Three-dimensional auditory localization in the echolocating bat.

abstract：:In vivo tau imaging allows a deeper understanding of tau deposition in the brain, providing insights into the causes, diagnosis and treatment of primary and secondary tauopathies such as Alzheimer's disease, progressive supranuclear palsy, corticobasal syndrome, chronic traumatic encephalopathy, and some variants of f...

journal_title：Current opinion in neurobiology

authors： Villemagne VL,Okamura N

更新日期：2016-02-01 00:00:00

abstract：:Upon receiving injury signals, neurons can activate various pathways to reduce harm, initiate neuroprotection, and repair damaged neurite without cell death. Here, we review recent progresses in the study of neurite repair focusing on neuronal cell-autonomous mechanisms, including new findings on ion channels that ser...

journal_title：Current opinion in neurobiology

authors： Liu HH,Jan YN

更新日期：2020-08-01 00:00:00

abstract：:Recent results have shown the possibility of both reconstructing connectomes of small but biologically interesting circuits and extracting from these connectomes insights into their function. However, these reconstructions were heroic proof-of-concept experiments, requiring person-months of effort per neuron reconstru...

journal_title：Current opinion in neurobiology

authors： Plaza SM,Scheffer LK,Chklovskii DB

更新日期：2014-04-01 00:00:00

abstract：:Functional magnetic resonance imaging (fMRI) is used widely to determine the spatial layout of brain activation associated with specific cognitive tasks at a spatial scale of millimeters. Recent methodological improvements have made it possible to determine the latency and temporal structure of the activation at a tem...

journal_title：Current opinion in neurobiology

authors： Formisano E,Goebel R

更新日期：2003-04-01 00:00:00

abstract：:Vision research has traditionally been studied in stationary subjects observing stimuli, and rarely during navigation. Recent research using virtual reality environments for mice has revealed that responses even in the primary visual cortex are modulated by spatial context - identical scenes presented in different pos...

journal_title：Current opinion in neurobiology

authors： Saleem AB

更新日期：2020-10-01 00:00:00

abstract：:This past year has seen significant advances in our understanding of the physiology of emotion. Attention continues to focus on the amygdala and its interconnections with prefrontal cortical regions. New evidence underscores the importance of lateralization for emotion. There are also new findings on the physiological...

journal_title：Current opinion in neurobiology

authors： Davidson RJ,Sutton SK

更新日期：1995-04-01 00:00:00

abstract：:Expression of vnd in ventral, ind in intermediate, and msh in dorsal columns of fly neurectoderm, and of homologous gene families in corresponding domains of vertebrate neurectoderm, suggests that elements of dorsoventral neural patterning have been evolutionarily conserved. However, upstream signaling pathways regula...

journal_title：Current opinion in neurobiology

authors： Cornell RA,Ohlen TV

更新日期：2000-02-01 00:00:00

abstract：:Slow axonal transport conveys cytosolic and cytoskeletal proteins into axons and synapses at overall velocities that are several orders of magnitude slower than the fast transport of membranous organelles such as vesicles and mitochondria. The phenomenon of slow transport was characterized by in vivo pulse-chase radio...

journal_title：Current opinion in neurobiology

authors： Roy S

更新日期：2020-08-01 00:00:00

abstract：:A fundamental but unsolved problem in neuroscience is how connections between neurons might underlie information processing in central circuits. Building wiring diagrams of neural networks may accelerate our understanding of how they compute. But even if we had wiring diagrams, it is critical to know what neurons in a...

journal_title：Current opinion in neurobiology

authors： Lee WC,Reid RC

更新日期：2011-10-01 00:00:00

abstract：:Cortical networks receive a highly variable stream of inputs from internal and external influences, and must flexibly adapt their operations on a short timescale. Recent work has highlighted this state-dependent functional flexibility of cortical circuits and provided initial insights into underlying circuit-level mec...

