Potential of morin and hesperidin in the prevention of cisplatin-induced nephrotoxicity.

abstract：BACKGROUND:An elevated serum C-reactive protein (CRP) is strongly associated with morbidity and mortality in dialysis patients. However, the significance of high CRP levels in pre-dialysis patients has not been studied extensively. The aim of this study was to determine the prevalence of elevated serum CRP in pre-dialy...

journal_title：Renal failure

authors： Razeghi E,Parkhideh S,Ahmadi F,Khashayar P

更新日期：2008-01-01 00:00:00

abstract：:In kidney disease, inflammation and lipid dysmetabolism are often associated together, however, the effect and mechanism of inflammatory mediators and lipid dysmetabolism on kidney damage is still unclear. In this study, Wistar rats were randomized into four groups: normal diet + saline (Group N), high-fat diet (HF)+ ...

journal_title：Renal failure

authors： Wang Z,Huang W,Li H,Tang L,Sun H,Liu Q,Zhang L

更新日期：2018-11-01 00:00:00

abstract：:Transforming growth factor-β1 (TGF-β1) is a crucial factor implicated in the development of renal inflammation and tubulointerstitial fibrosis (TIF). The cytokine interleukin 22 (IL-22) was previously reported to involve in the pathogenesis of chronic inflammatory diseases, however recent studies showed that IL-22 cou...

journal_title：Renal failure

authors： Tang R,Xiao X,Lu Y,Li H,Zhou Q,Kwadwo Nuro-Gyina P,Li X

更新日期：2020-11-01 00:00:00

abstract：:The study of urinary proteins is an important tool in the screening and diagnosis of patients with renal impairment. Quantification of total proteins, although useful, can provide only limited information. Gel electrophoresis of urine samples may provide more detailed information. ...

journal_title：Renal failure

authors： Behets GJ,De Broe ME

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Determination of fluid overload is important in chronic kidney disease. Early diagnosis and treatment of volume overload may decrease morbidity and mortality. We aimed to determine body composition by using bioelectrical impedance analysis, and studying other clinical characteristics, inferior vena cava diam...

journal_title：Renal failure

authors： Yilmaz Z,Yildirim Y,Oto F,Aydin FY,Aydin E,Kadiroglu AK,Yilmaz ME

更新日期：2014-05-01 00:00:00

abstract：:Electrolyte disorders can alter cardiac ionic currents and depending on the changes can promote proarrhythmic effects. Potassium (K(+)) is the most common intracellular cation related to arrhythmic disorders. Hyperkalemia is mainly seen in the setting of impaired renal function. Severe hyperkalemia may lead to rhythm ...

journal_title：Renal failure

authors： Gul EE,Erdogan HI,Yıldırım O,Soylu A,Nikus KC

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:A unique form of postinfectious glomerulonephritis (PIGN) with IgA-dominant deposition mimicking IgA nephropathy has been increasingly reported. METHODS:We compared the clinical and histological features of 12 patients with postinfectious IgA-dominant glomerulonephritis to 134 patients with idiopathic IgA n...

journal_title：Renal failure

authors： Wen YK,Chen ML

更新日期：2010-06-01 00:00:00

abstract：:Microalbumin is a basic biochemical test that is widely used at present. Owing to the concept of point-of-care testing (POCT), there are tools available for analysis of microalbumin. Here, the author performs a brief assessment on weight-turnaround time properties for available POCT for determination of microalbumin i...

journal_title：Renal failure

authors： Wiwanitkit V

更新日期：2010-05-01 00:00:00

abstract：OBJECTIVES:To evaluate how chronic kidney disease (CKD) and diabetes mellitus (DM) influence in-hospital mortality in patients urgently admitted for acute heart failure (HF). METHODS:We used data from the Spanish "Minimum Basic Data Set" for 2006-2007 to evaluate clinical differences and crude mortality rates for pati...

journal_title：Renal failure

authors： de Miguel-Yanes JM,Méndez-Bailón M,Marco-Martínez J,Zapatero-Gaviria A,Barba-Martín R

更新日期：2014-11-01 00:00:00

abstract：:Objectives: To improve the mouse model of relief for unilateral ureteral obstruction (RUUO) and explore the pathological process of renal fibrosis after the obstruction was relieved. Methods: C57BL/6 mice in model group were randomly divided into RUUO group, improved RUUO group, and UUO group. After leaving Unilateral...

