What Is the Optimal Setting for a Continuous-Flow Left Ventricular Assist Device in Severe Mitral Regurgitation?

abstract：:Thirty-five patients undergoing open-heart surgery are reported. Cardiac index, mean arterial pressure, oxygen consumption, lactate, pyruvate, and lactate excess in the blood were measured. An inverse correlation of arterial pressure with oxygen consumption and lactate excess was found during perfusion. Comparison of ...

journal_title：Artificial organs

authors： Osipov VP,Khodas MJ,Dementjeva II,Pjatnitskaja GKh

更新日期：1982-08-01 00:00:00

abstract：:Improvements in implantable ventricular assist device (VAD) performance will be required to obtain patient outcomes that are comparable with those of heart transplantation. The HeartQuest VAD (WorldHeart, Oakland, CA, U.S.A.) is an advanced device, with full magnetic suspension of the rotor, designed to address specif...

journal_title：Artificial organs

authors： Bearnson GB,Jacobs GB,Kirk J,Khanwilkar PS,Nelson KE,Long JW

更新日期：2006-05-01 00:00:00

abstract：:In this study two aspects of hybrid functional electrical stimulation (FES) orthoses were investigated: joint motion constraints and FES control strategies. First, the effects of joint motion constraints on the gait of normal subjects were investigated using modern motion analysis systems, including electromyogram (EM...

journal_title：Artificial organs

authors： Yang L,Granat MH,Paul JP,Condie DN,Rowley DI

更新日期：1997-03-01 00:00:00

abstract：:A 53-year-old man was referred to our department with a history of cough, especially at night, for 3 months. He was found to have a huge retrosternal goiter. We applied a novel combined cervical and robot-assisted approach to resect this difficult goiter. Using the da Vinci robot system, the intrathoracic part of the ...

journal_title：Artificial organs

authors： Wang S,Xu S,Liu B

更新日期：2014-05-01 00:00:00

abstract：:Molecular biology has been moving swiftly toward clarifying the entire genome of organisms, including human. The human genome efforts that promote this transaction are characterized by the large-scale, high throughput production of data about the structure of the genome of the molecular level and its computer-assisted...

journal_title：Artificial organs

authors： Matsubara K

更新日期：1996-08-01 00:00:00

abstract：:Short-term diabetes was induced in male Wistar rats with streptozotocin injection. The effects of diabetes on latissimus dorsi (LD) muscle contractile and biochemical properties and acute cardiomyoplasty (CDM) were assessed and compared with data from 16 control rats. Isometric force, contractile properties, and fatig...

journal_title：Artificial organs

authors： De Angelis K,Senna S,Irigoyen MC,Cestari IA

更新日期：2004-04-01 00:00:00

abstract：:The outcome predictors of intra-aortic balloon pump (IABP) in patients who undergo mitral valve surgery remain unknown. This study aimed to retrospectively review valvular surgery in patients who received an IABP to identify the predictors of failure of IABP support and anticipate the necessary therapy. This retrospec...

journal_title：Artificial organs

authors： Liang M,Wang C,Feng K,Chen G,Wang K,Wu Z

更新日期：2020-08-01 00:00:00

abstract：:Modeling different treatment options before a procedure is performed is a promising approach for surgical decision making and patient care in heart valve disease. This study investigated the hemodynamic impact of different prostheses through patient-specific MRI-based CFD simulations. Ten time-resolved MRI data sets w...

journal_title：Artificial organs

authors： Hellmeier F,Nordmeyer S,Yevtushenko P,Bruening J,Berger F,Kuehne T,Goubergrits L,Kelm M

更新日期：2018-01-01 00:00:00

abstract：:The rotary blood pump will be an implantable left ventricular assist device (LVAD) in the near future. However, the best control method and the interrelationship between the rotary blood pump and native heart functions are unclear. An estimation was made of the native heart cardiac output from the change of an LVAD's ...

journal_title：Artificial organs

authors： Nakata K,Ohashi Y,Tayama E,Ohtsuka G,Takami Y,Mueller J,Glueck J,Nosé Y

更新日期：1998-05-01 00:00:00

abstract：:The optimal anticoagulation regimen for hemodialysis (HD) in patients with heparin-induced thrombocytopenia (HIT) has not been defined. Hemodiafiltration (HDF) adds a large convective component to HD, thereby changing the pharmacokinetics of most anticoagulants. Data on coagulation regimens for HDF are scant. We there...

journal_title：Artificial organs

authors： Mahieu E,Claes K,Jacquemin M,Evenepoel P,Op De Beek K,Bogaert AM,Kuypers D,Verhamme P,Meijers B

