Abstract:
:Purpose To assess a volume-weighted voxel-based multiparametric (MP) clustering method as an imaging biomarker to differentiate recurrent glioblastoma from delayed radiation necrosis. Materials and Methods The institutional review board approved this retrospective study and waived the informed consent requirement. Seventy-five patients with pathologic analysis-confirmed recurrent glioblastoma (n = 42) or radiation necrosis (n = 33) who presented with enlarged contrast material-enhanced lesions at magnetic resonance (MR) imaging after they completed concurrent chemotherapy and radiation therapy were enrolled. The diagnostic performance of the total MP cluster score was determined by using the area under the receiver operating characteristic curve (AUC) with cross-validation and compared with those of single parameter measurements (10% histogram cutoffs of apparent diffusion coefficient [ADC10] or 90% histogram cutoffs of normalized cerebral blood volume and initial time-signal intensity AUC). Results Receiver operating characteristic curve analysis showed that an AUC for differentiating recurrent glioblastoma from delayed radiation necrosis was highest in the total MP cluster score and lowest for ADC10 for both readers. The total MP cluster score had significantly better diagnostic accuracy than any single parameter (corrected P = .001-.039 for reader 1; corrected P = .005-.041 for reader 2). The total MP cluster score was the best predictor of recurrent glioblastoma (cross-validated AUCs, 0.942-0.946 for both readers), with a sensitivity of 95.2% for reader 1 and 97.6% for reader 2. Conclusion Quantitative analysis with volume-weighted voxel-based MP clustering appears to be superior to the use of single imaging parameters to differentiate recurrent glioblastoma from delayed radiation necrosis. © RSNA, 2017 Online supplemental material is available for this article.
journal_name
Radiologyjournal_title
Radiologyauthors
Yoon RG,Kim HS,Koh MJ,Shim WH,Jung SC,Kim SJ,Kim JHdoi
10.1148/radiol.2017161588subject
Has Abstractpub_date
2017-10-01 00:00:00pages
206-213issue
1eissn
0033-8419issn
1527-1315journal_volume
285pub_type
杂志文章相关文献
RADIOLOGY文献大全abstract::In a phantom and in 37 patients, a simple laser guidance system for computed tomography (CT)-guided procedures used the software program of the CT scanner and a laser beam mounted on the CT gantry without need for additional software or components. The skin entry point and angulation of the target path were determined...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.194.1.7997570
更新日期:1995-01-01 00:00:00
abstract::Two patients with pneumothorax had ventilation-perfusion studies to rule out the possibility of pulmonary embolism; the presence of air in the pleural space was not known to the authors when the study was analyzed. A typical ventilatory pattern characterized by small volume difference at total lung capacity followed b...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/129.1.119
更新日期:1978-10-01 00:00:00
abstract::Cortical fissuring, a well-recognized radiographic sign of osteomyelitis, represents spread of infection through the haversian system with osteoclastic bone resorption. In the proper clinical setting this finding may be recognized before there is other evidence of bone destruction or periosteal reaction. Three cases a...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.141.1.7027310
更新日期:1981-10-01 00:00:00
abstract::The authors developed a colostomy appliance for use during barium-enema examinations. It is 8 cm in diameter and 4 cm in height, and is made of acrylic resins. With the use of this device, 21 patients were fluoroscopically examined through the stoma; good contrast views of the lower intestinal tract were obtained in a...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/133.1.241
更新日期:1979-10-01 00:00:00
abstract:PURPOSE:To optimize detection and diagnosis of breast lesions with contrast-enhanced magnetic resonance (MR) imaging. MATERIALS AND METHODS:A three-dimensional fast low-angle shot pulse sequence was used for a group comparison consisting of 76 high-dose (0.16 mmol gadopentetate dimeglumine per kilogram of body weight)...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.191.3.8184040
更新日期:1994-06-01 00:00:00
abstract:PURPOSE:To describe a benign nodular lesion in the peripheral zone (PZ) of the prostate gland. MATERIALS AND METHODS:In 1,087 patients, the features of 722 focal lesions in the PZ or central zone of the prostate on transrectal ultrasound (TRUS) scans were retrospectively compared with histologic findings in biopsy sam...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.189.3.7694310
更新日期:1993-12-01 00:00:00
abstract::The ultrasonic appearance of the normal and abnormal fetal spine before 20 weeks' gestation was reviewed in 121 pregnances. A model was constructed to establish the mechanism of production in the various configurations seen. The relative roles of ultrasonography, alpha fetoprotein assay, and fetoscopy in the diagnosis...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/132.1.131
