Abstract：
:Systems investigated with NMR spectroscopy are sometimes heterogeneous with respect to chemical composition, rates of chemical exchange, and other properties influencing magnetic resonance parameters. A method was developed to spatially encode reaction kinetic information and produce NMR images sensitive to chemical exchange. A modified spin-echo pulse sequence was used to allow chemical shift-selective imaging and chemical exchange encoding. 1H and 31P images with microscopic resolution were obtained which yielded chemical exchange as a function of position. Chemical exchange images of the base-catalyzed proton exchange of acetylacetone and of the enzyme-catalyzed 31P transfer between PCr and ATP were obtained at 8.4 T in phantoms at 360 and 146 MHz, respectively. These images demonstrate a means of investigating kinetic heterogeneity and compartmentalization of reactions that are important in the study of both living and non-living systems.
journal_name
Magn Reson Imagingjournal_title
Magnetic resonance imagingauthors
McFarland EW,Neuringer LJ,Kushmerick MJdoi
10.1016/0730-725x(88)90125-7subject
Has Abstractpub_date
1988-09-01 00:00:00pages
507-15issue
5eissn
0730-725Xissn
1873-5894pii
0730-725X(88)90125-7journal_volume
6pub_type
杂志文章abstract：:Perfusion magnetic resonance imaging (MRI) is a promising non-invasive technique providing insights regarding the brain's microvascular architecture in vivo. The scalar perfusion metrics can be used for quantitative diagnostics of various brain abnormalities, in particular, in the stroke cases and tumours. However, co...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2018.11.007
更新日期：2019-04-01 00:00:00
abstract：:The goal of this study was to develop and evaluate high-resolution magnetic resonance spectroscopic imaging (MRSI) utilizing the gains in signal-to-noise ratio (SNR) provided by combining higher magnetic field with high-sensitivity phased-array (PA) coils. We investigated the maximum improvement in spatial resolution ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2005.10.019
更新日期：2006-01-01 00:00:00
abstract：:We determined whether the accuracy of magnetic resonance angiography (MRA) in the peripheral run-off vessels can be improved by using contrast-enhanced (CE) three-dimensional (3D) technique in comparison to electrocardiograph (ECG)-triggered two-dimensional (2D) time-of-flight (TOF) technique. In a prospective study 2...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(98)00078-2
更新日期：1998-10-01 00:00:00
abstract：:Until recently, NMR imaging with intermolecular multiple-quantum coherences (iMQCs) has been based on the acquisition of a single echo. In vivo studies of iMQC image contrast would greatly benefit from a method that could acquire several orders of quantum coherence during the same acquisition. This would enable compar...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2004.10.019
更新日期：2004-12-01 00:00:00
abstract：:The ability to evaluate empirical diffusion MRI acquisitions for quality and to correct the resulting imaging metrics allows for improved inference and increased replicability. Previous work has shown promise for estimation of bias and variance of generalized fractional anisotropy (GFA) but comes at the price of compu...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2019.03.021
更新日期：2019-06-01 00:00:00
abstract：:Quantification of magnetic resonance (MR)-based relaxation parameters of tendons and ligaments is challenging due to their very short transverse relaxation times, requiring application of ultra-short echo-time (UTE) imaging sequences. We quantify both T1 and T2* in the quadriceps and patellar tendons of healthy volunt...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2019.07.015
更新日期：2019-11-01 00:00:00
abstract：:An efficient method for obtaining longitudinal relaxation time (T1) maps is based on acquiring two spoiled gradient recalled echo (SPGR) images in steady states with different flip angles, which has also been extended, with additional acquisitions, to obtain a tissue water content (M0) map. Several factors, including ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2013.08.001
更新日期：2013-12-01 00:00:00
abstract：:In magnetic resonance elastography (MRE), shear waves at a certain frequency are encoded through bipolar gradients that switch polarity at a controlled encoding frequency and are offset in time to capture wave propagation using a controlled sampling frequency. In brain MRE, there is a possibility that the mechanical a...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2011.09.017
