Heterotopic Ossification and Hypertrophic Scars.

Abstract:

:Burns and trauma cause superficial and deep soft tissue wounds that cannot heal to the preinjury state. Healing requires cell proliferation and differentiation into the injured tissue type, laying down extracellular matrix, often as collagens. Heterotopic ossification causes severe pain, nonhealing wounds, and restricted range of motion. Treatment includes radiation therapy, nonsteroidal anti-inflammatory drugs, bisphosphonates, and possibly surgical excision and prophylactic measures. Hypertrophic scars, nonosseous lesions caused by excessive collagen deposition, are often painful, functionally limiting, and aesthetically displeasing. Treatment includes CO2 laser application, steroid injections, and excision with skin grafting. This article reviews the management of these pathologic wounds.

journal_name

Clin Plast Surg

authors

Agarwal S,Sorkin M,Levi B

doi

10.1016/j.cps.2017.05.006

subject

Has Abstract

pub_date

2017-10-01 00:00:00

pages

749-755

issue

4

eissn

0094-1298

issn

1558-0504

pii

S0094-1298(17)30088-3

journal_volume

44

pub_type

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