Internal dosimetry with the Monte Carlo code GATE: validation using the ICRP/ICRU female reference computational model.

abstract：:To calculate photon spectra for a 10 MV x-ray beam emitted by a medical linear accelerator, we performed numerical analysis using the aluminium transmission data obtained along the central axis of the beam under the narrow beam condition corresponding to a 3x3 cm2 field at a 100 cm distance from the source. We used th...

journal_title：Physics in medicine and biology

authors： Shimozato T,Tabushi K,Kitoh S,Shiota Y,Hirayama C,Suzuki S

更新日期：2007-01-21 00:00:00

abstract：:It has been reported that the dose effects of metallic guidewires are significant in intravascular brachytherapy (IVBT) using a beta source. The purpose of this work is to investigate the dependence of these dose effects on guidewire position. The EGS4 Monte Carlo codes were used to perform the dose calculations for t...

journal_title：Physics in medicine and biology

authors： Shih R,Hsu WL,Li XA

更新日期：2002-05-21 00:00:00

abstract：:Intensity modulated radiation therapy (IMRT) inverse planning using total-variation (TV) regularization has been proposed to reduce the complexity of fluence maps and facilitate dose delivery. Conventionally, the optimization problem with L-1 norm is solved with quadratic programming (QP), which is time consuming and ...

journal_title：Physics in medicine and biology

authors： Kim H,Suh TS,Lee R,Xing L,Li R

更新日期：2012-07-07 00:00:00

abstract：:The prompt-gamma neutron activation facility at Brookhaven National Laboratory was upgraded to improve both the precision and accuracy of its in vivo determinations of total body nitrogen. The upgrade, guided by Monte Carlo simulations, involved elongating and modifying the source collimator and its shielding, reposit...

journal_title：Physics in medicine and biology

authors： Dilmanian FA,Lidofsky LJ,Stamatelatos I,Kamen Y,Yasumura S,Vartsky D,Pierson RN Jr,Weber DA,Moore RI,Ma R

更新日期：1998-02-01 00:00:00

abstract：:This study presents the first observation of shear waves induced remotely within soft tissues. It was performed through the combination of a transcranial magnetic stimulation device and a permanent magnet. A physical model based on Maxwell and Navier equations was developed. Experiments were performed on a cryogel pha...

journal_title：Physics in medicine and biology

authors： Grasland-Mongrain P,Miller-Jolicoeur E,Tang A,Catheline S,Cloutier G

更新日期：2016-03-21 00:00:00

abstract：:The classical Sievert integral method is a valuable tool for dose rate calculations around brachytherapy sources, combining simplicity with reasonable computational times. However, its accuracy in predicting dose rate anisotropy around 192Ir brachytherapy sources has been repeatedly put into question. In this work, we...

journal_title：Physics in medicine and biology

authors： Karaiskos P,Angelopoulos A,Baras P,Rozaki-Mavrouli H,Sandilos P,Vlachos L,Sakelliou L

更新日期：2000-02-01 00:00:00

abstract：:Biomedical fibre-optic sensors are attractive for the measurement of physical, chemical and biochemical parameters and for spectral measurements directly performed on the patient. An overview of fibre-optic sensors for in vivo monitoring is given, with particular attention paid to the advantages that these sensors are...

journal_title：Physics in medicine and biology

authors： Mignani AG,Baldini F

更新日期：1997-05-01 00:00:00

abstract：:The aim of this study is the evaluation of on-the-fly volume of intersection computation for system's geometry modelling in 3D PET image reconstruction. For this purpose we propose a simple geometrical model in which the cubic image voxels on the given Cartesian grid are approximated with spheres and the rectangular t...

journal_title：Physics in medicine and biology

authors： Lougovski A,Hofheinz F,Maus J,Schramm G,Will E,van den Hoff J

更新日期：2014-02-07 00:00:00

abstract：:We explore how the radioactive background from naturally occurring 176Lu affects single photon transmission imaging for lutetium orthosilicate (LSO) scintillator-based PET cameras by estimating the transmission noise equivalent count rate (NECR) including this background. Assuming a typical PET camera geometry (80 cm ...

journal_title：Physics in medicine and biology

authors： Huber JS,Moses WW,Jones WF,Watson CC

更新日期：2002-10-07 00:00:00

abstract：:A method has been developed which, by using the geometric information from treatment sample cases, selects from a given data set an initial treatment plan as a step for treatment plan optimization. The method uses an artificial neural network (ANN) classification technique to select a best matching plan from the 'opti...

