Porcine 2', 5'-oligoadenylate synthetase 2 inhibits porcine reproductive and respiratory syndrome virus replication in vitro.

abstract：:Establishment of pulmonary Mycobacterium tuberculosis infection requires evasion of host innate defenses. In the lung alveoli, epithelial cells naturally resist uptake by the inhaled bacilli while macrophages patrol the epithelial surface and phagocytose foreign microbes. Alveolar microvascular endothelial cells, howe...

journal_title：Microbial pathogenesis

authors： Mehta PK,Karls RK,White EH,Ades EW,Quinn FD

更新日期：2006-08-01 00:00:00

abstract：:Multidrug resistance due to the expression of extended spectrum β-lactamases (ESBLs) by bacterial pathogens is an alarming health concern with huge socio-economic burden. Here, 102 bacterial isolates from Wastewater treatment plants (WTPs) were screened for resistance to different antibiotics. Kirby-Bauer method and p...

journal_title：Microbial pathogenesis

authors： Hemlata,Bhat MA,Kumar V,Ahmed MZ,Alqahtani AS,Alqahtani MS,Jan AT,Rahman S,Tiwari A

更新日期：2020-12-08 00:00:00

abstract：:In vivo studies are crucial decision-maker step in order to translate in vitro data to an applied therapy. Considering this we describe a simple method that analyzes and quantifies biofilm formation inside the Galleria mellonella larvae. Toothbrush bristles were employed as an abiotic surface to mimic a medical device...

journal_title：Microbial pathogenesis

authors： Campos-Silva R,Brust FR,Trentin DS,Macedo AJ

更新日期：2019-12-01 00:00:00

abstract：:The gene clusters encoding various P-fimbriae (F7(1), F7(2), F9 and F11) were compared. Deletion plasmids that lack the gene encoding the fimbrillin were derived from these gene clusters. Introduction of these deletion plasmids into an E. coli K12 strain resulted in non-fimbriated cells that still showed mannose-resis...

journal_title：Microbial pathogenesis

authors： van Die I,Zuidweg E,Hoekstra W,Bergmans H

更新日期：1986-02-01 00:00:00

abstract：:Iron plays a central role at the interface of pathogen and host. The ability to sequester iron from a host not only reduces host immune defenses but also promotes pathogen virulence, leading to the occurrence of infectious disease. Recently, outer membrane protein OmpW was shown to protect bacteria against harsh envir...

journal_title：Microbial pathogenesis

authors： Zhang P,Ye Z,Ye C,Zou H,Gao Z,Pan J

更新日期：2020-01-01 00:00:00

abstract：:Helicobacter pylori (H. pylori), which is a spiral-shaped Gram-negative microaerobic bacterium, is a causative pathogen. The entry of H. pylori into gastric epithelial cells involves various host signal transduction events, and its virulence factors can also cause a variety of biological responses. In this study, AGS ...

journal_title：Microbial pathogenesis

authors： Matsunaga S,Nishiumi S,Tagawa R,Yoshida M

更新日期：2018-11-01 00:00:00

abstract：:Siderophores are low molecular weight molecules that allow bacteria to acquire iron from host cell proteins. 2,3-dihydroxybenzoic acid (DHBA) is the only known siderophore produced by the intracellular pathogen Brucella abortus. Here its role in virulence was assessed by evaluating the ability of a mutant with a disru...

journal_title：Microbial pathogenesis

authors： Parent MA,Bellaire BH,Murphy EA,Roop RM 2nd,Elzer PH,Baldwin CL

更新日期：2002-05-01 00:00:00

abstract：:Food-production animals were considered to be a major reservoir of antimicrobial-resistant bacteria and clinically relevant pathogens. The potential of commensal Escherichia coli from pigs as a source of opportunistic pathogens associated with extraintestinal infections in humans needs to be assessed. In this study, 1...

journal_title：Microbial pathogenesis

authors： Li Y,Ma X,Li C,Dai X,Zhang L

更新日期：2020-11-01 00:00:00

abstract：:Mycobacterium tuberculosis genome encodes several high and low molecular mass penicillin binding proteins. One such low molecular mass protein is DacB2 encoded by open reading frame Rv2911 of M. tuberculosis which is predicted to play a role in peptidoglycan synthesis. In this study we have tried to gain an insight in...

journal_title：Microbial pathogenesis

authors： Bourai N,Jacobs WR Jr,Narayanan S

更新日期：2012-02-01 00:00:00

abstract：:The hemA mutation reduces the virulence of Salmonella typhimurium for mice by at least 10(7)-fold, as measured by change in LD50. The hemA mutation does not appear to affect killing of salmonella in mice. The salmonella with the hemA mutation persist in the spleen and liver for 2 to 3 weeks following intravenous injec...

