Intravoxel Incoherent Motion Imaging in Small Vessel Disease: Microstructural Integrity and Microvascular Perfusion Related to Cognition.

abstract：:The gerbil model was used to assess the therapeutic effects of the calcium antagonist nimodipine on cerebral ischemia. Transient cerebral ischemia was produced in each gerbil by bilateral common carotid occlusion of 10-, 15- or 20-min duration. Nimodipine (0.01 or 0.1 mg/kg) was administered intraperitoneally just bef...

journal_title：Stroke

authors： Fujisawa A,Matsumoto M,Matsuyama T,Ueda H,Wanaka A,Yoneda S,Kimura K,Kamada T

更新日期：1986-07-01 00:00:00

abstract：:MRI is becoming the imaging modality of choice in patients with ischemic cerebrovascular disease although CT is still the test of choice to exclude acute hemorrhagic stroke. We have briefly reviewed characteristic features of ischemic and hemorrhagic cerebrovascular disease as well as vascular anomalies as seen on MRI...

journal_title：Stroke

authors： Ramadan NM,Deveshwar R,Levine SR

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:While brain tissue lactate increases during cerebral ischemia and is known to be important in the pathogenesis of ischemic brain injury, patterns of extracellular lactate accumulation have been less well characterized, and the influence of brain temperature has not been previously investigated. M...

journal_title：Stroke

authors： Lin B,Busto R,Globus MY,Martinez E,Ginsberg MD

更新日期：1995-09-01 00:00:00

abstract：:During the 5-year period from 1980 to 1984, the incidence of subarachnoid hemorrhage due only to rupture of aneurysms was investigated in Izumo City, a small city with a population of 79,026. Additionally, to ascertain the relation of incidence to the size of the geographic area and/or population, a similar analysis w...

journal_title：Stroke

authors： Inagawa T,Ishikawa S,Aoki H,Takahashi M,Yoshimoto H

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Carotid endarterectomy reduces the risk of carotid territory ischemic stroke ipsilateral to a recently symptomatic severe carotid stenosis. However, the benefit is limited by the risks of stroke and death associated with the operation. Although reported surgical risks vary enormously, there has b...

journal_title：Stroke

authors： Rothwell PM,Slattery J,Warlow CP

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Few studies are available that have addressed the prevalence of early-onset dementia (EOD), including early-onset Alzheimer disease and other forms of dementia in Japan. METHODS:A 2-step postal survey was sent to all of the 2475 institutions providing medical or care services for individuals wit...

journal_title：Stroke

authors： Ikejima C,Yasuno F,Mizukami K,Sasaki M,Tanimukai S,Asada T

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Patients with atrial fibrillation have a high risk of stroke and other vascular events even if anticoagulated. The primary objective here is to determine whether routine blood pressure-lowering provides additional protection for this high-risk patient group. METHODS:This study was a subsidiary a...

journal_title：Stroke

authors： Arima H,Hart RG,Colman S,Chalmers J,Anderson C,Rodgers A,Woodward M,MacMahon S,Neal B,PROGRESS Collaborative Group.

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Despite its high prevalence in stroke survivors, there is little clinical research on bowel dysfunction in this population. This is the first randomized controlled trial to evaluate treatment of constipation and fecal incontinence in stroke survivors. METHODS:Stroke patients with constipation or...

journal_title：Stroke

authors： Harari D,Norton C,Lockwood L,Swift C

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Prophylactic administration of simvastatin has been shown to protect against brain damage and its long-lasting behavioral consequences in neonatal rats. To establish the drug treatment window, we evaluated the effectiveness of simvastatin administered at different intervals before and after strok...

journal_title：Stroke

authors： Balduini W,Mazzoni E,Carloni S,De Simoni MG,Perego C,Sironi L,Cimino M

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Hetereothermic mammals tolerate hypoxia during euthermy and torpor, and evidence suggests this tolerance may extend beyond hypoxia to cerebral ischemia. During hibernation, CA1 hippocampal neurons endure extreme fluctuations in cerebral blood flow during transitions into and out of torpor as well...

journal_title：Stroke

authors： Dave KR,Prado R,Raval AP,Drew KL,Perez-Pinzon MA

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The first goal of this study was to determine the effect of glutamate on permeability and reactivity of the cerebral microcirculation. The second goal of this study was to determine a possible role for nitric oxide in the effects of glutamate on the cerebral microcirculation. METHODS:We examined...