journal_title：Physics in medicine and biology

authors： Hosseini-Ashrafi ME,Bagherebadian H,Yahaqi E

更新日期：1999-06-01 00:00:00

abstract：:Quantitative assessment of mammographic asymmetry has been investigated for breast cancer risk prediction. A new asymmetry feature extraction method was proposed in this study to enhance the risk prediction accuracy of near-term breast cancer. Breast areas in each pair of bilateral mammographic images were divided int...

journal_title：Physics in medicine and biology

authors： Yan S,Zhang L,Song C

更新日期：2018-10-17 00:00:00

abstract：:Using MRI for radiotherapy treatment planning and image guidance is appealing as it provides superior soft tissue information over CT scans and avoids possible systematic errors introduced by aligning MR to CT images. This study presents a method that generates Synthetic CT (MRCT) volumes by performing probabilistic t...

journal_title：Physics in medicine and biology

authors： Liu L,Jolly S,Cao Y,Vineberg K,Fessler JA,Balter JM

更新日期：2017-04-21 00:00:00

abstract：:The design and performance of a dosimetric system for the irradiation of thin biological samples with therapeutic proton beams is reported. Protons with initial energies between 40 MeV and 250 MeV are degraded with polystyrene blocks of variable thickness in order to place the sample, an aqueous layer of 10 microm thi...

journal_title：Physics in medicine and biology

authors： Bashkirov V,Schulte RW

更新日期：2002-02-07 00:00:00

abstract：:Grating-based x-ray phase-contrast imaging provides three simultaneous image channels originating from a single image acquisition. While the phase signal provides direct access to the electron density in tomography, there is additional information on sub-resolutional structural information which is called dark-field s...

journal_title：Physics in medicine and biology

authors： Braig EM,Pfeiffer D,Willner M,Sellerer T,Taphorn K,Petrich C,Scholz J,Petzold L,Birnbacher L,Dierolf M,Pfeiffer F,Herzen J

更新日期：2020-09-18 00:00:00

abstract：:Large blood vessels can produce steep temperature gradients in heated tissues leading to inadequate tissue temperatures during hyperthermia. This paper utilizes a finite difference scheme to solve the basic equations of heat transfer and fluid flow to model blood vessel cooling. Unlike previous formulations, heat tran...

journal_title：Physics in medicine and biology

authors： Kolios MC,Sherar MD,Hunt JW

更新日期：1995-04-01 00:00:00

abstract：:We study the spatial distributions of beta(+)-activity produced by therapeutic beams of (3)He and (12)C ions in various tissue-like materials. The calculations were performed within a Monte Carlo model for heavy-ion therapy (MCHIT) based on the GEANT4 toolkit. The contributions from positron-emitting nuclei with T(1/2...

journal_title：Physics in medicine and biology

authors： Pshenichnov I,Larionov A,Mishustin I,Greiner W

更新日期：2007-12-21 00:00:00

abstract：:In positron emission tomography (PET), there is an increasing interest in studying not only the regional mean tracer concentration, but its variation arising from local differences in physiology, the tissue heterogeneity. However, in reconstructed images this physiological variation is shadowed by a large reconstructi...

journal_title：Physics in medicine and biology

authors： Forma J,Niemi JA,Ruotsalainen U

更新日期：2013-07-21 00:00:00

abstract：:Experimental radiobiological investigations of fast neutron beams involve irradiation of thin cell layers. The irradiation of cells is done either in free air or with a material such as graphite, TE plastic or bone-equivalent plastic covering the cells. This paper discusses the computed dose distributions in LET at sh...

journal_title：Physics in medicine and biology

authors： Bhatia DP,Nagarajan PS

更新日期：1979-09-01 00:00:00

abstract：:The widely applied single-interaction analytic expression characterizing the energy resolution component of the angular resolution precision for an electronically collimated point source is extended to include multiple-interaction Compton scatter sequences as well as sequences terminated by photoelectric absorption. T...

journal_title：Physics in medicine and biology

authors： Durkee JW Jr,Antich PP,Tsyganov EN,Constantinescu A,Kulkarni PV,Smith BJ,Arbique GM,Lewis MA,Nguyen T,Raheja A,Thambi G,Parkey RW

更新日期：1998-10-01 00:00:00

abstract：:The University of Washington (UW) Clinical Neutron Therapy System (CNTS) has been used to treat over 3300 patients. Treatment planning for these patients is currently performed using an MV x-ray model in Pinnacle® adapted to fit measurements of fast neutron output factors, wedge factors, depth-dose and lateral profile...

