The antibiotics of choice for the treatment of melioidosis in Indian set up.

Abstract:

:Therapeutic options for the treatment of melioidosis caused by Burkholderia pseudomallei are limited due to the inherent resistance conferred by this pathogen to various groups of antibiotics. Witnessing an increase in the number of microbiological culture-confirmed cases of melioidosis at our settings in the past few years, we undertook this study to estimate the minimum inhibitory concentrations of clinical isolates of B. pseudomallei against the four commonly employed antimicrobial agents in the patient management at our settings, namely, ceftazidime, meropenem, trimethoprim-sulfamethoxazole and doxycycline. All isolates were susceptible to the antibiotics tested, except for one isolate which showed resistance to doxycycline (minimum inhibitory concentration [MIC]: 32 μg/ml). MIC50 and 90 for all the four antibiotics were estimated. From this study, we conclude that the clinical isolates of B. pseudomallei from the southern part of India are well susceptible to the commonly employed antimicrobial agents for therapy.

journal_name

Indian J Med Microbiol

authors

Shaw T,Tellapragada C,Eshwara VK,Bhat HV,Mukhopadhyay C

doi

10.4103/0255-0857.188340

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

353-4

issue

3

eissn

0255-0857

issn

1998-3646

pii

IndianJMedMicrobiol_2016_34_3_353_188340

journal_volume

34

pub_type

杂志文章
  • Serological diagnosis of dengue in laboratory practice in Kolkata.

    abstract:PURPOSE:To find out the most suitable serological investigative procedures to diagnose dengue cases effectively in the laboratory practice identifying primary and secondary cases as well as period of suffering. MATERIALS AND METHODS:Dengue suspected cases sent to the laboratory in 2012 in central Kolkata by the local ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.136563

    authors: Bhattacharya N,Mukherjee H,Naskar R,Talukdar S,Das G,Pramanik N,Hati AK

    更新日期:2014-07-01 00:00:00

  • Learning from an outbreak: ESBL- the essential points.

    abstract::Extended spectrum beta-lactamase (ESBL) producing strains of Klebsiella pneumoniae have emerged as important nosocomial pathogens. The present report describes an outbreak of ESBL positive K. pneumoniae in a neonatal intensive care unit of a tertiary care center in southern India. The clinical and microbiological sign...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Shanmuganathan C,Ananthakrishnan A,Jayakeerthi SR,Kanungo R,Kumar A,Bhattacharya S,Badrinath S

    更新日期:2004-10-01 00:00:00

  • Erratum: Endemic Indian clones of Klebsiella pneumoniae harbouring New Delhi metallo beta lactamase 1 on a hybrid plasmid replicon type: A case of changing New Delhi metallo beta lactamase plasmid landscapes in India?

    abstract::[This corrects the article DOI: 10.4103/0255-0857.188314.]. ...

    journal_title:Indian journal of medical microbiology

    pub_type: 已发布勘误

    doi:10.4103/0255-0857.195384

    authors:

    更新日期:2016-10-01 00:00:00

  • Blood culture gram stain, acridine orange stain and direct sensitivity-based antimicrobial therapy of bloodstream infection in patients with trauma.

    abstract:PURPOSE:The purpose of this study was to ascertain if the simple practice of Gram stain, acridine orange stain and direct sensitivity determination of positive blood culture bottles could be used to guide early and appropriate treatment in trauma patients with clinical suspicion of sepsis. The study also aimed to evalu...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.62491

    authors: Behera B,Mathur P,Gupta B

    更新日期:2010-04-01 00:00:00

  • Detection of porcine rotavirus from tissue and faecal specimens.

    abstract::Porcine small intestinal sub-mucosa is a cell-free collagen matrix that has demonstrated its ability as a scaffold material. Transplantation poses special hazards because grafted tissues and organs transmit pathogens efficiently, especially viruses. Rotavirus is thought to be confined to the intestine, causing acute d...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.49430

    authors: Prabha S,Verghese S

    更新日期:2009-04-01 00:00:00

  • Chikungunya fever: a re-emerging viral infection.

