Abstract:
OBJECTIVE:The aims of current study were to determine whether childhood maltreatment contributes to the occurrence of major depressive disorder (MDD) with bipolarity or suicidality. METHODS:In total, 132 outpatients diagnosed with MDD between 2014 and 2015 on the medical records were included. The subjects were divided into two groups according to the presence of childhood maltreatment (CM group) and no childhood maltreatment (NCM group). Depression severity and bipolarity were identified using Beck Depression Inventory (BDI) and the Korean version of Mood Disorder Questionnaire (K-MDQ) respectively on the medical records. In addition, the baseline loud dependence of auditory evoked potentials of 36 patients on medical records were analyzed. RESULTS:The mean total BDI, BDI item 9 (suicide ideation), and total K-MDQ score were significantly higher in the CM group than the NCM group. The number of subjects with bipolarity was significantly higher in the CM than in the NCM group. Furthermore two thirds subjects experienced the significant maltreatment during childhood. The central serotonergic activity of the CM group was also lower than that of the NCM group. CONCLUSION:The findings of this study support that there is a relationship between childhood maltreatment and bipolarity or suicidality in patients with MDD.
journal_name
Psychiatry Investigjournal_title
Psychiatry investigationauthors
Park YMdoi
10.4306/pi.2017.14.2.136subject
Has Abstractpub_date
2017-03-01 00:00:00pages
136-140issue
2eissn
1738-3684issn
1976-3026journal_volume
14pub_type
杂志文章abstract::Transcranial direct current stimulation (tDCS), a non-invasive neuromodulation technique, has been increasingly used to treat bipolar depression. Researchers recently noticed the risk of tDCS-emergent mania/hypomania in depressed patients and started to evaluate this risk by launching a meta-analysis. Here we present ...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.08.11.1
更新日期:2018-09-01 00:00:00
abstract:OBJECTIVE:Adjustment disorder (ADJ) is a common diagnosis. However, it is difficult to distinguish ADJ from other major Axis I disorders, such as major depressive disorder (MDD). The aim of this study was to determine the distinguishing neurophysiological characteristics between ADJ and MDD using quantitative analysis ...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2013.10.1.62
更新日期:2013-03-01 00:00:00
abstract:OBJECTIVE:Type D personality can be regarded as a promising cardiovascular risk marker that has been repeatedly linked to relevant indicators of mental health, quality of life, morbidity, and mortality in cardiac patients. Heart rate variability (HRV) is a non-invasive technology that can provide information regarding ...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2015.12.2.197
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:The economic crisis and the implementation of austerity measures in Greece lead to significant socioeconomic changes. The effects of the crisis were mainly felt by the Greek population during the years 2011 and 2012. This study aimed to investigate the impact of Greece's economic crisis on the seasonality of ...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2017.14.1.16
更新日期:2017-01-01 00:00:00
abstract:OBJECTIVE:Electrophysiological studies, which are mostly focused on afferent pathway, have proven that auditory processing deficits exist in patients with schizophrenia. Nevertheless, reports on the suppressive effect of efferent auditory pathway on cochlear outer hair cells among schizophrenia patients are limited. Th...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2016.13.1.82
更新日期:2016-01-01 00:00:00
abstract::Major depressive disorder is often resistant to antidepressant treatment. Repetitive transcranial magnetic stimulation (rTMS) has been used in treatment-resistant depression (TRD). Known adverse events of rTMS include transient headache, local pain, syncope, seizure induction, and hypomania induction. This report outl...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2016.13.4.468
更新日期:2016-07-01 00:00:00
abstract:OBJECTIVE:The purpose of this study is to examine the relationship between substance use and depressive symptoms in a cohort of Koreans aged 45 years and older from a large, population-based study. Using the 2006 Korean Longitudinal Study of Aging, we estimated the prevalence of depressive symptoms and its association ...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2014.11.3.272
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:We tested for association of the catechol-O-methyltransferase (COMT) Val(158)-Met (rs4680) polymorphism with attention-deficit hyperactivity disorder (ADHD) using family-based test in Korean trios. METHODS:A total of 181 subjects with ADHD along with both of their biological parents were recruited from Unive...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2015.12.4.563
更新日期:2015-10-01 00:00:00
abstract::Obesity has become a major public health problem over the past two decades. Non-surgical management of obesity does not often achieve its long term goals. Surgical treatment is roaring in popularity because of dramatic and durable results. However, outcomes from bariatric surgery have become a significant area of scru...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2015.12.1.152
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVE:Coping can be defined as the reactions to harm or distress individuals take to reduce stress. This study aimed to determine how an individual's temperament and character is correlated with the person's main coping method. METHODS:The Korean version of the Ways of Coping Questionnaire and Temperament and Char...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.0084
更新日期:2020-01-01 00:00:00
abstract:Objective:The anti-epileptogenic drug levetiracetam has anticonvulsant and anti-epileptogenesis effects. Synergy between cell death and inflammation can lead to increased levels of apoptosis inhibitory factors and brain-derived neurotrophic factor, aberrant neurogenesis and extended axon sprouting. Once hyperexcitation...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2017.14.6.844
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:Serotonin-1A receptors (5-HTR1A) is suggested to be involved in the etiology of several psychiatric disorders including panic disorder (PD). A few imaging studies have suggested the alterations of the cingulum bundle in PD. The objective of this study is to examine the structural changes of cingulum related t...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2013.10.4.399
更新日期:2013-12-01 00:00:00
abstract:OBJECTIVE:Although neuroimaging studies have shown volumetric reductions, such as the anterior cingulate, prefrontal cortices, and hippocampus in patients with major depressive disorder (MDD), few studies have investigated the volume of or shape alterations in the subcortical regions and the brainstem. We hypothesized ...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2020.0025
更新日期:2020-05-01 00:00:00
