The Emerging Role of Pimavanserin in the Management of Parkinson's Disease Psychosis.

abstract：BACKGROUND:National guidelines and initiatives have promoted the use of angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin receptor blockers (ARBs) for patients with diabetes. The University of Arizona Medication Management Center (UA-MMC) is contracted by Medicare health plans, pharmacy benefit managers ...

journal_title：Journal of managed care & specialty pharmacy

authors： Hurwitz JT,Grizzle AJ,Augustine J,Rehfeld R,Wild A,Abraham I

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND:Opioid pain relievers can be highly effective in providing relief for patients suffering from pain. At the same time, prescription opioid abuse, dependence, overdose, and poisoning (hereinafter "abuse") have become a national public health concern. Opioid abuse is also costly: previous estimates of the annua...

journal_title：Journal of managed care & specialty pharmacy

authors： Kirson NY,Scarpati LM,Enloe CJ,Dincer AP,Birnbaum HG,Mayne TJ

更新日期：2017-04-01 00:00:00

abstract：:BACKGROUND: Basal insulin is often recommended as the initial therapy for patients with type 2 diabetes who require insulin treatment. Adequate adherence is critical to diabetes management, yet suboptimal insulin adherence has been reported. Second-generation long-acting (SGLA) insulin has higher dosing flexibility an...

journal_title：Journal of managed care & specialty pharmacy

authors： Zhang H,Barner JC,Moczygemba LR,Rascati KL

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Adjuvant trastuzumab treatment is administered to early stage breast cancer patients in physician office (POV) or hospital outpatient (HOP) settings. OBJECTIVE:To identify treatment patterns, utilization, and costs by site of care (POV vs. HOP) of patients with adjuvant treatment of breast cancer with trast...

journal_title：Journal of managed care & specialty pharmacy

authors： Parthan A,Santos E,Becker L,Small A,Lalla D,Brammer M,Teitelbaum A

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Allergy immunotherapy (AIT) is the only available treatment that alters the natural course of allergies and has possible disease-modifying effects. AIT is administered primarily via subcutaneous injection delivered in a physician's office. Few studies have been conducted in the United States or Canada to eva...

journal_title：Journal of managed care & specialty pharmacy

authors： Blume SW,Yeomans K,Allen-Ramey F,Smith N,Kim H,Lockey RF,Nichol MB

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Oral pharmacological treatment for overactive bladder (OAB) consists of antimuscarinics and the beta-3 adrenergic agonist mirabegron. Antimuscarinic adverse events (AEs) such as dry mouth, constipation, and blurry vision can result in frequent treatment discontinuation rates, leaving part of the OAB populati...

journal_title：Journal of managed care & specialty pharmacy

authors： Perk S,Wielage RC,Campbell NL,Klein TM,Perkins A,Posta LM,Yuran T,Klein RW,Ng DB

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Adherence to antiretrovirals (ARVs) is critical to achieving durable virologic suppression. OBJECTIVE:To investigate risk factors of poor adherence and the effect of suboptimal adherence on health care resource utilization (HCRU) and costs in Medicaid patients. METHODS:A retrospective longitudinal study wa...

journal_title：Journal of managed care & specialty pharmacy

authors： Dunn K,Lafeuille MH,Jiao X,Romdhani H,Emond B,Woodruff K,Pesa J,Tandon N,Lefebvre P

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:Despite multiple treatment options, the prognosis of pulmonary arterial hypertension (PAH) remains poor. PAH patients experience a high economic burden due to comorbidities, hospitalizations, and medication costs. Although combination therapy has been shown to reduce hospitalizations, the relationship betwee...

journal_title：Journal of managed care & specialty pharmacy

authors： Burger CD,Ozbay AB,Lazarus HM,Riehle E,Montejano LB,Lenhart G,White RJ

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Natalizumab disease-modifying therapy for relapsing-remitting multiple sclerosis (MS) is efficacious in randomized controlled trials. Few studies have estimated the association between real-world natalizumab persistence behavior and relapse-related outcomes. OBJECTIVES:To (a) examine the impact of using nat...

journal_title：Journal of managed care & specialty pharmacy

authors： McQueen RB,Livingston T,Vollmer T,Corboy J,Buckley B,Allen RR,Nair K,Campbell JD

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Employers have increased efforts to engage employees in health and wellness programs. Providing employees with incentives to participate in these programs has been shown to improve overall enrollment and engagement. One program that has had challenges with enrollment and engagement is medication therapy mana...