    abstract::Chikungunya (CHIK) fever is a re-emerging viral disease characterized by abrupt onset of fever with severe arthralgia followed by constitutional symptoms and rash lasting for 1-7 days. The disease is almost self-limiting and rarely fatal. Chikungunya virus (CHIKV) is a RNA virus belonging to family Togaviridae, genus ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章,评审

    doi:10.4103/0255-0857.38850

    authors: Chhabra M,Mittal V,Bhattacharya D,Rana U,Lal S

    更新日期:2008-01-01 00:00:00

  • Necrotizing (malignant) otitis externa: an unusual localization of mucormycosis.

    abstract::Malignant otitis externa (MOE) is a severe infection of external auditory canal and skull base. A 17-year-old diabetic girl was admitted with diabetic ketoacidosis. Cellulitis of her right ear occurred on the second day of hospitalization and a black necrotic scar in the same region appeared on the next day. The lesio...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.29390

    authors: Tuzcu A,Bahceci M,Celen MK,Kilinc N,Ozmen S

    更新日期:2006-10-01 00:00:00

  • Plasmid mediated quinolone resistance determinants qnr, aac(6')-Ib-cr, and qep in ESBL-producing Escherichia coli clinical isolates from Egypt.

    abstract:PURPOSE:To characterize the prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6')-Ib-cr and qep in extended-spectrum β-lactamase (ESBL) -producing E. coli and to determine the association of these determinants with CTX-M group in Cairo, Egypt. MATERIALS AND METHODS:MICs of 15 antimicrobial agen...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.103766

    authors: Hassan WM,Hashim A,Domany R

    更新日期:2012-10-01 00:00:00

  • Salmonella enteritidis meningitis - a case report.

    abstract::A male infant admitted with pyogenic meningitis with protein energy malnutrition developed fatal infection due to Salmonella enteritidis. The same organism was isolated from CSF and blood cultures. ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Varaiya A,Saraswathi K,Tendolkar U,De A,Shah S,Mathur M

    更新日期:2001-07-01 00:00:00

  • ESBL - from petri dish to the patient.

    abstract::Treatment of extended spectrum beta-lactamase (ESBL) producing strains of Enterobacteriaceae has emerged as a major challenge in hospitalised as well as community based patients. Infections due to ESBL producers range from uncomplicated urinary tract infection to life threatening sepsis. Although several reviews have ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章,评审

    doi:10.4103/0255-0857.19889

    authors: Bhattacharya S

    更新日期:2006-01-01 00:00:00

  • Vibrionaceae from cases of acute diarrhoea and their antimicrobial sensitivity pattern - a five year prospective study.

    abstract::Over a five year period, stool samples were screened for Vibrionaceae from cases of acute diarrhoea, to study their isolation rate and their antimicrobial sensitivity pattern. All the isolates were identified by standard laboratory techniques. A total of 323 species belonging to Vibrionaceae were isolated from 4492 st...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Mathur M,De A,Saraswathi K,Varaiya A,Athalye S

    更新日期:2003-07-01 00:00:00

  • Simple and economical method for speciation and resistotyping of clinically significant coagulase negative staphylococci.

    abstract::An attempt was made to speciate 102 clinically significant isolates of coagulase negative staphylococci (CoNS) by a practical scheme adapted from various references. This scheme utilizes slide and tube coagulase test, urease test ornithine decarboxylase, novobiocin susceptibility and aerobic acid from mannose for assi...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Goyal R,Singh NP,Kumar A,Kaur I,Singh M,Sunita N,Mathur M

    更新日期:2006-07-01 00:00:00

  • Evaluation of biphasic culture system for mycobacterial isolation from the sputum of patients with pulmonary tuberculosis.

    abstract::Mycobacterial diseases continue to cause high morbidity and mortality. Isolation, identification and sensitivity testing form the backbone of laboratory investigations. M. tuberculosis isolation needs 6-8 weeks on conventional egg containing media. For rapid isolation various methods have been evaluated. We evaluated ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.16050

    authors: Ghatole M,Sable C,Kamale P,Kandle S,Jahagirdar V,Yemul V

    更新日期:2005-04-01 00:00:00

  • Eumycetoma pedis due to Exophiala jeanselmei.

    abstract::A case of eumycetoma of foot in an 8-year old male child was clinically diagnosed as chronic osteomyelitis and was microbiologically confirmed as eumycetoma. The case is being reported for its uncommon clinical presentation and etiological agent, Exophiala jeanselmei. The patient recovered completely after treatment w...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.32726

    authors: Capoor MR,Khanna G,Nair D,Hasan A,Rajni,Deb M,Aggarwal P

    更新日期:2007-04-01 00:00:00

  • Trichosporon asahii as an emerging etiologic agent of disseminated trichosporonosis: a case report and an update.

