Abstract:
:Foot pressure ulcers are a common complication of diabetes because of patient's lack of sensitivity due to neuropathy. Deep pressure ulcers appear internally when pressures applied on the foot create high internal strains nearby bony structures. Monitoring tissue strains in persons with diabetes is therefore important for an efficient prevention. We propose to use personalized biomechanical foot models to assess strains within the foot and to determine the risk of ulcer formation. Our workflow generates a foot model adapted to a patient's morphology by deforming an atlas model to conform it to the contours of segmented medical images of the patient's foot. Our biomechanical model is composed of rigid bodies for the bones, joined by ligaments and muscles, and a finite element mesh representing the soft tissues. Using our registration algorithm to conform three datasets, three new patient models were created. After applying a pressure load below these foot models, the Von Mises equivalent strains and "cluster volumes" (i.e. volumes of contiguous elements with strains above a given threshold) were measured within eight functionally meaningful foot regions. The results show the variability of both location and strain values among the three considered patients. This study also confirms that the anatomy of the foot has an influence on the risk of pressure ulcer.
journal_name
Med Eng Physjournal_title
Medical engineering & physicsauthors
Bucki M,Luboz V,Perrier A,Champion E,Diot B,Vuillerme N,Payan Ydoi
10.1016/j.medengphy.2016.04.017subject
Has Abstractpub_date
2016-09-01 00:00:00pages
845-53issue
9eissn
1350-4533issn
1873-4030pii
S1350-4533(16)30073-Xjournal_volume
38pub_type
杂志文章abstract::In our previous studies, we have introduced model-based "functional biomarkers" or "physiomarkers" of cerebral hemodynamics that hold promise for improved diagnosis of early-stage Alzheimer's disease (AD). The advocated methodology utilizes subject-specific data-based dynamic nonlinear models of cerebral hemodynamics ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2014.02.025
更新日期:2014-05-01 00:00:00
abstract::Computational fluid dynamics (CFD) simulations quantifying thoracic aortic flow patterns have not included disturbances from the aortic valve (AoV). 80% of patients with aortic coarctation (CoA) have a bicuspid aortic valve (BAV) which may cause adverse flow patterns contributing to morbidity. Our objectives were to d...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2012.07.015
更新日期:2013-06-01 00:00:00
abstract::Despite its medical relevance, accurate recognition of sedentary (sitting and lying) and dynamic activities (e.g. standing and walking) remains challenging using a single wearable device. Currently, trunk-worn wearable systems can differentiate sitting from standing with moderate success, as activity classifiers often...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2014.01.001
更新日期:2014-06-01 00:00:00
abstract::Segmentation of medical images is very important for clinical research and diagnosis, leading to a requirement for robust automatic methods. This paper reports on the combined use of a neural network (a multilayer perceptron, MLP) and active contour model ('snake') to segment structures in magnetic resonance (MR) imag...
journal_title:Medical engineering & physics
pub_type: 临床试验,杂志文章
doi:10.1016/s1350-4533(03)00137-1
更新日期:2004-01-01 00:00:00
abstract::Reconstruction of segmental defects in the mandible remains a challenge for maxillofacial surgery. The use of porous scaffolds is a potential method for repairing these defects. Now, additive manufacturing techniques provide a solution for the fabrication of porous scaffolds with specific geometrical shapes and comple...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2017.06.015
更新日期:2017-09-01 00:00:00
abstract::A ligamentous, nonlinear, sliding contact, three-dimensional finite element (FE) model of L2-L3 complex was developed to investigate the biomechanical effect of laminectomy with and without facetectomy. The L2-L3 FE model was validated against experimental study under various physiological loadings and found to match ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2003.11.006
更新日期:2004-04-01 00:00:00
abstract::This study aimed at developing a method for automated electrocardiography (ECG) artifact detection and removal from trunk electromyography signals. Independent Component Analysis (ICA) method was applied to the simulated data set of ECG-corrupted surface electromyography (SEMG) signals. Independent Components (ICs) co...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2010.05.007
更新日期:2010-10-01 00:00:00
