Abstract:
:We report a case of congenital hypertrichosis and FOXN1 duplication. FOXN1 is a member of the forkhead box gene family, located on chromosome 17. Its function includes differentiation of epithelial cells and regulation of keratinocytes, especially hair keratins. Loss of function of these transcription factors leads to a disruption in hair growth. As far as we are aware, this is the first case of FOXN1 duplication associated with congenital hypertrichosis to be reported in the literature.
journal_name
Pediatr Dermatoljournal_title
Pediatric dermatologyauthors
Gilhooley E,Gormally S,Irvine A,Lynch SA,Collins Sdoi
10.1111/pde.13078subject
Has Abstractpub_date
2017-03-01 00:00:00pages
e77-e79issue
2eissn
0736-8046issn
1525-1470journal_volume
34pub_type
杂志文章abstract:BACKGROUND/OBJECTIVES:Bullous impetigo (BI) is a common dermatologic condition, particularly in children, yet confusion regarding its diagnosis and treatment persists. This study measured pediatricians' ability to diagnose and appropriately treat BI and explored factors that might influence pediatricians' accuracy in m...
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