Abstract:
BACKGROUND:The aim of this study was to investigate the role of oxidative stress in the pathology of ovine dicrocoeliasis. METHODS:During Dec 2013 - Oct 2014, seventy-two sheep (1-3 years) with liver dicrocoeliasis along with 47 healthy sheep were selected from animals admitted for slaughtering at slaughterhouse located in Neyshabour, Razavi Khorasan Province, Iran. RESULTS:In comparison to healthy control, the malondialdehyde (MDA) level and serum total antioxidant capacity were significantly higher in the parasitized group (P<0.05). A significant increase in liver MDA concentration (P<0.05) of parasitized group was also observed. Packed cell volume (PCV), zinc, iron, total bilirubin and albumin sera levels were significantly lower in the parasitized group (P<0.05). In parasitized sheep, a significant positive correlation was seen between serum MDA concentration and the activity of aspartate aminotransferase (AST). On the other hand, the concentration of serum MDA was inversely correlated with the value of PCV. No significant differences were observed for MDA concentration and total antioxidant capacity between normal and abnormal hepatic lobes in the parasitized animals. Oxidative stress markers (MDA and total antioxidant capacity in serum and liver samples) showed no significant correlations with the extent of pathological lesions and serum variables of liver injury in the parasitized sheep. No significant correlation was observed between oxidative stress markers and the fluke's number in the parasitized animals. CONCLUSION:Oxidative stress may play an important role in the erythrocyte destruction in sheep naturally infected with D. dendriticum. However, no clear relationships were observed between the oxidative stress, hepatic damage and parasite burden.
journal_name
Iran J Parasitoljournal_title
Iranian journal of parasitologyauthors
Samadieh H,Mohammadi GR,Maleki M,Borji H,Azizzadeh M,Heidarpour Msubject
Has Abstractpub_date
2017-01-01 00:00:00pages
46-55issue
1eissn
1735-7020issn
2008-238Xjournal_volume
12pub_type
杂志文章abstract:BACKGROUND:The intraperitoneal injection is a common method for establishing the experimental animal model infected with parasites. The aim of this study was to investigate if the intraperitoneal injection was another route of Trichinella spiralis infection. METHODS:From June to July 2015, twenty BALB/c mice were intr...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2017-01-01 00:00:00
abstract::Hydatid cyst caused by Echinococcus granulosus usually involves lung and liver but can appear in other organs. We report a 29-yr-old woman presented to Fatemi Hospital, Ardabil, Iran in 2017 with progressive painful swelling of the left gluteus which in imaging showed hydatid cyst. The cyst was successfully en blocked...
journal_title:Iranian journal of parasitology
pub_type:
doi:
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:Echinococcosis is a zoonotic parasitic disease of humans and various herbivorous domestic animals transmitted by the contact with domestic and wild carnivores, mainly dogs and foxes. The aim of this study is the production, purification and evaluation immunogenicity of new construction of EG95 protein. METH...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2014-10-01 00:00:00
abstract:BACKGROUND:Visceral leishmaniasis (VL) and cutaneous leishmaniasis (CL) are important public health problems in Iran. We aimed to evaluate the diagnostic potential of Western blot (WB) compared with indirect immunofluorescence test (IFAT) to serodiagnosis of leishmaniasis. METHODS:This study was performed from 2010-20...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Schistosomiasis is a debilitating disease, infects millions of people in tropical and subtropical regions. This study assessed the situation of the urinary schistosomiasis among schoolchildren of the Alsaial Alsagair village, Sudan. METHODS:A cross-sectional survey was carried out in 2016, in the Alsaial Al...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2017-04-01 00:00:00
abstract::We describe a case of visceral leishmaniasis (VL) due to Leishmania tropica in a 50-year-old Iranian man lived in a VL-endemic area in southwest of Iran. The patient presented with a 3-month history of fever and splenomegaly. Clinical signs and serological findings were suggestive of VL. Spleen biopsy was taken from t...
