Abstract：
:Acute-onset, severe systolic hypertension; severe diastolic hypertension; or both can occur during the prenatal, intrapartum, or postpartum periods. Pregnant women or women in the postpartum period with acute-onset, severe systolic hypertension; severe diastolic hypertension; or both require urgent antihypertensive therapy. Introducing standardized, evidence-based clinical guidelines for the management of patients with preeclampsia and eclampsia has been demonstrated to reduce the incidence of adverse maternal outcomes. Individuals and institutions should have mechanisms in place to initiate the prompt administration of medication when a patient presents with a hypertensive emergency. Treatment with first-line agents should be expeditious and occur as soon as possible within 30-60 minutes of confirmed severe hypertension to reduce the risk of maternal stroke. Intravenous labetalol and hydralazine have long been considered first-line medications for the management of acute-onset, severe hypertension in pregnant women and women in the postpartum period. Although relatively less information currently exists for the use of calcium channel blockers for this clinical indication, the available evidence suggests that immediate release oral nifedipine also may be considered as a first-line therapy, particularly when intravenous access is not available. In the rare circumstance that intravenous bolus labetalol, hydralazine, or immediate release oral nifedipine fails to relieve acute-onset, severe hypertension and is given in successive appropriate doses, emergent consultation with an anesthesiologist, maternal-fetal medicine subspecialist, or critical care subspecialist to discuss second-line intervention is recommended.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Committee on Obstetric Practice.doi
10.1097/AOG.0000000000002019subject
Has Abstractpub_date
2017-04-01 00:00:00pages
e90-e95issue
4eissn
0029-7844issn
1873-233Xpii
00006250-201704000-00048journal_volume
129pub_type
杂志文章,实务指引abstract：OBJECTIVE:To assess the changes in the subpopulations of lymphocytes and in lymphocyte mitogenic activity in women with endometriosis receiving GnRH-agonist treatment. METHODS:Twenty-six women with advanced endometriosis from the National Cheng Kung University Medical College were studied. Each received a total of six...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章
doi：10.1016/s0029-7844(97)00145-2
更新日期：1997-06-01 00:00:00
abstract：:Variability of the baseline fetal heart rate is correlated with good fetal outcome, and loss of baseline variability has been observed as a sign of fetal distress. Central nervous system depressing drugs may also decrease fetal heart rate variability, and thus recognition of the effect of medication on the baseline fe...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1978-01-01 00:00:00
abstract：OBJECTIVE:To estimate whether first-trimester exposure to nitrofurantoin is associated with increased malformation rates and, secondarily, to estimate whether exposure to nitrofurantoin is associated with increased rates of negative pregnancy outcomes and perinatal complications. METHODS:We conducted a population-base...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e31827c5f88
更新日期：2013-02-01 00:00:00
abstract：:To study time trends in maternal mortality in the United States and to attempt to compare the risk of cesarean with vaginal delivery, information from the Professional Activities Study of the Commission on Professional and Hospital Activities for 3 years-1970, 1974, and 1978-was reviewed. For all deliveries, mortality...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1982-01-01 00:00:00
abstract：OBJECTIVE:To analyze cumulative conception rates and the prognostic factors influencing them during exogenous human menopausal gonadotropin (hMG) therapy for World Health Organization (WHO) group I or II ovulatory disorders. METHODS:A retrospective review was conducted of 468 treatment cycles in 146 women with ovulato...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1994-02-01 00:00:00
abstract：:A series of 117 patients with stage I squamous cell carcinoma of the vulva was followed for 3 to 21 years. Twenty recurrences (17.1%) were found, 12 in the vulva or vagina, 7 in the groin, and 1 in a patient who developed distant metastases. Invasion of tumor cells in lymph or blood vessels was found in operative spec...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1981-01-01 00:00:00