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:3D Time-of-flight (TOF) magnetic resonance angiography is commonly used for vascular analyses. A quantification of longitudinal morphological changes usually requires the registration of TOF image sequences acquired at different time points. The aim of this study was to evaluate the precision of different 3D ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2014.08.011
更新日期：2014-12-01 00:00:00
abstract：PURPOSE:To implement and evaluate interleaved blip-up, blip-down, non-segmented 3D echo planar imaging (EPI) with pseudo-continuous arterial spin labeling (pCASL) and post-processing for reduced susceptibility artifact cerebral blood flow (CBF) maps. MATERIALS AND METHODS:3D EPI non-segmented acquisition with a pCASL ...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2017.08.011
更新日期：2017-12-01 00:00:00
abstract：:Two parallel imaging methods used for first-pass myocardial perfusion imaging were compared in terms of signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR) and image artifacts. One used adaptive Time-adaptive SENSitivity Encoding (TSENSE) and the other used GeneRalized Autocalibrating Partially Parallel Acquisi...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2006.10.012
更新日期：2007-06-01 00:00:00
abstract：PURPOSE:The purpose was to study the effect of estrogen deficiency on contrast agent diffusion into intervertebral disc in a rat model. MATERIALS AND METHODS:Seven-month-old female Sprague-Dawley rats were used. Fourteen rats had ovariectomy, and nine rats had sham surgery. Magnetic resonance imaging (MRI) of sagittal...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.01.001
更新日期：2012-06-01 00:00:00
abstract：:We present the case of a 44-year-old man who complained of cervical pain. He was treated with physiotherapy and analgetics. Because of persistent pain, computed tomography (CT) scan and MRI were performed. They revealed an osteolytic destruction of the fourth cervical vertebra. The patient was treated surgically for r...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章,评审
doi：10.1016/j.mri.2004.01.006
更新日期：2004-05-01 00:00:00
abstract：:The subthalamic nucleus (STN) is one of the most common stimulation targets for treating Parkinson's disease using deep brain stimulation (DBS). This procedure requires precise placement of the stimulating electrode. Common practice of DBS implantation utilizes microelectrode recording to locate the sites with the cor...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.02.006
更新日期：2012-06-01 00:00:00
abstract：:Before it is possible to use MR imaging to investigate changes in the hippocampus in disease processes such as epilepsy and memory disorders, it is imperative that normal variations are defined. Using specific anatomic locations, we evaluated the hippocampi of 29 normal volunteers with coronal MR studies. Mild variati...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(91)90035-k
更新日期：1991-01-01 00:00:00
abstract：:The magnetic resonance imaging (MRI) features of two cases of malignant lymphoproliferative disease involving skeletal muscle are presented. In both cases involved muscles were quantitatively and subjectively hypointense to fat on T1-weighted spin echo images, hypointense or isointense on T2-weighted spin echo images,...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(92)90522-2
更新日期：1992-01-01 00:00:00
abstract：:Currently, the North American symptomatic carotid endarterectomy trial, European carotid surgery trial, and common carotid method are used to measure the carotid stenosis for determining candidates for carotid endarterectomy using the projection angiography from different modalities such as digital subtraction angiogr...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2004.01.007
更新日期：2004-04-01 00:00:00
abstract：:A quantitative analysis of the dependence of water proton relaxation on water content in randomly packed beds of Sephadex is undertaken. A combination of Osmotic and Capillary theory is used to describe the morphological changes occurring in the packed beds as the water content is lowered. At each water content the wa...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(94)92032-x
更新日期：1994-01-01 00:00:00
abstract：:Articular cartilage thickness is of relevance in various fields in diagnostics and biomedical research. In view of recent improvements of MR cartilage imaging a computational method has been developed for three-dimensional determination of cartilage thickness from tomographic datasets. A correction algorithm that comp...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(97)00012-x
更新日期：1997-01-01 00:00:00
