Abstract:
:The mechanism underlying brain region organization for motor control in humans remains poorly understood. In this functional magnetic resonance imaging (fMRI) study, right-handed volunteers were tasked to maintain unilateral foot movements on the right and left sides as consistently as possible. We aimed to identify the similarities and differences between brain motor networks of the two conditions. We recruited 18 right-handed healthy volunteers aged 25 ± 2.3 years and used a whole-body 3T system for magnetic resonance (MR) scanning. Image analysis was performed using SPM8, Conn toolbox and Brain Connectivity Toolbox. We determined a craniocaudally distributed, mirror-symmetrical modular structure. The functional connectivity between homotopic brain areas was generally stronger than the intrahemispheric connections, and such strong connectivity led to the abovementioned modular structure. Our findings indicated that the interhemispheric functional interaction between homotopic brain areas is more intensive than the interaction along the conventional top-down and bottom-up pathways within the brain during unilateral limb movement. The detected strong interhemispheric horizontal functional interaction is an important aspect of motor control but often neglected or underestimated. The strong interhemispheric connectivity may explain the physiological phenomena and effects of promising therapeutic approaches. Further accurate and effective therapeutic methods may be developed on the basis of our findings.
journal_name
Front Hum Neuroscijournal_title
Frontiers in human neuroscienceauthors
Wei P,Zhang Z,Lv Z,Jing Bdoi
10.3389/fnhum.2017.00366subject
Has Abstractpub_date
2017-07-12 00:00:00pages
366issn
1662-5161journal_volume
11pub_type
杂志文章abstract::Functional imaging studies using BOLD contrasts have consistently reported activation of the supplementary motor area (SMA) both during motor and internal timing tasks. Opposing findings, however, have been shown for the modulation of beta oscillations in the SMA. While movement suppresses beta oscillations in the SMA...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2017.00582
更新日期:2017-11-30 00:00:00
abstract::Dementia researchers around the world prioritize the urgent need for sensitive measurement tools that can detect cognitive and functional change at the earliest stages of Alzheimer's disease (AD). Sensitive indicators of underlying neural pathology assist in the early detection of cognitive change and are thus importa...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2018.00124
更新日期:2018-04-09 00:00:00
abstract::Background: Transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS) have been proposed as a new therapeutic way to enhance the cognition of patients with dementia. However, serious methodological limitations appear to affect the estimates of their efficacy. We reviewed the stimulatio...
journal_title:Frontiers in human neuroscience
pub_type:
doi:10.3389/fnhum.2020.00179
更新日期:2020-05-25 00:00:00
abstract::The frequency-following response (FFR) is an auditory evoked potential (AEP) that follows the periodic characteristics of a sound. Despite being a widely studied biosignal in auditory neuroscience, the neural underpinnings of the FFR are still unclear. Traditionally, FFR was associated with subcortical activity, but r...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2020.00250
更新日期:2020-07-08 00:00:00
abstract::Diffusion tensor imaging (DTI) is a powerful MRI technique that can be used to estimate both the microstructural integrity and the trajectories of white matter pathways throughout the central nervous system. This fiber tracking (aka, "tractography") approach is often carried out using anatomically-defined seed points ...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2015.00585
更新日期:2015-11-03 00:00:00
abstract::Motor control and adaptation are multi-determinate processes with complex interactions. This is reflected for example in the ambiguous nature of interactions during sequential adaptation of reaching under kinematics and dynamics perturbations. It has been suggested that perturbations based on the same kinematic parame...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/neuro.09.065.2009
更新日期:2010-01-04 00:00:00
abstract::Indirect speech acts-responding "I forgot to wear my watch today" to someone who asked for the time-are ubiquitous in daily conversation, but are understudied in current neurobiological models of language. To comprehend an indirect speech act like this one, listeners must not only decode the lexical-semantic content o...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2020.598131
更新日期:2021-01-14 00:00:00
abstract::Over recent years, brain-computer interface (BCI) has emerged as an alternative communication system between the human brain and an output device. Deciphered intents, after detecting electrical signals from the human scalp, are translated into control commands used to operate external devices, computer displays and vi...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章,评审
doi:10.3389/fnhum.2018.00312
更新日期:2018-08-06 00:00:00
abstract::Dopamine has been implicated in the fine-tuning of complex cognitive and motor function and also in the anticipation of future rewards. This dual function of dopamine suggests that dopamine might be involved in the generation of active motivated behavior. The DRD2 TaqIA polymorphism of the dopamine D2 receptor gene (r...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00250
更新日期:2013-06-05 00:00:00
abstract::It is commonly assumed that positive mood improves human creativity and that the neurotransmitter dopamine might mediate this association. However, given the non-linear relation between dopamine and flexibility in divergent thinking (Akbari Chermahini and Hommel, 2010), the impact of mood on divergent kinds of creativ...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2012.00319
更新日期:2012-11-26 00:00:00
abstract::[This corrects the article on p. 3 in vol. 9, PMID: 25674060.]. ...