更新日期：2013-05-01 00:00:00

abstract：:Many patients all over the world suffer from acute wounds caused by traumas or burns. In most crucial cases, skin regeneration cannot be promoted spontaneously, and skin grafts are applied as the main treatment. However, this therapy has some drawbacks which motivate researchers to develop wound dressings. In this stu...

journal_title：Artificial organs

authors： Mohseni M,Shamloo A,Aghababaei Z,Vossoughi M,Moravvej H

更新日期：2016-08-01 00:00:00

abstract：:The goal of this study was to determine whether porcine islets encapsulated in hollow fibers made of AN69 copolymer can correct hyperglycemia in diabetic mice and provide normal tolerance to a glucose challenge. In vitro perifusion of hollow fibers demonstrated the rapid kinetics of insulin release in response to gluc...

journal_title：Artificial organs

authors： Delaunay C,Darquy S,Honiger J,Capron F,Rouault C,Reach G

更新日期：1998-04-01 00:00:00

abstract：:The aim of this study was to assess the in vivo performance of a new microaxial rotary blood pump developed for long-term intraportal implantation. The pump, measuring 7 mm in diameter, has a single stage impeller and is powered by a microelectric motor. The pump was implanted into the portal vein in 13 large white pi...

journal_title：Artificial organs

authors： Havlík R,Kerkhoffs W,Jiao LR,Schumacher O,Reul H,Habib N

更新日期：2001-05-01 00:00:00

abstract：:To date, single-needle (SN) hemodialysis (HD) requires a dialysis machine equipped with two blood pumps-one controlling arterial blood flow (Qb) and one controlling venous Qb. B. Braun has developed an innovative single-pump SN HD system. Therefore, usability is improved by reducing complexity. The aim of this study w...

journal_title：Artificial organs

authors： Bieser W,Welsch M,Jakob M,Meibaum J,Rodriguez DA,Wolff H,Marcelli D,Barth C

更新日期：2018-08-01 00:00:00

abstract：:Mechanical circulatory support (MCS) devices continue to be hampered by thrombotic adverse events (AEs), a consequence of device-imparted supraphysiologic shear stresses, leading to shear-mediated platelet activation (SMPA). In advancing MCS devices from design to clinical use, in vitro circulatory loops containing th...

journal_title：Artificial organs

authors： Li M,Walk R,Roka-Moiia Y,Sheriff J,Bluestein D,Barth EJ,Slepian MJ

更新日期：2020-06-01 00:00:00

abstract：:Magnevad II is an improved version of Magnevad I and both are fourth-generation axial flow left ventricular assist devices. A major simplification has been implemented and tested. Magnevad I used a magnetically suspended rotor requiring active axial control. Magnevad II is completely passive but otherwise similar. A s...

journal_title：Artificial organs

authors： Goldowsky M,Lafaro R,Reed G

更新日期：2005-10-01 00:00:00

abstract：:Wall shear stress on the pump casing cover was measured using a surface-mounted hot-film sensor. In addition, the shear stress distribution in the pump was qualitatively investigated by means of oil-film visualization. The characteristics of shear stress in the pump are discussed, including the results on the oil-film...

journal_title：Artificial organs

authors： Mizunuma H,Nakajima R

更新日期：2007-07-01 00:00:00

abstract：:This article reviews the clinical, biological, radiological, and pathological procedures and their respective indications for the practical diagnosis of the following various histological patterns of renal osteodystrophy: osteitis fibrosa due to parathyroid hormone (PTH) hypersecretion: osteomalacia or rickets due to ...

journal_title：Artificial organs

authors： Fournier A,Oprisiu R,Hottelart C,Yverneau PH,Ghazali A,Atik A,Hedri H,Said S,Sechet A,Rasolombololona M,Abighanem O,Sarraj A,El Esper N,Moriniere P,Boudailliez B,Westeel PF,Achard JM,Pruna A

更新日期：1998-07-01 00:00:00

abstract：:A review and analysis of 5,001 neonatal venoarterial (VA) extracorporeal membrane oxygenation (ECMO) cases showed that bacterial and fungal infection occurred in 147 (2.9%) and 26 (0.6%) patients, respectively, with an overall incidence of 3.5%. Bivariate analysis was used to compare infected infants with controls, ba...

journal_title：Artificial organs

authors： Douglass BH,Keenan AL,Purohit DM

更新日期：1996-03-01 00:00:00

abstract：:A comparative assessment has been made regarding efficacy and safety of the double filtration plasmapheresis (DFPP), thermofiltration (TFPP), and low-density lipoprotein (LDL) adsorptive (PA) methods by making a crossover test on heterozygous familial hypercholesterolemia patients. Treatments by DFPP, TFPP (secondary ...

