当前位置： SCI文献检索 > EUROPEAN RADIOLOGY期刊下所有文献 > 3D-black-blood 3T-MRI for the diagnosis of thoracic large vessel vasculitis: A feasibility study.

3D-black-blood 3T-MRI for the diagnosis of thoracic large vessel vasculitis: A feasibility study.

Abstract：

OBJECTIVES:To evaluate the feasibility of T1w-3D black-blood turbo spin echo (TSE) sequence with variable flip angles for the diagnosis of thoracic large vessel vasculitis (LVV). METHODS:Thirty-five patients with LVV, diagnosed according to the current standard of reference, and 35 controls were imaged at 3.0T using 1.2 × 1.3 × 2.0 mm3 fat-suppressed, T1w-3D, modified Volumetric Isotropic TSE Acquisition (mVISTA) pre- and post-contrast. Applying a navigator and peripheral pulse unit triggering (PPU), the total scan time was 10-12 min. Thoracic aorta and subclavian and pulmonary arteries were evaluated for image quality (IQ), flow artefact intensity, diagnostic confidence, concentric wall thickening and contrast enhancement (CWT, CCE) using a 4-point scale. RESULTS:IQ was good in all examinations (3.25 ± 0.72) and good to excellent in 342 of 408 evaluated segments (83.8 %), while 84.1 % showed no or minor flow artefacts. The interobserver reproducibility for the identification of CCE and CWT was 0.969 and 0.971 (p < 0.001) with an average diagnostic confidence of 3.47 ± 0.64. CCE and CWT were strongly correlated (Cohen's k = 0.87; P < 0.001) and significantly more frequent in the LVV-group (52.8 % vs. 1.0 %; 59.8 % vs. 2.4 %; P < 0.001). CONCLUSIONS:Navigated fat-suppressed T1w-3D black-blood MRI with PPU-triggering allows diagnosis of thoracic LVV. KEY POINTS:• Cross-sectional imaging is frequently applied in the diagnosis of LVV. • Navigated, PPU-triggered, T1w-3D mVISTA pre- and post contrast takes 10-12 min. • In this prospective, single-centre study, T1w-3D mVISTA accurately depicted large thoracic vessels. • T1w-3D mVISTA visualized CWT/CCW as correlates of mural inflammation in LVV. • T1w-3D mVISTA might be an alternative diagnostic tool without ionizing radiation.

journal_name

Eur Radiol

journal_title

European radiology

authors

Treitl KM,Maurus S,Sommer NN,Kooijman-Kurfuerst H,Coppenrath E,Treitl M,Czihal M,Hoffmann U,Dechant C,Schulze-Koops H,Saam T

doi

10.1007/s00330-016-4525-x

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

2119-2128

issue

eissn

0938-7994

issn

1432-1084

pii

10.1007/s00330-016-4525-x

journal_volume

pub_type

杂志文章

在线工具

3D-black-blood 3T-MRI for the diagnosis of thoracic large vessel vasculitis: A feasibility study.