journal_title：Current opinion in neurobiology

authors： Cardin JA

更新日期：2019-10-01 00:00:00

abstract：:Reverse genetic techniques, including gene 'knockouts' and transgenesis, allow defined mutations to be introduced into the mouse genome. The application of these techniques to neurobiology is beginning to provide a bridge between genes and cognition. Specifically, genetically altered mice make it possible to explore m...

journal_title：Current opinion in neurobiology

authors： Mayford M,Abel T,Kandel ER

更新日期：1995-04-01 00:00:00

abstract：:Mosquitoes use their sense of smell to find hosts, nectar, and oviposition sites, and to avoid repellents. A small number of mosquito species are adapted to feed on humans and have a major impact on public health by transmitting diseases such as malaria, dengue and filariasis. The application of odorants for behaviora...

journal_title：Current opinion in neurobiology

authors： Ray A

更新日期：2015-10-01 00:00:00

abstract：:Central core (brainstem, diencephalic and basal forebrain) systems influence the functional modes of thalamic and cortical neurons during behavioral states of vigilance. Recent studies in vivo and in vitro have focused on the cellular properties of central core systems and their modulation of slow sleep oscillations, ...

journal_title：Current opinion in neurobiology

authors： Steriade M

更新日期：1993-08-01 00:00:00

abstract：:For many years, it has been postulated that interactions between motor commands and somatic perception in the sensorimotor cortices exist, but they have been difficult to demonstrate. Recent studies have made demonstration of this interaction easier and suggest that cortical activity related to somatic sensation and p...

journal_title：Current opinion in neurobiology

authors： Nelson RJ

更新日期：1996-12-01 00:00:00

abstract：:Recent psychophysical studies on normal subjects, as well as brain imaging studies, have revised the concepts concerning the mechanisms underlying spatial orientation during navigation tasks. The emphasis has been put on internal models that allow the prediction of a planned trajectory and are essential in the steerin...

journal_title：Current opinion in neurobiology

authors： Berthoz A,Viaud-Delmon I

更新日期：1999-12-01 00:00:00

abstract：:Iterated learning describes the process whereby an individual learns their behaviour by exposure to another individual's behaviour, who themselves learnt it in the same way. It can be seen as a key mechanism of cultural evolution. We review various methods for understanding how behaviour is shaped by the iterated lear...

journal_title：Current opinion in neurobiology

authors： Kirby S,Griffiths T,Smith K

更新日期：2014-10-01 00:00:00

abstract：:High densities of acetylcholine receptors and sodium channels in the crests and troughs of the postsynaptic folds, respectively, ensure reliable neuromuscular signalling. Clustering of both ion channels is mediated by agrin. In the case of acetylcholine receptors, agrin activates the tyrosine kinase receptor muscle-sp...

journal_title：Current opinion in neurobiology

authors： Colledge M,Froehner SC

更新日期：1998-06-01 00:00:00

abstract：:Selective transport of transmembrane proteins to different intracellular compartments often involves the recognition of sorting signals in the cytosolic domains of the proteins by components of membrane coats. Some of these coats have as their key components a family of heterotetrameric adaptor protein (AP) complexes ...

journal_title：Current opinion in neurobiology

authors： Guardia CM,De Pace R,Mattera R,Bonifacino JS

更新日期：2018-08-01 00:00:00

abstract：:Molecular mechanisms involved in the various stages of transmitter secretion have been studied by perturbing the composition of secretory cells using pharmacological and biochemical agents. An emerging approach is to reconstitute individual steps or the entire sequence of secretion mechanisms in non-secretory cells by...

journal_title：Current opinion in neurobiology

authors： Alder J,Poo MM

更新日期：1993-06-01 00:00:00

abstract：:Most high-level sensory neurons have complex, nonlinear response properties; a comprehensive characterization of these properties remains a formidable challenge. Recent studies using complex sensory stimuli combined with linear and nonlinear analyses have provided new insights into the neuronal response properties in ...

