Can we use plasma hyperosmolality as a predictor of mortality for ST-segment elevation myocardial infarction?

Abstract:

BACKGROUND:The aim of this study was to investigate the association of plasma osmolality with all-cause mortality in ST-segment elevation myocardial infarction (STEMI) patients treated with a primary percutaneous coronary intervention. METHODS:This study included 3748 patients (mean age 58.3±11.8 years, men 81%) with STEMI treated with primary percutaneous coronary intervention. The following formula was used to measure the plasma osmolality at admission: osmolality=1.86×sodium (mmol/l)+glucose (mg/dl)/18+BUN (mg/dl)/2.8+9. RESULTS:The patients were followed up for a mean period of 22±10 months. Patients with higher plasma osmolality had 3.7 times higher in-hospital (95% confidence interval: 2.7-5.1) and 3.2 times higher long-term (95% confidence interval: 2.5-4.1) all-cause mortality rates than patients with lower plasma osmolality. CONCLUSION:Plasma osmolality was found to be a predictor of both in-hospital and long-term all-cause mortality. Hence, plasma osmolality can be used to detect high-risk patients in STEMI.

journal_name

Coron Artery Dis

journal_title

Coronary artery disease

authors

Tatlisu MA,Kaya A,Keskin M,Uzman O,Borklu EB,Cinier G,Hayiroglu MI,Tatlisu K,Eren M

doi

10.1097/MCA.0000000000000426

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

70-76

issue

1

eissn

0954-6928

issn

1473-5830

journal_volume

28

pub_type

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