journal_title：Microbial pathogenesis

authors： Benjamin WH Jr,Hall P,Briles DE

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVES:The non-coding RNA rprA can increase the resistance to ampicillin in Escherichia coli. METHODS:Bacterial DNA was extracted by boiling method and then amplified using polymerase chain reaction (PCR) with two different primer sets. Recombinant pET28a/rprA-sense and -antisense plasmids were separately transfer...

journal_title：Microbial pathogenesis

authors： Sahni A,Hajjari M,Raheb J,Foroughmand AM,Asgari M

更新日期：2019-04-01 00:00:00

abstract：:Histophilus somni (H. somni) is a gram-negative bacterial pathogen that causes respiratory, reproductive, and central nervous system disease in cattle. The hallmark of systemic H. somni infection is diffused vasculitis that can lead to an acute central nervous system disease known as thrombotic meningoencephalitis (TM...

journal_title：Microbial pathogenesis

authors： Tiwari R,Sullivan J,Czuprynski CJ

更新日期：2009-09-01 00:00:00

abstract：:Recent studies based on sequence divergence in the ospC gene have identified limited subpopulations of B. burgdorferi associated with invasive human disease. Spirochetes with certain OspC types never cause human disease, while some others cause local infection at the primary skin site but do not hematogenously dissemi...

journal_title：Microbial pathogenesis

authors： Xu Y,Bruno JF,Luft BJ

更新日期：2003-12-01 00:00:00

abstract：CONTEXT:Hepatitis E virus (HEV) as a hepatotropic virus is one of the major global health concerns. Autochthonous HEV transmitted by oral fecal-route in poor sanitation conditions as well as vertical and rarely blood transfusion. HEV occurrence is more common in developing countries and recently increased in developed ...

journal_title：Microbial pathogenesis

authors： Karbalaie Niya MH,Rezaee-Zavareh MS,Ranaei A,Alavian SM

更新日期：2017-09-01 00:00:00

abstract：:Aeromonas hydrophila is one of the main causative agent of high mortality and significative economic losses in aquaculture and has become increasingly resistant to conventional antibiotics. One feasible alternative to control and treat it is the use of essential oils. This study aimed to evaluate A. hydrophila suscept...

journal_title：Microbial pathogenesis

authors： F Souza C,Baldissera MD,A Vaucher R,Lopes LQ,Vizzotto BS,Raffin RP,Santos RC,L da Veiga M,U M da Rocha MI,Stefani LM,Baldisserotto B

更新日期：2016-09-01 00:00:00

abstract：:The objective of this study was to comprehensively identify the target genes induced by acid stimulation in Salmonella, and to clarify the relativity of acid tolerance and antimicrobial peptide resistance. A clinical S. Typhimurium strain, S6, was selected and performed a transcriptome analysis under the acid toleranc...

journal_title：Microbial pathogenesis

authors： Cao L,Wang J,Sun L,Kong Z,Wu Q,Wang Z

更新日期：2019-11-01 00:00:00

abstract：:Mycoplasma hyopneumoniae is the etiological agent of enzootic pneumonia (EP), a widespread disease that causes major economic losses to the pig industry. The swine host response plays an important role in the outcome of M. hyopneumoniae infections. The whole proteome of newborn pig trachea (NPTr) epithelial cells infe...

journal_title：Microbial pathogenesis

authors： Leal Zimmer FMA,Moura H,Barr JR,Ferreira HB

更新日期：2019-12-01 00:00:00

abstract：:The ica operon and aap gene are important factors for Staphylococcus epidermidis biofilm formation. However, we found 15 out of 101 S. epidermidis strains isolated from patients had both the ica operon and the aap gene in the genome but could not form biofilms (ica(+)aap(+)/BF(-) isolates). Compared with standard stra...

journal_title：Microbial pathogenesis

authors： Wu Y,Liu J,Jiang J,Hu J,Xu T,Wang J,Qu D

更新日期：2014-11-01 00:00:00

abstract：:Lipopolysaccharide (LPS) is a major virulence factor of Gram-negative bacteria playing a major role in stimulating protective immune response in mammalian host. However, in many gram-negative bacterial infections, LPS also elicits immunopathology by inducing excessive inflammatory changes. P. multocida (Pm), a gram-ne...

journal_title：Microbial pathogenesis

authors： Periasamy S,Praveena PE,Singh N

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Cryptosporidiosis represents a major public health problem. This infection, caused by a protozoan parasite of the genus Cryptosporidium, has been reported worldwide as a frequent cause of diarrhoea. In the immunocompetent host, the typical watery diarrhea can be self-limiting. However, it is severe and chron...

journal_title：Microbial pathogenesis

authors： Chelbi H,Essid R,Jelassi R,Bouzekri N,Zidi I,Ben Salah H,Mrad I,Ben Sghaier I,Abdelmalek R,Aissa S,Bouratbine A,Aoun K