abstract：OBJECTIVE:To estimate an institution's specific fetal loss rate after a second-trimester genetic amniocentesis. METHODS:This is a retrospective cohort study using our prenatal diagnosis database for all pregnant women presenting for care between 1990 and 2006. We compared the fetal loss rate in women who underwent amn...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e318162eb53
更新日期：2008-03-01 00:00:00
abstract：OBJECTIVE:To evaluate the comparative safety of transcervical and transabdominal chorionic villus sampling (CVS). METHODS:From May 1988 to January 1992, CVS was performed by two operators at 9-12 weeks' gestation in 1048 singleton pregnancies. The sampling method for each patient, transabdominal or transcervical, was ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：OBJECTIVE:To address the impact of simple antenatal educational interventions on breastfeeding practice. METHODS:A randomized controlled trial was carried out in a tertiary referral center from May 2002 to December 2004. A random sample of eligible low-risk antenatal patients was recruited from clinics in the National...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,随机对照试验
doi：10.1097/01.AOG.0000249613.15466.26
更新日期：2007-01-01 00:00:00
abstract：OBJECTIVE:To compare lamellar body counts with the lecithin/sphingomyelin ratio and phosphatidylglycerol analysis in terms of assessment of risk of respiratory distress syndrome (RDS). METHODS:Lamellar body counts, lecithin-sphingomyelin ratios (L/Ss), and phosphatidylglycerol levels were assessed in 1611 amniotic flu...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,多中心研究
doi：10.1016/s0029-7844(00)01133-9
更新日期：2001-02-01 00:00:00
abstract：:Uncontrolled lipid peroxidation may play an important role in the pathophysiology of preeclampsia by causing vascular endothelial cell dysfunction. Sera contain antioxidant mechanisms that serve to control lipid peroxidation. We tested the hypothesis that the sera antioxidant protective mechanisms are diminished in wo...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：:To evaluate the effectiveness of a physician-based intervention to promote smoking cessation during pregnancy, we conducted this randomized controlled trial in the resident-staffed prenatal clinics at the University of North Carolina Women's Hospital . Two hundred fifty prenatal patients who smoked were enrolled at th...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0029-7844(95)00492-0
更新日期：1996-04-01 00:00:00
abstract：:This month we focus on current research in exercise in pregnancy. Dr. Blanchette discusses four recent publications, and each is concluded with a "bottom line" that is the take-home message. The complete reference for each can be found in on this page, along with direct links to the abstracts. ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000000658
更新日期：2015-02-01 00:00:00
abstract：:We report the first known case of Chediak-Higashi syndrome in human pregnancy. This rare autosomal recessive disorder is characterized by partial oculocutaneous albinism, decreased leukocyte chemotaxis, susceptibility to infection, and death in childhood. Pathognomonic giant cytoplasmic granules are postulated to be d...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：:Diurnal variations in plasma unconjugated and total estriol were assessed in 11 third-trimester subjects with uncomplicated pregnancies. Commercially available 125I-labeled radioimmunoassay kits were used. Total plasma estriols reach a nadir during the hours of sleep (400 and 700 hours) which exceeds the episodic fluc...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-05-01 00:00:00
abstract：:A patient undergoing evaluation for primary infertility with regular menses had a normal hysterosalpingogram in the follicular phase and underwent diagnostic laparoscopy the next day, with the finding of a tubal pregnancy. The patient had a negative serum pregnancy test. Although a normal hysterosalpingogram and negat...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-03-01 00:00:00
abstract：OBJECTIVE:To assess the morbidity associated with continuing the second-stage duration of labor, weighing the probability of spontaneous vaginal birth without morbidity compared with birth with serious maternal or neonatal complications. METHODS:In a retrospective cohort, we analyzed singleton, vertex births at 36 wee...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000002431
更新日期：2018-02-01 00:00:00
abstract：:This month, we focus on current research in preterm birth prevention. Dr. Andrews discusses recent publications, and each is concluded with a "bottom line" that is the take-home message. The complete reference for each can be found in on this page, along with direct links to the abstracts. ...
