Mesoscale-duration activated states gate spiking in response to fast rises in membrane voltage in the awake brain.

abstract：:Sindbis viruses have been widely used in neurobiology to express a variety of genes in cultured neurons, in cultured slices, and in vivo. They provide fast onset and high levels of expression of foreign genes, but the expression is limited to a short time window due to a shut-off of host protein synthesis. We have use...

journal_title：Journal of neurophysiology

authors： Jeromin A,Yuan LL,Frick A,Pfaffinger P,Johnston D

更新日期：2003-10-01 00:00:00

abstract：:1. Intracellular recordings were made from layer VI pyramidal cells in in vitro slice preparations of the cat motor cortex (area 4 gamma). Layer VI pyramidal cells were identified morphologically by intracellular injection of biocytin. 2. Of 22 layer VI pyramidal cells examined, single action potentials were followed ...

journal_title：Journal of neurophysiology

authors： Kang Y,Kayano F

更新日期：1994-08-01 00:00:00

abstract：:Sleep disturbances are prevalent in clinical anxiety, but it remains unclear whether they are cause and/or consequence of this condition. Fear conditioning constitutes a valid laboratory model for the acquisition of normal and pathological anxiety. To explore the relationship between disturbed sleep and anxiety in mor...

journal_title：Journal of neurophysiology

authors： Peters AC,Blechert J,Sämann PG,Eidner I,Czisch M,Spoormaker VI

更新日期：2014-09-15 00:00:00

abstract：:CA1 inhibitory interneurons at the stratum lacunosum-moleculare and radiatum junction (LM/RAD-INs) display subthreshold membrane potential oscillations (MPOs) involving voltage-dependent Na(+) and A-type K(+) currents. LM/RAD-INs also express other voltage-gated K(+) currents, although their properties and role in MPO...

journal_title：Journal of neurophysiology

authors： Morin F,Haufler D,Skinner FK,Lacaille JC

更新日期：2010-06-01 00:00:00

abstract：:Adaptation of movement may be driven by the difference between planned and actual motor performance, or the difference between expected and actual sensory consequences of movement. To identify how the nervous system differentially uses these signals, we asked: does motor adaptation occur when movement errors are irrel...

journal_title：Journal of neurophysiology

authors： Schaefer SY,Shelly IL,Thoroughman KA

更新日期：2012-02-01 00:00:00

abstract：:Fast-spiking (FS) interneurons provide the main route of feedforward inhibition from cortex to spiny projection neurons in the striatum. A steep current-firing frequency curve and a dense local axonal arbor suggest that even small excitatory inputs could translate into powerful feedforward inhibition, although such an...

journal_title：Journal of neurophysiology

authors： Kotaleski JH,Plenz D,Blackwell KT

更新日期：2006-01-01 00:00:00

abstract：:Single-unit recordings were made from layer II/III anterior piriform cortex (aPCX) neurons in adult Wistar rats to examine odor response patterns to unilaterally and bilaterally delivered stimuli. Isoamyl acetate odor stimulation was presented either unilaterally through tubes inserted into the external nares, or bila...

journal_title：Journal of neurophysiology

authors： Wilson DA

更新日期：1997-07-01 00:00:00

abstract：:Unitary discharge patterns (peristimulus time histograms or PSTH) and synaptic events were studies with intracellular recording techniques in 164 cat cochlear nucleus cells to steady-frequency tone bursts 250 ms in duration. There were four response types defined on the basis of the shape of the discharge patterns to ...

journal_title：Journal of neurophysiology

authors： Britt R,Starr A

更新日期：1976-01-01 00:00:00

abstract：:The whole cell patch-clamp technique in combination with the slice preparation was used to investigate the electrophysiological properties of pigeon semicircular canal sensory and supporting cells. These properties were also characterized in regenerating neuroepithelia of pigeons preinjected with streptomycin to kill ...

journal_title：Journal of neurophysiology

authors： Masetto S,Correia MJ

更新日期：1997-10-01 00:00:00

abstract：:Humans quickly and sophisticatedly correct their movements in response to changes in the world, such as when reaching to a target that abruptly changes its location. The vigor of these movement corrections is time-dependent, increasing if the time left to make the correction decreases, which can be explained by optima...

