Antibiotic prophylaxis in cataract surgery in the setting of penicillin allergy: A decision-making algorithm.

Abstract:

:Cataract surgery is the most commonly performed surgical procedure in many developed countries. Postoperative endophthalmitis is a rare complication with potentially devastating visual outcomes. Currently, there is no global consensus regarding antibiotic prophylaxis in cataract surgery despite growing evidence of the benefits of prophylactic intracameral cefuroxime at the conclusion of surgery. The decision about which antibiotic regimen to use is further complicated in patients reporting penicillin allergy. Historic statistics suggesting crossreactivity of penicillins and cephalosporins have persisted into modern surgery. It is important for ophthalmologists to consider all available antibiotic options and have an up-to-date knowledge of antibiotic crossreactivity when faced with the dilemma of choosing appropriate antibiotic prophylaxis for patients undergoing cataract surgery with a history of penicillin allergy. Each option carries risks, and the choice may have medicolegal implications in the event of an adverse outcome. We assess the options for antibiotic prophylaxis in cataract surgery in the setting of penicillin allergy and provide an algorithm to assist decision-making for individual patients.

journal_name

Surv Ophthalmol

journal_title

Survey of ophthalmology

authors

LaHood BR,Andrew NH,Goggin M

doi

10.1016/j.survophthal.2017.04.004

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

659-669

issue

5

eissn

0039-6257

issn

1879-3304

pii

S0039-6257(16)30273-9

journal_volume

62

pub_type

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