journal_title：Renal failure

authors： Song J,Liu J,Luo J,Zhang Q,Xia Y,Shao Q,Sun C,Jiang C,Zhang M,Zhu W

更新日期：2019-11-01 00:00:00

abstract：:Granulomatous interstitial nephritis (GIN) is a rare disease. Contributing factors such as drugs, sarcoidosis, infections, and paraproteinemia have been reported, and when no obvious contributing factors can be identified, the disease is classified as idiopathic GIN. We managed a patient with idiopathic GIN with an un...

journal_title：Renal failure

authors： Kim SJ,Hee Sung S

更新日期：2010-01-01 00:00:00

abstract：:Creatol (CTL) is a hydroxyl radical adduct of creatinine (Cr). The serum methylguanidine (MG) level and the MG/Cr molar ratio are reported to be biomarkers for oxidative stress. The aim of this study was to examine whether urinary excretion of CTL, another oxidative stress-related marker, is increased in patients with...

journal_title：Renal failure

authors： Ienaga K,Nakamura K,Fujisawa T,Fukunaga Y,Nihei H,Narita M,Tomino Y,Sanaka T,Aoyagi K,Nakano K,Koide H

更新日期：2007-01-01 00:00:00

abstract：:Psoriasis, being limited to the skin, is generally a chronic inflammatory disorder. Several glomerular diseases have been distinguished due to renal histological findings of psoriatic patients to date. The underlying pathogenetic mechanisms of these associations remain unclear because of the limited number of cases. W...

journal_title：Renal failure

authors： Ceri M,Kurultak I,Unverdi S,Altay M,Duranay M

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Despite the widespread availability of dialytic and intensive care unit technology, the probability of early mortality in critically ill patients with acute renal failure (ARF) is still high, and the evaluation of the patients' prognosis has been difficult. The Acute Physiology and Chronic Health Evaluation ...

journal_title：Renal failure

authors： Chen YC,Hsu HH,Kao KC,Fang JT,Huang CC

更新日期：2001-01-01 00:00:00

abstract：:N-acetylglucosaminidase (NAG) is a lysosomal enzyme produced by renal proximal tubular cells and has been widely used as a marker, which indicates a degree of renal tubular damage. An increase in urinary NAG excretion is though to result from the renal tubular damage. The aim of this study was to evaluate whether even...

journal_title：Renal failure

authors： Fujita H,Narita T,Morii T,Shimotomai T,Yoshioka N,Kakei M,Ito S

更新日期：2002-01-01 00:00:00

abstract：:Pentoxifylline (PTX) has been reported to inhibit TNF-alpha production and prevent several types of acute renal failure. This study was undertaken to determine the effect of PTX on the cisplatin-induced acute renal failure in rabbits. Rabbits received a single injection of cisplatin (5 mg/kg, i.p.) with or without PTX...

journal_title：Renal failure

authors： Kim YK,Choi TR,Kwon CH,Kim JH,Woo JS,Jung JS

更新日期：2003-11-01 00:00:00

abstract：:Patients with end-stage renal disease, including those treated with peritoneal dialysis, have a high risk for death, particularly from cardiovascular causes. Plasma fatty acid (FA) composition is used as an indicator of disease risk, because its alteration has been related to metabolic disease and cardiovascular disea...

journal_title：Renal failure

authors： Yerlikaya FH,Mehmetoglu I,Kurban S,Tonbul Z

更新日期：2011-01-01 00:00:00

abstract：:Despite advanced techniques of renal replacement therapy the overall mortality of patients with ARF is still high. The majority of patients with ARF requiring dialysis are those with nontraumatic ARF. In a retrospective study we compared the causes of nontraumatic ARF, the risk factors for the development of renal fai...

journal_title：Renal failure

authors： Schmekal B,Pichler R,Biesenbach G

更新日期：2004-01-01 00:00:00

abstract：:During embryonic life, renal morphogenesis is characterized by a defined period of intense cellular activity, inductive-transformation of undifferentiated cells to polarized epithelia, in-growth of capillaries into an intricate parenchymal epithelial-mesenchymal mass, and finally the maturation into an organ with dive...

journal_title：Renal failure

authors： Wallner EI,Kumar A,Carone FA,Kanwar YS

更新日期：1998-03-01 00:00:00

abstract：:Our study is a prospective one conducted at Al-Amiri Hospital and including all new cases of chronic renal disease (CRD) seen at the capital area of Kuwait between 1 January 1999 and 30 December 2003. Diagnosis of CRD was based on clinical, laboratory, and radiological features. Kidney biopsies were done when indicate...