journal_title：Journal of managed care & specialty pharmacy

authors： Tomaszewski D,Cernohous T,Vaidyanathan R

更新日期：2017-11-01 00:00:00

abstract：:The inclusion of pharmacists on care teams has been shown to improve clinical and economic health outcomes. However, a significant barrier to the widespread incorporation of pharmacists into care teams is the ability to financially support the salary of the pharmacist. A mechanism to improve the ability of pharmacists...

journal_title：Journal of managed care & specialty pharmacy

authors： Dietrich E,Gums JG

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Poor medication adherence is a predictor of poor health outcomes, especially in populations with chronic diseases. Although several self-reported measures of medication adherence exist, the scope of each is limited.  OBJECTIVE:To identify barriers to medication adherence in order to facilitate effective del...

journal_title：Journal of managed care & specialty pharmacy

authors： Hincapie AL,Taylor AM,Boesen KP,Warholak T

更新日期：2015-05-01 00:00:00

abstract：:The ever-vulnerable medication supply chain is being further strained by the COVID-19 pandemic. Pharmacists in all settings, including managed care, will need to prepare for a potential exacerbation of existing and new drug shortages in the midst of unprecedented crisis. We summarize the major issues, discuss potentia...

journal_title：Journal of managed care & specialty pharmacy

authors： Shuman AG,Fox ER,Unguru Y

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The impact of formulary management strategies on utilization and expenditures in overactive bladder (OAB) treatment has not been extensively investigated. In 2013, step therapy (ST) policies for 2 branded OAB treatments, mirabegron and fesoterodine, were removed from Humana Medicare Advantage Prescription Dr...

journal_title：Journal of managed care & specialty pharmacy

authors： Abbass IM,Caplan EO,Ng DB,Kristy R,Schermer CR,Bradt P,Collins JM,Chan WM,Suehs BT

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:In recent years, comparative effectiveness tools and methods have evolved to assist health care decision makers in identifying optimal therapies. In-person training programs on comparative effectiveness research may be helpful in understanding and applying this information. OBJECTIVE:To provide a follow-up ...

journal_title：Journal of managed care & specialty pharmacy

authors： Augustine J,Warholak TL,Hines LE,Sun D,Brown M,Hurwitz J,Taylor AM,Brixner D,Cobaugh DJ,Schlaifer M,Malone DC

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Geographic variation in the use of prescription drugs, particularly those deemed harmful by the FDA, may lead to variation in patient exposure to adverse drug events. One such drug is the glucose-lowering drug rosiglitazone, for which the FDA issued a safety alert on May 21, 2007, following the publication o...

journal_title：Journal of managed care & specialty pharmacy

authors： Ahuja V,Sohn MW,Birge JR,Syverson C,Budiman-Mak E,Emanuele N,Cooper JM,Huang ES

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Several authors have hypothesized that adverse drug events (ADEs) upon switching from reference biologics to biosimilar products are related to the nocebo effect. However, a thorough and current review of the existing literature has not been conducted. OBJECTIVE:To evaluate if patient and/or physician knowl...

journal_title：Journal of managed care & specialty pharmacy

authors： Odinet JS,Day CE,Cruz JL,Heindel GA

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:This study is an evaluation of a discharge intervention that occurred in multiple hospitals across Maryland. In this program, patients received medications at their bedside before discharge with the goal of reducing the risk of primary nonadherence to prescribed medications. OBJECTIVE:To test if the interve...

journal_title：Journal of managed care & specialty pharmacy

authors： Segal JB,Apfel A,Brotman DJ,Shermock KM,Clark JM

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Acromegaly is a chronic disorder characterized by excess growth hormone secretion and elevated insulin-like growth factor-1 levels most often caused by a pituitary adenoma. Clinical presentation of the disease includes coarsening of the facial features, soft-tissue swelling of the hands and feet, and overgro...

journal_title：Journal of managed care & specialty pharmacy

authors： Placzek H,Xu Y,Mu Y,Begelman SM,Fisher M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Prostacyclins play an important role in the management of pulmonary arterial hypertension (PAH). Intravenous prostacyclin was the first disease-specific treatment for patients with PAH. Subcutaneous and nonparenteral (oral or inhaled) formulations have subsequently become available. However, data are lacking...