更新日期：2018-02-01 00:00:00

abstract：:The high incidence of bacterial respiratory infections has led to a focus on evaluating the human respiratory microbiome. Studies based on culture-based and molecular methods have shown an increase in the bacterial community that includes the bacterial phyla Firmicutes, Bacteroidetes, Actinobacteria, and Proteobacteri...

journal_title：Microbial pathogenesis

authors： Maleki A,Zamirnasta M,Taherikalani M,Pakzad I,Mohammadi J,Krutova M,Kouhsari E,Sadeghifard N

更新日期：2020-06-01 00:00:00

abstract：:The biodegradation of Aflatoxin B1 (AFB1) is an industry of increasing importance. Bacillus licheniformis BL-010 was isolated from the aflatoxin contaminated corn feed storage, and was shown to degrade AFB1 efficiently. Here we present the complete genome sequence of BL-010, the genome comprises 4,287,714 bp in a circ...

journal_title：Microbial pathogenesis

authors： He S,Feng K,Ding T,Huang K,Yan H,Liu X,Zhang Z

更新日期：2018-05-01 00:00:00

abstract：:Molecular prevalence of nine putative virulence factors in two more prevalent Brucella species in Iranian patients and livestock was investigated. During five years (2010-2015), 120 human and animal specimens were collected from three geographical areas of Iran. All samples were cultured in blood culture media and sub...

journal_title：Microbial pathogenesis

authors： Hashemifar I,Yadegar A,Jazi FM,Amirmozafari N

更新日期：2017-04-01 00:00:00

abstract：:Apoptosis was considered as one of the important host defense mechanisms against mycobacteria infection. In macrophage, the main target cell of Mycobacterium tuberculosis, apoptosis after infection could help kill the bacillus inside and process the antigens for further presentation and proper immune response. Here, w...

journal_title：Microbial pathogenesis

authors： Tang J,Zhan L,Qin C

更新日期：2016-04-01 00:00:00

abstract：:Photobacterium damselae subsp. damselae has been known as an opportunistic pathogen in fish and mammals. Human infectious cases are often very serious and occasionally fatal. We previously reportedtwo fatal cases caused by this subspecies where the patients developed multiple organ failure within 20-36 h after the ons...

journal_title：Microbial pathogenesis

authors： Takahashi H,Miya S,Kimura B,Yamane K,Arakawa Y,Fujii T

更新日期：2008-08-01 00:00:00

abstract：:The antigenic site normally situated in the EF loop of VP2 (2EF) of poliovirus type 2 (Lansing) [PV2 (L)] was expressed in 2EF or in the BC loop of VP1 (1BC) of PV1 (Mahoney) [PV1 (M)]. A hybrid virus expressing the site in 2EF of PV1 (M) is known to be neutralizable by PV2 (L)-specific antisera and to induce neutrali...

journal_title：Microbial pathogenesis

authors： Murdin AD,Mirzayan C,Kameda A,Wimmer E

更新日期：1991-01-01 00:00:00

abstract：:We analyzed here the complete genome sequences of a highly virulent Flavobacterium columnare Pf1 strain isolated in our laboratory. The complete genome consists of a 3,171,081 bp circular DNA with 2784 predicted protein-coding genes. Among these, 286 genes were predicted as antibiotic resistance genes, including 32 RN...

journal_title：Microbial pathogenesis

authors： Zhang Y,Zhao L,Chen W,Huang Y,Yang L,Sarathbabu V,Wu Z,Li J,Nie P,Lin L

更新日期：2017-10-01 00:00:00

abstract：:Three coagulase-negative Staphylococcus species (CNS) (Staphylococcus epidermidis, Staphylococcus xylosus and Staphylococcus hyicus), from the milk of cows with mastitis, were used to evaluate adherence to and internalization by bovine mammary epithelial cells, and to investigate involvement of host cell signal transd...

journal_title：Microbial pathogenesis

authors： Almeida RA,Oliver SP

更新日期：2001-11-01 00:00:00

abstract：:As a stationary-phase signal, indole is secreted in large quantities by Escherichia coli on enriched media and has been shown to control several genes; however, its impact on acid resistance remains to be studied in detail. Real-time quantitative reverse transcription-polymerase chain reaction analysis revealed that i...

journal_title：Microbial pathogenesis

authors： Hirakawa H,Hayashi-Nishino M,Yamaguchi A,Nishino K

更新日期：2010-09-01 00:00:00

abstract：:Porphyromonas gingivalis is capable of in vitro growth when iron sources are either complexed to hemin or host iron transport proteins, or exist in an inorganic form. This study examined the effect of these iron sources on outer membrane protein (OMP) expression in P. gingivalis W50. Hemin (iron) starved P. gingivalis...

journal_title：Microbial pathogenesis

authors： Bramanti TE,Holt SC

更新日期：1992-07-01 00:00:00