journal_title：Obstetrics and gynecology
pub_type： 评论,杂志文章
doi：10.1097/AOG.0b013e31829e41fc
更新日期：2013-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the effectiveness and safety of the vaginal application of misoprostol for induction of labor at term, with the interval duration from labor induction to vaginal birth as the primary outcome measure. METHODS:Two hundred twenty-two women with indications for induction of labor at term were randomi...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0029-7844(96)00220-7
更新日期：1996-10-01 00:00:00
abstract：:A healthy young woman with recurrent spontaneous abortion and septate uterus underwent hysteroscopic metroplasty with intracavitary instillation of 1350 mL of 10% dextran 40 in normal saline. After the operation, the patient developed acute hypervolemic pulmonary edema and severe coagulopathy due to temporary impairme...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-05-01 00:00:00
abstract：OBJECTIVES:To investigate the sensitivity of immunoblotting and enzyme-linked immunosorbent assay (ELISA) to detect autoantibodies to bullous pemphigoid antigen 180 in patients with pemphigoid gestationis and to correlate autoantibody serum levels with disease activity. METHODS:In serum samples obtained from 44 pregna...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/01.AOG.0000115506.76104.ad
更新日期：2004-04-01 00:00:00
abstract：:In order to evaluate changes in hemoglobin A1 levels during nondiabetic pregnancy, 19 pregnant women were followed by determination of hemoglobin A1 with a two to four week interval. There was an early decrease in the hemoglobin A1 level already between the 12th and 16th weeks of pregnancy, with a further decrease in ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1983-12-01 00:00:00
abstract：BACKGROUND:Heterotopic pregnancy is a rare event in natural conception cycles. Diagnosis of heterotopic pregnancy requires a high index of suspicion. Described herein is a reported case of a heterotopic pregnancy presenting as hematometra. CASE:A young, multiparous woman, with her last menstrual period 6 weeks before ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000142698.17433.cd
更新日期：2004-11-01 00:00:00
abstract：OBJECTIVE:To determine changes in length of incompetent cervices after cerclage, using transvaginal ultrasound. METHODS:Patients were enrolled in a prospective, observational study under an Institutional Review Board-approved protocol. McDonald or Shirodkar sutures were placed according to physician preference. Pre- a...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(98)00568-7
更新日期：1999-07-01 00:00:00
abstract：OBJECTIVE:To determine whether women with abnormal Papanicolaou smears who received educational brochures at the initial booking for colposcopy were more likely to complete recommended treatment and follow-up after 18-24 months than were those who did not receive the brochures. METHODS:One hundred eight women particip...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00006250-199404000-00016
更新日期：1994-04-01 00:00:00
abstract：OBJECTIVE:To compare the accuracy of predicted birth weight by the gestation-adjusted projection method using ultrasonographic measurements obtained just before and at term. METHODS:The study group comprised patients with singleton pregnancies who underwent sonograms between 34.0 and 36.9 weeks' gestation (period 1) a...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(99)00617-1
更新日期：2000-04-01 00:00:00
abstract：OBJECTIVE:To report our experience with essential thrombocythemia complicating pregnancy. METHODS:Over a 5-year period, we studied 21 women of reproductive age affected by essential thrombocythemia. Diagnoses were based on previously published Polycythemia Vera Study Group criteria. RESULTS:Five of our 21 patients be...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-199406000-00002
更新日期：1994-06-01 00:00:00
abstract：:In the 1970s, studies demonstrated that timely access to risk-appropriate neonatal and obstetric care could reduce perinatal mortality. Since the publication of the Toward Improving the Outcome of Pregnancy report, more than three decades ago, the conceptual framework of regionalization of care of the woman and the ne...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000460770.99574.9f
更新日期：2015-02-01 00:00:00
abstract：:Because autoimmune diseases are suspected of causing some cases of recurrent pregnancy loss, we sought clinical and serologic evidence of such diseases in a group of 277 women with recurrent pregnancy loss. Using HEp-2 cells as targets for an indirect immunofluorescence test for antinuclear antibodies, we compared the...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：OBJECTIVE:To assess whether the G allele of the serotonin receptor 1A C(-1019)G polymorphism is associated with premenstrual dysphoric disorder. METHODS:The study sample comprised 53 women with clinically diagnosed premenstrual dysphoric disorder (age range 27-46 years, mean 37.7 years) and 51 healthy control subjects...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000284448.73490.ac
更新日期：2007-10-01 00:00:00