journal_title:Frontiers in human neuroscience
pub_type: 已发布勘误
doi:10.3389/fnhum.2015.00172
更新日期:2015-03-26 00:00:00
abstract::The probability of an event's occurrence affects event-related potentials (ERPs) on electroencephalograms. The relation between probability and potentials has been discussed by using a quantity called surprise that represents the self-information that humans receive from the event. Previous studies have estimated surp...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2017.00075
更新日期:2017-02-27 00:00:00
abstract::A RECENT OPINION ARTICLE (NEURAL OSCILLATIONS IN SPEECH: do not be enslaved by the envelope. Obleser et al., 2012) questions the validity of a class of speech perception models inspired by the possible role of neuronal oscillations in decoding speech (e.g., Ghitza, 2011; Giraud and Poeppel, 2012). The authors criticiz...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2012.00340
更新日期:2013-01-04 00:00:00
abstract:Background:Dreaming is a universal experience, yet there is considerable inter-individual variability in dream recall frequency (DRF). One dominant model, the "arousal-retrieval" model, posits that intra-sleep wakefulness is required for dream traces to be encoded into long-term storage, essentially proposing that a be...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2019.00370
更新日期:2019-10-15 00:00:00
abstract::The default mode network (DMN) has been widely defined as a set of brain regions that are engaged when people are in a "resting state" (left to themselves in a scanner, with no explicit task instruction). The network emerged as a scientific object in the early twenty-first century, and in just over a decade has become...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2014.00619
更新日期:2014-08-25 00:00:00
abstract::Older adults have difficulties in navigating unfamiliar environments and updating their wayfinding behavior when faced with blocked routes. This decline in navigational capabilities has traditionally been ascribed to memory impairments and dysexecutive function, whereas the impact of visual aging has often been overlo...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2020.552111
更新日期:2020-10-29 00:00:00
abstract::Previous functional MRI (fMRI) studies have shown that fragile X mental retardation 1 (FMR1) fragile X premutation allele carriers (FXPCs) exhibit decreased hippocampal activation during a recall task and lower inferior frontal activation during a working memory task compared to matched controls. The molecular charact...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2012.00297
更新日期:2012-10-30 00:00:00
abstract::Current theories of the pathophysiology of schizophrenia have focused on abnormal temporal coordination of neural activity. Oscillations in the gamma-band range (>25 Hz) are of particular interest as they establish synchronization with great precision in local cortical networks. However, the contribution of high gamma...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00088
更新日期:2013-03-26 00:00:00
abstract::A longstanding challenge in epilepsy research and practice is the need to classify synchronization patterns hidden in multivariate electroencephalography (EEG) data that is routinely superimposed with intensive noise. It is essential to select a suitable feature extraction method to achieve high recognition performanc...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2018.00396
更新日期:2018-10-02 00:00:00
abstract::Neuroimaging combined with transcranial magnetic stimulation (TMS) to primary motor cortex (M1) is an emerging technique that can examine motor-system functionality through evoked activity. However, because sensory afferents from twitching muscles are widely represented in motor areas the amount of evoked activity dir...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00554
更新日期:2013-09-17 00:00:00
abstract::[This corrects the article DOI: 10.3389/fnhum.2015.00098.]. ...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章,已发布勘误
doi:10.3389/fnhum.2019.00125
更新日期:2019-04-09 00:00:00
abstract::The present study was aimed at investigating different aspects of Executive Functions (EF) in children with Developmental Dyslexia (DD). A neuropsychological battery tapping verbal fluency, spoonerism, attention, verbal shifting, short-term and working memory was used to assess 60 children with DD and 65 with typical ...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2014.00120
更新日期:2014-03-07 00:00:00
abstract::In perceptual decision making the brain extracts and accumulates decision evidence from a stimulus over time and eventually makes a decision based on the accumulated evidence. Several characteristics of this process have been observed in human electrophysiological experiments, especially an average build-up of motor-r...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2020.00009
更新日期:2020-02-04 00:00:00
abstract::Reaction time testing is widely used in online computerized concussion assessments, and most concussion studies utilizing the metric have demonstrated varying degrees of difference between concussed and non-concussed individuals. The problem with most of these online concussion assessments is that they predominantly r...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2020.509091
更新日期:2020-10-01 00:00:00
abstract::Prior research with preschool children has established that dialogic or active book reading is an effective method for expanding young children's vocabulary. In this exploratory study, we asked whether similar benefits are observed when a robot engages in dialogic reading with preschoolers. Given the established effec...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2017.00295
更新日期:2017-06-07 00:00:00
abstract::Recent studies employing rapid sampling techniques have demonstrated that the resting state fMRI (rs-fMRI) signal exhibits synchronized activities at frequencies much higher than the conventional frequency range (<0.1 Hz). However, little work has investigated the changes in the high-frequency fluctuations between dif...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2014.00503
更新日期:2014-07-08 00:00:00
abstract::Recently, a growing body of data has revealed that beyond a dysfunction of connectivity among different brain areas in schizophrenia patients (SCZ), there is also an abnormal asymmetry of functional connectivity compared with healthy subjects. The loss of the cerebral torque and the abnormalities of gyrification, with...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章,评审
doi:10.3389/fnhum.2014.01010
更新日期:2014-12-22 00:00:00
abstract::During sleep, humans experience the offline images and sensations that we call dreams, which are typically emotional and lacking in rational judgment of their bizarreness. However, during lucid dreaming (LD), subjects know that they are dreaming, and may control oneiric content. Dreaming and LD features have been stud...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00836
更新日期:2013-12-10 00:00:00
abstract::Determining the compositional properties of surfaces in the environment is an important visual capacity. One such property is specular reflectance, which encompasses the range from matte to shiny surfaces. Visual estimation of specular reflectance can be informed by characteristic motion profiles; a surface with a spe...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2015.00579
更新日期:2015-10-21 00:00:00
abstract::Recent models on speech perception propose a dual-stream processing network, with a dorsal stream, extending from the posterior temporal lobe of the left hemisphere through inferior parietal areas into the left inferior frontal gyrus, and a ventral stream that is assumed to originate in the primary auditory cortex in ...
journal_title:Frontiers in human neuroscience
pub_type: 杂志文章
doi:10.3389/fnhum.2013.00629
更新日期:2013-10-02 00:00:00