journal_title：Artificial organs

authors： Suzuki M,Yamane S,Matsugane T,Nobuto T,Azuma N,Nishide T,Shinomiya M,Saito K,Sasaki N,Nosé Y

更新日期：1996-04-01 00:00:00

abstract：:Experimental studies on the effects of scaling on the performance of centrifugal blood pumps were conducted in a closed-loop test rig. For the prototype, eight different impellers of the same outer diameter of 25 mm were tested at 1,500, 2,000, and 2,500 revolutions per minute (rpm) using blood analog as fluid medium....

journal_title：Artificial organs

authors： Wong YW,Chan WK,Yu SC,Chua LP

更新日期：2002-11-01 00:00:00

abstract：:Secondary flow in the centrifugal blood pump helps to enhance the washout effect and to minimize thrombus formation. On the other hand, it has an adverse effect on pump efficiency. Excessive secondary flow may induce hemolytic effects. Understanding the secondary flow is thus important to the design of a compact, effi...

journal_title：Artificial organs

authors： Watanabe N,Masuda T,Iida T,Kataoka H,Fujimoto T,Takatani S

更新日期：2005-01-01 00:00:00

abstract：:Cybernetics-based concepts can allow for complete independence for paralyzed individuals, including sensory motor recovery. Spinal cord injuries are responsible for a huge stress on health and a financial burden to society. This article focuses on novel procedures such as functional diagnosis for paraplegics and tetra...

journal_title：Artificial organs

authors： Varoto R,Cliquet A Jr

更新日期：2015-10-01 00:00:00

abstract：:The determination of when to stop extracorporeal membrane oxygenation (ECMO) rests upon demonstration of the return of adequate cardiac function to support vital organs and permit subsequent recovery. In general, patients with myocardial stun will recover function within several days. Factors that limit recovery inclu...

journal_title：Artificial organs

authors： Steinhorn DM

更新日期：1999-11-01 00:00:00

abstract：:EXTEND (EXTra-uterine Environment for Neonatal Development) is a novel system for supporting extremely premature infants that replicates in utero conditions by maintaining a sterile fluid environment and providing gas exchange via a pumpless arteriovenous oxygenator circuit connected to the umbilical vessels. Target g...

journal_title：Artificial organs

authors： Hornick MA,Mejaddam AY,McGovern PE,Hwang G,Han J,Peranteau WH,Partridge EA,Davey MG,Flake AW

更新日期：2019-12-01 00:00:00

abstract：:To assess the influence of hydration state on plasma volume (PV) changes during ultrafiltration, 11 clinically normhydrated patients on maintenance hemodialysis were studied intraindividually during 2 hydration states differing by 2-15% of lean body mass (LBM). Plasma volume was measured continually during a 15-min ul...

journal_title：Artificial organs

authors： Wizemann V,Leibinger A,Mueller K,Nilson A

更新日期：1995-05-01 00:00:00

abstract：:Our objective was to assess the effect of nitric oxide added to the sweep gas of the oxygenator during cardiopulmonary bypass (CPB) in infants on platelet count, platelet function, clinical outcomes, and safety. A randomized, double-blinded, placebo-controlled clinical trial in infants less than a year of age undergoi...

journal_title：Artificial organs

authors： Niebler RA,Chiang-Ching H,Daley K,Janecke R,Jobe SM,Mitchell ME,Varner C,Woods K,Scott JP

更新日期：2020-08-01 00:00:00

abstract：:The purified water supplies and randomly selected dialysates of 51 chronic and acute dialysis centers in the central United States were surveyed to assess the relative risks to dialysis patients from microbial and endotoxin contamination. A culture medium more sensitive than those generally employed in routine quality...

journal_title：Artificial organs

authors： Klein E,Pass T,Harding GB,Wright R,Million C

更新日期：1990-04-01 00:00:00

abstract：:Neurologic complications during neonatal extracorporeal life support (ECLS) are associated with significant morbidity and mortality. Gaseous microemboli (GME) in the ECLS circuit may be a possible cause. Advances in neonatal circuitry may improve hemodynamic performance and GME handling leading to reduction in patient...

journal_title：Artificial organs

authors： Glass K,Trivedi P,Wang S,Woitas K,Kunselman AR,Ündar A

更新日期：2017-04-01 00:00:00

abstract：:The purpose was to evaluate the cytotoxicity of two novel formulations (alpha and beta) of calcium phosphate cements. Positive control, represented by a commercial hydroxyapatite cement, and negative control were included for comparative purposes. A continuous lineage of fibroblastic cells was used, and the effect of ...

journal_title：Artificial organs

authors： Rossa C Jr,Marcantonio E Jr,Santos LA,Boschi AO,Raddi MS

更新日期：2005-02-01 00:00:00