Abstract:
:The goal of this study is to demonstrate the feasibility of a novel non-coplanar-arc optimization algorithm (CyberArc). This method aims to reduce the delivery time of conventional CyberKnife treatments by allowing for continuous beam delivery. CyberArc uses a 4 step optimization strategy, in which nodes, beams, and collimator sizes are determined, source trajectories are calculated, intermediate radiation models are generated, and final monitor units are calculated, for the continuous radiation source model. The dosimetric results as well as the time reduction factors for CyberArc are presented for 7 prostate and 2 brain cases. The dosimetric quality of the CyberArc plans are evaluated using conformity index, heterogeneity index, local confined normalized-mutual-information, and various clinically relevant dosimetric parameters. The results indicate that the CyberArc algorithm dramatically reduces the treatment time of CyberKnife plans while simultaneously preserving the dosimetric quality of the original plans.
journal_name
Phys Med Bioljournal_title
Physics in medicine and biologyauthors
Kearney V,Cheung JP,McGuinness C,Solberg TDdoi
10.1088/1361-6560/aa6f92subject
Has Abstractpub_date
2017-06-26 00:00:00pages
5777-5789issue
14eissn
0031-9155issn
1361-6560journal_volume
62pub_type
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