journal_title：Renal failure

authors： El-Reshaid W,El-Reshaid K,Kapoor M,Hakim A

更新日期：2005-01-01 00:00:00

abstract：UNLABELLED:Cardiovascular diseases are the major cause of morbidity and mortality in renal transplant recipients. We report our experience in the treatment of patients with renal allograft who required cardiovascular surgery. METHODS:Indications for cardiovascular surgery, postoperative complications, and outcome were...

journal_title：Renal failure

authors： Basic-Jukic N,Ivanac-Jankovic R,Biocina B,Kes P

更新日期：2015-07-01 00:00:00

abstract：:Diabetic nephropathy (DN) has become the most common pathogenesis of end-stage renal disease. Plasminogen activator inhibitor-1 (PAI-1) plays an important role in the pathogenesis of DN. A meta-analysis was conducted to investigate the association between 4 G/5 G variants in the PAI-1 gene and DN susceptibility. Datab...

journal_title：Renal failure

authors： Xue C,Nie W,Zhou C,Yu F,Wang DM,Dai B,Mei CL

更新日期：2014-04-01 00:00:00

abstract：:Prophylactic effects of N-benzoyl-beta-alanine (betamipron, BP), one of a series of N-acyl amino acids, were examined against cisplatin-induced nephrotoxicity. Male Wistar rats were injected i.p. with 6 mg/kg of cisplatin combined with an i.p. BP dose given at various times and various doses. Rats were sacrificed 5 da...

journal_title：Renal failure

authors： Tokunaga J,Kobayashi M,Nakamura C,Kitagawa A,Arimori K,Nakano M

更新日期：1996-03-01 00:00:00

abstract：:Chromogranin A (CGA) is a low MW (49,000) acidic hydrophilic protein. It is synthesized in the chromaffm granules of the neuroendocrine cells, and has been found circulating in the blood of healthy subjects. The aim of this study was to assess the relationship between serum levels of CGA and renal function. One hundre...

journal_title：Renal failure

authors： Tramonti G,Ferdeghini M,Annichiarico C,Norpoth M,Donadio C,Bianchi R,Bianchi C

更新日期：2001-05-01 00:00:00

abstract：:Abstract TGF-β1 plays an important role in the pathogenesis of chronic renal diseases. Although the specific mechanism is unknown, a major factor is the potent fibrogenic activity of TGF-β1 in the chronic progression of renal diseases. TGF-β1 closely correlates with renal fibrosis in cooperation with several fibrosis-...

journal_title：Renal failure

authors： Qi R,Li W,Yu S

更新日期：2014-05-01 00:00:00

abstract：AIM:The aim of the present study was to investigate the value of the urine cell glycoprotein 1 (PC-1), aminopeptidase N (APN), N-acetyl-beta-D-glucosaminidase (NAGA), and dipeptidylpeptidase IV (DPP IV) in the evaluation of tubular damage in patients with primary glomerulonephritis, diabetic nephropathy, and lupus neph...

journal_title：Renal failure

authors： Mitic B,Lazarevic G,Vlahovic P,Rajic M,Stefanovic V

更新日期：2008-01-01 00:00:00

abstract：:This article describes several topics necessary for understanding the psychological impact of disasters. Topics discussed include characteristics of disaster that impact psychological response, stages of response, factors influencing individual and collective trauma, and important aspects of psychological intervention...

journal_title：Renal failure

authors： Flynn BW

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Peritonitis, the most important limitation of peritoneal dialysis (PD), could be detected by biomarkers in dialysate effluent, representing a noninvasive method to indirectly assess the peritoneum status. The aim of our study was to test high mobility group box 1 (HMGB1) in PD patients, evaluating its role a...

journal_title：Renal failure

authors： Chimenz R,Lacquaniti A,Colavita L,Chirico V,Fede C,Buemi M,Fede C

更新日期：2016-10-01 00:00:00

abstract：:More than 70% of acute renal failure in man is of circulatory nature and results from hypoxic injury to the kidney. Since intrarenal hemodynamic and metabolic events cannot be accurately assessed in human acute renal failure, various experimental models of renal hypoperfusion or complete interruption of renal blood su...

journal_title：Renal failure

authors： Mohaupt M,Kramer HJ

更新日期：1989-01-01 00:00:00

abstract：:The influence of L-carnitine supplementation on hematocrit (Hct) and hemoglobin (Hb) levels, in patients suffering from end stage renal disease (ESRD) on maintenance hemodialysis, are well known from several studies. The data concerning the serum levels of carnitine, in patients with ESRD on continuous ambulatory peri...

journal_title：Renal failure

authors： Sotirakopoulos N,Athanasiou G,Tsitsios T,Mavromatidis K

更新日期：2002-07-01 00:00:00