Abstract：
:Therapeutic hypothermia (TH) is a recommended regimen for newborn infants who are at or near term with evolving moderate-to-severe hypoxic ischemic encephalopathy (HIE). The Task Force of the Taiwan Child Neurology Society and the Taiwan Society of Neonatology held a joint meeting in 2015 to establish recommendations for using TH on newborn patients with HIE. Based on current evidence and experts' experiences, this review article summarizes the key points and recommendations regarding TH for newborns with HIE, including: (1) selection criteria for TH; (2) choices of method and equipment for TH; (3) TH prior to and during transport; (4) methods for temperature maintenance, monitoring, and rewarming; (5) systemic care of patients during TH, including the care of respiratory and cardiovascular systems, management of fluids, electrolytes, and nutrition, as well as sedation and drug metabolism; (6) monitoring and management of seizures; (7) neuroimaging, prognostic factors, and outcomes; and (8) adjuvant therapy for TH.
journal_name
Pediatr Neonatoljournal_title
Pediatrics and neonatologyauthors
Chiang MC,Jong YJ,Lin CHdoi
10.1016/j.pedneo.2016.11.001subject
Has Abstractpub_date
2017-12-01 00:00:00pages
475-483issue
6eissn
1875-9572issn
2212-1692pii
S1875-9572(17)30175-4journal_volume
58pub_type
杂志文章,评审abstract：BACKGROUND:The diagnosis of neonatal sepsis still considered to be a challenge for both clinicians and the laboratory due to the non-specific clinical presentations. The present study aimed to compare and assess the diagnostic & prognostic values of C-reactive protein (CRP), high sensitivity CRP (hsCRP), presepsin, int...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2018.05.001
更新日期：2019-04-01 00:00:00
abstract：BACKGROUND:Zellweger syndrome (ZS) is a peroxisome biogenesis disorder attributed to a mutation of the PEX genes family. The incidence of this disease in Africa and the Arab world remains unknown. This contribution is aimed at describing the clinical phenotype and biochemical features in Tunisian patients with ZS in or...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2016.08.011
更新日期：2017-12-01 00:00:00
abstract：BACKGROUND:Rankings of infant mortality rates are commonly cited international comparisons to assess the health status of individual countries. We compared the infant mortality rate of Taiwan with those of European countries for 2004 according to two definitions. METHODS:First, the countries were ranked on the basis o...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2015.07.006
更新日期：2016-08-01 00:00:00
abstract：:Recently, heated humidified high-flow nasal cannula (HHHFNC) has been introduced and applied as a noninvasive respiratory support in neonates. Although HHHFNC is widely used in neonates presenting with respiratory distress, the efficiency and safety when compared with nasal continuous positive airway pressure or nonin...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章,评审
doi：10.1016/j.pedneo.2016.08.007
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:Neonatal sepsis contributes to great mortality and morbidity among very-low-birth-weight (VLBW) infants. Prevalence and pathogen distribution of sepsis in the neonatal intensive care units (NICUs) vary with time and geographic location. Such information serves as a guide for selection of empirical antibiotic...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2012.06.003
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:Tracheostomy is a valuable procedure in infants and neonates with chronic respiratory failure or severe airway obstruction. The aim of this study is to identify the indication, hospital course, and long-term outcome in a cohort of infants who required tracheostomy in a neonatal and pediatric tertiary care ce...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2017.07.003
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Anterior displacement of the anus has been reported to be a cause of chronic constipation amongst young children. However, the normal position of the anus has not been studied in Taiwan. PATIENTS AND METHODS:Normal anal positioning was studied in 200 neonates (100 males and 100 females). All of these indivi...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/S1875-9572(09)60055-3
更新日期：2009-08-01 00:00:00
abstract：AIM:We aimed to define the etiologic and prognostic factors in live-born infants with hydrops fetalis (HF) in our tertiary neonatal intensive care unit over a 10-year period. METHODS:Medical records of newborn infants with HF during 2002-2011 were reviewed retrospectively. Demographic data, prenatal interventions, cli...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2013.07.008