journal_title：Journal of managed care & specialty pharmacy

authors： Burger CD,Pruett JA,Lickert CA,Berger A,Murphy B,Drake W 3rd

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Accurate estimates of the effects of cost sharing on adherence to medications prescribed for use together, also called concurrent adherence, are important for researchers, payers, and policymakers who want to reduce barriers to adherence for chronic condition patients prescribed multiple medications concurre...

journal_title：Journal of managed care & specialty pharmacy

authors： Sacks NC,Burgess JF,Cabral HJ,McDonnell ME,Pizer SD

更新日期：2015-08-01 00:00:00

abstract：DISCLOSURES:No funding contributed to the writing of this commentary. Brandsema reports consulting for Alexion, Audentes, AveXis, Biogen, Cytokinetics, PTC Therapeutics, Sarepta, and WaVe and has received research funding as a site investigator from Alexion, AveXis, Biogen, CSL Behring, Cytokinetics, Fibrogen, Pfizer, ...

journal_title：Journal of managed care & specialty pharmacy

authors： Brandsema JF

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:In recent years, there have been a number of pharmacological innovations for Crohn's disease (CD), a difficult-to-treat condition, including new treatment philosophies (e.g., top-down therapy) and new therapeutic options in terms of the agent and the route of administration. Three anti-tumor necrosis factor ...

journal_title：Journal of managed care & specialty pharmacy

authors： Liu J,Sylwestrzak G,Ruggieri AP,DeVries A

更新日期：2015-07-01 00:00:00

abstract：DISCLOSURES:No funding was involved in the writing of this letter. Outside of the submitted work, Hiligsmann has received research grants through institution from Amgen, Radius Health, UCB, and Teva/Theramex. Reginster has received research grants and/or consulting fees from Servier, Novartis, Negma, Lilly, Wyeth, Amge...

journal_title：Journal of managed care & specialty pharmacy

authors： Hiligsmann M,Reginster JY,Silverman S

更新日期：2020-03-01 00:00:00

abstract：DISCLOSURES:No funding was required for this project. The authors are or have been members of the Format Executive Committee. ...

journal_title：Journal of managed care & specialty pharmacy

authors： Watkins JB,Sullivan SD,Sampsel E,Fullerton DSP,Graff JS,Fry RN,Lee J,Tam IM,Avey SG

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Adherence to treatment is correlated with treatment success in chronic myeloid leukemia (CML). CVS Specialty explored novel methods to improve adherence in this population to ensure optimal adherence and lower the risk of unsuccessful treatment. One novel program explored involved an interactive 2-way clinic...

journal_title：Journal of managed care & specialty pharmacy

authors： Sawicki C,Friend KE,Patel R,Polinski JM,Singh S

更新日期：2019-11-01 00:00:00

abstract：:We write to comment on a recently published study by Delea et al. in the January 2015 issue of JMCP that evaluated the cost-effectiveness (CE) of sunitinib (SU) versus pazopanib (PAZ) as first-line treatment for metastatic renal cell carcinoma (mRCC) from a U.S. third-party payer perspective.1 This analysis was based ...

journal_title：Journal of managed care & specialty pharmacy

authors： Benedict A,Ramaswamy K,Sandin R

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:The introduction of anti-vascular endothelial growth factor (anti-VEGF) drugs to ophthalmology has revolutionized the treatment of neovascular age-related macular degeneration (nAMD). Despite this significant progress, gaps and challenges persist in the diagnosis of nAMD, initiation of treatment, and managem...

journal_title：Journal of managed care & specialty pharmacy

authors： Wykoff CC,Clark WL,Nielsen JS,Brill JV,Greene LS,Heggen CL

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:The accountable care organization (ACO) is an innovative health care delivery model centered on value-based care. ACOs consisting of primary care providers are increasingly becoming commonplace in practice; however, medication management remains suboptimal. PROGRAM DESCRIPTION:As experts in medication manag...

journal_title：Journal of managed care & specialty pharmacy

authors： Joseph T,Hale GM,Eltaki SM,Prados Y,Jones R,Seamon MJ,Moreau C,Gernant SA

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Research describing patient experience and outcomes with extended half-life recombinant factor VIII (EHL rFVIII) outside of clinical trials is limited. Real-world rFVIII consumption studies, when people with hemophilia A (PWHA) switch from standard half-life (SHL) to EHL rFVIII, may help payers and clinician...

journal_title：Journal of managed care & specialty pharmacy

authors： Aledort L,Milligan S,Watt M,Booth J

更新日期：2020-04-01 00:00:00