journal_title:Iranian journal of parasitology
pub_type:
doi:
更新日期:2016-01-01 00:00:00
abstract:Background:Toxoplasmosis is a common infection all around the world. During pregnancy; it may lead to congenital disorders or abortion in human and animals. Severe damage of toxoplasmosis indicates to require effective vaccine. One of dense granules antigen is GRA4 that secrete from tachyzoite and bradyzoite. GRA4 geno...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Leishmania Homologue of receptors for Activated C Kinase (LACK) antigen is a 36-kDa protein, which provokes a very early immune response against Leishmania infection. There are several reports on the expression of LACK through different life-cycle stages of genus Leishmania, but only a few of them have focus...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2014-10-01 00:00:00
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journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2016-07-01 00:00:00
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journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2015-07-01 00:00:00
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journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2014-04-01 00:00:00
abstract::Visceral leishmaniasis is a common parasitic disease between humans and animals, transmitted by sandflies (Phlebotomus) in the Mediterranean countries, including Iran. The statistics have been reported less than real due to errors in the diagnosis and reporting of affected cases. In this report, we will present the sy...
journal_title:Iranian journal of parasitology
pub_type:
doi:
更新日期:2020-04-01 00:00:00
abstract:Background:The protozoan parasite Theileria annulata is the causative agent of tropical theileriosis in cattle. Vaccination is recommended by administration of attenuated schizont-infected cell lines. The expected protective immunity post-vaccination can be demonstrated by challenge test through inoculation of highly v...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2019-10-01 00:00:00
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journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2015-10-01 00:00:00
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journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2018-10-01 00:00:00
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journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2014-03-01 00:00:00
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journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2014-03-01 00:00:00
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journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Cutaneous Leishmaniasis (CL) is a parasitic skin disease. Diagnosis primarily is based on clinical signs and microscopic observation of parasite on direct stained smears or tissue sections. Sensitivity of direct smear is not as high as molecular methods. The aim of this study was to identify and characterize...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2013-04-01 00:00:00
abstract:Background:Intestinal parasitic infections (IPIs) are among the most important etiologies of gastrointestinal disorders in developing countries. The present study was performed to determine the prevalence of IPIs in rural inhabitants of Fouman, northern Iran. Methods:Overall, 31 villages were randomly selected during ...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:The sole published data on feline heartworm infection in the Philippines was reported four decades ago. The study therefore endeavoured to assess and provide an update on the current status of heartworm infection in domesticated feline species using serologic and parasitological examination methods. METHODS...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
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journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
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journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract::Cases of Sparganum mansoni, caused by the plerocercoid larva of the tapeworm S. mansoni, occur throughout the world, particularly in Asian, Middle Eastern, and European countries. However, cases of infection with this parasite are rarely seen in Japan. Here, we present a case of a 61-year-old woman with a solitary sub...
journal_title:Iranian journal of parasitology
pub_type:
doi:
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:The leishmanicidal and cytotoxic activity of ten essential oils obtained from ten plant specimens were evaluated. METHODS:Essential oils were obtained by the steam distillation of plant leaves without any prior processing. Cytotoxicity was tested on J774 macrophages and leishmanicidal activity was assessed ...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
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journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2018-01-01 00:00:00
abstract:Background:Soil-transmitted helminth infections constitute a public health problem in the rural areas of tropical and subtropical regions, including Thailand. We aimed to determine the prevalence of soil-transmitted helminth infections and underlying risk factors among the schoolchildren living in the rural areas of so...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:10.18502/ijpa.v15i3.4210
更新日期:2020-07-01 00:00:00
abstract:Background:The larval stage of the tapeworm (cestode) Echinococcus granulosus is the etiological agent of hydatidosis or cystic echinococcosis, which is the zoonotic parasitic disease causing morbidity and mortality in both humans and livestock. Due to a lack of accurate data on the human isolates of E. granulosus in M...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2019-01-01 00:00:00
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journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Plasmodium vivax is the predominant species causes of malaria with about 90% total annual reported malaria in Iran. This study conducted to determine the susceptibility of Plasmodium vivax isolates to chloroquine in Sistan and Balochistan Province, southeastern Iran. METHODS:A total 270 subjects with sympto...
journal_title:Iranian journal of parasitology
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00