Abstract:
BACKGROUND:Worldwide, tuberculosis remains a major health concern, with an estimated 9.6 million people infected in the year 2014, of which one-third were women. Tuberculosis is estimated to be even more prevalent in pregnant women than the general population. To date there has been conflicting evidence on the maternal and neonatal complications of tuberculosis in pregnancy. OBJECTIVE:We sought to determine trends in the incidence of tuberculosis in pregnancy and to examine the associations between tuberculosis in pregnancy and maternal and fetal complications. STUDY DESIGN:We conducted a retrospective cohort study using the 2003 through 2011 Healthcare Cost and Utilization Project Nationwide Inpatient Sample. We identified hospital admissions during which women with and without tuberculosis delivered. The temporal patterns in incidence of tuberculosis were estimated, as were the rates of pulmonary and nonpulmonary tuberculosis. Multivariate logistic regression was used to examine the adjusted effects of tuberculosis on maternal and neonatal outcomes. RESULTS:During the study period, there were 7,772,999 births, of which 2064 were to women with tuberculosis, for an overall incidence of 26.6 per 100,000 births. From 2003 through 2011, there was an upward trend in the incidence of tuberculosis from 1.92-4.06 per 10,000 births (P < .0001), mostly due to increasing numbers of nonpulmonary tuberculosis. Compared with noncases, tuberculosis occurred with greater frequency in women who were 25-34 years of age and of Hispanic ethnicity. Significantly more women with tuberculosis had concurrent HIV. In addition, delivery hospitalizations with tuberculosis compared with those without tuberculosis were more likely to experience chorioamnionitis, preterm labor, postpartum anemia, blood transfusion, pneumonia, acute respiratory distress syndrome, and mechanical ventilation. Maternal mortality was significantly increased in women with tuberculosis. Congenital anomalies were higher among babies delivered to women with tuberculosis. CONCLUSION:The rate of tuberculosis in pregnancy is rising in the United States. Although this increase appears to be mostly due to nonpulmonary disease, there was also a high incidence of maternal respiratory complications, mortality, and postpartum obstetric morbidity.
journal_name
Am J Obstet Gynecoljournal_title
American journal of obstetrics and gynecologyauthors
El-Messidi A,Czuzoj-Shulman N,Spence AR,Abenhaim HAdoi
10.1016/j.ajog.2016.08.009subject
Has Abstractpub_date
2016-12-01 00:00:00pages
797.e1-797.e6issue
6eissn
0002-9378issn
1097-6868pii
S0002-9378(16)30574-9journal_volume
215pub_type
杂志文章abstract:OBJECTIVE:The purpose of this study was to assess endothelial dysfunction in women with preeclampsia by measuring endothelial microparticles. STUDY DESIGN:A case-control study was conducted on 20 women with preeclampsia and 20 healthy pregnant women as control subjects. Endothelial microparticles were measured by flow...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1067/s0002-9378(03)00469-1
更新日期:2003-08-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to summarize recent evidence regarding infection-associated preterm birth and to make appropriate recommendations. Antepartum treatment of lower genital tract infection or bacterial colonization has been found to reduce the incidence of preterm birth in the case of asymptomatic b...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2004.03.014
更新日期:2004-06-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate changes in cerebral blood perfusion and middle cerebral artery (MCA) Doppler in full-term small-for-gestational-age fetuses (SGA) and to explore their association with neonatal neurobehavioral performance. STUDY DESIGN:Frontal brain perfusion that was measured by fra...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2009.05.028
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:Although consensus guidelines on the management of cardiovascular disease in pregnancy reserve cesarean delivery for obstetric indications, there is a paucity of data to support this approach. OBJECTIVE:The objective of the study was to compare cardiovascular and obstetric morbidity in women with cardiovasc...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2019.07.019
更新日期:2020-01-01 00:00:00
abstract::Prostaglandin E2 is a powerful oxytocic agent that reliably initiates labor, even in the presence of an unripe cervix. The low incidence of fetomaternal complication contributes to its universal use. We report a rare case of uterine rupture after intracervical application of prostaglandin E2 gel. Thus far no prostagla...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(91)90094-8
更新日期:1991-08-01 00:00:00
abstract:OBJECTIVE:Our purpose was to study the effects of postmenopausal hormone replacement therapy on the uterus and uterine circulation. STUDY DESIGN:The study population consisted of 432 women, 58 to 59 years of age. Color Doppler ultrasonography with a transvaginal probe was used to measure the size of the uterus and the...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(93)90506-e