journal_title：Journal of neurophysiology

authors： Oostwoud Wijdenes L,van Beers RJ,Medendorp WP

更新日期：2019-09-01 00:00:00

abstract：:It is well established that orderly patterns of motor neuron activity, muscle recruitment, and limb movement are generated in chicks during motility by embryonic day (E)9, the midpoint in embryonic development. However, our recent work suggests that some attributes of motility, such as the rhythm of repetitive limb mo...

journal_title：Journal of neurophysiology

authors： Bradley NS,Jahng DY

更新日期：2003-09-01 00:00:00

abstract：:1. Whether complex (C) cells are the only truly texture-sensitive units in the cat's primary visual cortex remains controversial. In view of the strong physiological significance of having putatively only one class of cells sensitive to visual noise in the striate cortex, we reinvestigated this issue. Sensitivities of...

journal_title：Journal of neurophysiology

authors： Casanova C,Savard T,Nordmann JP,Molotchnikoff S,Minville K

更新日期：1995-09-01 00:00:00

abstract：:1. A quantal analysis of transmission at the identified molluscan synapse, V2-RPr1, was performed during development. The study was intended to determine the pre- and postsynaptic contributions to the marked changes in transmitter release described in the previous report. 2. The success of the quantal analysis was pre...

journal_title：Journal of neurophysiology

authors： Pawson PA,Chase R

更新日期：1988-12-01 00:00:00

abstract：:In quadrupeds, the dorsal-side-up body orientation during standing is maintained due to a postural system that is driven by feedback signals coming mainly from limb mechanoreceptors. In caudally decerebrated (postmammillary) rabbits, the efficacy of this system is considerably reduced. In this paper, we report that th...

journal_title：Journal of neurophysiology

authors： Zelenin PV,Hsu LJ,Orlovsky GN,Deliagina TG

更新日期：2012-06-01 00:00:00

abstract：:We studied gamma-aminobutyric acid (GABA)-mediated currents in short-term cultured dorsal unpaired median (DUM) neurons of cockroach Periplaneta americana using the whole cell patch-clamp technique in symmetrical chloride solutions. All DUM neurons voltage-clamped at -50 mV displayed inward currents (I(GABA)) when 10(...

journal_title：Journal of neurophysiology

authors： Alix P,Grolleau F,Hue B

更新日期：2002-06-01 00:00:00

abstract：:Experimental and clinical evidence indicates that pain can affect cognitive processes, but the cortical networks involved in pain-cognition interactions are unclear. In this study, we determined the effect of pain on the activity of cortical areas involved in cognition acting as a whole (i.e., a network). Subjects und...

journal_title：Journal of neurophysiology

authors： Seminowicz DA,Davis KD

更新日期：2007-05-01 00:00:00

abstract：:1. Neuron-specific expression of alternately spliced exons of the gene encoding the Phe-Met-Arg-Phe-NH2 (FMRFamide) family of neuropeptides and the role of encoded peptides in synaptic transmission were examined in an identified cardiorespiratory interneuron, the visceral white interneuron (VWI), in the snail Lymnaea....

journal_title：Journal of neurophysiology

authors： Skingsley DR,Bright K,Santama N,van Minnen J,Brierley MJ,Burke JF,Benjamin PR

更新日期：1993-03-01 00:00:00

abstract：:The activity of the crayfish abdominal postural motoneurons and their associated neurons (the accessory neuron(s) and the MRO(1)) were examined with the aid of techniques for the analysis of simultaneously recorded spike trains. A means of reliably identifying the spikes of the individual motoneurons based on their re...

journal_title：Journal of neurophysiology

authors： Sokolove PG,Tatton WG

更新日期：1975-03-01 00:00:00

abstract：:1. Plasticity at the connections between sensory neurons and their follower cells in Aplysia has been used extensively as a model system to examine mechanisms of simple forms of learning. Earlier studies have concluded that serotonin (5-HT) is a key modulatory transmitter and that it exerts its short-term actions via ...

journal_title：Journal of neurophysiology

authors： Sugita S,Goldsmith JR,Baxter DA,Byrne JH

更新日期：1992-08-01 00:00:00

abstract：:1. We have identified putative histaminergic neurons in the central nervous system of Aplysia californica by light-microscopic autoradiography after uptake of [3H]histamine and by immunohistochemistry with the use of an antibody specific for histamine. 2. In the cerebral ganglion cells previously shown to contain hist...

