Transcribing the connectome: roles for transcription factors and chromatin regulators in activity-dependent synapse development.

abstract：:1. The caudal photoreceptor (CPR) interneurons in the sixth abdominal ganglion of the crayfish are complex, multi-modal interneurons. These cells respond directly to light with tonic spike discharges, and they integrate synaptic input from an array of fili-form mechanoreceptors on the tailfan. They also provide input ...

journal_title：Journal of neurophysiology

authors： Pei X,Wilkens LA,Moss F

更新日期：1996-11-01 00:00:00

abstract：:Current-clamp recordings were made from the deep cerebellar nuclei (DCN) of 12- to 15-day-old rats to understand the factors that mediate intrinsic spontaneous firing patterns. All of the cells recorded were spontaneously active with spiking patterns ranging continuously from regular spiking to spontaneous bursting wi...

journal_title：Journal of neurophysiology

authors： Aizenman CD,Linden DJ

更新日期：1999-10-01 00:00:00

abstract：:The ventral pallidum (VP) is a key structure in brain mesocorticolimbic reward circuits that mediate "liking" reactions to sensory pleasures. Do firing patterns in VP actually code sensory pleasure? Strong evidence for hedonic coding requires showing that neural signals track positive increases in sensory pleasure or ...

journal_title：Journal of neurophysiology

authors： Tindell AJ,Smith KS,Peciña S,Berridge KC,Aldridge JW

更新日期：2006-11-01 00:00:00

abstract：:It is shown that the primate primary taste cortex represents not only taste but also information about many nontaste properties of oral stimuli. Of 1,122 macaque anterior insular/frontal opercular neurons recorded, 62 (5.5%) responded to oral stimuli. Of the orally responsive neurons, some (53%) represented the viscos...

journal_title：Journal of neurophysiology

authors： Verhagen JV,Kadohisa M,Rolls ET

更新日期：2004-09-01 00:00:00

abstract：:1. The inhibitory response of exogenously applied glycine was investigated in freshly dissociated rat nucleus tractus solitarii neurons under whole cell configuration using new perforated patch-clamp technique termed "gramicidin perforated patch technique," which maintains intact intracellular Cl- concentrations. 2. U...

journal_title：Journal of neurophysiology

authors： Rhee JS,Ebihara S,Akaike N

更新日期：1994-09-01 00:00:00

abstract：:The suppressive action of a moving textured background on responses to moving bars was investigated in 118 striate neurons, 19 dorsal lateral geniculate neurons, and 5 perigeniculate neurons in paralyzed and anesthetized cats. In standard conditions the background was a two-dimensional (2D) noise pattern, the bar move...

journal_title：Journal of neurophysiology

authors： Gulyás B,Orban GA,Duysens J,Maes H

更新日期：1987-06-01 00:00:00

abstract：:We asked whether podokinetic adaptation to walking on a circular treadmill transfers to different forms of locomotion. Subjects were blindfolded and asked to walk straight across the floor, in the forward and backward directions, following podokinetic (PK) stimulation that consisted of 30 min of forward walking-in-pla...

journal_title：Journal of neurophysiology

authors： Earhart GM,Jones GM,Horak FB,Block EW,Weber KD,Fletcher WA

更新日期：2001-10-01 00:00:00

abstract：:1. We study the propagation and dynamics of spindle waves in thalamic slices by developing and analyzing a model of reciprocally coupled populations of excitatory thalamocortical (TC) neurons and inhibitory thalamic reticular (RE) neurons. 2. Each TC neuron has three intrinsic ionic currents: a low-threshold T-type Ca...

journal_title：Journal of neurophysiology

authors： Golomb D,Wang XJ,Rinzel J

更新日期：1996-02-01 00:00:00

abstract：:The performance of neural codes to represent attributes of sensory signals has been evaluated in the vertebrate peripheral and central nervous system. Here, we determine how information signaled by populations of neurons is modified by plasticity. Suprathreshold neuronal responses from a large number of neurons were r...

journal_title：Journal of neurophysiology

authors： Pita-Almenar JD,Ranganathan GN,Koester HJ

更新日期：2011-09-01 00:00:00

abstract：:The high variability of cortical sensory responses is often assumed to impose a major constraint on efficient computation. In the auditory cortex, however, response variability can be very low. We have used in vivo whole cell patch-clamp methods to study the trial-to-trial variability of the subthreshold fluctuations ...

