Abstract:
OBJECTIVE:To evaluate orthodontic tooth movement (OTM) in rats treated with two types of bisphosphonates (BPs), alendronate sodium (A) and zoledronic acid (Z). DESIGN:In all, 15 male Wistar rats were randomly divided into three groups. Group OTM+A: orthodontic tooth movement and subcutaneous administration of alendronate sodium (2.5 mg/kg); Group OTM+Z: orthodontic tooth movement and subcutaneous administration of zoledronic acid (0.02 mg/kg), and Group OTM: orthodontic tooth movement and subcutaneous injection of saline. The BPs were administered once a day during 25 days before OTM started and during 10 days of OTM. The left upper first molar was moved with a stainless-steel closed coil spring which delivered an initial force of 0.4N. OTM was measured with a digital caliper comparing the moved and the contralateral side. The histomorphometric analysis counted the number of osteoclasts, inflammatory cells, blood vessels and fibroblasts (n/104 m2 ) in periodontal ligament (PDL) of the distobuccal root. RESULTS:A reduction of 58.3% of OTM was found in Group OTM+A and 99.6% in Group OTM+Z, when compared with Group OTM. There was a significant decrease of osteoclasts and inflammatory cells in BP-treated groups. Blood vessels and fibroblastic cells decreased mainly in Group OTM+Z. CONCLUSION:Alendronate sodium and zoledronic acid have similar effects on the periodontal tissue during orthodontic treatment in rats. Especially, zoledronic acid can affect orthodontic tooth movement.
journal_name
Orthod Craniofac Resjournal_title
Orthodontics & craniofacial researchauthors
Franzoni JS,Soares FMP,Zaniboni E,Vedovello Filho M,Santamaria MP,Dos Santos GMT,Esquisatto MAM,Felonato M,Mendonca FAS,Franzini CM,Santamaria M Jrdoi
10.1111/ocr.12192subject
Has Abstractpub_date
2017-08-01 00:00:00pages
164-169issue
3eissn
1601-6335issn
1601-6343journal_volume
20pub_type
杂志文章abstract:OBJECTIVES:to evaluate the accuracy of cone beam computed tomography (CBCT) for volumetric measurement of teeth, using micro-computed tomography (Micro-CT) as the reference standard. SETTING AND SAMPLE POPULATION:The Department of Orthodontics at Sichuan University. The sample consisted of 27 maxillary and mandibular ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2011.01525.x
更新日期:2011-11-01 00:00:00
abstract:OBJECTIVES:To review the historic context for digital imaging in dentistry and to outline the fundamental issues related to digital imaging modalities. CONTEXT:Digital dental X-ray images can be achieved by scanning analog film radiographs (secondary capture), with photostimulable phosphors, or using solid-state detec...
journal_title:Orthodontics & craniofacial research
pub_type: 历史文章,杂志文章
doi:10.1034/j.1600-0544.2003.231.x
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:This investigation evaluates the evidence of case-based reasoning (CBR) in providing additional information on the prediction of future Class III craniofacial growth. SETTINGS AND SAMPLE POPULATION:The craniofacial characteristics of 104 untreated Class III subjects (7-17 years of age), monitored with two la...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12466
更新日期:2021-01-08 00:00:00
abstract:OBJECTIVES:To test the following two hypotheses: 1) different types of retainers result in distinct levels of biomarkers in gingival crevicular fluid (GCF) and 2) the retainer bonded to all mandibular anterior teeth induces more detrimental outcomes to the periodontium. SETTING AND SAMPLE POPULATION:The Department of ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12129
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVES:To determine whether the use of chewing gum reduced the impact and pain of fixed orthodontic appliances. SETTING AND SAMPLE POPULATION:The Orthodontic Department of the Charles Clifford Dental Hospital, Sheffield, UK. Fifty-seven patients aged 18 years or younger and who were about to start fixed orthodonti...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1601-6343.2012.01546.x
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVE:The role of oestrogen in craniofacial growth still remains unclear. Therefore, the present study aimed to assess the effect of oestrogen deficiency on maxilla and mandible dimensions. SETTING AND SAMPLE POPULATION:The study was conducted at the Department of Pediatric Dentistry at the School of Dentistry of ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12376
更新日期:2020-08-01 00:00:00
abstract::The skin and the oral mucosa act as a barrier against the external environment. Loss of this barrier function causes dehydration and a high risk of infection. For the treatment of extensive skin wounds such as in severe burns, autologous skin for transplantation is often not available in sufficient amounts. Reconstruc...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2009.01475.x
