Prevalence, Pathogenesis, Diagnosis, and Management of Microscopic Colitis.

Abstract:

:Microscopic colitis (MC), which is comprised of lymphocytic colitis and collagenous colitis, is a clinicopathological diagnosis that is commonly encountered in clinical practice during the evaluation and management of chronic diarrhea. With an incidence approaching the incidence of inflammatory bowel disease, physician awareness is necessary, as diagnostic delays result in a poor quality of life and increased health care costs. The physician faces multiple challenges in the diagnosis and management of MC, as these patients frequently relapse after successful treatment. This review article outlines the risk factors associated with MC, the clinical presentation, diagnosis and histologic findings, as well as a proposed treatment algorithm. Prospective studies are required to better understand the natural history and to develop validated histologic endpoints that may be used as end points in future clinical trials and serve to guide patient management.

journal_name

Gut Liver

journal_title

Gut and liver

authors

Gentile N,Yen EF

doi

10.5009/gnl17061

subject

Has Abstract

pub_date

2018-05-15 00:00:00

pages

227-235

issue

3

eissn

1976-2283

issn

2005-1212

pii

gnl17061

journal_volume

12

pub_type

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