Abstract:
:Propionibacterium acnes is a key pathogenic factor in the development of acne. Antibiotics are the first choice of treatment for mild-to-moderate, mixed, papular/pustular, and moderate nodular acne, and an alternative choice in severe, nodular/conglobate acne. The emergence of resistance to the currently available antibiotics poses a serious set-back to this algorithm, and the reduced arsenal can diminish efficacy of treatment. This emerging situation should catalyze innovations in dermatology; for example, newer drugs and technologies such as next-generation antibiotics with excellent potency and low propensity to develop resistance, rapid diagnostic platforms to select responders and nonresponders, and delivery technologies that target the bacteria. Such innovations can dramatically expand the arsenal for dermatologists in the management of acne.
journal_name
Semin Cutan Med Surgjournal_title
Seminars in cutaneous medicine and surgeryauthors
Sinha M,Sadhasivam S,Bhattacharyya A,Jain S,Ghosh S,Arndt KA,Dover JS,Sengupta Sdoi
10.12788/j.sder.2016.031subject
Has Abstractpub_date
2016-06-01 00:00:00pages
62-7issue
2eissn
1085-5629issn
1558-0768journal_volume
35pub_type
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