更新日期:2010-02-01 00:00:00
abstract:OBJECTIVES:To explore asymmetry values of antimeric deciduous tooth crown dimensions in three types of twins: monozygotic (MZ), dizygotic same-sex (DZ) and opposite-sex (OS) vs. single-born controls. SETTING AND SAMPLE POPULATION:Mesiodistal and labio-lingual crown dimensions of second deciduous molars and mesiodistal...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12122
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:To investigate the effects of diabetes on orthodontic tooth movement and orthodontically induced root resorption in rats. SETTING AND SAMPLE POPULATION:Twenty-three 10-week-old male Sprague-Dawley rats divided into control (n = 7), diabetes (n = 9), and diabetes + insulin (n = 7) groups. MATERIALS AND METHO...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12117
更新日期:2016-05-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare treatment outcomes with different maxillary protraction methods in patients with skeletal Class III malocclusion resulting from maxillary retrognathia. SETTING AND SAMPLE POPULATION:A total of 55 individuals consisting of 29 females and 26 males with a mean age of 11.4 ± ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12389
更新日期:2020-11-01 00:00:00
abstract:OBJECTIVE:To clarify the correlation between variations in maximum occlusal force and the maxillofacial skeletal pattern in subjects with malocclusion using a compact device. DESIGN:Three hundred and fifty patients (150 males 200 females) with malocclusion were included. The male and female subjects were divided into ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2007.00405.x
更新日期:2007-11-01 00:00:00
abstract:OBJECTIVES:To measure skull thickness in a group of subjects with skeletal Class II and a group with skeletal Class III malocclusion and compare these results with a group with Class I occlusion. SETTING AND SAMPLE POPULATION:Department of Orthodontics, School of Dentistry, University of Copenhagen. The Class II group...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2008.00434.x
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVES:To evaluate root surface changes and resorption following toothborne rapid maxillary expansion (RME) using cone beam computed tomography (CBCT). SETTING AND SAMPLE POPULATION:The Department of Orthodontics at The University of Texas Health Science Center. Twenty-four consecutively treated patients (mean age...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12069
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVES:The purpose of this study was to investigate the effects of reduced masticatory function on midline suture growth and morphology in growing pigs. SETTING AND SAMPLE POPULATION:The sample was 20 pigs separated into two dietary groups and raised at the Department of Anthropology, Harvard University. Midline s...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2010.01483.x
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To compare subjective pain experience and oral health-related quality of life (OH-QoL) in treated and untreated subjects over the first 3 months of fixed appliance therapy. SETTING AND SAMPLE POPULATION:The Department of Orthodontics, School of Medicine and Dentistry. One hundred and twenty-four subjects age...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12044
更新日期:2014-08-01 00:00:00
abstract::The mental health of children, adolescents, and adults with orofacial clefts has been studied extensively. Outcomes of interest have included parental adaptation, parent-child attachment, child development, intellectual and academic outcomes, behavioral adaptation, and quality of life. The literature sheds light on me...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2007.00394.x
更新日期:2007-08-01 00:00:00
abstract:AIMS AND OBJECTIVES:Documentation of dental and orthodontic implications of osteoglophonic dysplasia (OGD). SETTINGS AND PARTICIPANTS:Case report describing oral and dental manifestations of a female with OGD, aged 39 years, who was first documented three decades ago. RESULTS:This rare genetic disorder manifests with...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2006.00369.x
更新日期:2006-08-01 00:00:00
abstract::This essay briefly considers some underlying concerns about the direction of clinical research in orthodontics. The field is viewed from a personal perspective as things are now, as they are becoming, and as I believe they should be. ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2004.00292.x
更新日期:2004-08-01 00:00:00
abstract:OBJECTIVES:To study treatment-related factors for external root resorption during orthodontic tooth movement. DESIGN:An experimental animal study. SETTING AND SAMPLE POPULATION:Department of Orthodontics and Oral Biology, University Medical Centre Nijmegen, The Netherlands. Twenty-four young adult beagle dogs. EXPER...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2004.00283.x