journal_title：Physics in medicine and biology

authors： Moffitt GB,Wootton LS,Hårdemark B,Sandison GA,Laramore GE,Parvathaneni U,Stewart RD

更新日期：2020-08-31 00:00:00

abstract：:We have developed and tested a GSO (gadolinium oxyorthosilicate) position-sensitive gamma detector which can be used with positron and single-photon radionuclides for imaging breast cancer or sentinel lymph node detection. Because GSO has a relatively good energy resolution for annihilation gammas as well as low energ...

journal_title：Physics in medicine and biology

authors： Yamamoto S,Matsumoto K,Senda M

更新日期：2006-01-21 00:00:00

abstract：:EEG recordings made in combined EEG-fMRI studies are corrupted by gradient artefacts (GAs) resulting from the interaction of the EEG system with the time-varying magnetic field gradients used in MRI. The dominant contribution to the GA arises from interaction with the leads of the EEG cap and the human head, but artef...

journal_title：Physics in medicine and biology

authors： Chowdhury ME,Mullinger KJ,Bowtell R

更新日期：2015-06-21 00:00:00

abstract：:Speed of sound (SOS) measurements, typically made using 1 MHz broadband pulses, are increasingly used in the clinical diagnosis of bone disorders. Previous in vitro studies indicate that broadband ultrasound pulses are susceptible to distortion in cancellous bone, leading to imprecise arrival time and SOS measurements...

journal_title：Physics in medicine and biology

authors： Pollintine P,Haddaway MJ,Davie MW

更新日期：2000-07-01 00:00:00

abstract：:Gold nanoparticles (GNPs) have shown potential in recent years as a means of therapeutic dose enhancement in radiation therapy. However, a major challenge in moving towards clinical implementation is the exact characterisation of the dose enhancement they provide. Monte Carlo studies attempt to explore this property, ...

journal_title：Physics in medicine and biology

authors： Koger B,Kirkby C

更新日期：2016-03-07 00:00:00

abstract：:The objective of this paper is to evaluate an iterative maximum likelihood (ML) cone-beam computed tomography (CBCT) reconstruction with total variation (TV) regularization with respect to the robustness of the algorithm due to data inconsistencies. Three different and (for clinical application) typical classes of err...

journal_title：Physics in medicine and biology

authors： Stsepankou D,Arns A,Ng SK,Zygmanski P,Hesser J

更新日期：2012-10-07 00:00:00

abstract：:Simulation of small-angle x-ray scattering from collagen in healthy and cancerous breast tissue may reveal detailed information on the structural changes in collagen. Collagen fibril is modelled as a cylinder with axially periodic step-function electron density, and packing is approximated by placing the cylinders in ...

journal_title：Physics in medicine and biology

authors： Suhonen H,Fernández M,Serimaa R,Suortti P

更新日期：2005-11-21 00:00:00

abstract：:Elasticity imaging (EI) is being developed to allow the evaluation of the mechanical properties of soft tissue, but these properties are already assessed in routine ultrasound breast examination using a method that involves the subjective interpretation of tissue motion seen in real-time B-mode image movies during pal...

journal_title：Physics in medicine and biology

authors： Miller NR,Bamber JC

更新日期：2000-08-01 00:00:00

abstract：:A mathematical transcription of the intrinsic circuit of the CA1 region of the rat dorsal hippocampus was made and the model parameters adjusted according to experimental data from intracellular recordings and single channel kinetics. This model was able to simulate well the profile of the field potentials recorded ex...

journal_title：Physics in medicine and biology

authors： Almeida AC,Fernandes de Lima VM,Infantosi AF

更新日期：1998-09-01 00:00:00

abstract：:In this paper, we present a segmentation and classification method for thyroid follicular neoplasms based on a combination of the prior-based level set method and deep convolutional neural network. The proposed method aims to discriminate thyroid follicular adenoma (TFA) and follicular thyroid carcinoma (FTC) in ultra...

journal_title：Physics in medicine and biology

authors： Yang B,Yan M,Yan Z,Zhu C,Xu D,Dong F

更新日期：2020-11-02 00:00:00

abstract：:The spatial resolution of 2D detector arrays equipped with ionization chambers or diodes, used for the dose verification of IMRT treatment plans, is limited by the size of the single detector and the centre-to-centre distance between the detectors. Optimization criteria with regard to these parameters have been develo...

journal_title：Physics in medicine and biology

authors： Poppe B,Djouguela A,Blechschmidt A,Willborn K,Rühmann A,Harder D

更新日期：2007-05-21 00:00:00