences with T1w DCE-MRI.

    abstract::Planning of radiotherapy is often difficult due to restrictions on morphological images. New imaging techniques enable the integration of biological information into treatment planning and help to improve the detection of vital and aggressive tumour areas. This might improve clinical outcome. However, nowadays morphol...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/50/17/020

    authors: Neff T,Kiessling F,Brix G,Baudendistel K,Zechmann C,Giesel FL,Bendl R

    更新日期:2005-09-07 00:00:00

  • Fibre-optic sensors in health care.

    abstract::Biomedical fibre-optic sensors are attractive for the measurement of physical, chemical and biochemical parameters and for spectral measurements directly performed on the patient. An overview of fibre-optic sensors for in vivo monitoring is given, with particular attention paid to the advantages that these sensors are...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章,评审

    doi:10.1088/0031-9155/42/5/015

    authors: Mignani AG,Baldini F

    更新日期:1997-05-01 00:00:00

  • Feasibility of replacing patient specific cutouts with a computer-controlled electron multileaf collimator.

    abstract::A motorized electron multileaf collimator (eMLC) was developed as an add-on device to the Varian linac for delivery of advanced electron beam therapy. It has previously been shown that electron beams collimated by an eMLC have very similar penumbra to those collimated by applicators and cutouts. Thus, manufacturing pa...

    journal_title:Physics in medicine and biology

    pub_type: 杂志文章

    doi:10.1088/0031-9155/58/16/5653

    authors: Eldib A,Jin L,Li J,Ma CM

    更新日期:2013-08-21 00:00:00