更新日期：2014-04-01 00:00:00
abstract：:Head trauma is one of the most challenging fields of traumatology and demands immediate attention and intervention by first-line clinicians. Symptoms can vary from victim to victim and according to the victim's age, leading to difficulties in making timely and accurate decisions at the point of care. In children, fall...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章,评审
doi：10.1016/j.pedneo.2012.12.011
更新日期：2013-04-01 00:00:00
abstract：BACKGROUND:We conducted this study in order to evaluate whether laparoscopic appendectomy was an alternative therapeutic tool to open appendectomy for all stages of pediatric appendicitis. MATERIALS AND METHODS:Between January 2000 and November 2004, the charts of 177 children who underwent appendectomy by a single su...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2012.07.002
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND:Currently, the pediatrician shortage in Taiwan has raised concerns about pediatricians' workloads and wellbeing. This study aimed to understand in-hospital pediatricians' perceptions toward career satisfaction and their wellbeing. METHODS:A questionnaire exploring pediatricians' life management, commitment ...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2012.11.015
更新日期：2013-06-01 00:00:00
abstract：BACKGROUND:Despite advances in therapeutic modalities, congenital diaphragmatic hernia (CDH) still accounts for significant neonatal mortality. This study aimed to describe the demographic features, clinical experiences of postnatal care, and differences between non-survivors and survivors with CDH. METHODS:We retrosp...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/S1875-9572(10)60018-6
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:Human Rhinovirus (HRV) has been identified as the most common cause of acute respiratory infections and hospitalizations in premature children. It is unclear if premature children are more susceptible to HRV due to their decreased pulmonary reserve or because they have enhanced lower airway reactivity to HRV...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2017.04.008
更新日期：2018-06-01 00:00:00
abstract：:Nystagmus is an involuntary rhythmic oscillation of the eyes, which leads to reduced visual acuity due to the excessive motion of images on the retina. Nystagmus can be grouped into infantile nystagmus (IN), which usually appears in the first 3-6 months of life, and acquired nystagmus (AN), which appears later. IN can...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章,评审
doi：10.1016/j.pedneo.2014.02.007
更新日期：2014-10-01 00:00:00
abstract：:An otherwise healthy female baby who had received early postnatal antibiotic prophylaxis because of maternal vaginal group B streptococcal (GBS) colonization died of late-onset GBS meningitis. GBS was isolated from blood and cerebrospinal fluid. Genotyping using pulsed-field gel electrophoresis confirmed that the GBS ...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/S1875-9572(10)60046-0
更新日期：2010-08-01 00:00:00
abstract：BACKGROUND:To investigate the clinical values of serum melatonin and αII spectrin cleavage products (SBDPs) in assessing the severity of brain injury in preterm infants. METHODS:Sixty-four premature infants in total were selected and classified into the brain injury group (BI, n = 30) and the non-brain injury group (C...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2018.11.005
更新日期：2019-08-01 00:00:00
abstract：BACKGROUND:Esophageal atresia (EA) with or without tracheoesophageal fistula (TEF) remains one of the most common gastrointestinal neonatal malformations. Even though postoperative management is standardized, it differs between hospitals and disease-associated clinical factors that may play a role in outcome have not y...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2020.09.001
更新日期：2021-01-01 00:00:00
abstract：BACKGROUND:The parameters of oxidative stress [advanced oxidation protein products (AOPPs), malondialdehyde (MDA), and S100B] and the effect of intensive phototherapy (PT) on these parameters have not been studied extensively in newborns with significant hyperbilirubinemia (SH). We aimed to measure the levels of MDA, S...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2014.06.006
更新日期：2015-04-01 00:00:00
abstract：:Cerebro-costo-mandibular syndrome (CCMS) consists of severe micrognathia, glossoptosis, posterior rib-gap defects and developmental delay. It may cause upper airway obstruction andflail chest, resulting in neonatal hypoxia, and possibly death. Early airway management or surgical intervention to maintain a patent airwa...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/S1875-9572(10)60011-3
