Abstract:
:The vaginal microbiota has great significance in maintaining vaginal health and protecting the host from disease. Recent advances in molecular techniques and informatics allow researchers to explore microbial composition in detail and to compare the structure of vaginal microbial communities with behavior and health outcomes, particularly acquisition and transmission of sexually transmitted diseases (STDs) and poor birth outcomes. Vaginal flora have been found to cluster into a limited number of communities, although community structure is dynamic. Certain community types are more associated with poor reproductive outcomes and STDs; communities dominated by Lactobacillus species, particularly Lactobacillus crispatus, are most associated with vaginal health. Modifiable and nonmodifiable factors are strongly associated with community composition, including behavior, race or ethnicity, and hygiene. In this review, we describe the state of the science on the vaginal microbiome and its relationship to behavior, sexual health, and STDs, including determinants of the microbiome that go beyond an individual level.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Lewis FMT,Bernstein KT,Aral SOdoi
10.1097/AOG.0000000000001932subject
Has Abstractpub_date
2017-04-01 00:00:00pages
643-654issue
4eissn
0029-7844issn
1873-233Xpii
00006250-201704000-00008journal_volume
129pub_type
杂志文章,评审abstract:OBJECTIVE:Testing hemoglobin and hematocrit values in labor and delivery at term is a routine practice at many centers. This necessity was evaluated by comparing values obtained at 26-28 weeks versus those obtained at term. MATERIALS:This is a prospective, observational study. All patients at least 37 weeks presenting...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(01)01586-1
更新日期:2001-12-01 00:00:00
abstract::Mycotic cultures of 33 couples, in which the women had a diagnosis of chronic recurrent vulvovaginitis, were prepared from the oral cavity, the rectum, the vagina, and the male ejaculate. Reservoirs of infection were found in the oral cavities of 36% of the couples, the rectum in 33%, and the ejaculate in 15%. Prostat...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1987-06-01 00:00:00
abstract:OBJECTIVE:To examine the relationship between an obstetrician's delivery volume and a patient's risk for cesarean delivery. METHODS:This retrospective cohort study examined patient-level and obstetrician-level data between 2000 and 2012 at a large academic hospital. All laboring patients who delivered viable, liveborn...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000000473
更新日期:2014-10-01 00:00:00
abstract::We reviewed our experience with a policy of revising the estimated probability of an open neural tube defect for those cases in which maternal serum alpha-fetoprotein (MSAFP) was elevated and the ultrasound examination was normal. Assuming a sensitivity for the ultrasound diagnosis of neural tube defects of 90%, the r...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1988-02-01 00:00:00
abstract:BACKGROUND:Because of donor oocyte programs, women who previously were considered too old to successfully achieve conception and delivery can now bear children. To our knowledge, there have been no previous reports of pregnancy outcome in women over age 50 who conceived using donor oocytes. This study presents the preg...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1993-05-01 00:00:00
abstract:OBJECTIVE:To estimate an institution's specific fetal loss rate after a second-trimester genetic amniocentesis. METHODS:This is a retrospective cohort study using our prenatal diagnosis database for all pregnant women presenting for care between 1990 and 2006. We compared the fetal loss rate in women who underwent amn...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e318162eb53
更新日期:2008-03-01 00:00:00
abstract::The serum concentration of placental protein 12 was measured by radioimmunoassay in 111 apparently healthy pregnant women at 33 to 40 weeks, and the results were compared with those of 39 women with preeclampsia either with or without proteinuria at similar stages of pregnancy. Because the placental protein 12 levels ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1986-07-01 00:00:00
abstract:OBJECTIVE:To comprehensively review and critically assess the available gynecologic surgery venous thromboembolism prophylaxis literature and provide clinical practice guidelines. DATA SOURCES:MEDLINE and Cochrane databases from inception to July 2010. We included randomized controlled trials in gynecologic surgery po...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章,评审
doi:10.1097/AOG.0b013e318232a394
更新日期:2011-11-01 00:00:00
abstract::Recommendations for activity after obstetric and gynecologic procedures remain based on tradition and anecdote. After reviewing the current evidence base, guidelines, and practice for postdischarge instructions related to physical activity after the most common obstetric and gynecologic surgical procedures, we conclud...