abstract::The formation of pressure ulcers can be exacerbated by a breakdown in the integrity of the patient's skin caused by poor maintenance of the skin microclimate. Patient support systems (PSSs-specialised beds, mattresses, chairs, cushions and pads) play an important role in the dissipation of heat and moisture away from ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(00)00003-5
更新日期:1999-12-01 00:00:00
abstract::The potential for a simple, non-invasive measure of respiratory effort based on the pulse oximeter signal - the photoplethysmogram or 'pleth' - was investigated in a pilot study. Several parameters were developed based on a variety of manifestations of respiratory effort in the signal, including modulation changes in ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2016.12.010
更新日期:2017-03-01 00:00:00
abstract::A field-usable sleepiness tester could reduce sleepiness related accidents. 15 subjects' postural steadiness was measured with a Nintendo(®) Wii Fit balance board every hour for 24 h. Body sway was quantified with complexity index, CI, and the correlation between CI and alertness predicted by a three-process model of ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2013.08.007
更新日期:2013-12-01 00:00:00
abstract::Based on an adaptive genetic fuzzy clustering algorithm, a derived fuzzy knowledge model is proposed for quantitatively estimating the systolic arterial pressure (SAP), heart rate (HR), and bispectral index (BIS) using 12 patients and it validates them according to pharmacological reasoning. Also, a genetic proportion...
journal_title:Medical engineering & physics
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.medengphy.2005.04.023
更新日期:2006-03-01 00:00:00
abstract::Although the precise causes of Sudden Infant Death Syndrome (SIDS) are still unclear there is evidence to suggest that hypoxaemia may be a contributory factor. Transcutaneous oxygen monitors can be used but are unsatisfactory for young babies in the home. As an alternative approach, respiratory patterns can be studied...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/1350-4533(94)90005-1
更新日期:1994-01-01 00:00:00
abstract::Selected adsorption efficiency of a molecule in solution in a microchannel is strongly influenced by the convective/diffusive mass transport phenomena that supply the target molecule to the adsorption surface. In a standard microchannel with a rectangular cross section, laminar flow regime limits the fluid mixing, thu...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2017.07.003
更新日期:2017-10-01 00:00:00
abstract::Characterising circulatory dysfunction and choosing a suitable treatment is often difficult and time consuming, and can result in a deterioration in patient condition, or unsuitable therapy choices. A stable minimal model of the human cardiovascular system (CVS) is developed with the ultimate specific aim of assisting...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2003.10.001
更新日期:2004-03-01 00:00:00
abstract::Acetabular fractures potentially account for up to half of all pelvic fractures, while pelvic fractures potentially account for over one-tenth of all human bone fractures. This is the first biomechanical study to assess acetabular fracture fixation using plates versus cables in the presence of a total hip arthroplasty...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2017.06.004
更新日期:2017-08-01 00:00:00
abstract:INTRODUCTION:A notable characteristic of bariatric surgery is the frequent manipulation of the bowel. The bowel is large, delicate, flexible, and has a natural lubricant on the tissue surface. Therefore the bowel is difficult to grasp and manipulate. Vacuum technique is commonly used in industry for all types of graspi...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2011.11.014
更新日期:2012-10-01 00:00:00
abstract::A method aimed at the real-time monitoring of muscular fatigue was implemented and optimized. The method is based on an estimate of the complex covariance function in order to evaluate, in real time, the mean frequency of the myoelectric signal spectrum. Real-time implementation is guaranteed by a recursive computatio...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(99)00049-1
更新日期:1999-05-01 00:00:00
abstract::In laboratory animals as well as in human beings a depth of anaesthesia, where the subject has no pain or recall of events from the surgery, should be provided. Haemodynamic parameters such as heart rate and blood pressure are not a guarantee for an optimal depth of anaesthesia, especially when using neuromuscular blo...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(98)00089-7
更新日期:1998-12-01 00:00:00
abstract::We investigated whether automatic control of a hand grasp neuroprosthesis by means of signals from natural sensors in the skin of the index finger can mimic the natural control of grasp force in an important task of daily living, namely eating. We designed a simulated eating task with the same ratio of rest and activi...