更新日期：2010-02-01 00:00:00
abstract：BACKGROUND:This study evaluated the feasibility and accuracy of the height-corrected definition for identifying metabolic syndrome (MS). METHODS:In 2006, anthropometric and biochemical measurements were assessed in a cross-sectional population-based study of 3136 Han adolescents, aged 13-17 years. MS was defined accor...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2016.03.008
更新日期：2017-04-01 00:00:00
abstract：:Respiratory distress syndrome (RDS) was recognized to be caused by primary surfactant deficiency almost 70 years ago and continuous positive airway pressure was introduced approximately 50 years ago. Since then, there have been many developments in neonatology; we know many things but others are still controversial. T...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2020.11.005
更新日期：2020-12-05 00:00:00
abstract：BACKGROUND:We aimed to study the changes of serum N-terminal pro-brain natriuretic to peptide (NT-proBNP) levels after asphyxia-induced myocardial injury in children and explore the relationship between serum NT-proBNP levels and neonatal asphyxia. METHODS:One hundred and six cases of neonatal asphyxia were randomly s...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2015.08.001
更新日期：2016-04-01 00:00:00
abstract：BACKGROUND:Most small muscular ventricular septal defect (M-VSD) types have been diagnosed using color Doppler echocardiography. The purpose of this study was to understand the incidence of small M-VSD in the neonatal period and analyze the natural history of these M-VSDs. MATERIALS AND METHODS:All individuals in our ...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2011.06.003
更新日期：2011-10-01 00:00:00
abstract：:Multicystic dysplastic kidney (MCDK) is a congenital maldevelopment in which the renal cortex is characteristically replaced by numerous cysts of multiple sizes. MCDK presenting as a single predominant large cyst in morphology is less common. We report on the prenatal imaging findings and perinatal management of a fet...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2011.05.009
更新日期：2011-08-01 00:00:00
abstract：BACKGROUND:The gastroesophageal reflux disease (GERD) questionnaire (GerdQ) is a validated questionnaire that was developed recently to help identify GERD patients. The sensitivity and specificity of GerdQ for the diagnosis of GERD in adult patients were 65% and 71%, respectively. Because the application of GerdQ in pe...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2014.01.004
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:A yearly increase in the proportion of very low birth weight (VLBW) live births has resulted in the slowdown of decreasing trends in crude infant mortality rates (IMRs). In this study, we examined the trends in birth weight-specific as well as birth weight-adjusted IMRs in Taiwan. METHODS:We linked three na...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2017.08.013
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:Screening for infectious diseases in newborns using immunoglobulin (Ig)A-, IgM-, and IgE-specific antibodies is expensive and impractical. To determine if total levels of these Igs can be used for screening purposes, thus simplifying the process, their basic levels in the 1(st) month of extrauterine life nee...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2015.06.005
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:Domperidone has been widely used in children with gastroesophageal reflux disease (GERD). Studies on the effects of domperidone on corrected QT interval (QTc) in young children are limited. Our aim was to study the effect of domperidone on the repolarization abnormalities assessed by electrocardiogram (ECG) ...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2015.03.015
更新日期：2016-02-01 00:00:00
abstract：BACKGROUND:Community-acquired Gram-Negative (GN) bacteremia caused more morbidity and mortality recently in children. The increasing drug resistance was also an important issue. However, published reference was few about children. METHODS:We conducted a retrospective study to collect febrile patients with blood cultur...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2019.05.009
更新日期：2020-02-01 00:00:00
abstract：BACKGROUND:Circulatory collapse is a very common complication of the critical illnesses in neonates including neonates with hypoxic ischemic encephalopathy; it can be the end result and cause of death of several conditions. Often, despite treatment with fluid resuscitation and vasopressor agents, circulatory collapse p...
journal_title：Pediatrics and neonatology
pub_type： 杂志文章
doi：10.1016/j.pedneo.2016.09.010
更新日期：2017-12-01 00:00:00
