Hearing impairment, cochlear morphology, and peroxynitrite (ONOO(-)) formation in adult and aging NOS II knockout mice.

abstract：:Evidence for a common anatomical and physiological substrate for the generation of the background EEG and the vertex-evoked response led to the hypothesis that the EEG can be interpreted as the output from a time varying filter driven by (a) a noise generator responsible for the background activity, and (b) a pulse ge...

journal_title：Acta oto-laryngologica

authors： Salomon G,Barfod J

更新日期：1977-01-01 00:00:00

abstract：:Background: Increasing arterial stiffness is associated with atherosclerosis and there is an association between atherosclerosis and tinnitus may occur.Objectives: The aim of this study was to investigate the relationship between arterial stiffness and tinnitus using the central pulse-wave analysis method.Methods: Thi...

journal_title：Acta oto-laryngologica

authors： Gedikli Ö,Kemal O,Yıldırım U,Çeçen AB,Karabulut H,Akcay M,Terzi O

更新日期：2020-02-01 00:00:00

abstract：:Background: Chronic rhinosinusitis (CRS) is an inflammatory disease of the nose and the paranasal sinuses, often associated with an infection by Staphylococcus aureus (S. aureus). Disturbance in the function of ion channels is regarded as an etiological factor for pathogenesis of CRS. Aims: The study aims to measure t...

journal_title：Acta oto-laryngologica

authors： Saber A,Nakka SS,Hussain R,Hugosson S

更新日期：2019-07-01 00:00:00

abstract：:A total of 33 consecutively operated aural cholesteatomas were analysed with regard to preoperative findings and correlated with the morphology of the cholesteatoma tissue. Patients were found in all age groups, 9/33 of the patients were operated at an age below 15 years. A persistent ear discharge had occurred in all...

journal_title：Acta oto-laryngologica

authors： Anniko M,Mendel L

更新日期：1981-03-01 00:00:00

abstract：:Previous studies have shown that cystic fibrosis (CF) gene mutations are linked to several severe chronic infections. Chronic sinusitis is one condition that may well be influenced by a mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene. We studied two prevalent CF mutations (AF508 and 394...

journal_title：Acta oto-laryngologica

authors： Hytönen M,Patjas M,Vento SI,Kauppi P,Malmberg H,Ylikoski J,Kere J

更新日期：2001-12-01 00:00:00

abstract：CONCLUSION:The results of this study give support to the theory that opening the middle ear (ME) to the atmosphere leads to a deterioration in its pressure regulation capacity. However, this is probably not the reason why a perforation of the tympanic membrane becomes chronic. OBJECTIVE:Direct, continuous measurement ...

journal_title：Acta oto-laryngologica

authors： Brattmo M,Tideholm B,Carlborg B

更新日期：2005-07-01 00:00:00

abstract：CONCLUSIONS:In our study setting nitrous oxide (N(2)O) did not show any clinical benefit in discomfort experienced when applying local anesthesia for nasal operations. Further studies with longer inhalation times are needed to elucidate the role of N(2)O in application of local anesthesia in nasal surgery. OBJECTIVES:...

journal_title：Acta oto-laryngologica

authors： Starck M,Tarkkila P,Mäkitie AA,Ylikoski JS,Bäck LJ

更新日期：2008-07-01 00:00:00

abstract：:To investigate the pathogenesis of swimmers' sinusitis we questioned and examined a group of 20 swimmers and 20 controls. Clinical examination was followed by rhinomanometry, sonography of the maxillary sinuses, a saccharine test to assess mucociliary transport in the nose, and a viable cytological sampling of the nas...

journal_title：Acta oto-laryngologica

authors： Deitmer T,Scheffler R

更新日期：1990-09-01 00:00:00

abstract：:Background: Lermoyez syndrome (LS) is a rare auditory disorder, the details of LS remain unclear.Objectives: To investigate the grades of endolymphatic hydrops (ELH) and clinical characteristics of clinically diagnosed LS.Material and methods: Nine patients with clinically diagnosed LS were included. three-dimensional...

journal_title：Acta oto-laryngologica

authors： Zhou F,Shi S,Wang D,Guo P,Wang W

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVE:To improve the efficacy of intratympanic therapy using perilymphatic entry through the round window membrane. MATERIAL AND METHODS:The perilymphatic entry characteristics of 2 neutral molecules, mannitol (182.2 Da) and inulin (7,000 Da), were studied. A polyethylene catheter was placed in contact with the gu...

