Abstract：
:Animal and human studies provide evidence that exposure to the endocrine disrupting chemical (EDC), bisphenol A (BPA), can lead to neurobehavioral disorders. Consequently, there is an impetus to identify safer alternatives to BPA. Three bisphenol compounds proposed as potential safer alternatives to BPA are bisphenol S (BPS), bisphenol F (BPF), and bisphenol AF (BPAF). However, it is not clear whether these other compounds are safer in terms of inducing less endocrine disrupting effects in animals and humans who are now increasingly coming into contact with these BPA-substitutes. In the past few years, several animal studies have shown exposure to these other bisphenols induce similar neurobehavioral disruption as BPA. We will explore in this review article the current studies suggesting these other bisphenols result in neuroendocrine disruptions that may be estrogen receptor-dependent. Current work may aide in designing future studies to test further whether these BPA-substitutes can act as neuroendocrine disruptors.
journal_name
Front Neuroendocrinoljournal_title
Frontiers in neuroendocrinologyauthors
Rosenfeld CSdoi
10.1016/j.yfrne.2017.08.001subject
Has Abstractpub_date
2017-10-01 00:00:00pages
123-133eissn
0091-3022issn
1095-6808pii
S0091-3022(17)30044-4journal_volume
47pub_type
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journal_title：Frontiers in neuroendocrinology
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journal_title：Frontiers in neuroendocrinology
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journal_title：Frontiers in neuroendocrinology
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journal_title：Frontiers in neuroendocrinology
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journal_title：Frontiers in neuroendocrinology
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journal_title：Frontiers in neuroendocrinology
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journal_title：Frontiers in neuroendocrinology
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journal_title：Frontiers in neuroendocrinology
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journal_title：Frontiers in neuroendocrinology
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journal_title：Frontiers in neuroendocrinology
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