journal_title：Stroke

authors： Mayhan WG,Didion SP

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND AND PURPOSE:In a previous study from our laboratory, ritanserin, a specific 5-HT2 serotonin receptor antagonist, reduced ischemic damage in the setting of transient global ischemia. In this study, we examined the effect of ritanserin on ischemic cerebral blood flow, systemic blood pressure, and infarct volum...

journal_title：Stroke

authors： Takagi K,Ginsberg MD,Globus MY,Busto R,Dietrich WD

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Data from recent multicenter carotid endarterectomy trials have questioned the validity and reliability of Doppler ultrasound in the assessment of carotid stenosis. METHODS:We prospectively analyzed 45 patients undergoing carotid angiography to compare the North American Symptomatic Carotid Enda...

journal_title：Stroke

authors： Alexandrov AV,Bladin CF,Maggisano R,Norris JW

更新日期：1993-09-01 00:00:00

abstract：:Background and Purpose- Timely access to endovascular thrombectomy (EVT) centers is vital for best acute ischemic stroke outcomes. Methods- US stroke-treating centers were mapped utilizing geo-mapping and stratified into non-EVT or EVT if they reported ≥1 acute ischemic stroke thrombectomy code in 2017 to Center for M...

journal_title：Stroke

authors： Sarraj A,Savitz S,Pujara D,Kamal H,Carroll K,Shaker F,Reddy S,Parsha K,Fournier LE,Jones EM,Sharrief A,Martin-Schild S,Grotta J

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Most patients have elevated blood pressure (BP) in the early phase after an acute ischemic stroke. Mechanism and effects of this BP elevation are not well understood. The benefits of intervention by lowering the initial BP or waiting for spontaneous return to normal values remain debated. We stud...

journal_title：Stroke

authors： Yong M,Diener HC,Kaste M,Mau J

更新日期：2005-12-01 00:00:00

abstract：:Using in vivo brain microdialysis, we studied amino acid release in the striatum and cortex of eight rats following permanent middle cerebral artery occlusion. We then processed all brains for histopathologic assessment of the volume of ischemic damage 4 hours after occlusion. Ischemic damage was varied by occlusion o...

journal_title：Stroke

authors： Butcher SP,Bullock R,Graham DI,McCulloch J

更新日期：1990-12-01 00:00:00

abstract：:Background and Purpose- We aimed to compare outcomes of ischemic stroke patients with nonvalvular atrial fibrillation between earlier and later initiation of direct oral anticoagulants (DOACs) after stroke onset. Methods- From data for 1192 nonvalvular atrial fibrillation patients with acute ischemic stroke or transie...

journal_title：Stroke

authors： Mizoguchi T,Tanaka K,Toyoda K,Yoshimura S,Itabashi R,Takagi M,Todo K,Shiozawa M,Yagita Y,Yoshimoto T,Terasaki T,Yamagami H,Takizawa S,Inoue M,Kamiyama K,Ihara M,Okada Y,Kitazono T,Koga M,SAMURAI Study Investigators.

更新日期：2020-03-01 00:00:00

abstract：:The effect of prostaglandin E1 on regional cerebral blood flow (rCBF) was studied with the intra-arterial 133Xe method in ten awake patients under local anesthesia. Measurements were taken from 16 areas of a hemisphere in seven patients, from 35 areas of a hemisphere in two patients and from 256 areas of a hemisphere ...

journal_title：Stroke

authors： Olesen J

更新日期：1976-11-01 00:00:00

abstract：:Cerebral blood flow was studied in rabbits immediately following complete circulatory stasis of varying duration. Systemic arterial pressure was measured continuously. The postischemic circulation was examined both by an infusion of carbon black and, in separate experiments, by injection of 14C-antipyrine into the blo...

journal_title：Stroke

authors： Fischer EG,Ames A 3rd,Lorenzo AV

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Autopsy series of patients with AIDS have found a 4% to 29% prevalence of cerebral infarction. Little is known of the prevalence of cerebral infarction when not associated with non-HIV central nervous system (CNS) infection, lymphoma, or cardioembolic sources. Clinical correlation has seldom been...

journal_title：Stroke

authors： Connor MD,Lammie GA,Bell JE,Warlow CP,Simmonds P,Brettle RD

更新日期：2000-09-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There have not been any new epidemiological studies related to stroke in Tibet for 20 years. This study aimed to collect stroke data from The City Staff Medical Insurance Registry in Lhasa, Tibet, to describe the incidence, clinical subtypes, and associated risk factors of stroke. METHODS:We use...