journal_title:Obstetrics and gynecology
pub_type: 社论
doi:10.1097/AOG.0b013e3181b6f50d
更新日期:2009-10-01 00:00:00
abstract::Preoperative abdominopelvic computed tomography results and operative findings were compared in 52 patients undergoing second-look laparotomy to confirm tumor status. Seventeen true-negative, 22 false-negative, and 13 true-positive scans were found. The sensitivity was 0.38, specificity was 1.0, and diagnostic accurac...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1985-05-01 00:00:00
abstract:OBJECTIVE:To address the evolving trends in the choice of transabdominal or transcervical chorionic villus sampling (CVS) at a teaching hospital and to evaluate the influence of gestational age on the approach chosen. METHODS:We analyzed our CVS data base, which contained information from 1986-1991. The proportions of...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract:BACKGROUND:Vaginal evisceration can take place many years after vaginal surgery. CASE:An 87-year-old woman presented with evisceration of small bowel through the vagina, 15 years after she underwent a vaginal hysterectomy. On physical examination, her vital signs were normal. Forty centimeters of small bowel was visib...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(02)02336-0
更新日期:2003-05-01 00:00:00
abstract::A Clostridium perfringens infection is described in an 18-year-old primigravida following cesarean section at 43 weeks' gestation. Despite the ubiquitous distribution of these organisms, such infections are rarely encountered in obstetrics. Characteristics of these bacteria and appropriate diagnostic and therapeutic p...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1980-10-01 00:00:00
abstract::The rollover test is useful in predicting and identifying subjects developing hypertensive disorders of pregnancy. The mechanisms responsible for positive tests are unclear, but a greater release of pressor substances occurring in subjects with positive tests has been proposed. The authors measured and compared heart ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1984-04-01 00:00:00
abstract::A chemotherapeutic combination of bleomycin-adriamycin-cisplatin has been used to treat 21 consecutive patients with primary advanced or recurrent cervical carcinomas. Four complete (19.0%) and four partial remissions were recorded. The responding patients had significantly longer survival levels compared with the rem...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1984-02-01 00:00:00
abstract:OBJECTIVE:To compare the pharmacokinetics of vaginal and oral administration of the prostaglandin E1 analogue, misoprostol. METHODS:Twenty women received 400-micrograms doses of misoprostol either orally or as tablets placed in the vagina. Serum levels of principal metabolite, misoprostol acid, were measured at 7.5, 1...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/S0029-7844(97)00111-7
更新日期:1997-07-01 00:00:00
abstract::The authors describe a pregnancy complicated by rhesus sensitization and the May-Hegglin anomaly. The principal objective in caring for the patient was prevention of maternal and fetal hemorrhage. Transfusion of type-specific platelets corrected the patient's abnormal bleeding time. Cesarean section resulted in delive...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1985-03-01 00:00:00
abstract::Advances in the immunopathology of blistering diseases now provide increased accuracy in the diagnosis of herpes gestationis in pregnancy. Guidelines are presented in this review to determine the presence of the disease. Exogenous corticosteroids will effectively alleviate symptoms and prevent formation of new lesions...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1977-06-01 00:00:00
abstract::A new technique is presented for funipuncture under ultrasound guidance using a biopsy guide and a 20/25-gauge needle combination. The 20-gauge needle was used for uterine entry and the 25-gauge needle for the actual cord puncture. The method was used for sampling fetal blood in 262 pregnancies with 264 fetuses (two s...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract:OBJECTIVE:To examine the current patterns of care for women at high risk for delivery-related morbidity to inform discussions about the feasibility of this regionalized approach. METHODS:We performed a cross-sectional study and linked 2014 American Hospital Association survey and State Inpatient Database data from sev...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000003397
更新日期:2019-09-01 00:00:00
abstract::A double-blind study was carried out to compare the effect of submucous paracervical blockade using 12 mL 0.25% bupivacaine (55 women) to the effect of intramuscular injection of 75 mg meperidine (62 women) during the first stage of labor. All 117 were normal primiparous pregnancies. Seventy-eight percent of the women...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章
doi:
更新日期:1984-11-01 00:00:00
abstract:OBJECTIVE:To compare persistent ectopic pregnancy after laparoscopic salpingostomy versus salpingostomy at laparotomy for the treatment of intact ampullary ectopic pregnancy. METHODS:We reviewed the medical records of 157 patients who had undergone salpingostomy for intact ampullary ectopic pregnancy at Yale-New Haven...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1993-03-01 00:00:00
abstract::Nine pregnant women near term, with medical indications for internal monitoring during labor, were studied to determine the transmission of sound across maternal soft tissues during vibroacoustic stimulation with an electronic artificial larynx. A miniaturized hydrophone was placed transcervically at the level of the ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1992-06-01 00:00:00
abstract:OBJECTIVE:To report our experience with first-trimester screening for trisomy 21 by using the combination of nuchal translucency thickness and nasal bone assessment. METHODS:Pregnant women from a predominantly Latin American population consisting of patients at both low risk and high risk for chromosomal defects under...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/01.AOG.0000259311.87056.5e
更新日期:2007-05-01 00:00:00
abstract:OBJECTIVE:Currently, treatment of respiratory distress syndrome (RDS) of the preterm newborn incorporates exogenous surfactant administration. Because fetuses make breathing motions, we proposed that intra-amniotic administration of an exogenous surfactant, Exosurf, to the preterm rabbit fetus results in uptake of Exos...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1992-10-01 00:00:00
abstract::A review of 2 cases of 46,XY pure gonadal dysgenesis (Swyer's syndrome) is presented. In one, bilateral gonadoblastomas with dysgerminomas were found at the time of laparotomy for gonadal extirpation. The second case was of interest because of endometriosis on the mesosalpinx, an entity heretofore undescribed in pure ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/00006250-198003001-00020
更新日期:1980-03-01 00:00:00
abstract::The early detection of preterm labor and the prevention of preterm birth require special attention to early subtle signs and symptoms of preterm labor. The concept of "Braxton Hicks contractions" may negate these early signs and symptoms by falsely reassuring patients, thus encouraging them not to seek medical care pr...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1990-04-01 00:00:00
abstract:BACKGROUND:To facilitate extraction and avoid intra-abdominal spillage during laparoscopic removal of adnexal masses, various designs and sizes of endopouches (bags) have been used. We describe a simple technique using a special laparoscopic bag that requires no additional instruments to hold, open, or close the bag. ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVE:Elective repeat cesarean delivery at 37 or 38 weeks compared with 39 completed weeks of gestation is associated with adverse neonatal outcomes. We assessed whether delivery before 39 weeks is justifiable on the basis of decreased adverse maternal outcomes. METHODS:We conducted a cohort study of women with li...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0b013e3182078115
更新日期:2011-02-01 00:00:00
abstract::The hemodynamic effects of intravenously infused dihydralazine (incremental doses up to 125 micrograms per minute during 60 minutes) were studied in ten women with acute or superimposed severe preeclampsia. The intervillous and umbilical vein blood flow were measured before and during dihydralazine infusion with 133Xe...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1985-01-01 00:00:00