    abstract:PURPOSE:To report a fatal case of disseminated trichosporonosis caused by Trichosporon asahii in a patient with acute myeloblastic leukemia (AML) and to present an update on systemic trichosporonosis with special reference to India. METHODS:The diagnosis was based on repeated demonstration of budding yeast cells and a...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Chowdhary A,Ahmad S,Khan ZU,Doval DC,Randhawa HS

    更新日期:2004-01-01 00:00:00

  • Asymptomatic bacteriuria in school going children.

    abstract:PURPOSE:The present study was undertaken to determine the prevalence of asymptomatic bacteriuria in school going children of different age groups and sex and to isolate the organisms responsible for asymptomatic bacteriuria and to know their antimicrobial susceptibility pattern. METHODS:A total of 1817 school children...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Kumar CS,Jairam A,Chetan S,Sudesh P,Kapur I,Srikaramallya.

    更新日期:2002-01-01 00:00:00

  • Fusarium: The versatile pathogen.

    abstract::Fusarium is an emerging human opportunistic pathogen of growing importance, especially among immunosuppressed haematology patients due to an increased incidence of disseminated infections over the past two decades. This trend is expected only to continue due to the advances in medical and surgical technologies that wi...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章,评审

    doi:10.4103/ijmm.IJMM_16_24

    authors: Tupaki-Sreepurna A,Kindo AJ

    更新日期:2018-01-01 00:00:00

  • Demographic profile of healthy children with nasopharyngeal colonisation of Streptococcus pneumoniae: A research paper.

    abstract:BACKGROUND:Pneumonia is a preventable cause of mortality in children. Streptococcus pneumoniae colonising the nasopharynx of healthy children can cause invasive diseases and the serotype distribution of colonisation isolates should be an indicator of invasive disease, antibiotic resistance profiles, and potential vacci...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/ijmm.IJMM_15_347

    authors: Raman R,Sankar J,Putlibai S,Raghavan V

    更新日期:2017-10-01 00:00:00

  • Rising trend of antimicrobial resistance among Neisseria gonorrhoeae isolates and the emergence of N. gonorrhoeae isolate with decreased susceptibility to ceftriaxone.

    abstract:CONTEXT:Gonorrhoea is one of the most common sexually transmitted infections (STI) in developing countries and is a global health problem. AIMS:To analyze the trend of antimicrobial susceptibility of Neisseria gonorrhoeae isolates over the years, in a tertiary care hospital of North India. SETTINGS AND DESIGN:The stu...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.148374

    authors: Bharara T,Bhalla P,Rawat D,Garg VK,Sardana K,Chakravarti A

    更新日期:2015-01-01 00:00:00

  • An ocular cysticercosis case: Caused by Asian genotype of Taenia solium.

    abstract::An ocular cysticercosis case of a 42-year-old male, who presented with anterior uveitis is being reported. Microscopical examination of the cyst revealed presence of only one hooklet suggestive of T. solium cysticercus. Mitochondrial DNA analysis confirmed it to be T. solium cysticercus of Asian genotype. This is the ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.167319

    authors: Sharma M,Beke N,Khurana S,Bhatti HS,Sehgal R,Malla N

    更新日期:2015-10-01 00:00:00

  • Prevalence and antibiotic susceptibility of thermophilic Campylobacters from sources implicated in horizontal transmission of flock colonisation.

    abstract::Thermophilic Campylobacter are commonly associated with poultry as commensals of the avian gut and are the causative agent responsible for human Campylobacteriosis. This study aimed to establish the prevalence of Campylobacter spp. from environmental sources that have previously been implicated as sources of horizonta...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.142259

    authors: Parkar S,Sachdev D,Kapadnis B

    更新日期:2014-10-01 00:00:00

  • Detection of bacterial growth in blood components using oxygen consumption as a surrogate marker in a tertiary oncology setup.

    abstract::Microbiological contamination of blood and blood products is a well-recognised transfusion risk. This study was performed in the blood bank of our oncology centre, with an objective to detect bacterial contamination in our blood products using oxygen consumption as a surrogate marker [Pall Enhanced Bacterial Detection...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.96695

    authors: Chavan PD,Bhat VG,Ojha S,Kelkar RS,Rajadhyaksha SB,Marathe AN

    更新日期:2012-04-01 00:00:00

  • Trends in antimicrobial susceptibility of Salmonella Typhi from North India (2001-2012).