abstract:OBJECTIVE:Continuous performance tests (CPTs) are frequently used in clinical practice to assess the attentiveness of ADHD children. Although most CPTs do not categorize T scores by intelligence, there is great diversity of opinion regarding the interrelation between intelligence and CPT performance. This study aimed t...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2011.8.3.227
更新日期:2011-09-01 00:00:00
abstract:Objective:Research has shown that intranasal oxytocin affects social cognition and behavior; however, its effects vary based on social context, individual characteristics and dose. The present study aimed to determine effective dose of oxytocin spray on emotion recognition in healthy Korean males. Methods:The study fo...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.02.19
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:A defense mechanism is an automatic psychological process necessary for successful adaptation. It reflects adaptive capacity. The purpose of this study is to explore the relationship between the adaptation ability of individuals who face mandatory military service and the pattern of defense mechanisms. METHO...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.11.07
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:Idiopathic Parkinson's disease (IPD) is a chronic progressive neurodegenerative movement disorder characterized by motor and non-motor symptoms that affects patients' quality of life and caregiver burden. The aim of our study was to assess the caregiver burden (CB) in early and late stages of disease and to s...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.02.20
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:To examine the reliability and validity of the self-report Korean version of Strengths and Difficulties Questionnaire (SDQ-Kr) in the community sample. METHODS:The SDQ-Kr was administered to a large sample of school children and adolescents (n=2814) and youth attendees of a psychiatric clinic (n=385) aged 11...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2015.12.4.491
更新日期:2015-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to perform validity and reliability examination of the Turkish form of Acceptance and Action Diabetes Questionnaire, and to investigate whether this scale is a measurement tool for evaluation of psychological flexibility levels in a sample of patients with diabetes in Turkey. METHODS...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.02.26.2
更新日期:2019-06-01 00:00:00
abstract::I report here an elderly woman receiving perphenazine together with terbinafine. After 1 week of terbinafine treatment she experienced extrapyramidal symptoms and, in particular, akathisia. Her symptoms did not disappear for 6 weeks, and so at 2 weeks prior to this most recent admission she had stopped taking terbinaf...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2012.9.4.422
更新日期:2012-12-01 00:00:00
abstract::Severe physical injury is a leading cause of posttraumatic syndrome (PTS). This is to develop a biomarker-based diagnostic algorithm for posttraumatic syndrome (BioPTS) study. This is a 2-year longitudinal cohort study assessing patients who were hospitalized beginning in 2015 at Chonnam National University Hospital i...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2017.14.4.513
更新日期:2017-07-01 00:00:00
abstract::Hallervorden-Spatz disease (HSD) is a rare autosomal-recessive hereditary disorder characterized by the early onset of progressive movement alterations, including dystonia, rigidity, choreoathetosis, and mental deterioration. HSD is also associated with a variety of psychiatric symptoms, primarily depression and menta...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2009.6.3.226
更新日期:2009-09-01 00:00:00
abstract:OBJECTIVE:The aim of this study is to determine the dose-response relationship between physical activity and anxiety symptoms. METHODS:We included data of 124,434 participants who had comprehensive health-screening examinations from January 1st, 2012, to December 31st, 2016, in Kangbuk Samsung Hospital, Seoul and Suwo...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.0078
更新日期:2020-01-01 00:00:00
abstract:OBJECTIVE:This study assessed the associations of the abnormal brain activation and functional connectivity (FC) during memory processing and brain volume alteration in conjunction with psychiatric symptom severity in patients with obsessive-compulsive disorder (OCD). METHODS:Twenty-OCD patients and 20-healthy control...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2020.0124
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:The purpose of the present study was to clarify the relationship between white matter tracts and cognitive symptoms in children with high-functioning autism spectrum disorder (ASD). METHODS:We examined the cognitive functions of 17 children with high-functioning ASD and 18 typically developing (TD) controls ...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.01.16
更新日期:2019-03-01 00:00:00
abstract:OBJECTIVE:Autistic spectrum traits are postulated to lie on a continuum that extends between individuals with autism and individuals with typical development. The present study was carried out to investigate functional and network abnormalities associated with autistic spectrum trait in healthy male subjects. METHODS:...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2018.07.27
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:Suicide is a leading cause of death in college age students. Identification of the associated risk factors has important implications for how to prevent and respond to this population; however, few studies have been performed on this topic in this age group. The purpose of this study was to evaluate the preva...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2008.5.2.86
更新日期:2008-06-01 00:00:00
abstract:OBJECTIVE:Previous studies have shown that there is a correlation between lipid levels and depressive mood, and that lipids could be useful biomarkers for depression. We conducted this study to clarify the association between lipid levels and depressive mood in adolescents, especially in community samples. METHODS:We ...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.30773/pi.2019.03.24
更新日期:2019-10-01 00:00:00
abstract:OBJECTIVE:To measure the prevalence of and factors associated with online inappropriate sexual exposure, cyber-bullying victimisation, and computer-using time in early adolescence. METHODS:A two-year, prospective school survey was performed with 1,173 children aged 13 at baseline. Data collected included demographic f...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2014.11.1.24
更新日期:2014-01-01 00:00:00
abstract::Sexual dysfunction is a common side effect in patients treated with antipsychotics but significant differences exist across different compounds. We report hypersexuality symptoms in two female patients with schizophrenia who were receiving treatment with aripiprazole. The patients experienced more frequent sexual desi...
journal_title:Psychiatry investigation
pub_type: 杂志文章
doi:10.4306/pi.2013.10.2.200
更新日期:2013-06-01 00:00:00