journal_title：Journal of neurophysiology

authors： Deweese MR,Zador AM

更新日期：2004-09-01 00:00:00

abstract：:Slow covariations in neuronal resting potentials can lead to artefactually fast cross-correlations in their spike trains. J. Neurophysiol. 80: 3345-3351, 1998. A model of two lateral geniculate nucleus (LGN) cells, which interact only through slow (tens of seconds) covariations in their resting membrane potentials, is...

journal_title：Journal of neurophysiology

authors： Brody CD

更新日期：1998-12-01 00:00:00

abstract：:Serotonergic fibers broadly innervate the thalamus and may influence the sleep wake cycle, attention, and other processes through modulation of neurons in this structure. However, the actions of serotonin in the dorsal thalamus have been investigated in detail only in the dorsal lateral geniculate nucleus. In the pres...

journal_title：Journal of neurophysiology

authors： Monckton JE,McCormick DA

更新日期：2002-04-01 00:00:00

abstract：:Results from previous studies suggest that two-dimensional spatial patterns are processed similarly in vision and touch when the patterns are equated for effective size or when visual stimuli are blurred to mimic the spatial filtering of the skin. In the present study, we measured subjects' ability to perceive the sha...

journal_title：Journal of neurophysiology

authors： Cho Y,Craig JC,Hsiao SS,Bensmaia SJ

更新日期：2016-01-01 00:00:00

abstract：:Synchronization between the firing times of simultaneously active motor units (MUs) is generally assumed to increase during fatiguing contractions. To date, however, estimates of MU synchronization have relied on indirect measures, derived from surface electromyographic (EMG) interference signals. This study used intr...

journal_title：Journal of neurophysiology

authors： McManus L,Hu X,Rymer WZ,Suresh NL,Lowery MM

更新日期：2016-06-01 00:00:00

abstract：:Electrical stimulation has been delivered to the basal ganglia (BG) to treat intractable symptoms of a variety of clinical disorders. However, it is still unknown how such treatments improve behavioral symptoms. A difficulty of this problem is that artificial signals created by electrical stimulation interact with int...

journal_title：Journal of neurophysiology

authors： Watanabe M,Munoz DP

更新日期：2013-07-01 00:00:00

abstract：:Divergence of the Shaker superfamily of voltage-gated (Kv) ion channels early in metazoan evolution created numerous electrical phenotypes that were presumably selected to produce a wide range of excitability characteristics in neurons, myocytes, and other cells. A comparative approach that emphasizes this early radia...

journal_title：Journal of neurophysiology

authors： Klassen TL,Buckingham SD,Atherton DM,Dacks JB,Gallin WJ,Spencer AN

更新日期：2006-05-01 00:00:00

abstract：:We investigated spike-frequency adaptation of neurons sensitive to interaural phase disparities (IPDs) in the inferior colliculus (IC) of urethane-anesthetized guinea pigs using a stimulus paradigm designed to exclude the influence of adaptation below the level of binaural integration. The IPD-step stimulus consists o...

journal_title：Journal of neurophysiology

authors： Ingham NJ,McAlpine D

更新日期：2004-02-01 00:00:00

abstract：:In the visual, auditory, and electrosensory modalities, stimuli are defined by first- and second-order attributes. The fast time-pressure signal of a sound, a first-order attribute, is important, for instance, in sound localization and pitch perception, while its slow amplitude-modulated envelope, a second-order attri...

journal_title：Journal of neurophysiology

authors： Fontaine B,MacLeod KM,Lubejko ST,Steinberg LJ,Köppl C,Peña JL

更新日期：2014-07-15 00:00:00

abstract：:1. Current- and voltage-clamp studies were conducted on isolated rat adrenal chromaffin cells to identify the voltage-dependent ion channels mediating inward currents. 2. Mean resting membrane potential of the isolated cells was -62 +/- 3 (SE) mV. Evoked action potentials were both Na+ and Ca2+ based, and whole cell v...

journal_title：Journal of neurophysiology

authors： Hollins B,Ikeda SR

更新日期：1996-08-01 00:00:00

abstract：:1. The effects of inhibitory amino acid transmitters on horizontal cells in the superfused amphibian retina were studied by the use of conventional intracellular recording techniques. 2. Gamma-aminobutyric acid (GABA) caused a calcium-independent depolarization of horizontal cells in mud puppy and tiger salamander. Th...