更新日期:1979-07-01 00:00:00
abstract::Quality control in diagnostic radiography begins with production of predictable exposures. The authors describe a technique which permits determination of the variation of mR/mAs for the entire diagnostic range of times and currents in only about 1 hour. The mR/mAs in newly installed units has been shown to vary by as...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/122.2.489
更新日期:1977-02-01 00:00:00
abstract::Esophageal motor disorders are best evaluated with manometry, which, however, is time-consuming and not generally available. The authors prospectively investigated the yield of videofluoroscopy in detection of esophageal motor disorders in comparison with that of manometry. Eighty-eight patients with dysphagia, globus...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.185.2.1410360
更新日期:1992-11-01 00:00:00
abstract::In 15 osteosarcomas and six Ewing sarcomas, response to preoperative chemotherapy was assessed with magnetic resonance (MR) imaging without and with gadolinium diethylenetriaminepentaacetic acid (DTPA) enhancement and with dynamic Gd-DTPA studies, and the results were compared with the scintigraphic findings. All stud...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.175.3.2188300
更新日期:1990-06-01 00:00:00
abstract::Eight patients with liver disease and seriously abnormal blood coagulation underwent biopsy of the liver performed through a percutaneously introduced sheath, followed by embolization of the biopsy track with steel coils. In all cases the biopsy procedure produced profuse bleeding through the sheath. However, the blee...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.169.1.3420270
更新日期:1988-10-01 00:00:00
abstract::Purpose To investigate the performance of a deep convolutional neural network (DCNN) model in the staging of liver fibrosis using gadoxetic acid-enhanced hepatobiliary phase magnetic resonance (MR) imaging. Materials and Methods This retrospective study included patients for whom input data (hepatobiliary phase MR ima...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2017171928
更新日期:2018-04-01 00:00:00
abstract::Upon review, 25 cases of Brodie abscess demonstrated a radiological spectrum not previously appreciated. One third of the lesions were diaphyseal in location, and 50% had associated cortical thickening, while 40% showed a stimulated periosteal reaction, and 20% contained sequestra. The variable radiological appearance...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/132.1.15
更新日期:1979-07-01 00:00:00
abstract::The potential of a new nonionic gadolinium complex--gadodiamide injection--to (a) allow distinction between reperfused and occlusive infarction and (b) enable differentiation between reperfused reversible and irreversible myocardial injury was investigated. Three groups of rats were used: 10 with reversibly reperfused...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.182.3.1535880
更新日期:1992-03-01 00:00:00
abstract:PURPOSE:To evaluate whether exposure to strong static magnetic fields (SMFs), of up to 10 T, affects the growth and cycle distribution of and the micronucleus formation in monolayered Chinese hamster ovary CHO-K1 cells. MATERIALS AND METHODS:The authors developed a system to expose cultured cells to strong SMFs immedi...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2243011300
更新日期:2002-09-01 00:00:00
abstract::We report success with CT guided percutaneous catheter drainage of deep neck abscesses. The cost efficacy and decreased morbidity of percutaneous catheter drainage has been proved in abdominal and retroperitoneal abscess management, and CT for diagnosis of deep neck infections is well established. The logical applicat...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.152.1.6729120
更新日期:1984-07-01 00:00:00
abstract::Purpose To determine the effects of patient age and comorbidity level on life expectancy (LE) benefits associated with imaging follow-up of Bosniak IIF renal cysts and pancreatic side-branch (SB) intraductal papillary mucinous neoplasms (IPMNs). Materials and Methods A decision-analytic Markov model to evaluate LE ben...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2018171701
更新日期:2018-05-01 00:00:00
abstract::Perfusion computed tomography (CT) is a relatively new technique that allows rapid qualitative and quantitative evaluation of cerebral perfusion by generating maps of cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT). The technique is based on the central volume principle (CBF = CBV/M...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/radiol.2313021488
更新日期:2004-06-01 00:00:00