journal_title：Stroke

authors： Zhao Y,Yao Z,D'Souza W,Zhu C,Chun H,Zhuoga C,Zhang Q,Hu X,Zhou D

更新日期：2010-12-01 00:00:00

abstract：BACKGROUND AND PURPOSE:The American Heart Association/American Stroke Association and Department of Health Stroke Coverdell Program convened a stakeholder meeting in upstate NY to develop recommendations to enhance stroke systems for acute large vessel occlusion. METHODS:Prehospital, hospital, and Department of Health...

journal_title：Stroke

authors： Magdon-Ismail Z,Benesch C,Cushman JT,Brissette I,Southerland AM,Brandler ES,Sozener CB,Flor S,Hemmitt R,Wales K,Parrigan K,Levine SR,Upstate New York Stroke Work Groups.

更新日期：2017-07-01 00:00:00

abstract：:Previous studies suggest that rheological changes associated with ischemia may produce postischemic hypoperfusion. We tested whether intracarotid or intravenous infusions of saline improve neurological outcome from incomplete cerebral ischemia in rats. Rats were anesthetized with 1.4% isoflurane in air, and ischemia w...

journal_title：Stroke

authors： Hoffman WE,Ferguson L,Thomas C,Albrecht RF

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Dichloroacetate facilitates a decrease in brain lactate during reperfusion after incomplete ischemia. This study examined the possible activation of pyruvate dehydrogenase enzyme by dichloroacetate to explain this effect. Because the duration of ischemia and hyperglycemia exacerbate ischemic brai...

journal_title：Stroke

authors： Dimlich RV,Nielsen MM

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Quantitative data on sensory impairment in stroke patients are limited. We measured the perception thresholds for temperature and thermal pain in patients with different lacunar syndromes, correlated the results with clinical and magnetic resonance imaging (MRI) findings, and studied the long-ter...

journal_title：Stroke

authors： Samuelsson M,Samuelsson L,Lindell D

更新日期：1994-11-01 00:00:00

abstract：:In patients with subarachnoid hemorrhage, particularly hemorrhage due to aneurysmal rupture, there was a positive significant relation between angiographic vessel constriction and vessel pathology (angiopathy). Furthermore, there was a positive relationship between post-hemorrhage survival time and the severity of ang...

journal_title：Stroke

authors： Smith RR,Clower BR,Peeler DF Jr,Yoshioka J

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Single and multiple lacunar infarctions may have some difference in underlying diseases and cerebral blood flows. To determine the difference, we investigated underlying diseases and cerebral blood flows in single and multiple lacunar infarctions. METHODS:Fifteen cases of lacunar infarction, 10 ...

journal_title：Stroke

authors： Mochizuki Y,Oishi M,Takasu T

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND AND PURPOSE:There have been very few population-based cohort studies of long-term prognosis and risk factors for death after stroke. We examined the 10-year prognosis, causes, and risk factors of death after stroke in a Japanese cohort. METHODS:During a 26-year follow-up of a cohort of 1621 subjects > or =4...

journal_title：Stroke

authors： Kiyohara Y,Kubo M,Kato I,Tanizaki Y,Tanaka K,Okubo K,Nakamura H,Iida M

更新日期：2003-10-01 00:00:00

abstract：:Background and Purpose- Persistent depression after ischemic stroke is common in stroke survivors and may be even higher in family caregivers, but few studies have examined depressive symptom levels and their predictors in patient and caregiver groups simultaneously. Methods- Stroke survivors and their family caregive...

journal_title：Stroke

authors： Roth DL,Haley WE,Sheehan OC,Liu C,Clay OJ,Rhodes JD,Judd SE,Dhamoon M

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND AND PURPOSE:Because thromboembolic events are frequently observed in primary antiphospholipid syndrome (PAPS), we assessed the risk factors for new thrombotic episodes. METHODS:Fifty-six PAPS patients (mean age, 37+/-10 years) were prospectively studied for 5 years. The preliminary Sapporo classification cr...

journal_title：Stroke

authors： Turiel M,Sarzi-Puttini P,Peretti R,Rossi E,Atzeni F,Parsons W,Doria A

更新日期：2005-07-01 00:00:00