abstract：:A new magnetic resonance imaging technique was applied to the Taylor-Couette and spiral Poiseuille (Taylor-Couette with superposed mean axial flux) flows for the first time. The experimental technique is a combination of spatial tagging methods and a snapshot FLASH imaging sequence, which allows the full-field visuali...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(99)00121-6
更新日期：2000-02-01 00:00:00
abstract：:We report the first application of a novel diffusion-based MRI method, called diffusional kurtosis imaging (DKI), to investigate changes in brain tissue microstructure in patients with mild cognitive impairment (MCI) and AD and in cognitively intact controls. The subject groups were characterized and compared in terms...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2013.02.008
更新日期：2013-07-01 00:00:00
abstract：:Phantoms for evaluation of nuclear magnetic resonance (NMR) imaging systems were made from water-based agarose gels, according to a standard procedure herein described. Copper sulfate (CuSO4) was included in the gels to further affect their proton relaxation characteristics. The proton relaxation rates of each batch o...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(86)91068-4
更新日期：1986-01-01 00:00:00
abstract：:Blood oxygenation level-dependent (BOLD) functional magnetic resonance imaging (fMRI) is currently the dominant technique for non-invasive investigation of brain functions. One of the challenges with BOLD fMRI, particularly at high fields, is compensation for the effects of spatiotemporally varying magnetic field inho...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2009.07.005
更新日期：2010-02-01 00:00:00
abstract：AIM:Matrix metalloproteases (MMPs) expression and their inhibitors (TIMPs) play an important role in tumor physiopathology, so we investigated the relationship between the magnetic resonance (MR) and MMPs/TIMPs expression by breast carcinomas. MATERIALS AND METHODS:MRI parameters of 64 breast carcinomas were investiga...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2016.04.005
更新日期：2016-10-01 00:00:00
abstract：INTRODUCTION:Glioma is the most common type of the primary CNS tumor. Radiotherapy is an important treatment measure after surgery. However, its highly invasive character is the main reason of postoperative recurrence. The aim of the study was to probe the correlation between the invasion ability and the metabolite cha...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2016.05.009
更新日期：2016-10-01 00:00:00
abstract：:It has been shown recently that quantitative T2-maps may be measured by acquisition of a series of at least eight T2-weighted SNAPSHOT FLASH images. These measurements require a relaxation delay of 10-15 s after each T2-weighted image for the complete relaxation of the spin system. This results in long measuring times...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/0730-725x(95)00004-z
更新日期：1995-01-01 00:00:00
abstract：:Quantitative analysis has tremendous but mostly unrealized potential in healthcare to support objective and accurate interpretation of the clinical imaging. In 2008, the National Cancer Institute began building the Quantitative Imaging Network (QIN) initiative with the goal of advancing quantitative imaging in the con...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2012.05.001
更新日期：2012-11-01 00:00:00
abstract：:Functional MR (fMR) imaging techniques based on blood oxygenation level dependent (BOLD) effects were developed and applied to a rat brain tumor model to evaluate the potential utility of the method for characterizing tumor growth and regression following treatment. Rats bearing 9L brain tumors in situ were imaged dur...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/s0730-725x(98)00208-2
更新日期：1999-05-01 00:00:00
abstract：:Lipomatous tumors of the uterus are unusual, benign neoplasms seen in postmenopausal women. Although many of the mixed-type cases such as lipoleiomyoma and fibrolipoma have been reported, pure uterine lipomas are extremely rare. In the literature, a few cases with pure uterine lipoma have been reported. We first prese...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2007.01.116
更新日期：2007-10-01 00:00:00
abstract：:The chain dynamics of short-chain perfluoropolyether melts confined in Vycor nanoporous media has been characterized by field cycling nuclear magnetic resonance relaxometry and the dipolar correlation effect. The slowdown of motions under confinement, leading to larger residual dipolar couplings, has been probed by lo...
journal_title：Magnetic resonance imaging
pub_type： 杂志文章
doi：10.1016/j.mri.2006.11.018
更新日期：2007-05-01 00:00:00