abstract::A new nonionic dimeric contrast medium (CM), iodixanol, was intravenously administered to 40 healthy male volunteers in doses of 0.3-1.2 g of iodine per kilogram of body weight, nonionic monomeric iopamidol and iopentol were administered to 20 others, and the renal effects were studied up to 120 hours after administra...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.182.2.1732960
更新日期:1992-02-01 00:00:00
abstract:PURPOSE:To evaluate the accuracy of ultrasonography (US) in determining the anatomic variations in the first extensor compartment of the wrist. MATERIALS AND METHODS:Approval from the anatomic donations department was obtained. The first extensor compartment of the wrist of 40 nonembalmed cadaveric forearms (15 male a...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.10092265
更新日期:2010-11-01 00:00:00
abstract:PURPOSE:To assess the relationship between heart valve history and susceptibility artifacts at magnetic resonance (MR) imaging of the brain in patients with Björk-Shiley convexoconcave (BSCC) valves. MATERIALS AND METHODS:MR images of the brain were obtained in 58 patients with prosthetic heart valves: 20 patients had...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2303021619
更新日期:2004-03-01 00:00:00
abstract::Four nodules, visualized with 99mTc pertechnetate at 20-60 min., were not visualized with either 123I or 131I at 2-4 hours. Each nodule was demonstrated to have autonomy of function in excess of surrounding normal tissue when imaged with radioiodine after TSH suppression. Rapid turnover of an iodine moiety would seem ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/119.3.737
更新日期:1976-06-01 00:00:00
abstract::Twenty-nine patients with known or suspected malignancy were studied with identical T1-weighted (spin echo [SE] and inversion recovery [IR]) and T2-weighted SE magnetic resonance (MR) imaging at 0.5 and 1.5 T to evaluate the relative sensitivities of these sequences for detecting focal hepatic lesions. At 0.5 T, 98 le...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.174.1.2152980
更新日期:1990-01-01 00:00:00
abstract::Purpose To assess the impact of a patient experience improvement program on national ranking in patient experience in a large academic radiology department. Materials and Methods This Health Insurance Portability and Accountability Act-compliant study was exempted from institutional review board approval. After initia...
journal_title:Radiology
pub_type: 杂志文章,多中心研究
doi:10.1148/radiol.2019182307
更新日期:2019-04-01 00:00:00
abstract::Purpose To determine the effect of radiation dose and iterative reconstruction (IR) on noise, contrast, resolution, and observer-based detectability of subtle hypoattenuating liver lesions and to estimate the dose reduction potential of the IR algorithm in question. Materials and Methods This prospective, single-cente...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2017161736
更新日期:2017-09-01 00:00:00
abstract:PURPOSE:To retrospectively compare the diagnostic yield and complications associated with the use of short versus long needle paths for computed tomography (CT)-guided biopsy of small subpleural lung lesions. MATERIALS AND METHODS:The study was approved by the institutional review board, and the requirement for inform...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.2342031423
更新日期:2005-02-01 00:00:00
abstract::In the assessment of vertebral bone mineral density (BMD) with quantitative computed tomography, accuracy is limited by systematic errors caused by beam-hardening effects and unknown marrow and fat concentrations in trabecular bone. Reproducibility depends on precise repositioning of the patient, selection of the regi...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.164.2.3602380
更新日期:1987-08-01 00:00:00
abstract::This paper reviews some of the fundamental technical and diagnostic problems in clinical uroradiology, such as (a) the reason for the obstructive nephrogram; (b) why high-dose urography gives better studies than low-dose; (c) why the Trueta phenomenon has not been demonstrated in man; (d) the case for an intrarenal ar...
journal_title:Radiology
pub_type: 杂志文章,评审
doi:10.1148/116.2.259
更新日期:1975-08-01 00:00:00
abstract::The authors conducted a multivariate analysis of the prognostic factors in 96 patients with early glottic cancer treated by radiation therapy. Of these, 73 had T1 and 23 had T2 tumor. The primary tumor was controlled in 82% of T1 and 74% of T2 lesions. Actuarial five-year survival rates were 87% for T1 and 74% for T2....
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiology.149.1.6611940
更新日期:1983-10-01 00:00:00
abstract:PURPOSE:To compare changes in urinary viscosity in the renal tubules following administration of a high-viscosity iso-osmolar contrast agent (iodixanol) to that observed following administration of a less viscous, higher osmolar contrast agent (iopromide) in anesthetized rats. MATERIALS AND METHODS:A total of 43 rats ...
journal_title:Radiology
pub_type: 杂志文章
doi:10.1148/radiol.10091485
更新日期:2010-08-01 00:00:00