Abstract：
INTRODUCTION:Because of the shortage of organs available for transplantation, living related sequential transplantation with the use of liver and a kidney from the same donor has emerged as a reasonable therapeutic alternative. However, there is insufficient literature about the complications that living donors experience after simultaneous kidney and liver transplantations. METHODS:From December 2001 to October 2009, 5 living donors provided simultaneous donation of livers and kidneys and 1 living donor donated first her kidney and then her liver. Demographic data of the donors and information concerning the surgery and postoperative observation were collected prospectively. RESULTS:All of the donors were female. The median age was 27.5 (range, 19-36) years. Indications requiring the simultaneous transplantation of livers and kidneys were primary hyperoxaluria type 1 (PH1) in 5 potential recipients and cirrhosis due to chronic hepatitis B infection and idiopathic chronic renal insufficiency in 1 potential recipient. Four recipients underwent right hepatectomy (segments 5-8) and right nephrectomy; 1 recipient underwent left hepatectomy (segments 2-4) and right nephrectomy; and 1 recipient underwent left lobectomy (segments 2-3) and right nephrectomy. There were no complications except in 1 donor (postoperative ileus). No donor developed hypertension or microalbuminuria. CONCLUSIONS:With the right indications, appropriate preoperative evaluation, meticulous surgical technique, proper postoperative care, and long-term close monitoring to minimize morbidity and mortality risks, liver and kidney donation from the same donor can be considered for simultaneous kidney and liver transplantation.
journal_name
Transplant Procjournal_title
Transplantation proceedingsauthors
Unek T,Egeli T,Özbilgin M,Çelik A,Atilla K,Ağalar C,Arslan NÇ,Karademir S,Bora S,Gülay H,Derici ZS,Astarcıoğlu Idoi
10.1016/j.transproceed.2017.01.020subject
Has Abstractpub_date
2017-04-01 00:00:00pages
403-406issue
3eissn
0041-1345issn
1873-2623pii
S0041-1345(17)30030-1journal_volume
49pub_type
杂志文章abstract：:Side effects of calcineurin inhibitors (CNIs) include nephrotoxicity and hypertension. Moreover, children have a higher risk of infections and posttransplantation lymphoproliferative disorders. We retrospectively evaluated the efficacy and safety of Sirolimus (SRL) in 18 patients, who were 10.52 +/- 5.03 years at time...
journal_title：Transplantation proceedings
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journal_title：Transplantation proceedings
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journal_title：Transplantation proceedings
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pub_type： 杂志文章
doi：10.1016/j.transproceed.2003.08.017
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journal_title：Transplantation proceedings
pub_type： 杂志文章
doi：10.1016/j.transproceed.2010.08.015
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pub_type： 杂志文章
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journal_title：Transplantation proceedings
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journal_title：Transplantation proceedings
pub_type： 杂志文章
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pub_type： 杂志文章
doi：10.1016/j.transproceed.2003.10.003
更新日期：2003-12-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.transproceed.2010.05.084
更新日期：2010-07-01 00:00:00
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journal_title：Transplantation proceedings
pub_type： 杂志文章,评审
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更新日期：2007-06-01 00:00:00
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更新日期：2016-11-01 00:00:00
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pub_type： 杂志文章
doi：10.1016/j.transproceed.2018.02.002
更新日期：2018-04-01 00:00:00
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doi：10.1016/j.transproceed.2013.07.014
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pub_type： 临床试验,杂志文章
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更新日期：2005-06-01 00:00:00
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pub_type： 杂志文章
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更新日期：2012-01-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章,多中心研究
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更新日期：2009-07-01 00:00:00
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更新日期：2020-12-01 00:00:00
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pub_type： 杂志文章
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更新日期：1992-10-01 00:00:00
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pub_type： 杂志文章
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更新日期：2008-09-01 00:00:00
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