journal_title：Acta oto-laryngologica

authors： Chelikh L,Teixeira M,Martin C,Sterkers O,Ferrary E,Couloigner V

更新日期：2003-01-01 00:00:00

abstract：:There is no single technique for reconstruction of the canal wall following radical mastoidectomy. Autograft tissues may be unsuitable because of resorption and limited availability. An ideal foreign implant material should be bone-like in quality, non-ototoxic, readily available and malleable. Plaster of Paris, a deg...

journal_title：Acta oto-laryngologica

authors： Högset O,Bredberg G

更新日期：1986-05-01 00:00:00

abstract：OBJECTIVES:The authors would like to confirm a fluid pathway from the scala tympani to the organ of Corti, and to observe its morphological changes. METHODS:A staining solution for succinic dehydrogenase was perfused with phenazine methosulfate in the scala tympani of living guinea pigs (n = 5) under deep anesthesia. ...

journal_title：Acta oto-laryngologica

authors： Nomura Y,Kimura Y,Kobayashi H

更新日期：2016-11-01 00:00:00

abstract：:Topical application of FGF (fibroblast growth factor), a potent mitogen for mesodermal and neuroectodermal cells, was given to promote the healing of tympanic membrane perforations in rats. Calibrated tympanic membrane perforations were performed in 30 rats. At day 0, each rat received 40 microliters of placebo in the...

journal_title：Acta oto-laryngologica

authors： Mondain M,Saffiedine S,Uziel A

更新日期：1991-01-01 00:00:00

abstract：CONCLUSIONS:Endoscopic laser microsurgery (ELM) provides comparable oncological outcomes, and improved functional recovery and laryngeal preservation compared with open partial laryngopharyngectomy (OPLP) in patients with early squamous cell carcinoma of the hypopharynx (HPSCC). The use of open surgery is declining. Th...

journal_title：Acta oto-laryngologica

authors： Kuo CL,Lee TL,Chu PY

更新日期：2013-10-01 00:00:00

abstract：:The basement membrane zone (BMZ) of the epithelium of the vocal folds was investigated electron microscopically in 10 patients suffering from various benign lesions and in 3 controls. Various defects were observed: a thickening by deposition of electron dense material, a loss of normal architecture, and a near absence...

journal_title：Acta oto-laryngologica

authors： Dikkers FG,Hulstaert CE,Oosterbaan JA,Cervera-Paz FJ

更新日期：1993-01-01 00:00:00

abstract：:Intracellular calcium concentrations ([Ca2+]i) in type I cochlear spiral ganglion cells (SGCs) of the guinea pig were measured by digital imaging microscopy and the Ca(2+)-sensitive dye Fura-2. Extracellular ATP induced elevation of [Ca2+]i in type I SGCs in a concentration-dependent manner. The ATP-induced elevation ...

journal_title：Acta oto-laryngologica

authors： Cho H,Harada N,Yamashita T

更新日期：1997-07-01 00:00:00

abstract：OBJECTIVE:To determine the clinical usefulness of the dichotic multiple-frequency (MF) auditory steady-state response (ASSR) technique for estimating normal hearing compared to a 0.5-kHz tone burst and broadband click auditory brainstem response (ABR) protocol in a sample of adults. MATERIAL AND METHODS:A comparative ...

journal_title：Acta oto-laryngologica

authors： Swanepoel D,Schmulian D,Hugo R

更新日期：2004-01-01 00:00:00

abstract：:IL2Rs, in the presence of IL2, mediate activation and proliferation of human normal lymphocytes and modulate functional changes of some human leukocytic malignancies. IL2Rs have been demonstrated also on human neoplastic and fetal non-hematologic cells in vitro, although their functional role has not been described. W...

journal_title：Acta oto-laryngologica

authors： Cortesina G,Sacchi M,Galeazzi E,Johnson JT,Whiteside TL

更新日期：1992-01-01 00:00:00

abstract：:One hundred and fifty-five patients with complaints indicating acute sinusitis were examined and their symptoms and signs registered. The final diagnosis--maxillary sinus empyema versus not empyema--was established by means of antral aspiration. A computer-based analysis of clinical data demonstrated the significance ...

journal_title：Acta oto-laryngologica

authors： Berg O,Carenfelt C

更新日期：1988-03-01 00:00:00

abstract：:A retrospective study was carried out on repeated audio-vestibular examinations in 53 patients with unilateral Meniere's disease, between the vertiginous spells. Most patients showed no change in the caloric response reduction of the afflicted ear in the subsequent tests compared with the first one. These patients had...