journal_title：Current opinion in neurobiology

authors： Touryan J,Dan Y

更新日期：2001-08-01 00:00:00

abstract：:PTEN germline mutations are found in a small subset of children diagnosed with autism spectrum disorder (ASD) and accompanying macrocephaly. In this review, we discuss recent advances that offer insight into the pathogenesis of this subgroup of autism patients. We provide an overview of how disrupting PTEN function in...

journal_title：Current opinion in neurobiology

authors： Zhou J,Parada LF

更新日期：2012-10-01 00:00:00

abstract：:Enduring social bonds play an essential role in human society. These bonds positively affect psychological, physiological, and behavioral functions. Here, we review the recent literature on the neurobiology, particularly the role of oxytocin and dopamine, of pair bond formation, bond disruption, and social buffering e...

journal_title：Current opinion in neurobiology

authors： Lieberwirth C,Wang Z

更新日期：2016-10-01 00:00:00

abstract：:The study of spatial maps of the ventral sensory-motor cortex (vSMC) dates back to the earliest cortical stimulation studies. This review surveys a number of recent and historical reports of the features and function of spatial maps within vSMC towards the human behavior of speaking. Representations of the vocal tract...

journal_title：Current opinion in neurobiology

authors： Conant D,Bouchard KE,Chang EF

更新日期：2014-02-01 00:00:00

abstract：:The development of motor behaviour depends on the differentiation of underlying circuitry. Recent work with the zebrafish brings the simple swimming behaviour of lower vertebrates and their embryos into focus as a suitable model to study the development of motor circuitry and its genetic control. Changes in connectivi...

journal_title：Current opinion in neurobiology

authors： Bate M

更新日期：1999-12-01 00:00:00

abstract：:Rhythms are a prominent signature of brain activity. Their expression is correlated with numerous examples of healthy information processing and their fluctuations are a marker of disease states. Yet, their causal or epiphenomenal role in brain function is still highly debated. We review recent studies showing brain r...

journal_title：Current opinion in neurobiology

authors： Jones SR

更新日期：2016-10-01 00:00:00

abstract：:Recent advances in the identification of factors that inhibit axon extension lead us to suggest that there exist at least two functionally distinct categories of inhibitory factors: those that inhibit the motile apparatus of the growth cone, and those that destabilize interactions of the growth cone with the substratu...

journal_title：Current opinion in neurobiology

authors： Luo Y,Raper JA

更新日期：1994-10-01 00:00:00

abstract：:Neural oscillations are ubiquitous in olfactory systems of mammals, insects and molluscs. Neurophysiological and computational investigations point to common mechanisms for gamma or odor associated oscillations across phyla (40-100Hz in mammals, 20-30Hz in insects, 0.5-1.5Hz in molluscs), engaging the reciprocal dendr...

journal_title：Current opinion in neurobiology

authors： Kay LM

更新日期：2015-04-01 00:00:00

abstract：:Inhibitory molecules in CNS myelin affect axonal regeneration after injury. In the past year, myelin-associated glycoprotein (MAG), a well-characterized myelin protein, has been identified as an inhibitor of axonal regeneration. This finding, together with its established ability to promote outgrowth, defines MAG as a...

journal_title：Current opinion in neurobiology

authors： Filbin MT

更新日期：1995-10-01 00:00:00

abstract：:Our understanding of the gut system has been revolutionized over the past decade, in particular regarding its role in immune control and psychological regulation. The vagus nerve is a crucial link between gut and brain, transmitting diverse gut-derived signals, and has been implicated in many gastrointestinal, neurolo...

journal_title：Current opinion in neurobiology

authors： Yu CD,Xu QJ,Chang RB

更新日期：2020-06-01 00:00:00

abstract：:In order to understand how brain activity produces adaptive behavior we need large-scale, high-resolution recordings of neuronal activity. Fluorescent genetically encoded voltage indicators (GEVIs) offer the potential for these recordings to be performed chronically from targeted cells in a minimally invasive manner. ...

journal_title：Current opinion in neurobiology

authors： Platisa J,Pieribone VA

更新日期：2018-06-01 00:00:00