Biocompatible Amniotic Sac Implant Maintains a Scar-Free Brain Surface During Recurrent Glioma Surgery.

Abstract:

BACKGROUND:Dissection of brain surface adhesions during recurrent glioma surgery carries a risk of injury to cortical vessels and important surface vessels. We present our experience with the use of BioD film, a biocompatible amniotic membrane implant, to help prevent postoperative adhesions. We describe a novel method for preventing postoperative adhesions after high-grade glioma surgery using BioD film. METHODS:Amniotic sac implants were laid on the brain surface after resection of gliomas located near major surface arteries (sylvian fissure) and major veins (parasagittal convexity). Seven cases involved reoperation for tumor recurrence. RESULTS:In all 7 of the cases requiring reoperation, a new arachnoid-like surface layer was formed without any dural adhesions. The newly formed layer allowed for easy and simple dissection and mobilization of surface vessels while avoiding any trauma to the cortex. CONCLUSIONS:Amniotic sac implants have a promising role in preventing most surgical brain adhesions associated with recurrent glioma surgery, reducing the risks of cortical vessel and tissue injury.

journal_name

World Neurosurg

journal_title

World neurosurgery

authors

Saad H,Krisht KM,Yang WH,Lopez-Gonzalez MA,Aboud E,Krisht AF

doi

10.1016/j.wneu.2017.07.143

subject

Has Abstract

pub_date

2017-11-01 00:00:00

pages

308-313

eissn

1878-8750

issn

1878-8769

pii

S1878-8750(17)31243-3

journal_volume

107

pub_type

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