    abstract:PURPOSE:Enteric fever is endemic in India with Salmonella Typhi being the major causative agent. Antibiotic therapy constitutes the mainstay of management. The present study was undertaken to find the susceptibility profile of Salmonella enterica var Typhi (S. Typhi) blood isolates in a tertiary care hospital between J...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.129799

    authors: Singhal L,Gupta PK,Kale P,Gautam V,Ray P

    更新日期:2014-04-01 00:00:00

  • Nanotechnology: a new frontier in virus detection in clinical practice.

    abstract::Researchers are expanding the applications of nanotechnology in the field of medicine since mid-2000. These technologies include nanoarrays, protein arrays, nanopore technology, nanoparticles as a contrivance in immunoassays and nanosensors, among others. Nanobiotechnologies are clinically applicable and possess the p...

    journal_title:Indian journal of medical microbiology

    pub_type: 社论,评审

    doi:

    authors: Abraham AM,Kannangai R,Sridharan G

    更新日期:2008-10-01 00:00:00

  • 16S rRNA PCR for differentiation of pathogenic and non-pathogenic leptospira isolates.

    abstract:PURPOSE:To determine the risk factors, microbiological features, clinical features and other epidemiological characteristics of Nocardia keratitis seen at a tertiary eye care centre in south India. METHODS:We evaluated 31 patients with Nocardia keratitis seen over two years, from September 1999 to September 2001. Corn...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Shukla J

    更新日期:2003-01-01 00:00:00

  • Detection of opportunistic DNA viral infections by multiplex PCR among HIV infected individuals receiving care at a tertiary care hospital in South India.

    abstract:PURPOSE:Opportunistic viral infections cause increased morbidity and mortality among human immunodeficiency virus (HIV) infected individuals, especially those who are not on antiretroviral treatment. Early diagnosis of these opportunistic viruses will be able to reduce the risk of disease progression with appropriate i...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.53202

    authors: Sachithanandham J,Ramamurthy M,Kannangai R,Daniel HD,Abraham OC,Rupali P,Pulimood SA,Abraham AM,Sridharan G

    更新日期:2009-07-01 00:00:00

  • Vertebro-cerebral cryptococcosis mimicking tuberculosis: a diagnostic dilemma in countries with high burden of tuberculosis.

    abstract::We report a case of a 30-year-old immunocompetent man with disseminated cryptococcosis who was initially treated with antitubercular therapy due to clinical and radiological diagnosis of vertebro-cerebral tuberculosis. The diagnosis of Cryptococcus infection was made due to incidental isolation of this fungus from blo...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.96715

    authors: Gupta R,Kushwaha S,Behera S,Jaiswal A,Thakur R

    更新日期:2012-04-01 00:00:00

  • Cutaneous cryptococcosis among HIV infected patients.

    abstract::Five patients with HIV associated cutaneous cryptococcal infection are reported. ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:

    authors: Vasanthi S,Padmavathy BK,Gopal R,Sundaram RS,Manoharan G

    更新日期:2002-07-01 00:00:00

  • Ethics in biotechnology and biosecurity.

    abstract::Great advances in technology produce unique challenges. Every technology also has a dual use, which needs to be understood and managed to extract maximum benefits for mankind and the development of civilization. The achievements of physicists in the mid-20th century resulted in the nuclear technology, which gave us th...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章,评审

    doi:10.4103/0255-0857.90155

    authors: Jameel S

    更新日期:2011-10-01 00:00:00

  • Elizabethkingia meningoseptica: an emerging pathogen causing meningitis in a hospitalized adult trauma patient.

    abstract::A 23-year-old male patient who was a follow-up case of neurosurgery presented to our emergency department with a history of high-grade fever and clinical features of meningitis for 1 week. The cerebrospinal fluid (CSF) was sent to our laboratory for culture. The culture demonstrated growth of 1-2 mm in diameter light ...

    journal_title:Indian journal of medical microbiology

    pub_type: 杂志文章

    doi:10.4103/0255-0857.115653

    authors: Tak V,Mathur P,Varghese P,Misra MC

    更新日期:2013-07-01 00:00:00