Consensus-Driven Development of a Terminology for Biobanking, the Duke Experience.

Abstract:

:Biobanking at Duke University has existed for decades and has grown over time in silos and based on specialized needs, as is true with most biomedical research centers. These silos developed informatics systems to support their own individual requirements, with no regard for semantic or syntactic interoperability. Duke undertook an initiative to implement an enterprise-wide biobanking information system to serve its many diverse biobanking entities. A significant part of this initiative was the development of a common terminology for use in the commercial software platform. Common terminology provides the foundation for interoperability across biobanks for data and information sharing. We engaged experts in research, informatics, and biobanking through a consensus-driven process to agree on 361 terms and their definitions that encompass the lifecycle of a biospecimen. Existing standards, common terms, and data elements from published articles provided a foundation on which to build the biobanking terminology; a broader set of stakeholders then provided additional input and feedback in a secondary vetting process. The resulting standardized biobanking terminology is now available for sharing with the biobanking community to serve as a foundation for other institutions who are considering a similar initiative.

journal_name

Biopreserv Biobank

authors

Ellis H,Joshi MB,Lynn AJ,Walden A

doi

10.1089/bio.2016.0092

subject

Has Abstract

pub_date

2017-04-01 00:00:00

pages

126-133

issue

2

eissn

1947-5535

issn

1947-5543

journal_volume

15

pub_type

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