Impact of major depressive disorder, distinct subtypes, and symptom severity on lifestyle in the BiDirect Study.

Abstract:

:The aim of this study was to examine associations of major depressive disorder (MDD), its distinct subtypes, and symptom severity with the individual lifestyle factors smoking, diet quality, physical activity, and body mass index as well as with a combined lifestyle index measuring the co-occurrence of these lifestyle factors. A sample of 823 patients with MDD and 597 non-depressed controls was examined. The psychiatric assessment was based on a clinical interview including the Mini International Neuropsychiatric Interview and the Hamilton Depression Rating Scale. Each lifestyle factor was scored as either healthy or unhealthy, and the number of unhealthy lifestyle factors was added up in a combined lifestyle index. Cross-sectional analyses were performed using alternating logistic regression and ordinal logistic regression, adjusted for socio-demographic characteristics. After adjustment, MDD was significantly associated with smoking, low physical activity, and overweight. Likewise, MDD was significantly related to the overall lifestyle index. When stratifying for subtypes, all subtypes showed higher odds for an overall unhealthier lifestyle than controls, but the associations with the individual lifestyle factors were partly different. Symptom severity was associated with the lifestyle index in a dose-response manner. In conclusion, patients with MDD represent an important target group for lifestyle interventions.

journal_name

Psychiatry Res

journal_title

Psychiatry research

authors

Rahe C,Khil L,Wellmann J,Baune BT,Arolt V,Berger K

doi

10.1016/j.psychres.2016.08.035

subject

Has Abstract

pub_date

2016-11-30 00:00:00

pages

164-171

eissn

0165-1781

issn

1872-7123

pii

S0165-1781(16)30604-7

journal_volume

245

pub_type

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