journal_title:Medical engineering & physics
pub_type: 临床试验,杂志文章
doi:10.1016/j.medengphy.2004.03.002
更新日期:2004-07-01 00:00:00
abstract::An 'instantaneous' optimal filter is presented for improving the signal-to-noise ratio in averaged electrocardiograms (ECGs). The filter design is based on a simple model that accounts for correlation across the ensemble of beats but ignores correlation in time. Another property of the model is that the noise level is...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(96)00069-0
更新日期:1997-04-01 00:00:00
abstract::This paper describes a non-invasive human brain-actuated robotic arm experiment, which allows remote writing. In the local environment, the participant decides on an arbitrary word to transmit. A mental speller interface is then used to select the letters. A robot arm placed in the remote environment writes the word o...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2011.06.005
更新日期:2011-12-01 00:00:00
abstract::The investigation presented in this paper has attempted to study, from a fluid dynamics point of view, the consequences of the presence of a stent on the flow of blood. The method adopted is mainly by numerical simulation using a finite element technique, but visualization experiments and an analytical study have also...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(00)00072-2
更新日期:2000-10-01 00:00:00
abstract::The aim of this study was to develop a technique for analyzing and visualizing the regional, three-dimensional signal intensity distribution of articular cartilage in MR images, as a potential surrogate marker of structural or biochemical alterations in early osteoarthritis. Exemplary MR-images of human patellae were ...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/s1350-4533(02)00006-1
更新日期:2002-04-01 00:00:00
abstract::Whole-body vibration experiments with subjects under vertical vibration were performed to examine and evaluate effects of backrest inclination on vibration transmitted through seats to the human body by using biodynamic response parameters represented by apparent mass (APMS) and vibration power absorption (VPA). The b...
journal_title:Medical engineering & physics
pub_type: 临床试验,杂志文章
doi:10.1016/j.medengphy.2010.02.007
更新日期:2010-07-01 00:00:00
abstract::Tripolar systems have been implanted to reduce the risk of recurrent dislocation. However, there is little known about the dynamic behavior of tripolar hip endoprostheses under daily life conditions and achieved joint stability. Hence, the objective of this biomechanical study was to examine the in vivo dynamics and d...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2013.09.007
更新日期:2014-01-01 00:00:00
abstract::The reliability of internal joint moment calculation in gait analysis during daily living activities is fundamental for clinical decisions based on joint function. This calculation, obtained by means of the inverse dynamics, depends on several modelling factors, such as assumptions on the segments and on the relevant ...
journal_title:Medical engineering & physics
pub_type: 临床试验,杂志文章
doi:10.1016/j.medengphy.2004.12.002
更新日期:2005-07-01 00:00:00
abstract::This study presents a specimen-specific C2-C7 cervical spine finite element model that was developed using multiblock meshing techniques. The model was validated using in-house experimental flexibility data obtained from the cadaveric specimen used for mesh development. The C2-C7 specimen was subjected to pure continu...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2010.03.001
更新日期:2010-06-01 00:00:00
abstract::We present a finite element based simulation and analysis method to describe the spatial extent of stimulation and the effects of electrode-tissue interactions in subretinal prostheses. In particular, we estimate the threshold stimulation current needed to depolarise and evoke action potentials in the ganglion cells t...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2011.01.015
更新日期:2011-07-01 00:00:00
abstract::We developed a device for an objective measurement of non-nutritive sucking (NNS). NNS is newborns' spontaneous action that is a predictor of their neural system development and can be adopted as an intervention to train oral feeding skills in preterms. Two miniaturized digital pressure sensors were embedded into a co...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2015.12.013
更新日期:2016-04-01 00:00:00
abstract::Investigations of compressive frequency, duty cycle, or waveform during CPR are typically rooted in animal research or computer simulations. Our goal was to generate a mechanical model incorporating alternate stiffness settings and an integrated blood flow system, enabling defined, reproducible comparisons of CPR effi...
journal_title:Medical engineering & physics
pub_type: 杂志文章
doi:10.1016/j.medengphy.2017.02.005
更新日期:2017-05-01 00:00:00