更新日期:2004-05-01 00:00:00
abstract::Antimicrobial orthodontic adhesives aim to reduce white spot lesions' incidence in orthodontic patients, but they should not jeopardizing its properties. Systematic review and meta-analysis were performed to answer the question whether the association of antimicrobial agents with orthodontic adhesives compromises its ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,meta分析,评审
doi:10.1111/ocr.12100
更新日期:2016-02-01 00:00:00
abstract::We have developed a cone beam X-ray computed tomography (CT) system to make more accurate three-dimensional (3-D) images for diagnosis of dento-maxillofacial region. The developed system has sufficient spatial resolution, resolution of 3-D images and image distortion for diagnosis of dentomaxillofacial region. ...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1034/j.1600-0544.2003.249.x
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To investigate the effect of lithium on alveolar bone formation during orthodontic retention in rats. MATERIALS AND METHODS:After 2 weeks of orthodontic tooth movement (OTM), 42 8-week-old male Wistar rats were randomly divided into two orthodontic retention groups: one without (control) and the other with L...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12190
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:To compare the predicted tooth width measurements of permanent canine and premolars from Tanaka-Johnston regression equations and Moyers probability tables with the in situ measurements in a sample of Peruvian adolescents. DESIGN:Cross-sectional. SETTING AND SAMPLE POPULATION:Trujillo, Peru; 248 dental cas...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1034/j.1600-0544.2003.03251.x
更新日期:2003-08-01 00:00:00
abstract::Repair of tooth supporting alveolar bone defects caused by periodontal and peri-implant tissue destruction is a major goal of reconstructive therapy. Oral and craniofacial tissue engineering has been achieved with limited success by the utilization of a variety of approaches such as cell-occlusive barrier membranes, b...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2005.00352.x
更新日期:2005-11-01 00:00:00
abstract:OBJECTIVES:To examine the potential role of next-generation sequencing (NGS) and genetic testing to guide preventive care in dental enamel disorders using publicly available databases to access the frequency of deleterious alleles in AMTN, AMLEX and ENAM, associated with amelogenesis imperfecta (AI). SETTING AND SAMPL...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12266
更新日期:2019-05-01 00:00:00
abstract:OBJECTIVES:Literature is poor of data about the occlusion in children affected by neurofibromatosis type 1 (NF1). This case-control study investigated the occlusal traits in a group of children with NF1. SETTING AND SAMPLE POPULATION:A hundred and fifteen children with NF1 were enrolled; non-NF1 controls were sequenti...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12108
更新日期:2016-02-01 00:00:00
abstract::The aim of this review was to systematically appraise the evidence on aligner mechanics and forces and moments generated across difference types of aligners. In vitro- laboratory studies for model simulated tooth movement with aligners. Database searches within Medline via Pubmed, Cochrane Central Register of Controll...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,meta分析,评审
doi:10.1111/ocr.12333
更新日期:2019-11-01 00:00:00
abstract:OBJECTIVES:Three-dimensional evaluation of skeletal mandibular changes following Herbst appliance treatment. SETTING AND SAMPLE POPULATION:Retrospective case-control study, based on a sample size calculation. Twenty-five pubertal patients treated with Herbst appliance (HAG), and 25 matched Class II patients who receiv...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/ocr.12154
更新日期:2017-05-01 00:00:00
abstract:UNLABELLED:AUTHOR: Shen G Objective -This review was compiled to explore the role of type X collagen in growth, development and remodeling of articular cartilage by elucidating the linkage between the synthesis of this protein and the phenotypic changes in chondrogenesis and the onset of endochondral ossification. DES...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章,评审
doi:10.1111/j.1601-6343.2004.00308.x
更新日期:2005-02-01 00:00:00
abstract:PURPOSE:To experimentally determine the effects of increased surgical trauma on the rates of tooth movement and apical root resorption. Two surgical techniques for rapid protraction of multi-rooted teeth in foxhound dogs immediately following premolar extraction were compared. METHODS:Split-mouth design to randomly as...
journal_title:Orthodontics & craniofacial research
pub_type: 杂志文章
doi:10.1111/j.1601-6343.2010.01494.x
更新日期:2010-08-01 00:00:00