journal_title：Journal of neurophysiology

authors： Elste A,Koester J,Shapiro E,Panula P,Schwartz JH

更新日期：1990-09-01 00:00:00

abstract：:For human locomotion, varying environments require adjustments of the motor system. We asked whether age affects gait balance recovery adaptation, its retention over months, and the transfer of adaptation to an untrained reactive balance task. Healthy adults (26 young, 27 middle-aged, and 25 older; average ages 24, 52...

journal_title：Journal of neurophysiology

authors： König M,Epro G,Seeley J,Potthast W,Karamanidis K

更新日期：2019-11-01 00:00:00

abstract：:A spherical approximation technique is presented that affords a mathematical characterization of a virtual space receptive field (VSRF) based on first-spike latency in the auditory cortex of cat. Parameterizing directional sensitivity in this fashion is much akin to the use of difference-of-Gaussian (DOG) functions fo...

journal_title：Journal of neurophysiology

authors： Jenison RL,Reale RA,Hind JE,Brugge JF

更新日期：1998-11-01 00:00:00

abstract：:The mechanisms and impact of correlated, or synchronous, firing among pairs and groups of neurons are under intense investigation throughout the nervous system. A ubiquitous circuit feature that can give rise to such correlations consists of overlapping, or common, inputs to pairs and populations of cells, leading to ...

journal_title：Journal of neurophysiology

authors： Barreiro AK,Thilo EL,Shea-Brown E

更新日期：2012-09-01 00:00:00

abstract：:In the spinal cord, the monoamine neurotransmitter norepinephrine, which is released mainly from fibers descending from the dorsal pons, has major modulatory effects on nociception and locomotor rhythms. To map the spatial and temporal patterns of this release, changes in monoamine level were examined in laminae I-VII...

journal_title：Journal of neurophysiology

authors： Hentall ID,Mesigil R,Pinzon A,Noga BR

更新日期：2003-06-01 00:00:00

abstract：:1. The influence of viewing distance on disparity selectivity was investigated in area V1 of behaving monkeys. While the animals performed a fixation task, cortical cells were recorded extracellularly in the foveal representation of the visual field. Disparity selectivity was assessed by using static random dot stereo...

journal_title：Journal of neurophysiology

authors： Trotter Y,Celebrini S,Stricanne B,Thorpe S,Imbert M

更新日期：1996-11-01 00:00:00

abstract：:The rostral ventromedial medulla (RVM) modulates nociception through changes in the activity of two classes of neuron, ON- and OFF-cells. The activity of these neurons is regulated, in part, by input from the periaqueductal gray (PAG). The objective of this study was to determine whether PAG-mediated antinociception i...

journal_title：Journal of neurophysiology

authors： Tortorici V,Morgan MM

更新日期：2002-10-01 00:00:00

abstract：:1. The individual joint rotations of a movement sequence might be controlled either by a central motor plan or by motion-dependent (i.e., kinesthetic) sensory input. Most previous research has focused on how the nervous system uses central motor plans to control movement sequences. This study examined how the nervous ...

journal_title：Journal of neurophysiology

authors： Cordo PJ

更新日期：1990-01-01 00:00:00

abstract：:Because vagal and sympathetic inputs activate upper cervical spinal neurons, we hypothesized that stimulation of the esophagus would activate C(1)-C(2) neurons. This study examined responses of C(1)-C(2) spinal neurons to cervical and thoracic esophageal distension (CED, TED) and afferent pathways for CED and TED inpu...

journal_title：Journal of neurophysiology

authors： Qin C,Chandler MJ,Jou CJ,Foreman RD

更新日期：2004-05-01 00:00:00

abstract：:The pre-Bötzinger complex (preBötC) underlies inspiratory rhythm generation. As a result of network interactions, preBötC neurons burst synchronously to produce rhythmic premotor inspiratory activity. Each inspiratory burst consists of action potentials (APs) on top of a 10- to 20-mV synchronous depolarization lasting...

journal_title：Journal of neurophysiology

authors： Morgado-Valle C,Fernandez-Ruiz J,Lopez-Meraz L,Beltran-Parrazal L

更新日期：2015-02-15 00:00:00

abstract：:Dopaminergic modulation produces a variety of functional changes in the principal cell of the striatum, the medium spiny neuron (MSN). Using a 189-compartment computational model of a ventral striatal MSN, we simulated whole cell D1- and D2-receptor-mediated modulation of both intrinsic (sodium, calcium, and potassium...

journal_title：Journal of neurophysiology

authors： Moyer JT,Wolf JA,Finkel LH

更新日期：2007-12-01 00:00:00