Abstract:
:Trypanosoma acomys (Stercoraria, Trypanosomatidae) was studied in the laboratory-bred spiny mouse Acomys cahirinus. Only trypomastigotes were found in peripheral blood, whereas the thymus of experimentally infected A. cahirinus showed amastigote syncytial reproductive forms whose nuclei of nuclei ranged from 2 to 128. These reproductive forms were detected 9-10 days after the i.p. injection of spiny mice with trypanosomes obtained from primary lung cultures. Transitional trypomastigote-like forms were observed in the thymus; no reproductive or diving forms were encountered in any other tissue, including blood. The course of the parasitemia in spiny mice inoculated i.p. with 1.2 x 10(6) parasites from 26- to 32-day-old cultures initiated from infected lungs was studied. A similar, characteristic pattern was observed in both male and female hosts. Four phases were recognized: latent, logarithmic, stationary, and decline. These phases ended on days 2, 14, 98, and 154 postinoculation, respectively. The decline phase was gradual and the parasites could not be detected by day 154 postinoculation. In contrast, inoculation from older cultures (35-50 days old) showed longer latent and logarithmic phases, a shorter stationary phase, and a sharp drop in parasite density during the decline phase; the parasites were not detected in the peripheral blood by 120 days postinoculation.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Abdallah MA,Abdel-Hafez SK,al-Yaman FMdoi
10.1007/BF00930969subject
Has Abstractpub_date
1989-01-01 00:00:00pages
439-43issue
6eissn
0932-0113issn
1432-1955journal_volume
75pub_type
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