Abstract:
:Microscopic colitis (MC), which is comprised of lymphocytic colitis and collagenous colitis, is a clinicopathological diagnosis that is commonly encountered in clinical practice during the evaluation and management of chronic diarrhea. With an incidence approaching the incidence of inflammatory bowel disease, physician awareness is necessary, as diagnostic delays result in a poor quality of life and increased health care costs. The physician faces multiple challenges in the diagnosis and management of MC, as these patients frequently relapse after successful treatment. This review article outlines the risk factors associated with MC, the clinical presentation, diagnosis and histologic findings, as well as a proposed treatment algorithm. Prospective studies are required to better understand the natural history and to develop validated histologic endpoints that may be used as end points in future clinical trials and serve to guide patient management.
journal_name
Gut Liverjournal_title
Gut and liverauthors
Gentile N,Yen EFdoi
10.5009/gnl17061subject
Has Abstractpub_date
2018-05-15 00:00:00pages
227-235issue
3eissn
1976-2283issn
2005-1212pii
gnl17061journal_volume
12pub_type
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