journal_title：Journal of neurophysiology

authors： Stockton RA,Slaughter MM

更新日期：1991-03-01 00:00:00

abstract：:The nucleus accumbens (NAcc) is a brain region involved in functions ranging from motivation and reward to feeding and drug addiction. The NAcc is typically divided into two major subdivisions, the shell and the core. The primary output neurons of both of these areas are medium spiny neurons (MSNs), which are quiescen...

journal_title：Journal of neurophysiology

authors： Brundege JM,Williams JT

更新日期：2002-07-01 00:00:00

abstract：:Under constant light-adapted conditions, vision seems to be rather linear. However, the processes underlying the synaptic transmission between cones and second-order neurons (bipolar cells and horizontal cells) are highly nonlinear. In this paper, the gain-characteristics of the transmission from cones to horizontal c...

journal_title：Journal of neurophysiology

authors： Kraaij DA,Spekreijse H,Kamermans M

更新日期：2000-09-01 00:00:00

abstract：:When a monkey attends to, remembers, and looks toward targets, the activity of some neurons in the lateral intraparietal area (LIP) changes. We recorded from isolated neurons during both a spatial and a shape match-to-sample task to examine and characterize voluntary active processes in LIP. Many LIP neurons show spat...

journal_title：Journal of neurophysiology

authors： Sereno AB,Amador SC

更新日期：2006-02-01 00:00:00

abstract：:Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) is widely used as a measure of neuronal activity, despite an incomplete understanding of the hemodynamic and neural bases for BOLD signals. Recent work by Lee and colleagues investigated whether activating genetically specified neuro...

journal_title：Journal of neurophysiology

authors： Palmer HS

更新日期：2010-10-01 00:00:00

abstract：:Humans with spinal cord injury (SCI) modulate locomotor output in response to limb load. Understanding the neural control mechanisms responsible for locomotor adaptation could provide a framework for selecting effective interventions. We quantified feedback and feedforward locomotor adaptations to limb load modulation...

journal_title：Journal of neurophysiology

authors： Gordon KE,Wu M,Kahn JH,Schmit BD

更新日期：2010-09-01 00:00:00

abstract：:Paired-pulse transcranial magnetic stimulation (TMS) can be used to examine intracortical inhibition in primary motor cortex (M1), termed short-interval intracortical inhibition (SICI). To our knowledge, SICI has only been demonstrated in contralateral motor evoked potentials (MEPs). Ipsilateral MEPs (iMEPs) are assum...

journal_title：Journal of neurophysiology

authors： McCambridge AB,Stinear JW,Byblow WD

更新日期：2016-03-01 00:00:00

abstract：:Changes in temperature of up to several degrees have been reported in different brain regions during various behaviors or in response to environmental stimuli. We investigated temperature sensitivity of dopaminergic neurons of the rat substantia nigra pars compacta (SNc), an area important for motor and emotional cont...

journal_title：Journal of neurophysiology

authors： Guatteo E,Chung KK,Bowala TK,Bernardi G,Mercuri NB,Lipski J

更新日期：2005-11-01 00:00:00

abstract：:Humans quickly and sophisticatedly correct their movements in response to changes in the world, such as when reaching to a target that abruptly changes its location. The vigor of these movement corrections is time-dependent, increasing if the time left to make the correction decreases, which can be explained by optima...

journal_title：Journal of neurophysiology

authors： Oostwoud Wijdenes L,van Beers RJ,Medendorp WP

更新日期：2019-09-01 00:00:00

abstract：:Discrete anatomic structures in the monkey somatic sensory thalamus may segregate input arising from different peripheral receptors and from different parts of the body. It has been proposed that these structures serve as components of modality- and place-specific pathways from the periphery to the cortex. We now test...

journal_title：Journal of neurophysiology

authors： Patel S,Ohara S,Dougherty PM,Gracely RH,Lenz FA

更新日期：2006-02-01 00:00:00

abstract：:Although species-specific differences in ion channel properties are well-documented, little has been known about the properties of the human Nav1.8 channel, an important contributor to pain signaling. Here we show, using techniques that include voltage clamp, current clamp, and dynamic clamp in dorsal root ganglion (D...

journal_title：Journal of neurophysiology

authors： Han C,Estacion M,Huang J,Vasylyev D,Zhao P,Dib-Hajj SD,Waxman SG

更新日期：2015-05-01 00:00:00