journal_title：Acta oto-laryngologica

authors： Hulshof JH,Baarsma EA

更新日期：1981-11-01 00:00:00

abstract：BACKGROUND:The role of endonasal endoscopic surgery and radiotherapy in the treatment of skull base chordomas remains unclear. OBJECTIVE:We investigated the effect of endonasal endoscopic surgery and radiotherapy as treatment for skull base chordomas. METHOD:We investigated 46 patients (2006-2018) treated at the Affi...

journal_title：Acta oto-laryngologica

authors： Li H,Zhang H,Hu L,Wang H,Wang D

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVE:We present for the first time evidence that vestibulopathy impairs coordination of the head with the body center of gravity (CG) during free speed gait over ground. Vestibulopathic individuals demonstrate uncoordinated movement and gait due, at least in part, to impaired head stability and visual fixation. Ve...

journal_title：Acta oto-laryngologica

authors： Patten C,Horak FB,Krebs DE

更新日期：2003-01-01 00:00:00

abstract：:This study was designed to investigate morphological changes in the tympanic membrane (TM) associated with cholesteatoma formation in experimental animals following application of propylene glycol to the middle ear. A 50% solution of propylene glycol was applied bilaterally to the middle ear cavities of 30 young-adult...

journal_title：Acta oto-laryngologica

authors： Masaki M,Wright CG,Lee DH,Meyerhoff WL

更新日期：1989-07-01 00:00:00

abstract：:Simultaneous monitoring in human subjects on the same ear of eardrum displacement by tympanomanometry, and impedance with the electroacoustic bridge, provided information concerning contraction of the stapedius muscle and its effect on eardrum displacement. Extensive control procedures were employed to elicit only the...

journal_title：Acta oto-laryngologica

authors： Yonovitz A,Harris JD

更新日期：1976-01-01 00:00:00

abstract：:Multimodality therapy of advanced malignant tumours of the head and neck includes surgery, radiotherapy and chemotherapy. However, the cure rate for these tumours is low and guidelines for the selection and timing of therapy are needed. For such guidelines, tumour cell kinetic parameter studies, e.g. cell proliferatio...

journal_title：Acta oto-laryngologica

authors： Wennerberg J,Tropé C,Biörklund A

更新日期：1983-01-01 00:00:00

abstract：CONCLUSIONS:The distortion product otoacoustic emission (DPOAE) amplitudes in diabetics were significantly lower than those in controls when pure tone audiometry (PTA) was within normal limits, implying cochlear function impairment in the early stage of diabetes mellitus. Retrocochlear damage was suggested by elongated...

journal_title：Acta oto-laryngologica

authors： Hao J,Fu X,Zhang C,Zhang X,Zhao S,Li Y

更新日期：2017-02-01 00:00:00

abstract：CONCLUSION:The addition of transoral robotic surgery (TORS) in the diagnostic management of patients classified with head and neck squamous cell carcinoma of unknown primary (SCCUP) is promising and appears to improve detection rates of the primary tumour. The approach presented in this first Scandinavian study could p...

journal_title：Acta oto-laryngologica

authors： Channir HI,Rubek N,Nielsen HU,Kiss K,Charabi BW,Lajer CB,von Buchwald C

更新日期：2015-01-01 00:00:00

abstract：:There have been many morphological investigations on the generation of respiratory epithelium. However, the mucociliary activity of fetal respiratory epithelium has never yet been discussed. In the present work, ciliary activity and mucociliary function in the nose and the trachea of fetal rabbits were studied and, mo...

journal_title：Acta oto-laryngologica

authors： Ohashi Y,Nakai Y

更新日期：1984-03-01 00:00:00

abstract：CONCLUSIONS:In skilled hands, selective embolization is a safe procedure and represents an effective treatment for prolonged epistaxis. Embolization therapy can be repeated if necessary. OBJECTIVE:Severe posterior epistaxis is a common clinical problem in an ENT department and controlling the bleeding may present diff...

journal_title：Acta oto-laryngologica

authors： Andersen PJ,Kjeldsen AD,Nepper-Rasmussen J

更新日期：2005-03-01 00:00:00

abstract：:Cochlear microphonics (CM) were recorded in the guinea pig using differential recording from the first and third cochlear turns as well as by using a 10-electrode array inserted in the scala tympani of the basal turn. The excitation profile as represented by the CM was quantified by amplitude and phase data, and was m...

journal_title：Acta oto-laryngologica

authors： de Brey HB,Eggermont JJ

更新日期：1978-05-01 00:00:00