更新日期:1993-02-01 00:00:00
abstract:OBJECTIVE:This study was undertaken to evaluate the occurrence and management of mesh erosions in patients undergoing abdominal sacrocolpopexy. STUDY DESIGN:A retrospective chart review of the abdominal sacrocolpopexy procedure (n = 92) between 1997 and 2003 was performed. Patients with mesh erosion were identified. I...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2005.02.062
更新日期:2005-06-01 00:00:00
abstract::A robotic-assisted laparoscopic technique for transabdominal cerclage placement could offer improvements over the traditional laparoscopic approach. A gravid female with no vaginal portion of the cervix underwent a robotic-assisted laparoscopic cerclage at 12 weeks' gestation and ultimately delivered a healthy infant ...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2008.10.029
更新日期:2009-02-01 00:00:00
abstract::A study was made of the relationship of proton T1 relaxation times and stage of the menstrual cycle. Preliminary data show that these indicators of red blood cell hydration status may be useful as objective markers of premenstrual tension. ...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(85)90358-8
更新日期:1985-12-01 00:00:00
abstract:BACKGROUND:Preeclampsia (PE) affects 2-3% of all pregnancies and is a major cause of maternal and perinatal morbidity and mortality. The traditional approach to screening for PE is to use a risk-scoring system based on maternal demographic characteristics and medical history (maternal factors), but the performance of s...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2015.11.016
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:Our purpose was to determine whether elevated second-trimester human chorionic gonadotropin levels identify women likely to benefit from low-dose aspirin therapy. STUDY DESIGN:We evaluated second-trimester human chorionic gonadotropin levels obtained from healthy nulliparous women before screening for partic...
journal_title:American journal of obstetrics and gynecology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/0002-9378(95)91373-4
更新日期:1995-10-01 00:00:00
abstract:OBJECTIVE:We sought to determine the pregnancy and infant outcomes of women with gestational diabetes who attempted vaginal birth after previous cesarean delivery. STUDY DESIGN:We conducted a retrospective cohort study to compare women with gestational diabetes with matched control subjects without diabetes who attemp...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1067/mob.2001.115176
更新日期:2001-05-01 00:00:00
abstract::The effects of maternal hyperexcitability on the fetus were studied in 17 baboons. In the period of agitation, induced by stressful stimulus such as exposure to bright light or by clamping of the toe, the mother exhibited an increase in arterial blood pressure and, in some instances, arrhythmia. These changes were acc...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(16)33032-0
更新日期:1979-06-01 00:00:00
abstract::We examined the effect of sustained hypoxemia with progressive acidemia on pituitary-adrenal endocrine function (adrenocorticotropic hormone, cortisol) and on adrenal blood flow in fetal sheep. Hypoxemia was induced by the maternal sheep breathing a gas mixture containing 9% oxygen, with 3% carbon dioxide added. Induc...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(86)90169-9
更新日期:1986-12-01 00:00:00
abstract:OBJECTIVE:The prototypic long pentraxin pentraxin 3 is a new candidate marker for inflammatory conditions reflecting the involvement of the vascular bed. Endothelial dysfunction is a prominent feature of preeclampsia as a result of excessive maternal systemic inflammation. We investigated pentraxin 3 levels in preeclam...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2005.11.018
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to determine the effect of an obstetrics patient safety program on staff safety culture. STUDY DESIGN:We implemented (1) obstetrics patient safety nurse, (2) protocol-based standardization of practice, (3) crew resource management training, (4) oversight by a patient safety comm...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2010.11.004
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Surgical abortion is a generally safe procedure. Obesity is a known risk factor for complications in other surgical procedures, but insufficient information exists to determine the effects of increasing body mass index on the risk of surgical abortions. OBJECTIVE:The purpose of this study was to determine w...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2017.10.018
更新日期:2018-02-01 00:00:00
abstract::Retirement of obstetrician-gynecologists is becoming a matter of increasing concern in light of an expected shortage of practicing physicians. Determining a retirement age is often complex. We address what constitutes a usual retirement age range from general clinical practice for an obstetrician-gynecologist, compare...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/j.ajog.2015.03.027
更新日期:2015-09-01 00:00:00
