Abstract：
:Intervention planning is essential for successful Mitral Valve (MV) repair procedures. Finite-element models (FEM) of the MV could be used to achieve this goal, but the translation to the clinical domain is challenging. Many input parameters for the FEM models, such as tissue properties, are not known. In addition, only simplified MV geometry models can be extracted from non-invasive modalities such as echocardiography imaging, lacking major anatomical details such as the complex chordae topology. A traditional approach for FEM computation is to use a simplified model (also known as parachute model) of the chordae topology, which connects the papillary muscle tips to the free-edges and select basal points. Building on the existing parachute model a new and comprehensive MV model was developed that utilizes a novel chordae representation capable of approximating regional connectivity. In addition, a fully automated personalization approach was developed for the chordae rest length, removing the need for tedious manual parameter selection. Based on the MV model extracted during mid-diastole (open MV) the MV geometric configuration at peak systole (closed MV) was computed according to the FEM model. In this work the focus was placed on validating MV closure computation. The method is evaluated on ten in vitro ovine cases, where in addition to echocardiography imaging, high-resolution μCT imaging is available for accurate validation.
journal_name
Med Image Analjournal_title
Medical image analysisauthors
Grbic S,Easley TF,Mansi T,Bloodworth CH,Pierce EL,Voigt I,Neumann D,Krebs J,Yuh DD,Jensen MO,Comaniciu D,Yoganathan APdoi
10.1016/j.media.2016.03.011subject
Has Abstractpub_date
2017-01-01 00:00:00pages
238-249eissn
1361-8415issn
1361-8423pii
S1361-8415(16)30018-4journal_volume
35pub_type
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