abstract::A total of 679 fetal monitoring records were carefully reviewed in order to determine the incidence of occurrence of late and variable deceleration patterns with respect to advancing gestational age. No statistically significant increase in occurrence of these patterns could be detected in gestations that progressed b...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(77)90498-7
更新日期:1977-02-15 00:00:00
abstract::Vasomotor symptoms after menopause are multifactorial in origin but result primarily from the loss of estrogen as ovarian function ceases. Although hot flushes typically last for 0.5 to 5.0 years after natural menopause, they may persist for as long as 15 years in a small percentage of postmenopausal women. In contras...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章,评审
doi:10.1016/s0002-9378(99)70725-8
更新日期:1999-03-01 00:00:00
abstract::Intervillous placental blood flow and indices of fetal heart rate variability were measured from seven healthy pregnant women in the last trimester of pregnancy, once before and twice after smoking one cigarette. A blood flow reduction was observed in seven, a rise in five, and no change in two measurements. When inte...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(83)90975-4
更新日期:1983-08-15 00:00:00
abstract:OBJECTIVE:The purpose of this study was to describe patient preferences for uterine preservation and hysterectomy in women with pelvic organ prolapse symptoms and to describe predictors of preference for uterine preservation. STUDY DESIGN:This multicenter, cross-sectional study evaluated patient preferences for uterin...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ajog.2013.08.003
更新日期:2013-11-01 00:00:00
abstract::A case of ovarian and systemic sarcoidosis with mucinous cystadenoma coexisting in the same ovary is described. This association has not been previously reported. The differentiation of systemic sarcoidosis from metastatic spread of ovarian cancer and from sarcoid-like reactions in regional lymph nodes of tumors is di...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(90)90038-9
更新日期:1990-05-01 00:00:00
abstract::Posterior vaginal repair is often poorly understood and ineffectively performed. The goals of reconstructive surgery emphasize relief of symptoms and restoration of normal anatomic relationships and of function. A useful method to preoperatively determine posterior vaginal wall weakness is outlined along with a surgic...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(91)90503-j
更新日期:1991-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to determine whether any association exists between preeclampsia and circulating platelet activating factor levels. STUDY DESIGN:We performed a cross-sectional observational study of circulating platelet activating factor concentrations in nonpregnant women, normotensive pregnant wo...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1067/mob.2000.108894
更新日期:2000-10-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to characterize the innervation of the human female levator ani muscles. STUDY DESIGN:Detailed dissections of the peripheral innervation of the iliococcygeal, pubococcygeal, puborectal, and coccygeal muscles were performed in 12 fresh-frozen female cadavers (aged, 32-100 years...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1067/mob.2002.124844
更新日期:2002-07-01 00:00:00
abstract::After treatment with human gonadotropins, 289 anovulatory women with apparently normal fallopian tubes became pregnant 379 times. Ten ectopic pregnancies in nine women were diagnosed, for an incidence of 2.7% of all conceptions. All the ectopic pregnancies were found in the fallopian tubes. Four patients had also an i...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(82)90006-0
更新日期:1982-08-01 00:00:00
abstract::Capillary hydrostatic pressure has been calculated in normal pregnancy and preeclampsia. In humans, capillary hydrostatic pressure cannot be measured directly but may be calculated when the colloid osmotic pressure in plasma and interstitial fluid and interstitial fluid hydrostatic pressure are known (Starling equatio...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0002-9378(87)80355-1
更新日期:1987-07-01 00:00:00
abstract::To our knowledge, placental transfer of pentamidine has not been previously studied in vivo. In the present study, the pharmacokinetics of pentamidine were analyzed in late gestation (18 days) among Sprague-Dawley rats. Pentamidine's kinetics were assessed in the following maternal compartments over a 12-hour period i...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(91)90541-x
更新日期:1991-03-01 00:00:00
abstract::The ability to predict myometrial invasion by endometrial adenocarcinoma is useful for preoperative treatment purposes. The presence of stromal invasion is one possible method of predicting myometrial invasion, but criteria for the presence of stromal invasion have been lacking. Recently, criteria for its detection we...
journal_title:American journal of obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/0002-9378(84)90283-7
更新日期:1984-05-01 00:00:00